(3.239.33.139) 您好!臺灣時間:2021/03/07 23:39
字體大小: 字級放大   字級縮小   預設字形  
回查詢結果

詳目顯示:::

我願授權國圖
: 
twitterline
研究生:林玲君
研究生(外文):Lin Line-Jiun
論文名稱:白點症病毒對甲殼類升血糖荷爾蒙系統之影響:荷爾蒙基因表現與蛋白質含量之研究
論文名稱(外文):Effects of white spot syndrome virus on the crustacean hyperglycemic hormonesystem: Studies of hormone gene expression and protein levels
指導教授:李奇英
指導教授(外文):Lee Chi-Ying
學位類別:碩士
校院名稱:國立彰化師範大學
系所名稱:生物學系
學門:生命科學學門
學類:生物學類
論文種類:學術論文
論文出版年:2010
畢業學年度:98
語文別:中文
論文頁數:96
中文關鍵詞:甲殼類升血糖荷爾蒙白點症病毒三明治酵素連結免疫吸附測定法
外文關鍵詞:crustacean hyperglycemic hormonewhite spot syndrome virussadwichELISA
相關次數:
  • 被引用被引用:1
  • 點閱點閱:145
  • 評分評分:系統版面圖檔系統版面圖檔系統版面圖檔系統版面圖檔系統版面圖檔
  • 下載下載:0
  • 收藏至我的研究室書目清單書目收藏:1
近幾年的研究中已知道在克氏螯蝦 (Procambarus clarkii) 中共有六個 (類) 甲殼類升血糖荷爾蒙轉錄子,分別為:CHH1、CHH1-L、truncated-CHH1 (t-CHH1)、CHH2、CHH2-L及 t-CHH2,經序列分析認為此六個分子主要是由兩個 CHH 基因經由替代性剪接而產生。而本研究目的是探討病毒感染後,在克氏螯蝦的 CHH/CHH-L系統的反應。 在實驗中以即時定量 PCR 的方法,觀察白點症病毒 (White Spot Syndrome Virus, WSSV) 感染螯蝦後,宿主CHH/CHH-L 基因表現變化的時程;另外,也以西方墨漬法及三明治酵素連結免疫吸附測定法,觀察 WSSV 感染螯蝦後,宿主組織與血淋巴液中 CHH/CHH-L 蛋白質含量的時程變化。 由實驗結果發現 WSSV 感染後,克氏螯蝦血淋巴液中 CHH1 有升高的趨勢,而血糖也會誘發上升;另外,在螯蝦組織中也發現,當 WSSV 感染 24, 48 小時後,眼柄神經節中 CHH1 含量有顯著下降;而眼柄神經節之 CHH1 基因表現,於病毒感染後並無顯著地改變。除此之外,腦神經節與胸神經節對於病毒感染也有反應,這些組織之 CHH1 基因表現於感染 24, 48 小時後,均有顯著上升;腦神經節 CHH1 含量於感染 12, 24 小時亦有顯著下降,而胸神經節含量則無顯著地改變;病毒感染後宿主血球 CHH1 含量並無顯著改變。在 CHH-like peptides (CHH1-L 與CHH2-L) 方面,病毒感染 24, 48 小時後,會誘發螯蝦胸神經節 CHH1-L 基因表現上升,以西方墨漬偵測分析,發現在注射病毒後 CHH1-L 含量於 12 小時有顯著上升。另外,關於 CHH2-L,目前並無合適之抗體,可分析組織中 CHH2-L 含量之變化,僅以即時定量 PCR 分析組織中基因表現。以即時定量 PCR 分析發現,當 WSSV 感染 24, 48 小時後,螯蝦胸神經節與腦神經節 CHH2-L 基因顯著增加,在眼柄組織基因表現則無變化。 綜合以上的 CHH 與 CHH-like peptides 的趨勢,可以得知螯蝦在 WSSV 感染後,會活化 CHH/CHH-L 系統,使其基因表現與組織蛋白質含量改變,初步推測 CHH/CHH-L 系統可能參與螯蝦體內的免疫調節,幫助宿主在免疫防禦的過程裡,防止病原體的入侵。
Six transcripts, each encoding a distinct CHH (crustacean hyperglycemic hormone) or CHH-like (CHH-L) peptides, Procambarus clarkii - CHH1, CHH1-L, truncated-CHH1 (t-CHH1), CHH2, CHH2-L, and t-CHH2, were identified in the crayfish. These transcripts were generated by alternative splicing of RNA precursors of two CHH genes (chh1 and chh2). The present study examined the effects of white spot syndrome virus (WSSV) on the CHH and CHH-like peptide system. Hemolymph CHH1 levels were increased after WSSV infection, followed by a significant rise in hemolymph glucose levels; in addition, CHH1 protein levels in the eyestalk ganglia were significantly decreased 24 and 48 hr after infection, but its gene expression levels did not change significantly. On the other hand, CHH1 gene expression levels increased significantly 24 and 48 hr after infection in the thoracic ganglia and cerebral ganglia; CHH1 protein levels in the cerebral ganglia decreased significantly 12 and 24 hr after infection, whereas its levels in the