(18.204.2.190) 您好!臺灣時間:2021/04/22 08:12
字體大小: 字級放大   字級縮小   預設字形  
回查詢結果

詳目顯示:::

我願授權國圖
: 
twitterline
研究生:黃萱軒
研究生(外文):Hsuan-Hsuan Huang
論文名稱:台灣試管嬰兒相關因子影響胎兒性別之研究
論文名稱(外文):Factors associated with gender of in-vitro fertilization offspring in Taiwan
指導教授:黃雅莉黃雅莉引用關係
學位類別:碩士
校院名稱:臺北醫學大學
系所名稱:公共衛生學研究所
學門:醫藥衛生學門
學類:公共衛生學類
論文種類:學術論文
論文出版年:2012
畢業學年度:100
語文別:中文
論文頁數:154
中文關鍵詞:試管嬰兒、胎兒性別、減胎、卵巢過度刺激症候群、單一精子卵質內顯微注射
外文關鍵詞:in vitro fertilizationsex ratiofetal reductionovarian hyperstimulation syndromeintra cytoplasmic sperm injection.
相關次數:
  • 被引用被引用:1
  • 點閱點閱:205
  • 評分評分:系統版面圖檔系統版面圖檔系統版面圖檔系統版面圖檔系統版面圖檔
  • 下載下載:0
  • 收藏至我的研究室書目清單書目收藏:0
第一章 緒論 1
第一節 研究背景 1
第二節 研究目的 3
第二章 文獻探討 4
第一節 一般新生兒胎兒性別的影響因子 4
壹 社會人口學因子 4
貳 環境因子 7
參 病理因子 9
肆 賀爾蒙因子 9
伍 胎兒出生年 10
第二節 試管嬰兒新生兒胎兒性別的影響因子 11
壹 試管嬰兒(In vitro fertilization/Embryo transfer, IVF/ET) 11
貳 顯微操作因子(Micromanipulation technique) 12
參 胚胎種類 15
肆 卵巢過度刺激症候群(Ovarian hyperstimulation syndrome, OHSS) 16
伍 減胎 17
陸 不孕原因 18
柒 雙親年齡 19
捌 胚囊數 19
玖 取卵數 20
第三章 研究方法 22
第一節 研究架構與假設 22
壹 試管嬰兒-以胚囊數和出生週數分層 23
貳 試管嬰兒-以取卵數和出生週數分層 24
參 試管嬰兒-以胚胎受精卵植入數和出生週數分層 25
第二節 研究資料來源 26
第三節 研究對象 26
壹 試管嬰兒-以胚囊數和出生週數分層 27
貳 試管嬰兒-以取卵數和出生週數分層 28
參 試管嬰兒-以胚胎受精卵植入數和出生週數分層 29
第四節 研究變項的定義與測量 30
壹 試管嬰兒相關因子 30
第五節 資料處理及統計分析 32
壹 描述性統計&雙變項分析 32
貳 多變項分析 32
第四章 研究結果 33
第一節 描述性統計 33
第二節 以胚囊數和出生週數分層 36
壹 胚囊數1個早產 36
貳 胚囊數2個早產 42
參 胚囊數大於等於2個早產 44
肆 胚囊數1個足月產 49
伍 胚囊數2個足月產 55
陸 胚囊數大於等於2個足月產 61
第三節 以取卵數和出生週數分層 66
壹 取卵數1-7個早產 66
貳 取卵數8-12個早產 72
參 取卵數大於等於13個早產 78
肆 取卵數1-7個足月產 84
伍 取卵數8-12個足月產 89
陸 取卵數大於等於13個足月產 95
第四節 以胚胎受精卵植入數和出生週數分層 101
壹 胚胎受精卵植入數1-3個早產 101
貳 胚胎受精卵植入數大於3個早產 106
參 胚胎受精卵植入數1-3個足月產 111
肆 胚胎受精卵植入數大於3個足月產 116
第五章 討論 121
第一節 父親年齡 121
第二節 母親年齡 121
第三節 雙親年齡差距(父減母) 122
第四節 減胎數 123
第五節 顯微操作方式 124
第六節 卵巢過度刺激症候群 126
第七節 不孕原因 127
第八節 研究貢獻 128
第九節 研究限制 129
第十節 結論 129


Abramov, Y., U. Elchalal, et al. (1998). "Obstetric outcome of in vitro fertilized pregnancies complicated by severe ovarian hyperstimulation syndrome: a multicenter study." Fertility and Sterility 70(6): 1070-1076.
