|
1. Barnes, C.A. (1979). Memory deficits associated with senescence: a neurophysiological and behavioral study in the rat. J. Comp. Physiol. Psychol. 93, 74–104. 2. Basselin, M., Chang, L., Chen, M., Bell, J.M., and Rapoport, S.I. (2008). Chronic administration of valproic acid reduces brain NMDA signaling via arachidonic acid in unanesthetized rats. Neurochem Res 33, 2229-2240. 3. Baynes, W.J. (2001). The role of AGEs in aging: causation or correlation. Expt. Geront. 36, 1527–1537. 4. Burton, G.W., and Ingold, K.U. (1984). beta-Carotene: an unusual type of lipid antioxidant. Science 224, 569-573. 5. Butterfield, D.A., and Lauderback, C.M. (2002). Lipid peroxidation and protein oxidation in Alzheimers disease brain: potential causes and consequences involving amyloid beta-peptide-associated free radical oxidative stress. Free Radic Biol Med 32, 1050-1060. 6. Calleja, M., Pena, P., Ugalde, C., Ferreiro, C., Marco, R., and Garesse, R. (1993). Mitochondrial DNA remains intact during Drosophila aging, but the levels of mitochondrial transcripts are significantly reduced. J Biol Chem 268, 18891-18897. 7. Cameron, E., and Pauling, L. (1976). Supplemental ascorbate in the supportive treatment of cancer: Prolongation of survival times in terminal human cancer. Proc Natl Acad Sci U S A 73, 3685-3689. 8. Carr, A., and Frei, B. (1999). Does vitamin C act as a pro-oxidant under physiological conditions? FASEB J 13, 1007-1024. 9. Cecchi, C., Latorraca, S., Sorbi, S., Iantomasi, T., Favilli, F., Vincenzini, M.T., and Liguri, G. (1999). Gluthatione level is altered in lymphoblasts from patients with familial Alzheimers disease. Neurosci Lett 275, 152-154. 10. Choi, S.H., Aid, S., and Bosetti, F. (2009). The distinct roles of cyclooxygenase-1 and -2 in neuroinflammation: implications for translational research. Trends Pharmacol Sci 30, 174-181. 11. Cui, X., Zuo, P., Zhang, Q., Li, X., Hu, Y., Long, J., Packer, L., and Liu, J. (2006). Chronic systemic D-galactose exposure induces memory loss, neurodegeneration, and oxidative damage in mice: protective effects of R-alpha-lipoic acid. J Neurosci Res 84, 647-654. 12. Culmsee, C., and Krieglstein, J. (2007). Ischaemic brain damage after stroke: new insights into efficient therapeutic strategies. International Symposium on Neurodegeneration and Neuroprotection. EMBO Rep 8, 129-133. 13. Cruz, T., Galvez, J., Ocete, M.A., Crespo, M.E., Sanchez de Medina LHF., and Zarzuelo, A. (1998). Oral administration of rutoside can ameliorate inflammatory bowel disease in rats. Life Sci 62, 687–695. 14. Del Rio, P., Montiel, T., Chagoya, V., and Massieu, L. (2007). Exacerbation of excitotoxic neuronal death induced during mitochondrial inhibition in vivo: relation to energy imbalance or ATP depletion? Neuroscience 146, 1561-1570. 15. Emerit, J., Edeas, M., and Bricaire, F. (2004). Neurodegenerative diseases and oxidative stress. Biomed Pharmacother 58, 39-46. 16. Feng, L., Xia, Y., Garcia, G.E., Hwang, D., and Wilson, C.B. (1995). Involvement of reactive oxygen intermediates in cyclooxygenase-2 expression induced by interleukin-1, tumor necrosis factor-alpha, and lipopolysaccharide. J Clin Invest 95, 1669-1675. 17. Finkel, T., and Holbrook, N.J. (2000). Oxidants, oxidative stress and the biology of ageing. Nature 408, 239-247. 18. Flanary, B.E., and Streit, W.J. (2006). Alpha-tocopherol (vitamin E) induces rapid, nonsustained proliferation in cultured rat microglia. Glia 53, 669-674. 19. Floyd, R., and Hensley, K., (2002). Oxidative stress in brain aging implications for therapeutics of neurodegenerative diseases. Neurobiol. Aging 23, 795–807. 20. Guardia, T., Rotelli, A.E., Juarez, A.O., and Pelzer, L.E. (2001). Anti-inflammatory properties of plant flavonoids. Effects of rutin, quercetin and hesperidin on adjuvant arthritis in rat. Farmaco 56,683-687. 