thoracic ganglia or hemocyte did not change significantly after infection. With regard to CHH-like peptides (CHH1-L and CHH2-L), CHH1-L proteins levels and its gene expression levels in the thoracic ganglia were significantly increased 12 hr after infection, whereas CHH2-L gene expression levels were also significantly increased 24 and 48 hr after infection in the thoracic ganglia and cerebral ganglia, but not in the eyestalk ganglia. The combined results indicate that the CHH and CHH-L peptides systems are activated by WSSV, through enhancing their gene expression, release into hemolymph, or both. These WSSV-activated peptide systems might be involved in mediating adaptive processes (e.g., hyperglycemic response) in response to pathogen-related stresses or in the processes of immune defense against invading pathogens.
中文摘要 Ⅰ
Abstract Ⅱ
誌謝 Ⅲ
目錄 Ⅳ
壹、前言 1
貳、文獻探討 3
參、材料與方法 14
肆、結果 32
伍、討論 39
陸、結論 50
柒、參考文獻 51
表 67
圖 68
附件 86

吳素華。2005。甲殼類血球細胞中升血糖荷爾蒙之基因選殖與分子特徵研究。國立彰化師範大學生物學系研究所論文。
江佳穎。2008。螯蝦 (類) 甲殼類升血糖荷爾蒙基因:分子選殖及基因表現之組織分布和定量分析。國立彰化師範大學生物學系研究所論文。
張智鈞。2008。紅腳蟳 (Scylla olivacea) 兩種甲殼類升血糖荷爾蒙異構型特性、重組蛋白表現與功能之研究。國立彰化師範大學生物學系研究所論文。
宮珮真。2009。克氏螯蝦 (Procambarus clarkii) 甲殼類升血糖荷爾蒙之基因與轉錄子選殖與特徵研究。國立彰化師範大學生物學系研究所論文。
吳欣儒。2009。克氏螯蝦甲殼類升血糖荷爾蒙之純化、免疫偵測及質譜鑑定。國立彰化師範大學生物學系研究所論文。
Abramowitz A.A., Hisaw F.L. and Papandrea D.N. 1944. The occurrence of a diabetogenic factor in the eyestalks of crustacean. Biological Bulletin 86: 1-5.
Andrew R.D. 1983. Neurosecretory pathways supplying the neurohemal organs in crustacean. Neurohemal Organs of Arthropods (ed. Gupta AP), pp. 90-117.
Aguilar M.B., Soyez D., Falchetto R., Arnott D., Shabanowitz J., Hunt D.F. and Huberman A. 1995. Amino acid sequence of the minor isoform of the crustacean hyperglycemic hormone (CHH-II) of the Mexican crayfish Procambarus bouvieri (Ortmann): presence of a D-amino acid. Peptides 16: 1375-1383.
Audsley N., Mcintosh C. and Phillips J.E. 1992. Isolation of a neuropeptide from locust corpus cardiacum which influences ileal transport. Journal of Experimental Biology 173: 261-274.
Black D.L. 2000. Protein diversity from alternative splicing: a challenge for bioinformatics and post-genome biology. Cell 103:367-370.
Böcking D., Dircksen H. and Keller R. 2002. The crustacean neuropeptides of the CHH/MIH/GIH family: structure and biological activities. In The Crustacean Nervous System (ed. Wiese K), 84-97. Springer, Berlin, Heidelberg, New York.
Bulau P., Meisen I., Reichwein-Roderburg B., Peter-Katalinic J. and Keller R. 2003. Two genetic variants of the crustacean hyperglycemic hormone (CHH) from the Australian crayfish, Cherax destructor: detection of chiral isoforms due to posttranslational modification. Peptides 24: 1871-1879.
