(3.236.214.19) 您好!臺灣時間:2021/05/09 23:08
字體大小: 字級放大   字級縮小   預設字形  
回查詢結果

詳目顯示:::

我願授權國圖
: 
twitterline
研究生:陳凱威
研究生(外文):Kai-Wei Chen
論文名稱:抗菌自組裝薄膜光學鏡片製程優化與性能研究
論文名稱(外文):A Study of Antibacterial Self-Assembled Layers of Optics Lens
指導教授:洪政豪洪政豪引用關係
指導教授(外文):Jeng-Haur Horng
學位類別:碩士
校院名稱:國立虎尾科技大學
系所名稱:機械與機電工程研究所
學門:工程學門
學類:機械工程學類
論文種類:學術論文
論文出版年:2013
畢業學年度:101
語文別:中文
論文頁數:97
中文關鍵詞:自組裝薄膜接觸角黏附力臨界負荷抗菌光學鏡片疏水性
外文關鍵詞:optical lensself-assembled monolayeradhesion forcesurface forcescontact angleantibacterial
相關次數:
  • 被引用被引用:2
  • 點閱點閱:283
  • 評分評分:系統版面圖檔系統版面圖檔系統版面圖檔系統版面圖檔系統版面圖檔
  • 下載下載:0
  • 收藏至我的研究室書目清單書目收藏:1
功能性薄膜因具有不同表面特性,於不同場合中被廣泛應用,例如疏水性薄膜、抗菌性薄膜、抗磨損薄膜等。自組裝單分子薄膜(SAMs)具有疏水特性,利用單分子自發性吸附於基材表面的特性,在基材表面形成規則且緊密排列的單分子薄膜結構,能夠有效降低材料表面的黏附特性,製作方法簡單,能廣泛應用於生醫材料、光學、電子機械、微機電工程等領域。
本文建立於混合自組裝分子薄膜技術,使用有機矽烷類的自組裝薄膜混合抗菌藥劑附著光學鏡片上,觀察薄膜親疏水特性、薄膜組成情形、抗菌能力、表面清潔度,再利用田口方法以最高接觸角度為目標,以不同浸泡溫度、烘乾溫度、藥劑濃度及浸泡時間等實驗參數,製作自組裝混合分子薄膜於光學鏡片上,得到各自組裝混合分子薄膜最佳接觸角度,OTS自組裝膜為106.3°、OTS10%抗菌混合膜為103.3°、OTS50%抗菌混合膜99.7°、ODS自組裝膜109°、ODS10%抗菌混合膜為102.1°、ODS50%抗菌混合膜為96.1°,並進行金黃葡萄球菌的抗菌檢驗,只需加入重量百分濃度10%的抗菌藥劑便能擁有極佳的抗菌效果。此外混合TEOS藥劑取得更高的接觸角度,分析薄膜表面成分,得到分子薄膜吸附與組成的影響因子,在提高接觸角度的前提之下,控制薄膜的組成情形,得到高接觸角及高清潔度之表面,TEOS接觸角度為137.8°、TEOS10%抗菌混合膜接觸角度為130.5、TEOS50%抗菌混合膜接觸角度為120.5°,ODS自組裝膜擁有最佳之透光率91.12%,且抗菌藥劑濃度增加能夠增加表面清潔度,但接觸角度有降低的現象,TEOS50%抗菌混合膜擁有高接觸角度120.5°,也擁有較佳透光率。65.77%


Due to different surface properties, functional thin film, such as hydrophobic film, antimicrobial property film, wear resistance film, etc., is widely used in different situations. The self-assembled monomolecular film has hydrophobic properties, which can effectively reduce the adhesion property of the material’s surface through a simple production method, and can be extensively used in biomedical material, optic, electronic, machinery, micro-electro-mechanical engineering and other fields.