Abu-Musa, A. A., I. M. Usta, et al. (2009). "Effect of 1-month war in Lebanon on sex ratio." Fertility and Sterility 91(4 Suppl): 1571-1573.
Alfarawati, S., E. Fragouli, et al. (2011). "The relationship between blastocyst morphology, chromosomal abnormality, and embryo gender." Fertility and Sterility 95(2): 520-524.
Antsaklis, A., A. P. Souka, et al. (2004). "Embryo reduction versus expectant management in triplet pregnancies." J Matern Fetal Neonatal Med 16(4): 219-222.
Arnold, F. and S. Rutstein (1997). "Sex ratio unaffected by parental age gap." Nature 390(6657): 242-242.
Astolfi, P. and L. A. Zonta (1999). "Sex ratio and parental age gap." Hum Biol 71(1): 135-141.
Barczyk, A. (2001). "Sperm capacitation and primary sex ratio." Medical Hypotheses 56(6): 737-738.
Bassam A. Elhelw, M., MFFP , M. Moustafa M. El Sadek, et al. (2004). "Assisted hatching: routine or selective application in IVF." Middle East Fertility Society Journal 9(3): 198-201.
Becker, S., S. Ural, et al. (2004). "Fetal gender and sonographic assessment of crown-rump length: implications for multifetal pregnancy reduction." Ultrasound Obstet Gynecol 24(4): 399-401.
Beerendonk, C. C., P. A. van Dop, et al. (1998). "Ovarian hyperstimulation syndrome: facts and fallacies." Obstetrical & Gynecological Survey 53(7): 439-449.
Beratis, N. G., A. Asimacopoulou, et al. (2008). "Association of secondary sex ratio with smoking and parity." Fertility and Sterility 89(3): 662-667.
Cagnacci, A., A. Renzi, et al. (2004). "Influences of maternal weight on the secondary sex ratio of human offspring." Human Reproduction 19(2): 442-444.
Cheang, C. U., L. S. Huang, et al. (2007). "A comparison of the outcomes between twin and reduced twin pregnancies produced through assisted reproduction." Fertility and Sterility 88(1): 47-52.
Chiaffarino, F., M. P. Baldini, et al. (2011). "Prevalence and incidence of depressive and anxious symptoms in couples undergoing assisted reproductive treatment in an Italian infertility department." Eur J Obstet Gynecol Reprod Biol 158(2): 235-241.
Christianson, M. S., M. M. Yates, et al. (2009). "Intracytoplasmic Sperm Injection for Male Factor Infertility: Effects on Gender of Offspring." Fertility and Sterility 91: S12-S12.
Council, N. H. a. M. R. (2007). "Ethical Guidelines on the Use of Assisted Reproductive Technology in Clinical Practice and Research." http://www.nhmrc.gov.au/publications/synopses/e78syn.htm.
Courbiere, B., V. Oborski, et al. (2011). "Obstetric outcome of women with in vitro fertilization pregnancies hospitalized for ovarian hyperstimulation syndrome: a case-control study." Fertility and Sterility 95(5): 1629-1632.
Das, S., D. Blake, et al. (2009). "Assisted hatching on assisted conception (IVF and ICSI)." Cochrane Database Syst Rev(2): CD001894.
Dean, J. H., M. G. Chapman, et al. (2010). "The effect on human sex ratio at birth by assisted reproductive technology (ART) procedures--an assessment of babies born following single embryo transfers, Australia and New Zealand, 2002-2006." BJOG 117(13): 1628-1634.
Ein-Mor, E., D. Mankuta, et al. (2010). "Sex ratio is remarkably constant." Fertility and Sterility 93(6): 1961-1965.
Farah, L. M., L. M. Rossi, et al. (2005). "Sex ratio and cleavage rhythm in embryos from ICSI." Fertility and Sterility 84: S330-S331.
