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研究生:吳直晏
研究生(外文):Wu Chih Yen
論文名稱:醫療磁熱針感磁特性研究分析
論文名稱(外文):Study on Induction Heating Characteristics of Medical Hyperthermia Magnetic Needles
指導教授:蔡昆宏蔡昆宏引用關係張益三張益三引用關係
指導教授(外文):Kuen-Horng TsaiYi-San Chang
口試委員:許瑞廷尤崇智
口試委員(外文):Jui-Ting HsuTsung-Chih Yu
口試日期:2014-08-13
學位類別:碩士
校院名稱:國立臺南大學
系所名稱:機電系統工程研究所
學門:工程學門
學類:機械工程學類
論文種類:學術論文
論文出版年:2014
畢業學年度:102
語文別:中文
論文頁數:81
中文關鍵詞:感磁針具中高週波加熱器感應線圈
外文關鍵詞:Induction magnetic needleHigh frequency inductive heaterInduction coil.
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惡性腫瘤一直是目前國人十大死因之首,治療腫瘤方法許多種,熱消融為其中一種,此療法透過感應加熱器於體外產生交變磁場,利用渦電流,感應加熱在病灶中的感磁針具,使針具溫度上升至足以殺死腫瘤細胞之溫度,以達到熱療效果。影響感磁熱療燒灼法的因素有相當多種,本論文在此提出三個關鍵因素,感應線圈大小與位置、感應加熱器的輸出功率、針具設計。
本研究主要目的是透過實驗找出適合於應用在甲狀腺的感磁針具(臨床規格10 mm感磁部),並針對感磁部的材料,以及在不同的直徑感應線圈和不同的輸出功率中尋找殺死腫瘤細胞溫度的最佳條件。
四種不銹鋼材質的實驗結果,以SUS630升溫效果最好,故以此材質設計為感磁針具。總結,針具在三種不同線圈中心時,熱融溫度最佳條件為:輸出功率≧60%,感應線圈≦ø100mm。針具在三種不同線圈內側邊緣時,熱融溫度最佳條件為: 40%~60%為最佳的輸出功率(40%時使用≦ø200mm感應線圈,60%時使用≧ø300mm感應線圈)。
感磁針具溫度分析屬於基礎研究,透過實驗找到適合的針具材質,並且在實驗中觀察感磁針具溫度反應的特性,經過數據的分析,往後針具材料選擇、設計和手術上所需要條件都能獲得改善。

Malignancies currently have been the first of the ten leading causes of death. There are many types of cancer treatment methods, and one of them is the thermal ablation. This treatment method involves the use of an induction heater to generate into vitro high-frequency alternating magnetic field. Through an eddy current, induction heating is performed using treatment needles inserted into lesions. The heating process enables the needles to reach temperatures sufficient for killing tumor cells and thus achieving effective thermotherapy. There are a lot of factors affecting electromagnetic thermotherapy, but we just propose three key factors in this thesis, which are the size and position of induction coil, the output power of induction heater and the needle design.
The main purpose of this study is to find out a suitable magnetic needle for the thyroid treatment through the experiments (10mm magnetic part in clinical specifications), and through the magnetic material, the different Diameter induction coil and the output power to identify the optimal temperature condition to kill tumor cells.
In conclusion, the experimental results indicated that SUS630 material, which is the best heating effect of four kinds of stainless steel, is designed to the magnetic needle. When the needle places in the center of three different coils, the optimal conditions of melt temperature are Output power≧60% and Induction coil≦ø100mm. Nevertheless, when the needle places at the outside of coils, the optimal condition of melt temperature is during 40%-60% Output power (While Output power is 40%, it is better to use ≦ø200mm of Induction coil. However, while Output power is 60%, it is better to use ≧ø300mm of Induction coil.)
The temperature analysis of magnetic needle is a fundamental research. Through the experiments, we found a suitable needle material and observed the characteristics of temperature reaction for the magnetic needle. In addition, through the data analysis, it can be improved on the needle material selection and design, and all conditions requirement on surgery in the future.

目錄
中文摘要
英文摘要
誌謝
目錄
表目錄
圖目錄
第一章緒論
第一節甲狀腺腫瘤治療方法基本介紹
第二節感應加熱的理論背景及基本介紹
第三節研究目的
第四節論文架構
第二章研究方法
第一節評估溫度分析
第二節實驗環境、儀器及檢測設備
第三節實驗流程
第三章研究結果
第一節金屬圓棒溫度測量結果
一、輸出功率20%T1、T2溫度測量結果
二、輸出功率80%T1、T2溫度測量結果
三、輸出功率80%T1、T2溫度測量結果
第二節感磁熱療針測量結果
一、感應線圈中心溫度測量結果(21G感磁部10mm)
二、感應線圈內側邊緣溫度測量結果(21G感磁部10mm)
第四章討論
第一節四種不同材料金屬圓棒溫度變化
第二節21G感磁熱療針在不同線圈與輸出功率溫度變化
一、感應線圈中心T1、T2處溫度變化
二、感應線圈內側邊緣T1、T2處溫度變化
第五章結論
第一節總述
第二節未來方向
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