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研究生:陳惠真
論文名稱:台灣土當歸精油組成、機能性成分分析及其抗氧化能力評估
指導教授:林麗雲博士
學位類別:碩士
校院名稱:弘光科技大學
系所名稱:生物產業研究所
學門:農業科學學門
學類:農業經濟及推廣學類
論文種類:學術論文
畢業學年度:99
語文別:中文
論文頁數:104
中文關鍵詞:台灣土當歸精油抗氧化能力機能性成分
外文關鍵詞:Angelica acutilobaessential oilantioxidative activityfunctional constituent
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台灣土當歸(Angelica acutiloba)為繖形科植物(Apiaceae)之當歸屬(Angelica L.),係多年生草本植物,全草均可食用。在傳統上當歸多是利用根部當作藥材使用,用以補血、和血、調經止血及潤腸通便。中國有多位學者針對大陸產當歸根部進行不同揮發油提取方法及化學成分分析,但對當歸各部位並無相關文獻報導。因此,本研究擬對台灣產當歸進行整株植物不同部位進行一般成分、精油成分及機能性成分分析及討論抗氧化能力。
研究結果如下:台灣土當歸各部位精油收率為:根0.4%、莖0.48%、葉0.18%;於土當歸根部精油共鑑定出103個化合物,莖部69個化合物,葉部則為87個化合物。不同部位精油主要成分為3-n-butylphthalide、γ-terpinene、p-cymene及cis-ocimene。於土當歸機能性成分分析中,在膳食纖維方面,葉、莖及根部含量依序分別為56.47%、50.70%及37.37%,但在水溶性纖維含量方面則根、葉及莖部分別佔膳食纖維含量的17%、10%及11%。有機酸方面,根及莖部不含草酸(oxalic acid)成分,而葉中則含4.05mg/100g;根、莖、葉之酒石酸(tartaric acid)含量分別為每100g樣品含166.82mg、214.94mg及29.01mg,蘋果酸(malic acid)含量分別為每100g樣品含3.4mg、25.04mg及34.61mg,檸檬酸(citric acid)含量分別為每100g樣品含2.33mg、6.38mg及22.09mg,而琥珀酸(succinic acid)含量分別為每100g樣品含3.86mg、3.59mg及1.74mg。在核苷酸含量,只測定到尿苷酸(5’-UMP),根、莖、葉含量分別為每100g含61.34mg、184.49mg及182.89mg。不同部位中根部含有較多量的蔗糖,約每100g乾燥根部含有30.08g蔗糖,葉含12.56g,而莖部則不含醣類。檞皮素(quercetin)含量以葉部最多,而莖及根部相近,依序為1.20mg/100g及0.70mg/100g。芸香苷(rutin)含量分別為葉、莖及根,每100g樣品含:11.35mg、1.72mg及0.80mg。總酚含量水萃取物方面依序為葉、莖及根部每100g樣品含:403.59mg、144.03mg及116.97mg,乙醇萃取物方面依序為葉、莖及根部每100g樣品含870.50mg、255.29mg及146.30mg。阿魏酸成分只在根部中分析到,以5%甲酸甲醇萃取測定阿魏酸含量,在直接乾燥樣品中測得之阿魏酸含量為0.23%,另外以水萃物及乙醇萃取物樣品中測得之阿魏酸含量則相近,只有0.1%。抗氧化能力方面,無論在清除DPPH自由基能力、螯合亞鐵離子能力、總抗氧化能力及還原力等測定方法中均發現其有相當的活性,以部位而言,葉子的抗氧化能力最好、其次為莖、而根部最低,另外各部位水的萃取物抗氧化能力都比乙醇萃取物為佳,在各部位芸香苷、檞皮素與總酚含量以葉部較高,而其在抗氧化能力活性也較強。
Angelica acutiloba belongs to the Apiaceae family and Angelica L.genus, which is a perennial herbaceous plant. People use usually it’s rhizome as a traditional medicine for the producing blood, modulating menstruation, hemostasis and treating constipation. But few studies have
been published on the different parts of Angelica acutiloba. In our study, we analyze the general compositions, essential oil, functional constituents and
antioxidative activity in the different parts of Angelica acutiloba.