Fedder, J., A. Gabrielsen, et al. (2007). "Malformation rate and sex ratio in children conceived after ICSI, using epididymal or testicular sperm." Acta Obstetricia Et Gynecologica Scandinavica 86(1): 117-117.
Fujii, M., R. Matsuoka, et al. (2010). "Perinatal risk in singleton pregnancies after in vitro fertilization." Fertility and Sterility 94(6): 2113-2117.
Fukuda, M., K. Fukuda, et al. (2002). "Parental periconceptional smoking and male: female ratio of newborn infants." Lancet 359(9315): 1407-1408.
Fukuda, M., K. Fukuda, et al. (1998). "Decline in sex ratio at birth after Kobe earthquake." Human Reproduction 13(8): 2321-2322.
Fukuda, M., K. Fukuda, et al. (2011). "The sex ratio of offspring is associated with the mothers'' age at menarche." Human Reproduction 26(6): 1551-1554.
Ghannadii, A., M. Kazerooni, et al. (2011). "The effects of laser assisted hatching on pregnancy rates." Iranian Journal of Reproductive Medicine 9(2): 95-98.
Ghobara, T. S., D. J. Cahill, et al. (2006). "Effects of assisted hatching method and age on implantation rates of IVF and ICSI." Reproductive Biomedicine Online 13(2): 261-267.
Graffelman, J., E. F. Fugger, et al. (1999). "Human live birth and sperm-sex ratios compared." Human Reproduction 14(11): 2917-2920.
Grech, V., C. Savona-Ventura, et al. (2002). "Research pointers: Unexplained differences in sex ratios at birth in Europe and North America." BMJ 324(7344): 1010-1011.
Gutierrez-Adan, A., J. Granados, et al. (2001). "Influence of glucose on the sex ratio of bovine IVM/IVF embryos cultured in vitro." Reprod Fertil Dev 13(5-6): 361-365.
Gutierrez-Adan, A., B. Pintado, et al. (2000). "Demographic and behavioral determinants of the reduction of male-to-female birth ratio in Spain from 1981 to 1997." Hum Biol 72(5): 891-898.
Hagemann, A. R., S. E. Lanzendorf, et al. (2010). "A prospective, randomized, double-blinded study of assisted hatching in women younger than 38 years undergoing in vitro fertilization." Fertility and Sterility 93(2): 586-591.
Hakko, H., P. Rasanen, et al. (1998). "Parental age gap and child sex ratio--fact or fiction?" Int J Epidemiol 27(5): 929-930.
Helle, S. (2008). "Height, weight, body mass index and offspring sex at birth in contemporary Finnish women." Journal of Theoretical Biology 252(4): 773-775.
Helle, S., S. Helama, et al. (2008). "Temperature-related birth sex ratio bias in historical Sami: warm years bring more sons." Biology Letters 4(1): 60-62.
Helmerhorst, F. M., D. A. Perquin, et al. (2004). "Perinatal outcome of singletons and twins after assisted conception: a systematic review of controlled studies." BMJ 328(7434): 261.
Hentemann, M. A., S. Briskemyr, et al. (2009). "Blastocyst transfer and gender: IVF versus ICSI." Journal of Assisted Reproduction and Genetics 26(8): 433-436.
Heron, J. and A. Ness (2004). "Lack of association between smoking behavior and the sex ratio of offspring in the Avon Longitudinal Study of Parents and Children." Fertility and Sterility 81(3): 700-702.
Hwang, J. L., H. S. Pan, et al. (2002). "Comparison of the outcomes of primary twin pregnancies and twin pregnancies following fetal reduction." Arch Gynecol Obstet 267(2): 60-63.
Jackson, R. A., K. A. Gibson, et al. (2004). "Perinatal outcomes in singletons following in vitro fertilization: a meta-analysis." Obstetrics and Gynecology 103(3): 551-563.
Jacobsen, R., E. Bostofte, et al. (2000). "Fertility and offspring sex ratio of men who develop testicular cancer: a record linkage study." Human Reproduction 15(9): 1958-1961.
Jacobsen, R., H. Moller, et al. (1999). "Natural variation in the human sex ratio." Human Reproduction 14(12): 3120-3125.