It is built in a mixed self-assembled molecular thin film technology, The mixed antimicrobial of the self-assembly film of the organosilane is used to adhere it onto the optics lens,, and then use the Taguchi method Exposure the highest rate of target angles, different soaking temperature, drying temperature, concentration and immersion time of the drug experimental parameters mixed self-assembled molecular thin film optical lenses, to get their films, the best mix of self-assembled molecular assembly OTS layer membrane contact surface cleanliness angle 106.3 °, 103.3 ° OTS10% antibacterial composite film, OTS50% antibacterial composite membrane 99.7 °, 102.1 ° ODS self-assembled monolayer 109 °, ODS10% antibacterial composite film, anti-bacterial film hybrid ODS50% 96.1 °, Staphylococcus aureus cocci antibacterial test, just add% (by weight) concentration of 10%, with excellent antibacterial effect, anti-bacterial. TEOS further mixed to obtain a higher membrane surface to obtain a pharmaceutical composition consisting of a film of adsorbed molecules prerequisite factor improvement control of the film composition in the case, to obtain a high contact angle and the surface contact ODS high cleanliness angle, TEOS contact angle contact angle of 137.8 °, hybrid membrane contact angle 130.5 TEOS10% antimicrobial, antibacterial TEOS50, hybrid membrane contact angle of 120.5 °, the best self-assembled monolayer optical transmittance 91.12%% , increasing concentrations of antimicrobial agent, can improve the surface cleanliness of the mixed bacterial membrane, but in the high contact angle, the contact angle of 120.5 ° to reduce TEOS50%, and has a good light transmission. 65.77%


目錄
摘要.......................................................i
Abstract.................................................iii
誌謝.......................................................v
目錄......................................................vi
表目錄...................................................viii
圖目錄.....................................................ix
符號說明..................................................xvi
第一章 緒論................................................1
1.1 前言...................................................1
1.2 研究背景與動機 ...........................................1
1.3 論文架構................................................2
第二章 文獻回顧與理論基礎.....................................4
2.1 有機單分子薄膜簡介........................................4
2.1.1 Langmuir-Blodgett薄膜簡介(LB薄膜)......................4
2.1.2 Self-assembled Monolayers薄膜簡介.....................5
2.2 有機矽烷自組裝薄膜的簡介...................................7
2.3 自組裝薄膜的磨潤性能、機械性質與抗菌功能......................9
2.4 黏附力的簡介............................................11
2.5 溶膠凝膠法簡介..........................................12
2.6 田口實驗方法簡介.........................................13
2.6.1 田口品質特性..........................................13
2.6.2 田口直交表...........................................13
2.6.3 田口實驗方法實施步驟...................................14
第三章 實驗規劃與實驗設備....................................21
3.1 實驗規劃...............................................21
3.2 自組裝單分子薄膜製作程序..................................22
3.2.1 實驗藥劑與基材........................................22
3.2.2自組裝混合分子薄膜製作程序...............................23
3.3 實驗設備...............................................25
3.3.1 接觸角量測儀(Contact Angle Measurement)...............25
3.3.2 原子力顯微鏡(Atomic Force Microscope).................26
3.3.3 電漿清洗機(Plasma Cleaner)...........................30
3.3.4 化學分析電子光譜儀(ESCA)...............................31
第四章 實驗結果分析與討論....................................41
4.1 田口實驗方法進行自組裝混合分子薄膜實驗.......................41
4.2 熔膠凝膠法於玻璃試片上進行表面改質..........................48
4.2 各自組裝薄膜接觸角與透光率的關係............................51
第五章 結論與未來展望.......................................80
5.1 結論..................................................80
5.2 未來展望...............................................81
簡 歷.....................................................97



[1] E. M. Mark, M. R. K. Krishna, T. Michael, (1994) “Role of Solvent on the Silanization of Glass with Octadecyltrichlorosilane,” Langmuir, 10, pp. 3607-3614.
[2] W. C. Bigelow, D. L. Pickett, W. A. Zisman, (1946) “Oleophobic Monolayers I. Films Adsorbed From Solution in Non-Polar Liquids,” J.Colloid Interface, Sci. 13, pp. 513-538.
[3] A. Pockels, (1981) “Prof Van der Wals on the Continuity of the Liquid and Gaseous states,” Nature, 43, pp. 437-439.
[4] A. Pockels,(1982) “On the Relative Contamination of the Water-Surface by Equal Quantities of Different Substances,” Nature, 46, pp. 418-419.
