我們發展的偏振影像所產生的Stokes vector ( I ,Q ,U ,V )可以提供獨立的四個訊號來表示在通過樣本之後光波的線偏振與圓偏振情形。經過我們的理論推導後，可以得到物質Mueller matrix的多個訊號特徵。利用這些訊號特徵，我們能夠套用已發展的理論模型來分析並解釋光在物質裡面產生的變化，這個Mueller matrix 影像系統可以提供獨立的光學參數來檢測生醫組織的結構改變，並且可望能夠應用在生醫領域以及臨床的腫瘤組織判別上。

Polarimetric imaging of Stokes vector (I, Q, U, V) can provide 4 independent signatures showing the linear and circular polarization properties of samples of interest including biological tissues and cells. Using a Stokes digital imaging system, we measured the Stokes vector images of tissue samples from sections of rat livers. The derived Mueller matrix elements can quantitatively provide five-signature spectral imaging data of the bio-samples. The imaging of four independent optical properties: anisotropy, scattering, depolarization and retardation phase of the test sample are derived and reported. Our experimental results are consistent with the general trend predicted by the theoretical model. This polarimetric multi-signature optical technology is a new option of bio-sensing technology to inspect the structures of tissue samples and is potentially useful for critical disease discrimination and medical diagnostics applications.

-致謝- i
-摘要- ii
-Abstract- iii
-目錄- iv
Chapter 1 Introduction 5
1.1 History and applications of polarized light 5
1.2 Motivation 7
Chapter 2 Basic theory 9
2.1 Theory of optical polarization 9
2.2 Polarization state representation 13
2.2.1 Jones vector and Jones matrix 13
2.2.2 Stokes vector & Mueller matrix 14
2.2.3 Ellipsometric parameters 16
2.3 Mueller matrix elements 17
Chapter 3 Experiments 20
3.1 Experimental materials 20
3.1.1 Liquid crystal 20
3.1.2 Intravenous fat emulsion 21
3.1.3 Histopathology 22
3.2 Experimental setup 23
3.3 Experimental Method 25
3.3.1 System validation and measurement test 25
3.3.2 Biopsy measurement 25
Chapter 4 Experimental results and discussion 27
4.1 Experimental validation 27
4.2 Bio-materials testing 32
Chapter 5 Conclusion and future work 40
Reference 42
Appendix A A-1
Appendix B B-1

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