21. Gupta, R., Singh, M., and Sharma, A. (2003). Neuroprotective effect of antioxidants on ischaemia and reperfusion-induced cerebral injury. Pharmacol Res 48,209-215. 22. Gustafsson, A.B., Sayen, M.R., Williams, S.D., Crow, M.T., and Gottlieb, R.A. (2002). TAT protein transduction into isolated perfused hearts: TAT-apoptosis repressor with caspase recruitment domain is cardioprotective. Circulation 106, 735-739. 23. Harman, D. (1956). Aging: a theory based on free radical and radiation chemistry. J Gerontol 11, 298-300. 24. Hensley, K., Carney, J.M., Mattson, M.P., Aksenova, M., Harris, M., Wu, J.F., Floyd, R.A., and Butterfield, D.A. (1994). A model for beta-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: relevance to Alzheimer disease. Proc Natl Acad Sci U S A 91, 3270-3274. 25. Hewett, S.J., Uliasz, T.F., Vidwans, A.S., and Hewett, J.A. (2000). Cyclooxygenase-2 contributes to N-methyl-D-aspartate-mediated neuronal cell death in primary cortical cell culture. J Pharmacol Exp Ther 293, 417-425. 26. Hsieh, H., Wua, W., and Hu, M. (2009). Soy isoflavones attenuate oxidative stress and improve parameters related to aging and Alzheimer’s disease in C57BL/6J mice treated with D-galactose. Food Chem. Toxicol. 47, 625–632. 27. Hunsaker, M.R., Lee, B., and Kesner, R.P. (2008). Evaluating the temporal context of episodic memory: the role of CA3 and CA1. Behav Brain Res 188:310–315. 28. Im, J.Y., Kim, D., Paik, S.G., and Han, P.L. (2006). Cyclooxygenase-2-dependent neuronal death proceeds via superoxide anion generation. Free Radic Biol Med 41, 960-972. 29. Ikawa, H., Kameda, H., Kamitani, H., Baek, S.J., Nixon, J.B., Hsi, L.C., and Eling, T.E. (2001). Effect of PPAR activators on cytokine-stimulated cyclooxygenase-2 expression in human colorectal carcinoma cells. Exp Cell Res 267, 73-80. 30. Jang, Y.C., and Remmen, H.V. (2009). The mitochondrial theory of aging: insight from transgenic and knockout mouse models. Exp. Gerontol. 44, 256–260. 31. Jones, D.P., Carlson, J.L., Mody, V.C., Cai, J., Lynn, M.J., and Sternberg, P. (2000). Redox state of glutathione in human plasma. Free Radic Biol Med 28, 625-635. 32. Kaplan, L.A., and Pesce, A.J. (1996). Clinical Chemistry, third ed. Mosby, St. Louis. p. 954. 33. Kim, H., Kong, H., Choi, B., Yang, Y., Kim, Y., Lim, M.J., Neckers, L., and Jung, Y. (2005). Metabolic and pharmacological properties of rutin, a dietary quercetin glycoside, for treatment of inflammatory bowel disease. Pharm Res 22:1499–1509. 34. Kukreja, R.C., Kontos, H.A., Hess, M.L., and Ellis, E.F. (1986). PGH synthase and lipoxygenase generate superoxide in the presence of NADH or NADPH. Circ Res 59, 612-619. 35. Lu, J., Xing, J., and Li, J. (2007). Prostaglandin E2 (PGE2) inhibits glutamatergic synaptic transmission in dorsolateral periaqueductal gray (dl-PAG). Brain Res 1162, 38-47. 36. Masella, R., Di Benedetto, R., Vari, R., Filesi, C., and Giovannini, C. (2005). Novel mechanisms of natural antioxidant compounds in biological systems: involvement of glutathione and glutathione-related enzymes. J Nutr Biochem 16, 577-586. 37. Morris, R.G., Garrud, P., Rawlins, J.N., and O’Keefe, J. (1982). Place navigation impaired in rats with hippocampal lesions. Nature 297:681–683. 38. McCarty, M.F. (2006). Toward prevention of Alzheimers disease--potential nutraceutical strategies for suppressing the production of amyloid beta peptides. Med Hypotheses 67, 682-697. 39. McCord, J.M., and Fridovich, I. (1969). Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein). J Biol Chem 244, 6049-6055. 40. Miettinen, S., Fusco, F.R., Yrjanheikki, J., Keinanen, R., Hirvonen, T., Miller, D.M., Buettner, G.R., and Aust, S.D. (1990). Transition metals as catalysts of "autoxidation" reactions. Free Radic Biol Med 8, 95-108. 41. Miquel, J., Economos, A.C., Fleming, J., and Johnson, Jr., J.E. (1980). Mitochondrial role in cell aging. Exp. Gerontol. 