CHAPTER 1 INTRODUCTION 1 1.1 Motivation 1 1.2 Background and Related Works 3 1.3 Thesis Organization and System Flow Chart 7 CHAPTER 2 EXPERIMENT DESCRIPTION AND DATA ACQUISITION 11 2.1 Experiment Description 11 2.1.1 Experiment Environment 11 2.1.2 Subjects and Stimuli Events 13 2.2 Data Acquisition 15 CHAPTER 3 FMRI ANALYSIS 16 3.1 Overview 16 3.2 fMRI Preprocessing 16 3.2.1 Realignment 16 3.2.2 Segmentation 18 3.2.3 Normalization 19 3.2.4 Smoothing 21 3.3 Significant Region Estimation 22 CHAPTER 4 EEG BRAIN MAPPING 24 4.1 Overview 24 4.2 Coordinates Integration 24 4.3 Linear Interpolation 28 CHAPTER 5 EEG PREPROCESSING 30 5.1 Overview 30 5.2 Processing Steps 31 CHAPTER 6 EVENT-RELATED 37 DESYNCHRONIZATION (ERD) VERIFICATION 37 6.1 Overview 37 6.2 Processing Steps 38 CHAPTER 7 GRANGER CAUSALITY MODEL (GCM) 40 7.1 Overview 40 7.2 Algorithm 41 7.3 Parameter Training 43 7.4 Frequency Band Selection 47 CHAPTER 8 EXPERIMENTAL RESULTS AND DISCUSSION 49 8.1 Overview 49 8.2 Activated ROI Results from fMRI Data 50 8.3 De-correlation Processing Verification 61 8.4 GCM Results and Comparisons from EEG Data 62 8.4.1 Overview 63 8.4.2 Intra-subject multi-points crossover analysis of one event 64 8.4.3 Regional Sensitivity Test 87 CHAPTER 9 CONCLUSIONS AND FUTURE WORKS 90 REFERENCES 93 VITA 96
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