James, W. H. (1996). "Evidence that mammalian sex ratios at birth are partially controlled by parental hormone levels at the time of conception." Journal of Theoretical Biology 180(4): 271-286.
James, W. H. (2009). "The variations of human sex ratio at birth during and after wars, and their potential explanations." Journal of Theoretical Biology 257(1): 116-123.
Jansen, R. P. (2003). "The effect of female age on the likelihood of a live birth from one in-vitro fertilisation treatment." Med J Aust 178(6): 258-261.
Jones, H. W., Jr., G. S. Jones, et al. (1982). "The program for in vitro fertilization at Norfolk." Fertility and Sterility 38(1): 14-21.
Juan J.Tarin, R. B., Amparo Baviera, Maria Bonada and Antonio Cano (1995). "Sex selection may be inadvertently performed in in-vitro fertilization-embryo transfer programmes." Human Reproduction 10: 7.
Kallen, B., O. Finnstrom, et al. (2005). "In vitro fertilization (IVF) in Sweden: infant outcome after different IVF fertilization methods." Fertility and Sterility 84(3): 611-617.
Khashan, A. S., T. B. Henriksen, et al. (2010). "Parental Celiac Disease and Offspring Sex Ratio." Epidemiology 21(6): 913-914.
Khashan, A. S., P. B. Mortensen, et al. (2009). "Sex ratio at birth following prenatal maternal exposure to severe life events: a population-based cohort study." Human Reproduction 24(7): 1754-1757.
Landy, H. J. and L. G. Keith (1998). "The vanishing twin: a review." Hum Reprod Update 4(2): 177-183.
Lerchl, A. (1999). "Sex ratios at birth and environmental temperatures." Naturwissenschaften 86(7): 340-342.
Lin, P. Y., F. J. Huang, et al. (2009). "Comparison of the offspring sex ratio between fresh and vitrification-thawed blastocyst transfer." Fertility and Sterility 92(5): 1764-1766.
Luke, B., M. B. Brown, et al. (2009). "The sex ratio of singleton offspring in assisted-conception pregnancies." Fertility and Sterility 92(5): 1579-1585.
Luke, B., M. B. Brown, et al. (2010). "Factors associated with ovarian hyperstimulation syndrome (OHSS) and its effect on assisted reproductive technology (ART) treatment and outcome." Fertility and Sterility 94(4): 1399-1404.
Ma, S., T. Rowe, et al. (2006). "Impact of assisted hatching on the outcome of intracytoplasmic sperm injection: a prospective, randomized clinical trial and pregnancy follow-up." Fertility and Sterility 85(4): 895-900.
Macdougall, I. C. (1992). "Treatment of renal anemia with recombinant human erythropoietin." Curr Opin Nephrol Hypertens 1(2): 210-219.
MacDougall, L. T., C. C. Magoon, et al. (1992). "Dirofilaria repens manifesting as a breast nodule. Diagnostic problems and epidemiologic considerations." Am J Clin Pathol 97(5): 625-630.
MacDougall, M. J., S. L. Tan, et al. (1992). "In-vitro fertilization and the ovarian hyperstimulation syndrome." Human Reproduction 7(5): 597-600.
Manning, J. T., R. H. Anderton, et al. (1997). "Parental age gap skews child sex ratio." Nature 389(6649): 344.
Mathews, T. J. and B. E. Hamilton (2005). "Trend analysis of the sex ratio at birth in the United States." Natl Vital Stat Rep 53(20): 1-17.
Mathur, R. S. and J. M. Jenkins (2000). "Is ovarian hyperstimulation syndrome associated with a poor obstetric outcome?" Br J Obstet Gynaecol 107(8): 943-946.
Matsuo, K., N. Ushioda, et al. (2009). "Parental aging synergistically decreases offspring sex ratio." J Obstet Gynaecol Res 35(1): 164-168.
McLachlan, J. C. and H. Storey (2003). "Hot male: can sex in humans be modified by temperature?" Journal of Theoretical Biology 222(1): 71-72.