[5] I. Langmuir, (1917) “The Constitution and Fundamental Properties of Solids and Liquids,” J. Am. Chem., Soc. 39, pp. 1848-1906.
[6] I. Langmuir, (1920) “The Mechanism of the Surface Phenomena of Flotation,” Trans. Faraday, Soc. 15, pp. 62-74.
[7] W. C. Bigelow, D. L. Pickett, W. A. Zisman, (1946) “The Study of Reorganization of Self-Assembled Monolayers and Topochemical Photopolymerization ”, Collid Interface, Sci. 1, 513.
[8] H. Sellers, A. Ulman, Y. Shnidman, J. E. Eilers, (1993) “Structure and Bonding of Alkanethiolates on Gold and Silver surfaces: Implications for Self-Assembled Monolayers” Journal of the American Chemical Society, 115 pp. 9389-9401.
[9] 張立德,牟季美, (2002)「奈米結構自組織和分子自組織合成和性能」滄海書局 pp. 349.
[10] A. Ulman, (1991) “An Introduction to Ultrathin Organic Films From Langmuir-Blodgett to Self-Assembly” Rochester.
[11] J. Sagiv, J. Am. Chem, (1980) “Organized Monolayers by Adsorption. I. Formation and Structure of Oleophobic Mixed Monolayers on Solid Surfaces,” Soc. 102, pp. 92-98.
[12] R. G. Nuzzo, D. L. Allara, J. Am. Chem, (1983) “Adsorption of bifunctional organic disulfides on gold surfaces”, Soc. 105, pp. 4481-4483.
[13]P . Fenter, A . Eberhardt, P .Eisenberger, (1994) “Self-Assembly of n-Alkyl Thiols as Disulfides on Au”, Science.
[14]A. Ulman, (1991) “An Introduction to Ultrathin Organic Films From Langmuir-Blodgett to Self-Assembly,” Academic Press.
[15] A. L. David, (1995) “Critical issues in application of Aelf-Assemble Monolayers, ” Biosensors and Bioelectronics, 10, pp. 771-783.
[16] A. Ulman, (1996) “Formation and Structure of Self-Assmbled Monplayers,” Chem. Rev., 96, pp. 1533-1544.
[17]G. Steve, R. K. Carl, (1991) “Formation and Characterization of a highly Ordered and well-anchored Alkylsilsne Monolayer on Mica by Self-Assmbled,” Langmuir, 7, pp. 532-538.
[18] A. Kudelski, (2003) “Chemisorption of 2-Mercaptoethanol on Silver, Copper, and Gold: Direct Raman Evidence of Acid-InducedChanges in Adsorption/Desorption Equilibria”, Langmuir, 19, pp. 3805-3813.
[19] A. Kudelski, (2002) “Raman study on the structure of 3-mercaptopropionic acid monolayers on the silver”, Surface Science, 502~503, pp. 219-223.
[20] H. Hagenstrom, M. A. Schneeweiss and D. M. Kolb, (1999) “Modification of a Au(111) Electrode with Ethanethiol. 2. Copper Electrodeposition”, Langmuir, 15, pp7802-7809.
[21]J. Sagiv, (1980) “Organized Monolayers by Adsorption I. Formation and Structure of Oleophobic Mixed Monolayers on Solid Surfaces” , J.Am. Chem. Soc. 102, pp. 92-98.
[22]P. Silberzan, L. leger, D. Auserre, J. J. Benatter, (1991) “Silanation of Silica Surfaces . A New Method of Constructing Pure or Mixed Monolayers”, Langmuir, 7, pp. 1647-1651.
[23] K. Bierbaum, M. Grunze, A. A. Baski, L. F. Chi, W. Schrepp, H. Fuchs, (1995) “Growth of Self-Assembled N-Alkyltrichlorosilane Films on Si(100) Investigated by Atomic Force Microspcopy”, Langmuir, 11, pp. 2143-2150.
[24]T. Vallant, (1998) “Formation of Self-Assembled Octadecylsiloxane Monolayers on Mica and Silicon Surfaces Studied by Atomic Force Microscopy and Infrared Spectroscopy”, J. Phys. Chem. B. 102, pp. 7190-7197.
