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研究生:江瑞錦
研究生(外文):Jui-ChinChiang
論文名稱:激發試驗:探討人體在行動電話基地台電磁波下之健康效應
論文名稱(外文):The health effects of the electromagnetic field associated with cell phone base station: A provocation study
指導教授:郭浩然郭浩然引用關係
指導教授(外文):How-Ran Guo
學位類別:碩士
校院名稱:國立成功大學
系所名稱:環境醫學研究所
學門:醫藥衛生學門
學類:公共衛生學類
論文種類:學術論文
論文出版年:2012
畢業學年度:100
語文別:英文
論文頁數:65
中文關鍵詞:電磁場電磁波敏感症激發試驗行動電話基地台
外文關鍵詞:electromagnetic field (EMF)electromagnetic hypersensitivity syndrome (EHS)provocation studycell phone base station
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研究目的:評估電磁波對生理的短期影響。
實驗設計:實驗對象為年齡在20-69歲,無懷孕、腦損傷、癲癇、心血管疾病、慢性皮膚病、配戴助聽器、及精神方面疾病(如幽閉恐懼症、焦慮症)近6個月接受治療者。激發實驗在能屏蔽電磁波的實驗室中進行,暴露的電磁波射源為2G與3G行動電話基地台頻率之混和(0.1mW/cm2),採交叉雙盲之隨機暴露。受試者以問卷評估感受症狀,以生理量測儀器連續記錄動態心電圖、動脈氧血紅素飽和度、脈搏、血壓、體溫;每個人暴露30分鐘的電磁波,30分鐘的清除時間,及30分鐘的假暴露。
結果:符合條件完成試驗者共102名,其中有10名自陳有電磁波敏感。在問卷中自陳對電磁波環境較敏感之族群對容易感到有不舒適症狀,且達統計上顯著差異(p〈0.05);回覆相關症狀較一般族群顯著者有:噁心、注意力下降、焦慮、頭痛、耳朵不適、心悸、暈眩。受試者對電磁波環境的不舒服症狀依感受問卷之評估,並不會因電磁波的暴露而有統計上之差異。以ANOVA重複測量之混和效應分析受試者的收縮壓、舒張壓、平均血壓、心跳及心跳之變異在受試者暴露與非暴露期間的固定效應和隨機效應發現:收縮壓、舒張壓、平均血壓、心跳及心跳變異皆有顯著之個人差異,平均血壓則依年齡及性別而有不同,但與暴露與否無關。短期暴露於0.1mW/cm2電磁波下有個人之隨機差異,但電磁波暴露無明顯之固定效應。自陳對電磁波環境較敏感族群無論是在有或是沒有電磁波暴露的時段,他們都有比較高的比率回覆「感受到電磁波」。
結論:實驗結果發現短期暴露於0.1mW/cm2電磁波下並沒有明顯之健康效應。

Objective: To evaluate the acute health effects of the electromagnetic field (EMF) associated with cell phone base station on humans.
Design: We recruited participants aged between 20 and 69 years and conducted a double-blind crossover provocation study. Candidates who had a history of brain injury, epilepsy, cardiovascular disease, claustrophobiaor, or psychiatric disease with medical treatment during the recent 6 months, or were pregnant at the time of recruitment were excluded. The participants were asked to complete questionnaires of subjective symptoms and received monitoring of electrocardiography (EKG), oxyhemoglobin saturation (by pulse oximetry), pulse rate, blood pressure, skin temperature, and heart rate variability in an EMF-shielding room. Each participant received an exposure session of EMF with frequency mimicking cell phone base stations and a sham session. The sequence of the sessions was assigned by random and unknown to both the participants and the observers.
Results: A total of 102 persons participated in the study, including 10 who reported having “electromagnetic hypersensitivity” (sensitive group) and 92 who did not (regular group). The sensitive group reported more uncomfortable symptoms when they were exposed to electronic products, including nausea, decreased attention, anxiety, headache, ear discomfort, palpitations, and dizziness. However, there were no differences in physiological data between the two groups during or after EMF exposure. Random effects of systolic blood pressure, diastolic blood pressure, mean artery pressure, pulse rate, and heart rate variability were observed between the exposure and sham sessions. Whereas fixed effects of age and sex on the systolic blood pressure, diastolic blood pressure, and mean artery pressure were noted, time sequence and exposure were not associated with those parameters. The proportion of accurate perception was 5% for exposure sessions and 95% for sham sessions in both two groups. The sensitive group tended to report feeling EMF more frequently in both exposure and sham sessions, but the differences did not reach statistical significance.
Conclusion: We did not observed any significant health effects of EMF with the frequencies similar to cell phone base stations.

1.INTRODUCTION 1
1.1 BACKGROUND 1
1.2 DEFINITION OF ELECTROMAGNETIC FIELD 3
1.3 DEFINITION OF THE ELECTROMAGNETIC HYPERSENSITIVE SYNDROME 5
1.4 REVIEW OF LITERATURE 6
1.4.1 Double-blind provocation studies 6
1.4.2 Can evidence change belief? .. 10
2.MATERIAL AND METHOD 11
2.1 SUBJECTS 11
2.2 RELIABILITY AND VALIDITY OF QUESTIONNAIRES 11
2.3 INSTITUTIONAL REVIEW BOARD (IRB) 13
2.4 EXPERIMENT DESIGN 14
2.5 CROSS-OVER AND DOUBLE-BLIND PROVOCATION STUDY 17
2.6 EXPECT THE SIZE OF SUBJECTS 19
3.RESULTS OF EXPERIMENT 19
3.1 STATISTICAL ANALYSIS 19
3.2 DEMOGRAPHIC ANALYSIS 20
3.3 ANALYSIS OF THE EXPERIENCE QUESTIONNAIRE OF PROVOCATION STUDY 21
3.4 PHYSIOLOGICAL DATA ANALYSIS 22
3.5 CARRY-OVER EFFECT 23
4.DISCUSSION 24
5.THE LIMITATION OF STUDY 28
6.REFERENCES 30

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