臺灣博碩士論文加值系統

記憶在人類認知歷程中是一項相當重要的功能，有關於alpha波神經回饋訓練增進記憶能力之議題已被廣泛地探討與應用，然而在已發表的alpha波訓練介面之記憶 成效有許多不一致，因此進一步探討alpha波訓練對記憶功能的影響是極具重要之議題。本研究利用本實驗室開發之神經回饋設置，進行特定腦區的alpha波能量增強訓練，並進行具多要求性的事件記憶能力之評估，同時利用腦波頻譜圖與功能性磁振造影來探討影響事件記憶表現之成因。經過3周共12次的alpha波神經回饋訓練後，結果顯示alpha波回饋組的事件記憶作業分數顯著高於隨機回饋組的表現，且在訓練後之alpha波能量主要分佈於額頂葉等區域，事件記憶作業正確率之增進與腦波能量的增強呈顯著的正相關。最後在功能性磁振造影的初步結果指出，alpha波訓練組於記憶再認測驗與進入誘發alpha波之情境時，均顯示預設模式網路的活性或連結性有顯著改變現象。因此，本研究證實額頂葉的alpha波訓練確實有助於事件記憶之促進，且此記憶增進似乎與大腦預設模式網路之調節有關。

Memory is always an interesting issue and plays an important role in the cognitive process. Numerous kinds of alpha neurofeedback trainings on memory performance have been widely studied over the past years. However, large inconsistencies, including the memory performance and training parameters, exist in the alpha neurofeedback trainings of previous studies. In the present study, a self-developed neurofeedback apparatus was sued to enhance the alpha power of particular brain areas. Episodic memory paradigm with more-demands was used. Electroencephalographic map and functional magnetic resonance imaging (fMRI) were used to assess possible clues on changes of episodic memory. After 12 sessions of alpha feedback trsainings within 3 weeks, the alpha neurofeedback group showed a significant higher accuracy in the episodic memory task compared to the control group receiving feedback of random frequency bandwidths. The alpha power was primarily elicted in the frontoparietal areas. Improvement of accuracy of the episodic memory task showed a significant positive correlation with the increment of alpha powers before and after the neurofeedback training. Preliminary results of the fMRI experiment revealed that blood-oxygen-level-detection activity or connectivity of the default mode network (DMN) were significantly altered during recognition phase of the episodic memory and alpha-reactivated mode in the alpha neurofeedback training group. Our results indicate that training of the frontoparietal alpha rhythm significantly enhance episodic memory. The enhancement of episodic memory in the alpha traing group may be related to alter the DMN modulation.

中文摘要 I
英文摘要 II
誌謝 III
目次 V
表次 VII
圖次 VIII
符號 XI
第一章 緒論 1
第一節 記憶的重要性 1
第二節 記憶的三項基本運作 1
第三節 記憶訓練的類別與實徵研究 2
第四節 Alpha節律與其訓練介面 7
第五節 先前研究之限制 10
第六節 研究目的與假設 12
第二章 研究方法 15
第一節 實驗一A 15
第二節 實驗一 20
第三節 實驗二 27
第四節 實驗三 32
第三章 研究結果 38
第一節 實驗一A結果 38
第二節 實驗一結果 39
第三節 實驗二結果 43
第四節 實驗三結果 46
第四章 討論 50
第五章 結論與未來展望 56
第一節 結論 56
第二節 未來展望 56
參考文獻 58
中文部分 58
英文部分 58
附錄 108
附錄一 功能性磁振造影－受測安全性問卷 108

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