中文摘要 I ABSTRACT II 致謝 III List of Tables VI List of Figures VII Chapter 1 Introduction 1 1.1 Bioimpedance 1 1.2 Blood Flow Impedance Characterization 2 1.3 Effect of Temperature on Bioimpedance Measurement 6 1.4 Temperature Compensation 7 1.4.1 Temperature Correction Factor 8 1.4.2 Control of Ambient Temperature 10 1.5 Electrode Design 11 1.5.1 Varying Spacing Distance 11 1.5.2 Varying Disc area 11 1.6 Target Application 12 1.7 Motivation and purposes 13 Chapter 2 Materials and Methods 14 2.1 The research overview 14 2.2 Hardware Design 15 2.2.1 MCU 15 2.2.2 Impedance Measurement Circuit 16 2.2.3 Temperature Monitoring Circuit 21 2.2.4 Electrode Design and Position 22 2.2.5 Electrode Spacing Distance Simulation 23 2.3 Software Design 25 2.3.1 System Control Program 25 2.3.2 GUI 27 2.3.3 Demodulation Algorithm 29 Chapter 3 Results and Discussions 32 3.1 Bioimpedance Measuring System 32 3.1.1 Modular Circuit Design 33 3.2 The operational functions of developed system 35 3.3 The evaluation of developed system 37 3.3.1 Total harmonic distortion 37 3.3.2 Output impedance 40 3.3.3 Current out stability 42 3.3.4 The measurement error test 43 3.4 The decade resistor measurement 45 3.5 Temperature-Impedance calibration curve 47 3.6 COMSOL simulation 49 3.7 PORK test 54 3.8 GEL test 55 3.9 LDF and Bioimpedance system experiment 55 Chapter 4 Conclusions and Prospects 60 4.1 Conclusions 60 4.2 Prospects 61 References 62
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