15, 575-591. 42. Nakamura, T., and Sakamoto, K. (2001). Reactive oxygen species up-regulates cyclooxygenase-2, p53, and Bax mRNA expression in bovine luteal cells. Biochem Biophys Res Commun 284, 203-210. 43. Nogueira, C.W., Zeni, G., and Rocha, J.B. (2004). Organoselenium and organotellurium compounds: toxicology and pharmacology. Chem Rev 104, 6255-6285. 44. Richetti, S.K., Blank, M., Capiotti, K.M., Piato A.L., Bogo, M.R., Vianna, M.R., and Bonan, C.D. (2011). Quercetin and rutin prevent scopolamine-induced memory impairment in zebrafish. Behav Brain Res 217, 10-5. 45. Rockwell, P., Martinez, J., Papa, L., and Gomes, E. (2004). Redox regulates COX-2 upregulation and cell death in the neuronal response to cadmium. Cell Signal 16, 343-353. 46. Rosenzweig, E.S., and Barnes, C.A. (2003). Impact of aging on hippocampal function: plasticity, network dynamics, and cognition. Prog. Neurobiol. 69, 143-179. 47. Ryter, S.W., and Tyrrell, R.M. (1998). Singlet molecular oxygen ((1)O2): a possible effector of eukaryotic gene expression. Free Radic Biol Med 24, 1520-1534. 48. Sanzgiri, R.P., Araque, A., and Haydon, P.G. (1999). Prostaglandin E(2) stimulates glutamate receptor-dependent astrocyte neuromodulation in cultured hippocampal cells. J Neurobiol 41, 221-229. 49. Shen, D., Dalton, T.P., Nebert, D.W., and Shertzer, H.G. (2005). Glutathione redox state regulates mitochondrial reactive oxygen production. J Biol Chem 280, 25305-25312. 50. Shim, M., and Eling, T.E. (2008). Vitamin E succinate induces NAG-1 expression in a p38 kinase-dependent mechanism. Mol Cancer Ther 7, 961-971. 51. Song, X., Bao, M., Li, D., and Li, Y. (1999). Advanced glycation in D-galactose induced mouse aging model. Mech. Ageing Dev. 108, 239–251. 52. Stella, N., Tence, M., Glowinski, J., and Premont, J. (1994). Glutamate-evoked release of arachidonic acid from mouse brain astrocytes. J Neurosci 14, 568-575. 53. Suh, J.H., Moreau, R., Heath, S.H., and Hagen, T.M. (2005). Dietary supplementation with (R)-alpha-lipoic acid reverses the age-related accumulation of iron and depletion of antioxidants in the rat cerebral cortex. Redox Rep 10, 52-60. 54. Taylor, A.L., and Hewett, S.J. (2002). Potassium-evoked glutamate release liberates arachidonic acid from cortical neurons. J Biol Chem 277, 43881-43887. 55. Tomoko, K., Yoshiki, K., and Hideki, I. (2008). Protective effect of rutin against spatial memory impairment induced by trimethyltin in rats. Nutrition Research 28,629-634. 56. Tzeng, S.F., Hsiao, H.Y., and Mak, O.T. (2005). Prostaglandins and cyclooxygenases in glial cells during brain inflammation. Curr Drug Targets Inflamm Allergy 4, 335-340. 57. Valko, M., Leibfritz, D., Moncol, J., Cronin, M.T., Mazur, M., and Telser, J. (2007). Free radicals and antioxidants in normal physiological functions and human disease. Int J Biochem Cell Biol 39, 44-84. 58. Valko, M., Morris, H., and Cronin, M.T. (2005). Metals, toxicity and oxidative stress. Curr Med Chem 12, 1161-1208. 59. Valko, M., Rhodes, C.J., Moncol, J., Izakovic, M., and Mazur, M. (2006). Free radicals, metals and antioxidants in oxidative stress-induced cancer. Chem Biol Interact 160, 1-40. 60. Wang, Q., Tang, X.N., and Yenari, M.A. (2007). The inflammatory response in stroke. J Neuroimmunol 184, 53-68. 61. Way, T.D., Lee, J.C., Kuo, D.H., Fan, L.L., Huang, C.H., Lin, H.Y., Shieh, P.C., Kuo, P.T., Liao, C.F., Liu, H., and Kao, J.Y. (2010) Inhibition of epidermal growth factor receptor signaling by Saussurea involucrata, a rare traditional Chinese medicinal herb, in human hormone-resistant prostate cancer PC-3 cells. J Agric Food Chem 58, 3356–3365. 62. Yang, H., and Chen, C. (2008). Cyclooxygenase-2 in synaptic signaling. Curr Pharm Des 14, 1443-1451.
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