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研究生:吳孟儒
研究生(外文):Meng-Ru Wu
論文名稱:以核磁共振質子密度加權影像為基底模擬超音波影像資料庫
論文名稱(外文):Simulation of Ultrasound Images from MR Proton Image
指導教授:江惠華江惠華引用關係
指導教授(外文):Huihua Kenny Chiang
學位類別:碩士
校院名稱:國立陽明大學
系所名稱:生醫光電工程研究所
學門:工程學門
學類:生醫工程學類
論文種類:學術論文
論文出版年:2009
畢業學年度:97
語文別:中文
論文頁數:58
中文關鍵詞:超音波影像質子密度核磁共振影像電腦模擬
外文關鍵詞:Ultrasound ImageProton DensityMRIComputer Simulation
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目前MRI及CT影像皆已達到全身3D影像資料的境界,然而超音波影像因受限於探頭尺寸、量測及操作環境,僅能達到局部器官組織的3D掃描。為建立超音波全身3D資料庫,作為臨床教學之用,且克服實際掃描影像之環境限制,本計畫提出創新性構想,擬藉由電腦模擬產生超音波影像3D資料庫,我們擬使用核磁共振造影(Magnetic Resonance Imaging ,MRI)切面影像為基底,利用MRI的質子密度加權影像(Proton Density Weighted Image, PDWI)具有呈現組織含水量的特性(質子密度訊號強度正比於軟組織的密度),使用超音波模擬軟體方式,利用MRI PDWI為基底模擬超音波對於各種軟組織介面回波訊號,產生超音波切面影像。結合US/MRI對應關係進而開發全身超音波3D影像資料庫,供日後超音波教學與臨床訓練使用。
MRI and CT images have achieved 3D image capability. Due to the probe size and measurements environment, ultrasound (US) 3D image scan could only be realized in limit application. The aim of this project is aim to build a whole body 3D US image database to resolve the practical limitation of US 3D scanning images. We proposed a novel approach to generate the computer-simulated US 3D image database of the whole body soft tissue. We prepare to use Proton Density Weighted Image (PDWI) to estimate the density of soft tissue and to simulate the ultrasonic echo signal, and reconstruct US 3D images and build MRI/US dual display system. We expect this system would be useful for clinical US teaching, and training.
第一章 緒論 1
1-1 研究背景 1
1-2 研究目的 2
1-3 過去相關研究 2
1-4 論文架構 6
第二章 原理與理論公式推導 7
2-1 聲壓波動方程式 7
2-2 散射場計算原理 9
2-3 入射場計算原理 11
2-4 接收訊號計算原理 14
第三章 實驗方法與工具 18
3-1 Field II介紹 18
3-1-1 反射點之設定 19
3-1-2 超音波發射與接收探頭參數之設定 19
3-1-3 探頭接收訊號 20
3-1-4 Point Spread Function(PSF) 23
3-2 PDWI前置處理 26
3-3 模擬超音波影像流程 27
3-4 整體實驗方法流程 30
第四章 實驗結果與討論 32
4-1 Proton Density與組織密度之間的關係 32
4-2 豬肝(Liver)模擬結果與實際切面結果 33
4-3 Fat/Muscle模擬結果與實際切面結果 36
4-4 豬腦(Brain)模擬結果與實際切面結果 39
4-5 豬腎(Kidney)模擬結果與實際切面結果 40
第五章 結論與未來研究方向 41
5-1 研究討論 41
5-2 未來研究方向 42
參考文獻 43
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