[25] S. R. Resch, et al., (1999) “In Situ and Ex Situ AFM Investigation of the Formation of Octadecylsiloxane Monolayer”, Appl. Surface Sci., pp. 168-175.
[26]C. Carraro, O. W. Yauw, M. M. Sung, R. Maboudian, (1998) “Observation of Three Growth Mechanisms in Self-Assemble Monolayers”, J. Phys. Chem. B. 102, pp. 4441-4445.
[27]S. Hiroyuki, H. Atsushi, K. Tetsuya and T. Osamu, (2002) “Organosilane Self-Assembled Monolayers Formed at the Vapor/Soild Interface,” Surface and Interface Analtsis, 34, pp. 550-554.
[28] Miki Nakano, Takao Ishida, Hikaru Sano, Hiroyuki Sugimura, Koji Miyake, Yasuhisa Ando, Shinya Sasaki, (2008) “Tribological properties of self-assembled monolayers covalently bonded to Si”, Applied Surface Science, 255, pp. 3040-3045.
[29] N. Rozlosnik, M. C. Gerstenberg, and N. B. Larsen, (2003) “Effect of Solvents and Concentration on the Formation of a Self-Assembled Monolayer of Octadecylsiloxane on Silicon(001),” Langmuir, 19, pp. 1182-1188.
[30]N. Kumar, C. Maldarelli, C. Steiner, A. Couzis, (2001) “Formation of Namometer Domains of One Chemical Functionality in a Continuous Matrix of a Second Chemical Functionality by Sequential Adsorption of Silane Self-Assembles Monolayers”, Langmuir ,17, pp. 7789-7797.
[31]C. M. Knobler, D. K. Schwartz, (1999) “Langmuir and Self-Assemble Monolayers”, Current Opinior in Colloid and Interface, Sci. 4, pp. 46-51.
[32]A. Tillman, A. Rlman, J. S. Schildkraut, (1988) “Incorporation of phenoxy Groups in Self-Assemble Monolayers of Trichlorosilane Derivatives. Effects on film Thickness, Wettability, and Molecular Orientation”, J. Am.Chem. Soc. 110, pp. 6136-6144.
[33]N. L. Jeon, K. Finnie, K. Branshaw, R. G. Nuzzo, (1997) “Structure and Stability of Patterned Self-Assemble Flims of Octadecylltrichlorosilane Formed by Contact Printing”, Langmuir, 13, pp. 3382-3391.
[34]P. John, M. S. Hildegard, G. Steve, R. K. Carl, (1995) “Self-Assemble Monolayers on Mica for Experiments Utilizing the Surface Forces Apparatus”, Langmuir, 11, pp. 953-962.
[35]S. S. Cheng, D. A. Scherson, C. N. Sukenik, J. Am. Chem, (1992) “In Situ Observation of Monolayer Self-Assembly by FTIR/ATR”, Journal of America Chemistry Society.114, pp. 5436-5437.
[36] Huiwen Liu, Bharat Bhushan, (2002) “Investigation of nanotribological properties of self-assembled monolayers with alkyl and biphenyl spacer chains (Invited)”, Ultramicroscopy, 91, pp. 185-205.
[37]B. Bhushan, T. Kasai, G. Kulik, L. Barbieri, P. Hoffmann, (2005) “AFM Study of Perfluoroalkylsilane and Alkylsilane Self-Assembled Monlayers for Anti-Stiction in MEMS/NEMS”, Ultramicroscopy, 105, pp. 176-188.
[38]N. S. Tambe, B. Bhushan, (2005) “Friction model for the velocity dependence of nanoscale friction”, Nanotechnology, 16, pp. 2309-2324.
[39]B. V. Derjaguin, V. M. Muller, and Y. P. Toporov, (1975) “Effect of Conact Deformation on the Adhesion of particles,” J. Colloidal Interface Sci., 53, pp. 314-326.
[40]A. Lio, D. H. Charych, M. Salmeron, (1997) “Comparative Atomic Force Microscopy Study of the Chain Length Dependence of Frictional Properties of Alkanethiol on Gold and Alkylsilanes on Mica”, J. Phys. Chem. B, 101, pp. 3800-3805.
