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研究生:蔡邦亮
研究生(外文):Pang-LiangTsai
論文名稱:血管支架塑性成型分析
論文名稱(外文):A Study On Stent Plastic Forming
指導教授:尤芳忞
指導教授(外文):Fan-Ming Yu
學位類別:碩士
校院名稱:國立成功大學
系所名稱:航空太空工程學系專班
學門:工程學門
學類:機械工程學類
論文種類:學術論文
論文出版年:2013
畢業學年度:101
語文別:中文
論文頁數:85
中文關鍵詞:血管支架置入術有限元素狗骨頭變化率
外文關鍵詞:PTCAfinite elementDogboning rate
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血管支架置入術是目前治療冠心病的最流行手段,但現行支架仍然有較高的再狹窄問題。通過對血管支架進行結構優化設計,改變其置放時的膨脹行為則是一個能夠減少支架在置入時對血管內膜的損傷,從而降低支架內再狹窄率的有效途徑之一。

本論文使用SolidWork軟件建立3D模型,並使用ANSYS有限元軟件模擬血管支架歷經氣球加壓與卸壓的變形過程,討論支架徑向、縱向回彈及狗骨頭變化率,並變更支架設計參數(如厚度、環狀寬度等),選擇最佳設計參數,從而優化支架設計。

優化後支架再加入血管三層膜及斑塊,模擬支架置入時氣球加壓及卸壓過程,並分析支架塑性成型變形及應力分布。結果顯示優化後支架可有效降低狗骨頭變化率,氣球膨脹時可均勻擴張,達到支撐及擴張血管效果,另一方面也驗證支架在設計時血管回壓效應,為絕不可忽略重要因素。

PTCA is currently most popular means of treatment of coronary heart disease, but the current stent still has higher restenosis problem. By one effective ways to structure optimization design is able to reduce the vascular intimal injury when stent placement.
Computer aided design software SolidWork is used to build the solid model and then CAE software ANSYS is used to simulate the deformation of the stent after balloon infla-tion and deflation.
A typical stent is analyzed.Discussion of the the stent radial, longitudinal recoiling and Dogboning rate, then change the design parameters (such as the thickness and width of ring, etc.), select the best design parameters to optimize design of the stent.
The results indicate that the optimized stent can reduce the rate of dogboning effec-tively,and achieve support and inflation of blood vessels by uniform expansion of the stent .On the other hand, also verify that considering of the atherosclerotic artery may affect the calculated stent deformation and stress distributions significantly is never ignore important factors.

中文摘要...........................................................I
英文摘要...........................................................Ⅱ
誌謝...............................................................Ⅲ
目錄...............................................................Ⅳ
圖目錄.............................................................Ⅶ
表目錄.............................................................X

第一章 緒論
1-1 前言........................................................1
1-2 冠心病治療方式..............................................3
1-3 冠狀動脈支架種類............................................5
1-4 文獻探討....................................................9
1-5 血管支架有限元設計流程.....................................11
1-6 研究動機與目標.............................................12
1-7 本文研究主要內容...........................................13
第二章 研究方法
2-1 有限元素軟件介紹...........................................14
2-2 有限元素模型...............................................15
2-3 材料特性與單元屬性.........................................24
2-4 邊界條件、接觸條件與負載條件...............................25
2-5 相關理論說明...............................................28
2-6 網格劃分與精準度分析.......................................29
2-7 評估標準...................................................34
2-8 修改模型...................................................38
2-8-1 改變支架厚度...........................................38
2-8-2 環狀寬度...............................................38
第三章塑性成型分析
3-1 前言.......................................................40
3-2 原設計支架塑性成型分析.....................................40
3-2-1 有無血管效應變形分析...................................40
3-2-2 應力分布...............................................41
3-2-3 小結...................................................48
3-3 支架厚度影響...............................................48
3-3-1 變形分析...............................................48
3-3-2 應力分析...............................................49
3-3-3 小結...................................................55
3-4 支架環狀寬度影響...........................................56
3-4-1 變形分析...............................................56
3-4-2 應力分析...............................................57
3-4-3 小結...................................................62
第四章 優化設計
4-1 前言.......................................................63
4-2 氣球長度縮減...............................................64
4-2-1 變形分析與原設計支架比較...............................64
4-2-2 應力分布................................................65
4-2-3 小結....................................................65
4-3 支架末端強化設計...........................................68
4-3-1 變形分析與比較.........................................69
4-3-2 應力分析...............................................69
4-3-3 小結...................................................69
4-4 優化設計支架加入血管效應影響...............................73
4-4-1 變形分析...............................................73
4-4-2 應力分布...............................................73
第五章 結論與未來展望
5-1 結論.......................................................78
5-2 未來展望...................................................79
參考文獻...........................................................82
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