Chang E.S., Chang S.A., Beltz B.S. and Kravitz E.A. 1999a. Crustacean hyperglycemic hormone in the lobster nervous system: localization and release from cells in the subesophageal ganglion and thoracic second root. The Journal of Comparative Neurology 414: 50-56.
Chang E.S., Keller R. and Chang S.A. 1998. Quantification of crustacean hyperglycemic hormone by ELISA in hemolymph of the lobster, Homarus americanus, following various stresses. General and Comparative Endocrinology 111: 359-366.
Chen S.H., Lin C.Y. and Kuo C.M. 2004. Cloning of two crustacean hyperglycemic hormone isoforms in freshwater giant prawn (Macrobrachium rosenbergii): evidence of alternative splicing. Marine Biotechnology 6: 83-94.
Chou H.Y., Huang C. Y., Wang C. H., Kou G. H. and Lo C. F. 1995.Pathogenicity of a baculovirus infection causing white spot syndrome in cultured penaeid shrimp in Taiwan. Disease of Aquatic Organisms 23: 165-173.
Chung J.S., Zmora N., Katayama H. and Tsutsui N. 2010. Crustacean hyperglycemic hormone (CHH) neuropeptides family: Functions, titer, and binding to target tissues. General and Comparative Endocrinology 166: 447-454.
Chung J.S., Bembe S., Tamone S., Andrews E. and Thomas H. 2009. Molecular cloning of the crustacean hyperglycemic hormone (CHH) precursor from the X-organ and the identification of the neuropeptide from sinus gland of the Alaskan Tanner crab, Chionoecetes bairdi. General and comparative endocrinology 162: 129-133.
Chung J.S. and Webster S.G. 2008. Angiotensin-Converting Enzyme-Like Activity in Crab Gills and Its Putative Role in Degradation of Crustacean Hyperglycemic Hormone. Archives of Insect Biochemistry and Physiology 68:171-180.
Chung J.S. and Zmora N. 2008. Functional studies of crustacean hyperglycemic hormones (CHHs) of the blue crab, Callinectes sapidus: the expression and release of CHH in eyestalk and pericardial organ in response to environmental stress. FEBS Journal 275: 693-704.
Chung J.S. and Webster S.G. 2006. Binding sites of crustacean hyperglycemic hormone and its second messengers on gills and hindgut of the green shore crab, Carcinus maenas: A possible osmoregulatory role. General and Comparative Endocrinology 147: 206-213.
Chung J.S. and Webster S.G. 2003. Moult cycle-related changes in biological activity of moult-inhibiting hormone (MIH) and crustacean hyperglycaemic hormone (CHH) in the crab, Carcinus maenas: From target to transcript. European Journal of Biochemistry 270: 3280-3288.
Chung J.S., Dircksen H. and Webster S.G. 1999. A remarkable, precisely timed release of hyperglycemic hormone from endocrine cells in the gut is associated with ecdysis in the crab Carcinus maenas. Proceedings of the National Academy of Sciences of the United States of America 96: 13103-13107.
Chung J.S., Wilkinson M.C. and Webster S.G. 1998. Amino acid sequences of both isoforms of crustacean hyperglycemic hormone (CHH) and corresponding precursor-related peptide in Cancer pargurus. Regulartory Peptides 77: 17-24.
Chung J.S. and Webster S.G. 1996. Does the N-terminal pyroglutamate residue have any physiological significance for crab hyperglycemic neuropeptides? European Journal of Biochemistry 240: 358-364.
Cooke I.M. and Sullivan R.E. 1982. Hormones and neurosecretion. In The Biology of Crustacean, Vol. 3 (eds. Atwood HL and Sandeman DC), pp. 206-209.
Dai L., Zitnan D. and Adams M.E. 2007. Strategic expression of ion transport peptide gene products in central and peripheral neurons of insects. Journal of Computational Neuroscience 500: 353-367.
De Kleijn D.P., and Van Herp F. 1995. Molecular biology of neurohormone precursors in the eyestalk of Crustacea. Comparative Biochemistry & Physiology. Part B, Biochemistry & Molecular Biology 112: 573-579.
Dhar A.K., Bowers R.M., Licon K.S., Veazey G. and Read B. 2009. Validation of reference genes for quantitative measurement of immune gene expression in shrimp. Molecular Immunology 46: 1688-1695.
