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研究生:朱嘉宙
研究生(外文):Chia-Chou Chu
論文名稱:麩醯胺對DSS誘發急性腸炎小鼠免疫調節之影響
論文名稱(外文):The immuno-regulatory effects of glutamine on dextran sulfate sodium-induced acute colitis in mice
指導教授:趙振瑞趙振瑞引用關係
學位類別:博士
校院名稱:臺北醫學大學
系所名稱:藥學系(博士班)
學門:醫藥衛生學門
學類:藥學學類
論文種類:學術論文
論文出版年:2011
畢業學年度:100
語文別:中文
論文頁數:128
中文關鍵詞:腸炎麩醯胺dextran sulfate sodiumT helper cellsinterleukin-17
外文關鍵詞:colitisdextran sulfate sodiumglutamineT helper lymphocytesinterleukin-17
相關次數:
  • 被引用被引用:0
  • 點閱點閱:378
  • 評分評分:
  • 下載下載:4
  • 收藏至我的研究室書目清單書目收藏:0
摘要 I
Abstract II
總目錄 IV
圖目次 VI
表目次 VII
縮寫表 VIII
第一章 研究動機與目的 1
第二章 文獻回顧 2
第一節 發炎性腸道疾病 2
第二節 Dextran sulfate sodium誘發腸炎動物模式 7
第三節 發炎性腸道疾病之診療 10
第四節 輔助型T淋巴細胞 14
第五節 輔助型T淋巴細胞次群 - Th17 18
第六節 麩醯胺 21
第三章 實驗設計 26
第四章 預防性投予麩醯胺實驗 27
第一節 實驗方法 27
第二節 分析項目與方法 31
第三節 實驗材料 38
第四節 統計分析 42
第五節 結果 43
第五章 腸炎後補充麩醯胺實驗 53
第一節 實驗方法 53
第二節 分析項目與方法 56
第三節 實驗材料 62
第四節 統計分析 65
第五節 結果 66
第六章 討論 83
第一節 Gln對輔助型T淋巴細胞相關細胞激素之影響 85
第二節 Gln對haptoglobin與腸道中免疫球蛋白之影響 87
第三節 Gln對腸道發炎反應之影響 88
第四節 Gln對腸道中TLR4與NF-κB之影響 90
第五節 Gln對腸道修復之影響 92
第六節 Gln對腸道中細胞凋亡之影響 93
第七節 Gln改善腸道損傷之影響 94
第七章 結論 96
第八章 參考文獻 98


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