臺灣博碩士論文加值系統

一般而言，身體健康的評估，必須經由多面向的評估指標完成；其中，肢體活動度與受測者的日常生活便利性，具有直接的關聯。提升肢體活動度的方式，包括靜態拉伸與動態拉伸，透過拉伸運動可以增加肌肉的伸展性，並藉此改善關節活動度。目前，肌肉柔軟度評估的相關研究較少見，相對地，因靜態生活方式造成的肩頸僵硬或疼痛是近年的研究重點，其中，肌肉血流生理參數是該項量測中重要的評估依據。因此，本研究使用非侵入式高功率雷射都卜勒血流計，量測小腿肌肉在伸展與放鬆運動時的血液灌流訊號並分析，進而開發可應用於評估肌肉柔軟度的微循環指標系統。
參與本研究之個案共計18位，年齡介於20至21歲之間，且下肢健康的大學生，以足踝背屈的活動度定義小腿的柔軟度，分為高柔軟度組與低柔軟度組，每名個案參與連續六個階段小腿肌肉伸展與放鬆交互的實驗，同時量測小腿肌腹表面之微循環血流量的變化，測得的雷射都卜勒血流訊號經自行開發的訊號分析程式，換算出直流、交流與交直流比三個局部組織灌流參數。結果顯示，與低柔軟度組相較，高柔軟度組的Flux dc參數與Flux ac參數在小腿肌肉拉伸與放鬆階段，具有較高的穩定度；高柔軟度組在六個階段中的Flux pp參數，都較低柔軟度組為高。量測拉伸運動下的微循環血流穩定度，可以提供局部柔軟度的定量指標，彈性越佳的部位，越不會因為運動姿勢或型態，造成微循環血流供應下降的情況。未來，本研究可以應用於運動醫學治療成效評估，以達到預防醫療的目的。

Generally speaking, the evaluation of good health is completed from multi-dimensional evaluation indicators, in which the range of physical motion and the daily living convenience of participants present the most direct correlations. The promotion of the range of physical motion contains static stretching and dynamic stretching that the muscular extensibility could be enhanced through stretching exercises so as to improve the range of joint motion. Currently, the research on the evaluation of muscular flexibility is rare; however, the research on stiff neck or pain caused by static living styles has been the key in the past years, where the measurement of physiological parameters of muscle blood flow is the primary evaluation reference. In this case, a non-invasive high-power laser Doppler blood flowmeter is utilized for measuring and analyzing the hemoperfusion signals when calf muscles are preceded stretching and relaxation exercises to develop a microcirculation indicator system applicable to evaluating muscle flexibility.
Total 18 college students, aged 20-21 with healthy lower extremity, participate in the study. The range of ankle dorsiflexion motion is used for defining the calf flexibility, which is divided into the high flexibility group and the low flexibility group. Each participant joins in six-stage calf muscle stretching and relaxation experiments and measured the microcirculation blood flow changes of the calf gastrocnemius muscles. The measured laser Doppler blood flow signals are converted into three local tissue perfusion parameters of direct-current, alternate-current, and alternating/direct-current ratio with self-developed signal analysis program. The results show that the Flux dc and Flux ac parameters of the high flexibility group present higher stability at the calf muscle stretching and relaxation stage than those of the low flexibility group; and, the Flux pp of the high flexibility group at six stages is higher than it of the low flexibility group. The measurement of microcirculation blood flow stability under stretching exercises could provide the quantitative indicator of local flexibility that the parts with better flexibility would not appear decreasing microcirculation blood flow because of exercise postures or patterns. This study could be applied to the evaluation of sports medicine therapeutic effect so as to achieve the objective of preventive medicine in the future.

摘要 III
Abstract IV
目錄 VI
圖目錄 IX
表目錄 XII
第一章 緒論 1
1.1 前言 1
1.2 研究動機與目的 3
1.3 文獻回顧 4
1.4 論文架構 6
第二章 系統原理 7
2.1 微循環介紹 7
2.2 心電圖量測方法及原理 9
2.3 光體積變化描述血液量測方法及原理 11
2.4 雷射都卜勒血流量測方法及原理 13
2.5 雷射都卜勒與光體積變化描述方法比較 17
2.6 Matlab程式軟體介紹 18
第三章 系統實現 19
3.1 系統架構 19
3.2 雷射都卜勒儀器 19
3.3 心電圖 22
3.3.1 儀表放大器 23
3.3.2 高通濾波器 24
3.3.3 低通濾波器 26
3.3.4 右腳驅動電路 27
3.4 訊號擷取系統 28
3.4.1 數位類比訊號 28
3.4.2 實驗設備USB-6221 DAQcard 30
3.5 量測與分析系統 31
3.5.1 使用者操作介面 31
3.5.2 訊號分析 34
第四章 臨床應用實例 37
4.1 實驗設計 37
4.1.1 量測對象 37
4.1.2 實驗設計 37
4.2 統計分析 40
4.3 兩組基本生理參數比較 40
4.4 兩組微循環血流訊號比較 41
4.4.1 血流參數部分 41
4.4.2 血流波形部分 44
4.4.3 討論 47
第五章 結論與未來工作 48
5.1 結論 48
5.2 未來工作 49
參考文獻 50

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