Dircksen H. 2008. Insect ion transport peptide are derived from alternatively spliced genes and differentially expressed in the central and peripheral nervous system. Journal of Experimental Biology 212: 401-412.
Dircksen H., Bocking D., Heyn U., Mandel C., Chung J.S., Baggerman G., Verhaert P., Daufeldt S., Plosch T., Jaros P.P., Waelkens E., Keller R. and Webster S.G. 2001. Crustacean hyperglycaemic hormone (CHH)-like peptides and CHH-precursor- related peptides from pericardial organ neurosecretory cells in the shore crab, Carcinus maenas, are putatively spliced and modified products of multiple genes. The Biochemical journal 356:159-170.
Edgerton B.F. 2004. Susceptibility of the Australian freshwater crayfish Cherax destructor albidus to white spot syndrome virus (WSSV). Disease of aquatic organisms 59: 187-193.
Escobedo-Bonilla C. M., Alday-Sanz V., Wille M., Sorgeloos P., Pensaert M.B. and Nauwynck H. J. 2008.A review on the morphology, molecular characterization, morphogenesis and pathogenesis of white spot syndrome virus. Journal of Fish Diseases 31: 1-18.
Fanjul-Moles M.L. 2006. Biochemical and functional aspects of crustacean hyperglycemic hormone in decapod crustaceans: Review and update. Comparative Biochemistry and Physiology 142: 390-400.
Flegel T.W. 1997. Special topic review: Major viral diseases of the black tiger prawn (Penaeus monodon) in Thailand World. Journal of Microbiology & Biotechnology 13: 433-442.
Ginzinger D.G. 2002. Gene quantification using real-time quantitative PCR An emerging technology hits the mainstream. Experimental Hematology 30: 503-512.
Goy, M.F. 1990. Activation of membrane guanylate cyclase by an invertebrate peptide hormone. Journal of Biological Chemistry 265: 20220-7.
Goy, M.F., Mandelbrot D.A. and York C.M. 1987. Identification and characterization of a polypeptide from a lobster neurosecretory gland that induces cyclic GMP accumulation in lobster neuromuscular preparations. Journal of Neurochemistry, 48:954-966.
Graveley B. R. 2001. Alternative splicing: increasing diversity in the proteomic world. Trends in Genetics 17, 100-107.
Gross P.S., Bartlett T.C., Browdy C.L., Chapman R.W. and Warr G.W. 2001. Immune gene discovery by expressed sequence tag analysis of hemocytes and hepatopancreas in the pacific white shrimp, Litopenaeus vannameu, and the Atlantic white shrimp, L. setiferus. Developmental and Comparative Immunology 25: 565-577.
Gu P.L. and Chan S.M. 1998. The shrimp hyperglycemic hormone-like neuropeptide is encoded by multiple copies of genes arranged in a cluster. FEBS letters 441:397-403.
He F., Syed S. M., Sahul Hameed A.S. and Kwang J. 2009. Viral ubiquitin ligase WSSV222 is required for efficient white spot syndrome virus replication in shrimp. Journal of General Virology, 90:1483-1490.
Hendrik M., Melanie M., Just M.V. and Marielle C.W. 2003. Transcriptional analysis of the white spot syndrome virus major virion protein genes. Journal of General Virology 84: 1517-1523.
Hossain M.S., Chakraborty A., Joseph B., Otta S.K., Karunasagar I. and Karunasagar I. 2001. Detection of new hosts for white spot syndrome virus of shrimp using nested polymerase chain reaction. Aquaculture 198:1-11.
Hsu Y.W., Weller J.R., Christie A.E. and de la Iglesia H.O. 2008. Molecular cloning of four cDNAs encoding prepro-crustacean hyperglycemic hormone (CHH) from the eyestalk of the red rock crab Cancer productus: identification of two genetically encoded CHH isoforms and two putative post-translationally derived CHH variants. General and Comparative Endocrinology 155: 517-525.
Hsu Y.W., Messinger D.I., Chung J.S.,Webster S.G., De la Iglesia H.O. and Christie A.E. 2006. Members of the crustacean hyperglycemic hormone (CHH) peptide family are differentially distributed both between and within the neuroendocrine organs of Cancer crabs: implications for differential release and pleiotropic function. Journal of Experimental Biology 209: 3241- 3256.