Michelle, D. and K. Richard (2006). "Ovarian hyperstimulation syndrome: Aetiology, prevention and management." Reviews in Gynaecological and Perinatal Practice 6: 7.
Mills, J. L., L. England, et al. (2003). "Cigarette smoking and the male-female sex ratio." Fertility and Sterility 79(5): 1243-1245.
Mocarelli, P., P. M. Gerthoux, et al. (2000). "Paternal concentrations of dioxin and sex ratio of offspring." Lancet 355(9218): 1858-1863.
Moller, H. (1998). "Trends in sex-ratio, testicular cancer and male reproductive hazards: Are they connected?" Apmis 106(1): 232-238.
Nandita, P., P. Hrishikesh, et al. (2011). "Perinatal Outcome After Multifetal Reduction: A Study of 12 Cases." The Journal of Obstetrics and Gynecology of India: 5.
NATIONS, U. (1955). "Methods of Appraisal of Quality of Basic Data for Population Estimates." Department of Economic and Social Affairs Population Branch New York: 76.
Nevo, O., E. Avisar, et al. (2003). "Neonatal course and outcome of twins from reduced multifetal pregnancy versus non-reduced twins." Israel Medical Association Journal 5(4): 245-248.
Palermo, G., H. Joris, et al. (1992). "Pregnancies after intracytoplasmic injection of single spermatozoon into an oocyte." Lancet 340(8810): 17-18.
Pharoah, P. O. and Y. Adi (2000). "Consequences of in-utero death in a twin pregnancy." Lancet 355(9215): 1597-1602.
Pinborg, A., O. Lidegaard, et al. (2007). "Vanishing twins: a predictor of small-for-gestational age in IVF singletons." Human Reproduction 22(10): 2707-2714.
Pinborg, A., O. Lidegaard, et al. (2005). "Consequences of vanishing twins in IVF/ICSI pregnancies." Human Reproduction 20(10): 2821-2829.
Pinborg, A., A. Loft, et al. (2010). "Infant outcome of 957 singletons born after frozen embryo replacement: The Danish National Cohort Study 1995-2006." Fertility and Sterility 94(4): 1320-1327.
Raziel, A., M. Schachter, et al. (2009). "Outcome of IVF pregnancies following severe OHSS." Reproductive Biomedicine Online 19(1): 61-65.
Rjasanowski, I., I. Kloting, et al. (1998). "Altered sex ratio in offspring of mothers with insulin-dependent diabetes mellitus." Lancet 351(9101): 497-498.
Rossi, R. M., V. A. D. Rosa, et al. (2003). "Influence of age gap and parents’ ethnicity on the sex of the first born child." REVISTA DE BIOLOGIA E CIENCIAS DA TERRA 3.
Rueness, J., L. Vatten, et al. (2011). "The human sex ratio: effects of maternal age." Human Reproduction.
Saadat, M. (2008). "Decline in sex ratio at birth after Bam (Kerman Province, Southern Iran) earthquake." Journal of Biosocial Science 40(6): 935-937.
Sampson, A. and L. C. de Crespigny (1992). "Vanishing twins: the frequency of spontaneous fetal reduction of a twin pregnancy." Ultrasound Obstet Gynecol 2(2): 107-109.
Schenker, J. G. and D. Weinstein (1978). "Ovarian hyperstimulation syndrome: a current survey." Fertility and Sterility 30(3): 255-268.
Scher, A. I., B. Petterson, et al. (2002). "The risk of mortality or cerebral palsy in twins: a collaborative population-based study." Pediatric Research 52(5): 671-681.
Shokeir, T., M. El-Shafei, et al. (2010). "Submucous myomas and their implications in the pregnancy rates of patients with otherwise unexplained primary infertility undergoing hysteroscopic myomectomy: a randomized matched control study." Fertility and Sterility 94(2): 724-729.
Silverman, A. Y., S. R. Stephens, et al. (2002). "Female sex selection using clomiphene citrate and albumin separation of human sperm." Human Reproduction 17(5): 1254-1256.
Steptoe, P. C. and R. G. Edwards (1978). "Birth after the reimplantation of a human embryo." Lancet 2(8085): 366.
