臺灣博碩士論文加值系統

在科技進步的現代社會，近視已是日趨嚴重的公衛問題，不僅盛行率增加，發生年齡亦下降，其中又以華人社會最為嚴重。同時眼科醫學亦著力於近視的預防與治療。在近視眼的研究中，統計分析是不可或缺的角色。本論文整理了有助於近視研究的統計方法，內容包含：最常見的橫斷面研究，可找出近視的風險因子；利用分析長期追蹤資料，探討近視度數演進的變化。此外眼科測度為“成對”但彼此相關的資料，存活分析可以用來探討眼睛發生重要“事件” 所需的時間長度。我們亦回顧了台灣、新加坡及其他地區所發表有關於近視眼研究的醫學文獻，並整理這些論文使用的統計方法。最後我們以統計的角度，建議了未來研究可採用的方法。

Nowadays myopia has become a global critical health problem, especially in Chinese community. Statistical analysis plays an important role in myopia research. In the thesis, we investigate related statistical methods, including cross-sectional studies for identifying possible risk factors for myopia and longitudinal studies for studying the evolution of myopia. Eye measurements are “paired” observations so that we review methods for analyzing such data. Furthermore survival analysis can also be applied to study critical event times such as the onset of myopia. We also review medical literature on myopia, most of which are recent empirical studies in Taiwan and Singapore. At the end of the thesis, we provide some suggestions for future research from the viewpoint of statistical analysis.

Contents
中文摘要................................................................................................................ i
英文摘要...............................................................................................................ii
誌謝 ......................................................................................................................iii
Contents............................................................................................................... iv
Tables...................................................................................................................vi
Figures ................................................................................................................vii
1 Introduction ...................................................................................................... 1
1.1 Motivation......................................................................................................................... 1
1.2 Outline of the Thesis......................................................................................................... 2
2 Medical background on Myopia ..................................................................... 3
2.1 Introduction of Myopia - Medical Background................................................................ 3
3 Literature Review on Related Statistical Methods ....................................... 5
3.1 Methods for Cross-sectional Studies ................................................................................ 5
3.2 Methods for Longitudinal Studies .................................................................................... 8
3.3 Survival Analysis.............................................................................................................. 9
3.4 Methods for analyzing paired data ................................................................................. 14
4 Statistical Applications in Myopia Research............................................... 16
4.1 Myopia research in Taiwan ............................................................................................ 16
4.2 Myopia Research in Singapore....................................................................................... 17
4.3 Studying Risk Factors on Myopia of Different Severity................................................ 17
4.4 A Longitudinal Study for Predicting Myopia................................................................. 19
4.5 Myopia and other eye diseases ....................................................................................... 20
5 Our Suggestions on Statistical Analysis ....................................................... 21
References .......................................................................................................... 23
附錄 眼科醫學名詞之中譯............................................................................. 25

References
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