Huahua D., Wei D., Xinyan H., Weifen L., Yaxiang X. and Zirong X. 2008. Effect of low water temperature on viral replication of white spot syndrome virus in Procambarus clarkii. Aquaculture 277: 149-151.
Iwanaga S. and Lee B. L. 2005. Recent Advances in the Innate Immunity of Invertebrate Animals. Journal of Biochemistry and Molecular Biology Review 38: 128-150.
Jiravanichpaisal P., Sricharoen S., Söderhäll I. and Söderhäll K. 2006. White spot syndrome virus (WSSV) interaction with crayfish haemocytes. Fish & Shellfish Immunology 20: 718-727.
Jiravanichpaisal P., Bangyeekhun E., Söderhäll K. and Söderhäll I. 2001. Experimental infection of white spot syndrome virus in freshwater crayfish Pacifastacus leniusculus. Diseases of Aquatic Organisms 47: 151-157.

Johansson M.W., Keyser P., Sritunyalucksana K. and Söderhäll K. 2000. Crustacean haemocytes and haematopoiesis. Aquaculture 191: 45-52.
Katayama H. and Chung J.S. 2009. The specific binding sites of eyestalk- and pericardial organ-crustacean hyperglycaemic hormones (CHHs) in multiple tissues of the blue crab, Callinectes sapidus. The Journal of Experimental Biology 212: 542-549.
Katayama H., Ohira T., Aida K. and Nagasawa H. 2002. Significance of a carboxyl-terminal amide moiety in the folding and biological activity of crustacean hyperglycemic hormone. Peptides 23: 1537-1546.
Kung P.C., Wu S.H., Wu H.J. and Lee C.Y. Expression of diverse forms of transcripts encoding crustacean hyperglycemic hormone (CHH) and CHH-related peptides in hemocytes. (in preparation)
Keller R., Kegel G., Reichwein B., Sedlmeier D. and Soyez D. 1999. Biological effects of neurohormones of CHH/MIH/GIH peptide family in crustaceans. In Recent Developments in Comparative Endocrinology and Neurobiology (eds. Roubos EW, Wendelaar B, Vaudry H, De Loof A), pp. 209-212. Maastricht: Shaker.
Keller R. 1992. Crustacean neuropeptides : structure, functions, and comparative aspects. Experientia 48:439-448.
Khayat M., Yang W., Aida K., Nagasawa H., Tietz A., Funkenstein B. and Lubzens E. 1998. Hyperglycaemic hormones inhibit protein and mRNA synthesis in in vitro-incubated ovarian fragments of the marine shrimp Penaeus semisulcatus. General and Comparative Endocrinology 110: 307-318.
Kreil G. 1997. D-amino acids in animal peptides. Annual Rreview of Biochemistry 66: 337-345.
Lacombe C., Grève P. and Martin G. 1999. Overview on the sub-grouping of the crustacean hyperglycemic hormone family. Neuropeptides 33: 71-80.
Lee C. J. and Irizarry K. 2003. Alternative splicing in the nervous system: an emerging source of diversity and regulation. Biological psychiatry 54:771-776.
Lee S.Y. and Söderhäll K. 2002. Early events in crustacean innate immunity. Fish & Shellfish Immunology 12:421-437.
Lee C.Y., Yang P.F. and Zou H.S. 2001. Serotonergic regulation of crustacean hyperglycemic hormone secretion in the crayfish, Procambarus clarkii. Physiological and Biochemical Zoology 74:376-382.
Lehmann U. and Kreipe H. 2001. Real-time PCR analysis of DNA and RNA extracted from formalin-fixed and paraffin-embedded biopsies. Methods 25:409-418.
Lo C.F., Hsu H.C., Tsai M.-F., Ho C.H., Peng S.E., Kou G.H. and Lightner D.V. 1999. Specific DNA fragment analysis of different geographical clinical samples of shrimp white spot syndrome virus. Diseases of Aquatic Organisms 35:175-185.
Lo C.F., HO C.H., Peng S.E., Chen C.H, Hsu H.C., Chiu Y.L., Chang C.F., Liu K.F., Su M.S., Wang C.H. and Kou G.H. 1996. White spot syndrome baculovirus (WSBV) detected in cultured and captured shrimp, crabs and other arthropods. Disease of aquatic organisms 27: 215-225.
Loker E.S., Adema C.M., Zhang S.-M. and Kepler T.B. 2004. Invertebrate immune systems-Not homogeneous, not simple, not well understood. Immunological Reviews 198:10-24.