[41]M. T. McDermott, JBD. Green, M. D. Porter, (1997) “Scanning Froce Microscopic Exploration of the Lubrication Capabilities of n-Alkanethiolate Monolayers Chemisorbed at Gold: Structural Basis of Microscopic Friction and Wear”, Langmuir, 13, pp. 2504-2510.
[42] Y. F. Dufrene, G. U. Lee, (2000) “Advances in the characterization of supported lipid films with the atomic force microscope Biochimica et Biophysica Acta (BBA) - Biomembranes,” Issues 1-2 ,1509, pp. 14-41, 20 December.
[43]V. Ganesh, V. Lakshminarayanan, (2006) “Self-Assembled Monolayers of Alkanethiols on Gold Prepared in a Hexagonal Lyotropic Liquid Crystalline Phase of Triton X-100/Water System ,Langmuir, 22 pp. 1561-1570.
[44]Nelson Torres, Sunho Oh, Mark Appleford, David D. Dean, James H. Jorgensen, Joo L. ong, C. Mauli Agrawal, Gopinath Mani, (2010) “Stability of antibacterial self-assembled monolayers on hydroxyapatite”, Acta Biomaterialia, 6, pp. 3242-3255.
[45]Weiyong Yuan, Jinhong Fu, Kai Su, Jian Ji, (2010) “Self-assembled chitosan/heparin multilayer film as a novel template for in situ synthesis of silver nanoparticles,” Colloids and Surfaces B: Biointerfaces, 76, pp. 549-555.
[46]Pascal Thebault, Elisabeth Taffin de Givenchy, Richard Levy, Yves Vandenberghe, Frederic Guittard, Serge Geribaldi, (2008) “Preparation and antimicrobial behaviour of quaternary ammonium thiol derivatives able to be grafted on metal surfaces,” European Journal of Medicinal Chemistry, 44, pp. 717-724.
[47]Pascal Thebault, Elisabeth Taffin de Givenchy, Richard Levy, Yves Vandenberghe, Frederic Guittard, Serge Geribaldi, (2009) “Contact-active microbicidal gold surfaces using immobilization of quaternary ammonium thiol derivatives,” European Journal of Medicinal Chemistry, 44, pp. 4227-4234.
[48]Pascal Thebault, Elisabeth Taffin de Givenchy, Richard Levy, Yves Vandenberghe, Frederic Guittard, Serge Geribaldi, (2010) “Surface and antimicrobial properties of semi-fluorinated quaternary ammonium thiol surfactants potentially usable for Self-Assembled Monolayers,” Journal of Fluorine Chemistry, 131, pp. 592-596.
[49] V. Ganesh, Santanu Kumar Pal, Sandeep Kumar, V. Lakshminarayanan, (2007) “Self-assembled monolayers (SAMs) of alkoxycyanobiphenyl thiols on gold surface using a lyotropic liquid crystalline medium,”Elec- trochimic Acta, 52, Issue 9, pp. 2987-2997.
[50]J. H. Horng, J. S. Lee and D. C. Du, (2006) “Three-Body Microcontact Model of Rough Surfaces and Its Application on Polishing of Wafer,” Material Science Forum, pp. 507-513.
[51]S. Biggs, and G. Spinks, (1998) “Atomic Force Microscopy Investigation of the Adhesion between a Single Polymer Sphere and a Flat Surface,” J.Adhes. Sci. Technol., 12, No.5, pp. 461-478.
[52] M. Reitsma, V. Craig, and S. Biggs, (2000) “Elasto-Plastic and Visco-Elastic Deformations of a Polymer Sphere Measured using Colloid Probe and Scanning Electron Microscopy,” J. Adhe. Adhes., 20, No.6, pp. 445-448.
[53]R. W. Carpick, and M. Salmeron, (1997) “Molecular dynamics study of dynamic contact and separation between tip and disk surface,” Chem. Rev. 97 pp. 1163.
[54]B. V. Derjaguin, V. M. Muller, and Y. P. Toporov, (1975) “Effect of Conact Deformation on the Adhesion of Elastic Solids,” J. Colloidal Interface Sci., 53, pp. 314-326.
[55]K. J. Johnson, K. Kendall, and A. D. Roberts, (1971) “Surface Energy and the Contact of Elastic Solids,” Proc. R. Soc. Lond , A324, pp. 301-313.
