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研究生:林耀駿
研究生(外文):Yao-Chun Lin
論文名稱:不同頻率電針刺激微循環血流效應之研究
論文名稱(外文):Study on microcirculatory effect by electro-acupuncture stimulation with different frequencies
指導教授:陳永盛陳永盛引用關係
指導教授(外文):Yung-Sheng Chen
學位類別:碩士
校院名稱:元智大學
系所名稱:電機工程學系
學門:工程學門
學類:電資工程學類
論文種類:學術論文
論文出版年:2011
畢業學年度:99
語文別:中文
論文頁數:43
中文關鍵詞:雷射都卜勒血流計、電針、低頻刺激、微循環
外文關鍵詞:laser doppler flowmetry, electro-acupuncture, low frequency stimulation, microcirculation
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微循環是人體循環最基礎且最重要的部份,穴道、血管的叢集處更是分析血流特性的關鍵點。人體健康與微循環有著密不可分的關聯性,因此改善局部微循環供血在疾病早期治療改善上具有重大意義。本研究希望透過電針刺激這種微侵入的刺激方式,應用共振理論,試圖從心跳倍頻這種刺激模式改善微循環,並配合非侵入性儀器:雷射都卜勒血流計、心電圖對微循環平均血流量及血流波形作初步分析。
本實驗以不同頻率刺激左手的合谷穴及曲池穴,分別為(A)心跳的1倍頻(B)心跳的1.5倍頻,並觀察刺激前後的反應。經由分析結果,電針刺激對於局部血流參數的效應上皆有改善,而且可能可提高心臟的工作效率;但是在微循環變異率上則呈現兩種不同的趨勢,1倍頻上升,1.5倍頻下降。這可能是因為1倍頻刺激比較接近心跳頻率,心臟比較容易運用1倍頻刺激,並且利用這個力量傳達到局部未接受刺激的部位,而1.5倍頻刺激則較無法讓心臟容易運用,這也可能使得1.5倍頻的心跳變異率接近顯著上升。中醫認為低頻刺激為補的效應,即使同樣是低頻刺激,效應上還是有不同處,對於電刺激等各種改善供血的方式,未來將可以運用心跳倍頻這個特點達到增進或抑制局部血流供應,在臨床診療或研究上,也可以此為基礎,提供一個客觀評估療效與生理機制探討的研究模型。


Microcirculation is the most basic and important part of the human body. Acupoints and vessels are the key points for analyzing the characteristics of blood flow. There exists a close relation between health and microcirculation so that improving blood supply has significant meaning on treating early time disease. This research wishes to improve the function of microcirculation by electro-acupuncture, applying resonance theorem and noninvasive instruments to analyze mean blood flux and blood flow wave base on times of heart rate.
In this experiment, we stimulate on volunteers'' left Hegu and Quchi by different frequencies: (a) one time of heart rate (b) one point five times of heart rate, and observe the effect after the stimulation. From the result, electro-acupuncture stimulation can both improve the effect and may increase the efficiency of heart working. But we notice that the variability on microcirculation are difference, increase on (a) and decrease on (b). This is possibly that (a) is more close volunteers'' heart rate, heart can use the stimulation easily and deliver this effect to other local sites. While (b) doesn''t, and make heart rate variability increased. Chinese medicine thinks LFS (low frequency stimulation) is supply, though (a) and (b) are both LFS, but the effect are not same. For stimulations to improve microcirculation, like electro-acupuncture, we can use this characteristic, times of heart rate to increase or decrease local blood supply. For clinical treatment and research, we can base on this characteristic to offer a study model for objective estimate the curative effect and investigate physiologic mechanism.


目錄
書名頁 ……………………………………………………………………… i
中文摘要 …………………………………………………………………… ii
Abstract …………………………………………………………………… iii
誌謝 …………………………………………………………………………… iv
目錄 ……………………………………………………………………………… v
表目錄 ……………………………………………………………………… vii
圖目錄 ……………………………………………………………………… viii
第一章 緒論 ……………………………………………………………………… 1
1.1 研究背景 ………………………………………………………………… 1
1.2 研究動機及目的 ………………………………………………………… 2
1.3 論文架構 ………………………………………………………………… 3
第二章 實驗設計 ………………………………………………………………… 4
2.1 儀器介紹 ………………………………………………………………… 4
2.1.1 雷射都卜勒血流計(Laser Doppler Flowmetry) …………………… 4
2.1.2 生理訊號放大器 …………………………………………………… 6
2.1.3 針灸針 ……………………………………………………………… 7
2.1.4 中頻電刺激器 ……………………………………………………… 8
2.1.5 訊號連接轉換器 ………………………………………………… 10
2.1.6 電子血壓計 ……………………………………………………… 11
2.2 實驗流程 ……………………………………………………………… 12
2.3 分析方法 ……………………………………………………………… 16
2.3.1 分析過程 ………………………………………………………… 16
第三章 實驗結果 ……………………………………………………………… 18
3.1 參數介紹及定義方式 ………………………………………………… 18
3.2 實驗數據 ……………………………………………………………… 23
3.2.1 兩組實驗之收縮壓、舒張壓、平均壓、心跳速率統計 ……… 24
3.2.2 兩組實驗之手部溫度、環境室溫統計 ………………………… 25
3.2.3 兩組實驗之DCflux統計 ………………………………………… 26
3.2.4 兩組實驗之CONC統計 ………………………………………… 26
3.2.5 兩組實驗之BV統計 …………………………………………… 27
3.2.6 兩組實驗之ACflux統計 ………………………………………… 27
3.2.7 兩組實驗之AD統計 …………………………………………… 28
3.2.8 兩組實驗之PW統計 …………………………………………… 28
3.2.9 兩組實驗之FDT統計 ………………………………………… 29
3.2.10兩組實驗之FRT統計 ………………………………………… 29
3.2.11兩組實驗之DCflux_CV統計 ………………………………… 30
3.2.12兩組實驗之CONC_CV統計 ………………………………… 30
3.2.13兩組實驗之BV_CV統計 ……………………………………… 31
3.2.14兩組實驗之ACflux_CV統計 ………………………………… 31
3.2.15兩組實驗之AD_CV統計 ……………………………………… 32
3.2.16兩組實驗之PW_CV統計 ……………………………………… 32
3.2.17兩組實驗之AMP_CV統計 …………………………………… 33
3.2.18兩組實驗之HR_CV和RR_CV統計 ………………………… 34
第四章 結果討論 ………………………………………………………………… 35
4.1 參數結果 ………………………………………………………………… 35
4.2 結論 ……………………………………………………………………… 38
4.3 未來展望 ………………………………………………………………… 40
參考文獻…………………………………………………………………………… 41


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