Lorenzon S., Edomi P., Giulianini P. G., Mettulio R. and Ferrero E. A. 2004. Variation of crustacean hyperglycemic hormone (cHH) level in the eyestalk and haemolymph of the shrimp Palaemon elegans following stress. The Journal of Experimental Biology 207:4205-13.
Lorenzon S., Pasqual P. and Ferrero E.A. 2002. Different bacterial lipopolysaccharides as toxicants and stressors in the shrimp Palaemon elegans. Fish and Shellfish Immunology 13: 27-45.
Lorenzon S., Francese M. and Ferrero E.A. 2000. Heavy metal toxicity and differential effects on the hyperglycemic stress response in the shrimp Palaemon elegans. Archives of Environmental Contamination and Toxicology 39: 167-176.
Lorenzon S., Giulianini P.G. and Ferrero E.A. 1997. Lipopolysaccharide- induced hyperglycemia is mediated by CHH release in crustaceans. General and Comparative Endocrinology 108, 395-405.
Komali M., Kalarani V., Venkatrayulu C.H. and Chandra Sekhara Reddy D. 2005. Hyperglycaemic effects of 5-hydroxytryptamine and dopamine in the freshwater prawn, Macrobrachium malcolmsonii. Journal of Experimental Zoology Part A: Comparative Experimental Biology 303A:448-455.
Mathew S., Kumar K.A., Anandan R., Nair P.G. and Devadasan K. 2007. Changes in tissue defence system in white spot syndrome virus (WSSV) infected Penaeus monodon Comparative Biochemistry and Physiology, Part C 145: 315- 320.
Meredith J., Ring M., Macins A., Marschall J., Cheng N.N., Theilmann D., Brock H.W. and Phillips J.E. 1996. Locust ion transport peptide (ITP): primary structure, cDNA and expression in a baculovirus system. The Journal of Experimental Biology 199: 1053-1061.
Mettulio R., Edomi P., Ferrero E.A., Lorenzon S. and Giulianini P.G.. 2004. The crustacean hyperglycemic hormone precursors a and b of the Norway lobster differ in the preprohormone but not in the mature peptide. Peptides 25: 1899-1907.
Michael A.J., Hugh Y.E. and Spencer D. 1973. Cytology e of Carcinus haemocytes and their function in carbohydrate metabolism. Comparative biochemistry and physiology 46: 569-581.
Michael A.J. and Spencer D. 1972. Carbohydrates of the hepatopancreas and blood tissue of Carcinus Comparative biochemistry and physiology 41: 433-433.
Michael A.J., Spencer D. and Hugh Y.E. 1970. Possible hepatic function for crustacean blood cells Nature 16: 471-472.
Michael A.J., Frank M. and Fisher J.R. 1968. Aspects of carbohydrate metabolism in crustacean. Biologival Bulletin 135: 424-425.
Mosco A., Edomi P., Guarnaccia C., Lorenzon S., Pongor S., Ferrero E.A. and Giulianini P.G. 2008. Functional aspects of CHH C-terminal amidation in crayfish species. Regulatory Peptides 147: 88-95.
Newcomb R.W. 1983. Peptides in the sinus gland of cardisoma carnifex: isolation and amino acid analysis. Journal of Comparative Physiology 153:207-221.
Ollivaux C. and Soyez D. 2000. Dynamics of biosynthesis and release of crustacean hyperglycemic hormone isoforms in the X-organ-sinus gland complex of the crayfish Orconectes limosus. European Journal of Biochemistry 267: 5106-5114.
Pikul J., Siripavee S., Irene S. and Kenneth S. 2006. White spot syndrome virus (WSSV) interaction with crayfish haemocytes. Fish and Shellfish Immunology 20: 718-727.
Pikul J., Eakaphun B., Kenneth S. and Irene S. 2001. Experimental infection of white spot syndrome virus in freshwater crayfish Pacifastacus leniusculus. Diseases of aquatic organisms 47: 151-157.
Pongsomboon S., Wongpanya R., Tang S., Chalorsrikul A. and Tassanakajon A. 2008. Abundantly expressed transcripts in the lymphoid organ of the black tiger shrimp, Penaeus monodon, and their implication in immune function. Fish & Shellfish Immunology 25: 485-493.
Prosser C.L. and Weinseein S.J. 1950. Comparison of blood volume in animals with open and closed circulatory systems. Physiological zoology 23: 113-124.