[56] D. Tabor, (1977) “Surface Forces and Surface Interactions,” J. Colloidal Interface Sci., 538, pp. 2-13.
[57] V. M. Muller, V. S. Yushchenko, and B. V. Derjaguin, (1980) “On the influence of Molecular Forces on the Deformation of an Elastic Sphere and its Sticking to Rigid Plane,” J. Colloidal Interface Sci., 77, pp. 91-101.
[58]W. R. Chang, I. Etsion, and D. B. Bogy, (1988) “Adhesion Model for Metallic Rough Surfaces,” ASME Journal of Tribology, 110, pp.50-56.
[59]D. Maugis, (1996) “On the Contact and Adhesion of Rough Surfaces,” J. Adhesion Sci., and Tech.,10, pp. 161-175.
[60]F. Aral, D. Ando, and T. Fukuda, (1996) “Adhesion Force Reduction for Micro Manipulation Base o n Micro Physic,” Proc, IEEE/RJS Int. Conf. On Intelligent Robotics and Systems, pp. 354-359.
[61]P. Sahoo, and S. K. Roy Chowdhury, (2000) “A fractal analysis of Adhesion Friction between Rough Solids in Gentle Sliding,” Poc. Instn. Mech. Engrs., 214, Part J, pp. 583-594.
[62]G. L. de Lange, C. De Putter, and F. L. J. A. De Wijs, (1990) ‘‘Histological and Ultra-Structural Appearance of the Hydroxyapatite-Bone Interface’’, J. Biomed. Mater. Res., 24.
[63]H. A. Hoogendoom, W. Renooij, L. M. A. Akkermans, W. Visser, and P. Wittebol, (1983) ‘‘Long-Term Study of Large Ceramic Implan (Porous Hydroxyaptite) in Dog femora’’, Clin. Orthop., 187 pp. 281-288.
[64]Jae-hyun Kim, Bo-hyun Lee, Hansaem Kang, Jaeyeal Kim, Geesung Chae, Inbyeong Kang, In-jae Chung, (2009) ‘‘Self-assembly of Ag nanopowder on OTS-patterned glass’’, Applied Surface Science, 255, pp. 9386-9390.
[65]H. Lin, H. Kozuka, T. Yoko, (1997) ‘‘Preparation of TiO2 films on self-assembled monolayers by sol-gel method’’, Thin Solid Films, 315, pp. 111-117.
[66]Shang-Ray Yang , Bernd O. Kolbesen, (2008) ‘‘A comparative study of the growth of octadecyltrichlorosilane and 3-mercaptopropyltrimethoxysilane self-assembled monolayers on hydrophilic silicon surfaces’’, Applied Surface Science, 255, pp. 1726-1735
[67]Gopinath Mani, Marc D. Feldman, Sunho Oh, C. Mauli Agrawal, (2009) ‘‘Surface modification of cobalt-chromium-tungsten-nickel alloy using octadecyltrichlorosilanes’’, Applied Surface Science, 255, pp. 5961-5970.
[68] Ebelmen (1846), Ueber die Erzeugung von durchsichtigem Kiesel und von Hydrophan. J. Prakt. Chem., 37: 58–59. doi: 10.1002/prac.
[69] R. Roy, Journal of the American Ceramic Society. 39, 145-146 (1956).
[70] H. Dislich and E. Hussmann, ngewandte Chemie International Edition. 10, 363-370 (1971).
[71] Nabi Aghdassi, Dorothea Dulson, Steffen Linden, Liqiang Li, Lifeng Chi, Helmut Zacharias. Very large-bandgap insulating monolayers of ODS on SiC (2012).
[72] Ismail Ab Rahman and Vejayakumaran Padavettan, Synthesis of Silica Nanoparticles by Sol-Gel: Size-Dependent Properties, Surface Modification, and Applications in Silica-Polymer Nanocomposites—A Review (2012).


QRCODE
 
 
 
 
 
                                                                                                                                                                                                                                                                                                                                                                                                               
第一頁 上一頁 下一頁 最後一頁 top
系統版面圖檔 系統版面圖檔