The results are as follows the yields of essential oil from , rhizome, steam and leaf are 0.4!, 0.48!and 0.18!, respectively. The numbers of identified compounds are 103, 69 and 87 in essential oil from rhizomes, stems and leaves, respectively, and the major compounds are 3-n-butylphthalide, -terpinene, p-cymene and cis-ocimene. The contents of dietary fiber of leaves,stems and rhizomes are 56.47!, 50.70! and 37.37!, respectively, and the percentage of soluble fiber in the dietary fiber is 10!, 11! and 17!, respectively. In the assessment of organic acid: the
rhizomes and stems don’t have oxalic acid component, but the contents of oxalic acid are 4.05mg per 100g leaves; the contents of tartaric acid in the rhizomes, stems and leaves are per 100g samples including 166.82mg, 214.94mg and 29.01mg , respectively"the contents of malic aicd are per
100g samples including 3.4mg, 25.04mg and 34.61mg , respectively; the contents of citric acid are per 100g samples including 2.33mg, 6.38mg and 22.09mg , respectively; and the contents of succinic acid are 3.86mg,
3.59mg and 1.74mg per 100g samples, respectively. It is only finding the 5’-UMP component in the analysis of nucleotide components and the contents of rhizomes, stems, leaves are per 61.34mg, 184.49mg and 182.89mg per 100g samples, respectively. There are contain the most amounts of sucrose about 30.08g per 100g rhizomes. The leaves contain12.56g sucrose per 100g samples, and no finding is noted in the stems. The leaves contain the most amounts of quercetin about 1.20mg per 100g samples, and the contents are almost to be equal in the stems and rhizomes
about 0.7mg per 100g samples. The contents of rutin in the leaves, stems and rhizomes are per 100g samples including 11.35mg, 1.72mg and 0.80mg, respectively. The contents of total phenol of water extracts in the leaves, stem and rhizome are per 100g including 403.59, 144.03mg and 116.97mg, respectively, and the total phenol contents of ethanol extract are per 100g samples including 870.50mg, 255.29mg and 146.30mg, respectively. The ferulic acid components exist only in the rhizomes. The contents of ferulic acid from rhizomes are 0.23! and there are similar ferulic acid contents between the water and ethanol extracts to be about 0.1!. The leaves have the best antioxidative capacity, followed by stems, while the rhizomes are lowest in all the types of antioxidative tests about the DPPH scavenging capability, the chelating effect of ferrous ions, the total antioxidative capacity and reducing capacity. Every type of antioxidative capacities of the water extractions are better than ethanol extracts. Having a consistency between the quantities of rutin, quertin and total phenol compound and the antioxidative capacity.
目錄...i
表目次...iii
圖目次...iv
中文摘要...v
Abstract...vii
一.前言...1
二.文獻回顧...2
2.1台灣土當歸簡介...2
2.1.1型態分部...2
2.1.2化學成分...3
2.1.3藥理作用...5
2.2精油化學成分...8
2.3萜烯類化合物...10
2.4精油的萃取方法...17
2.5抗氧化的能力分析...19
2.5.1自由基的作用...19
2.5.2抗氧化劑簡介...22
2.5.3抗氧化能力分析測定...33
三.材料與方法...40
3.1實驗架構...40
3.2一般成分與機能性成份分析...41
3.2.1實驗材料...41
3.2.2實驗藥材...41
3.2.3實驗器材...41
3.2.4實驗方法...41
3.3當歸不同部位抗氧化之研究...48
3.3.1實驗材料...48
3.3.2實驗藥材...48
3.3.3實驗器材...48
3.3.4實驗方法...48
四.結果與討論...50
4.1台灣土當歸各部位樣品之一般成分分析...50
4.2台灣土當歸各部位樣品精油收率...51
4.3台灣土當歸各部位樣品精油揮發性成分含量分析...52
4.4台灣土當歸各部位樣品水萃物與乙醇萃取物萃取率...72
4.5台灣土當歸各部位樣品可溶性醣類分析...73
4.6台灣土當歸各部位樣品有機酸含量分析...74
4.7台灣土當歸各部位樣品核苷酸含量分析...75
4.8台灣土當歸各部位樣品膳食纖維含量分析...76
4.9台灣土當歸各部位樣品槲皮素與芸香苷含量分析...77
4.10台灣土當歸各部位樣品水萃物及乙醇萃取物總酚含量分析...78
4.11台灣土當歸各部位樣品水萃物及乙醇萃取物阿魏酸含量分析...79
4.12清除1,1-disphenyl-2-picryl-hydrazyl(DPPH.)自由基能力...81
4.13螯合亞鐵離子能力分析...84
4.14總抗氧化能力(Total antioxidant capacity)分析...87
4.15還原力FRAP (ferric reducing antioxidant power)分析...88
五.結論...90
六.參考文獻...92


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