Reddy P. and Sainath S.B. 2009. Hyperglycemic hormone in fresh water prawn Macrobrachium rosenbergii: Purification from eyestalk nervous tissue and quantification by ELISA in hemolymph following various stresses. Aquaculture 286: 290-295.
Rout N., Citarasu T., Ravindran R. and Murugan V. 2005. Transcriptional and translational expression profile of a white spot syndrome viral (WSSV) gene in different organs of infected shrimp Aquaculture 245:31- 38.
Sahul Hameed A.S., Murthi B.L.M., Rasheed M., Sathish S., Yoganandhan K., Murugan V. and Kunthala Jayaraman. 2002. An investigation of Artemia as a possible vector for white spot syndrome virus WSSV transmission to Penaeus indicus. Aquaculture 204: 1-10.
Sánchez-Paz A. 2010. White spot syndrome virus: an overview on an emergent concern. Veterinary Research 41: 1-43.
Santos E.A., Nery L.E. M., Keller R. and Concalves A.A. 1997. Evidence for the involvement of the crustacean hyperglycemic hormone in the regulation of lipid metabolism. Physiological Zoology 70: 415-420.
Sarathi M., Nazeer Basha A., Ravi M., Venkatesan C., Senthil Kumar B., and Sahul Hameed A.S. 2008. Clearance of white spot syndrome virus (WSSV) and immunological changes in experimentally WSSV-injected Macrobrachium rosenbergii Fih & Shellfish Immunology 25: 222-230.
Sarojiji R., Nagabhushanam R. and Fingerman M. 1995. A neurotransmitter role for red-pigment-concentrating hormone in ovarian maturation in the red swamp crayfish Procambarus. The Journal of Experimental Biology 198: 1253-1257.
Sedlmeier D. and Keller R. 1981. The mode of action of the crustacean neurosecretory hyperglycemic hormone: Involvement of cyclic nucleotides. General and comparative endocrinology 45:82-90.
Serrano L., Blanvillain G., Soyez D., Charmantier G., Grousset E. Aujoulat F. and Spanings-Pierrot C. 2003. Putative involvement of crustacean hyperglycemic hormone isoforms in the neuroendocrine mediation of osmoregulation in the crayfish Astacus leptodactylus. Journal of Experimental Biology 206: 979-988.
Shi Z., WangH., Zhang J., Xie Y., Li L., Chen X., Edgerton B.F. and Bonami J.R. 2005. Response of crayfish, Procambarus clarkii, haemocytes infected by white spot syndrome virus. Journal of Fish Diseases 28: 151-156.
Smith V.J., Brown J.H. and Hauton C. 2003. Immunostimulation in crustaceans: does it really protect against infection? Fish Shellfish Immunol 15:71-90.
Smullen R.P., David J.A. and Pitman R.M. 1996. Endocrine regulation of the phosphatidylinositol pathway in the Norway lobster, Nephrops norvegicus, and the shore crab, Carcinus maenas. General and Comparative Endocrinology 104:84-91.
Söderhäll I., Bangyeekhun E., Mayo S. and Söderhäll K. 2003. Hemocyte production and maturation in an invertebrate animal: proliferation and gene expression in hematopoietic stem cells of Pacifastacus leniusculus. Developmental and Comparative Immunology 27: 661-672.
Söderhäll K. and Cerenius L. 1998. Role of the prophenoloxidase-activating system in invertebrate immunity. Current Opinion in Immunology 10:23-28.
Soyez D. 1997. Occurrence and diversity of neuropeptides from the crustacean hyperglycemic hormone family in arthropods. A short review. Annals of the New York Academy of Sciences 814:319-323.
Tiu S.H., He J.G. and Chan S.M. 2007. The LvCHH-ITP gene of the shrimp (Litopenaeus vannamei) produces a widely expressed putative ion transport peptide (LvITP) for osmo-regulation. Gene 396, 226-235.
Toullec J.Y., Vinh J., Le Caerb J.P., Shillito B. and Soyez D. 2002. Structure and phylogeny of the crustacean hyperglycemic hormone and its precursor from a hydrothermal vent crustacean: the crab Bythograea thermydron. Peptides 23: 31-42.
Tsai K.W., Chang S.J., Wu H.J., Shih H.Y., Chen C.H. and Lee C.Y. 2008. Molecular cloning and differential expression pattern of two structural variants of the crustacean hyperglycemic hormone family from the mud crab Scylla olivacea. General and Comparative Endocrinology 159:16-25.