Stone, J., L. Ferrara, et al. (2008). "Contemporary outcomes with the latest 1000 cases of multifetal pregnancy reduction (MPR)." American Journal of Obstetrics and Gynecology 199(4): 406 e401-404.
Tarin, J. J., R. Bernabeu, et al. (1995). "Sex selection may be inadvertently performed in in-vitro fertilization-embryo transfer programmes." Human Reproduction 10(11): 2992-2998.
Templeton, A., J. K. Morris, et al. (1996). "Factors that affect outcome of in-vitro fertilisation treatment." Lancet 348(9039): 1402-1406.
Torok, O., R. Lapinski, et al. (1998). "Multifetal pregnancy reduction is not associated with an increased risk of intrauterine growth restriction, except for very-high-order multiples." American Journal of Obstetrics and Gynecology 179(1): 221-225.
Trivers, R. L. and D. E. Willard (1973). "Natural selection of parental ability to vary the sex ratio of offspring." Science 179(4068): 90-92.
Tummers, P., P. De Sutter, et al. (2003). "Risk of spontaneous abortion in singleton and twin pregnancies after IVF/ICSI." Human Reproduction 18(8): 1720-1723.
Tur-Kaspa, I., N. Katz, et al. (2007). "Does IVF with PGD and blastocyst transfer affect offspring''s sex-ratio?" Fertility and Sterility 88: S235-S235.
van der Gaast, M. H., M. J. Eijkemans, et al. (2006). "Optimum number of oocytes for a successful first IVF treatment cycle." Reproductive Biomedicine Online 13(4): 476-480.
van der Gaast, M. H., M. J. C. Eijkemans, et al. (2006). "Optimum number of oocytes for a successful first IVF treatment cycle." Reproductive Biomedicine Online 13(4): 476-480.
Verlinsky, Y., J. Cohen, et al. (2004). "Over a decade of experience with preimplantation genetic diagnosis: a multicenter report." Fertility and Sterility 82(2): 292-294.
Wiegmann, T. B., A. M. Chonko, et al. (1992). "The role of disease duration and hypertension in albumin excretion of type I diabetes mellitus." Journal of the American Society of Nephrology 2(11): 1587-1592.
Yang, C. Y., H. Cheng, et al. (2000). "Chlorination of drinking water and sex ratio at birth in Taiwan." Journal of Toxicology and Environmental Health-Part A 60(7): 471-476.
Zeilmaker, G. H., A. T. Alberda, et al. (1984). "Two pregnancies following transfer of intact frozen-thawed embryos." Fertility and Sterility 42(2): 293-296.
中華民國內政部 (2007). "人工生殖法." 中華民國內政部.
江其鑫 (1998). "卵巢過度刺激症候群." 中華民國內膜異位症婦女協會會刊 5(1): 1.
吳立偉, 胡昆宜, et al. (2009). "食物過敏." 家庭醫學與基層醫療 24(4): 7.
林建男 (2006). "台灣集集地震對出生性別比及出生結果之影響." 碩士論文.
原新 and 涂肇慶 (2004). "中國大陸出生性別比偏高之分析." 人口學刊 29: 35.
連苑晴 (2011). "台灣出生性別比失衡與重男輕女 " 碩士論文.
陳淑君 (2003). "男性精液品質長期趨勢分析及其危險因子之探討." 碩士論文.
陳欽德 and 楊友仕 (1997). "婦產科:卵巢過度刺激症候群." 臺灣醫學 1(5): 6.
黃莉文 (1990). "不孕症治療法─試管嬰兒." 慈濟醫學雜誌 2卷(1期): 4.
张印峰, 徐慧颖, et al. (2010). "冻融胚胎移植周期患者年龄及移植胚胎个数与妊娠结局的关系." 天津醫藥 38(11): 3.
行政院衛生署國民健康局 (2003-2011). "民國八十七-九十八年台灣地區人工生殖施行結果分析報告." 50.
行政院衛生署國民健康局 (2011). "民國九十八年台灣地區人工生殖施行結果分析報告."


QRCODE
 
 
 
 
 
                                                                                                                                                                                                                                                                                                                                                                                                               
第一頁 上一頁 下一頁 最後一頁 top
系統版面圖檔 系統版面圖檔