Vargas-Albores F. and Yepiz-Plascencia G. 2000. Beta glucan binding protein and its role in shrimp immune response. Aquaculture 191:12-21.
Wainwright G., Webster S.G., Wilkinson M.C., Chung J.S. and Rees H.H. 1996. Structure and significance of mandibular organ-inhibiting hormone in the crab, Cancer pagurus. Involvement in multihormonal regulation of growth and reproduction. The Journal of Biological Chemistry 271: 12749-12754.
Wang C.H., Lo C.F., Leu J.H., Chou C.M., Yeh P.Y., Chou H.Y., Tung M.E., Chang C.F., Su M.S. and Kou G.H. 1995. Purification and genomic analysis of baculovirus associated with white spot syndrome (WSBV) of Penaeus monodon. Diseases of Aquatic Organisms 23: 239-242.
Wang Y.C., Lo C.F., Chang P.S. and Kou G.H. 1998. Experimental infection of white spot baculovirus in some cultured and wild decapods in Taiwan. Aquaculture 164:221-231.
Webster S.G., Dircksen H. and Chung J.S. 2000. Endocrine cells in the gut of the shore crab Carcinus maenas immunoreactive to crustacean hyperglycemic hormone and its precursor-related peptide. Cell and Tissue Research 300: 193-205.
Wiwegweaw A., Udomkit A. and Panyim S. 2004. Molecular structure and organization of crustacean hyperglycemic hormone genes of Penaeus monodon. Journal of Biochemistry and Molecular Biology 37: 177-184.
Yan D.C., Feng S.Y., Huang J. and Dong S.L. 2007. Rotifer cellular membranes bind to white spot syndrome virus (WSSV) Aquaculture 273: 423-426.
Yasuda A., Yasuda Y., Fujita T. and Naya Y. 1994. Characterization of crustacean hyperglycemic hormone from the crayfish (Procambarus clarkii) : multiplicity of molecular forms by stereo inversion and diverse functions. General and Comparative Endocrinology 95: 387-398.
Yang W.J., Aida K. and Nagasawa H. 1997. Amino acid sequences and activities of multiple hyperglycemic hormones from the Kuruma prawn, Penaeus japonicus. Peptides 18:479-485.
Yoganandhan k., Thirupathi S. and Sahul Hameed A.S. 2003. Biochemical, physiological and hematological changes in white spot syndrome virus-infected shrimp, Penaeus indicus. Aquaculture 221: 1-11.
Yoganandhan k., Sathish S., Murugan V., Narayanan R.B. and Sahul Hameed A.S. 2003. Screening the organs for early detection of white spot syndrome virus in Penaeus indicus by histopathology and PCR techniques. Aquaculture 215 : 21-29.
YongZeng and Lu C.P. 2009 Identification of differentially expressed genes in haemocytes of the crayfish (Procambarus clarkii) infected with white spot syndrome virus by suppression subtractive hybridization and cDNA microarrays Fish and Shellfish Immunology 26: 646-650.
Zhang J.S., Dong S.L., DongY.W., Tian X.L. and Hou C.Q. 2008. Bioassay evidence for the transmission of WSSV by the harpacticoid copepod Nitocra sp. Journal of Invertebrate Pathology 97:33-39.
Zhi F.Z., Shao M.Y. and Kang K.H. 2005 Changes of enzyme activity and hematopoiesis in Chinese prawn Fenneropenaeus chinensis (Osbeck) induced by white spot syndrome virus and zymosan A. Aquaculture Research 36: 674-681.
Zou H.S., Juan C.C., Chen S.C., Wang H.Y. and Lee C.Y. 2003. Dopaminergic regulation of crustacean hyperglycemic hormone and glucose levels in the hemolymph of the crayfish Procambarus clarkii. Journal of experimental zoology 298:44-52.

連結至畢業學校之論文網頁點我開啟連結
註: 此連結為研究生畢業學校所提供,不一定有電子全文可供下載,若連結有誤,請點選上方之〝勘誤回報〞功能,我們會盡快修正,謝謝!
QRCODE
 
 
 
 
 
                                                                                                                                                                                                                                                                                                                                                                                                               
第一頁 上一頁 下一頁 最後一頁 top
系統版面圖檔 系統版面圖檔