|
1. Sammet, B., C. Steinkuhler, and N. Sewald. 2012. Antibody-drug conjugates in tumor therapy. Pharmaceutical patent analyst 1: 65-73. 2. Stagg, J., U. Divisekera, N. McLaughlin, J. Sharkey, S. Pommey, D. Denoyer, K. M. Dwyer, and M. J. Smyth. 2010. Anti-CD73 antibody therapy inhibits breast tumor growth and metastasis. Proceedings of the National Academy of Sciences of the United States of America 107: 1547-1552. 3. Kasuya, K., Y. Nagakawa, M. Suzuki, H. Tanaka, H. Ohta, T. Itoi, and A. Tsuchida. 2011. Anti-vascular endothelial growth factor antibody single therapy for pancreatic neuroendocrine carcinoma exhibits a marked tumor growth-inhibitory effect. Experimental and therapeutic medicine 2: 1047-1052. 4. Emery, P., R. M. Fleischmann, L. W. Moreland, E. C. Hsia, I. Strusberg, P. Durez, P. Nash, E. J. Amante, M. Churchill, W. Park, B. A. Pons-Estel, M. K. Doyle, S. Visvanathan, W. Xu, and M. U. Rahman. 2009. Golimumab, a human anti-tumor necrosis factor alpha monoclonal antibody, injected subcutaneously every four weeks in methotrexate-naive patients with active rheumatoid arthritis: twenty-four-week results of a phase III, multicenter, randomized, double-blind, placebo-controlled study of golimumab before methotrexate as first-line therapy for early-onset rheumatoid arthritis. Arthritis and rheumatism 60: 2272-2283. 5. Willemsen, R., P. Chames, E. Schooten, J. W. Gratama, and R. Debets. 2008. Selection of human antibody fragments directed against tumor T-cell epitopes for adoptive T-cell therapy. Cytometry. Part A : the journal of the International Society for Analytical Cytology 73: 1093-1099. 6. Rauschert, N., S. Brandlein, E. Holzinger, F. Hensel, H. K. Muller-Hermelink, and H. P. Vollmers. 2008. A new tumor-specific variant of GRP78 as target for antibody-based therapy. Laboratory investigation; a journal of technical methods and pathology 88: 375-386. 7. Rutella, S., and F. Locatelli. 2012. Is there a role for cytokine-induced killer cells in cancer immunotherapy? Immunotherapy 4: 867-869. 8. Li, R., C. Wang, L. Liu, C. Du, S. Cao, J. Yu, S. E. Wang, X. Hao, X. Ren, and H. Li. 2012. Autologous cytokine-induced killer cell immunotherapy in lung cancer: a phase II clinical study. Cancer immunology, immunotherapy : CII 61: 2125-2133. 9. Thanendrarajan, S., M. Nowak, H. Abken, and I. G. Schmidt-Wolf. 2011. Combining cytokine-induced killer cells with vaccination in cancer immunotherapy: more than one plus one? Leukemia research 35: 1136-1142. 10. Sarkar, D., P. Dent, D. T. Curiel, and P. B. Fisher. 2008. Acquired and innate resistance to the cancer-specific apoptosis-inducing cytokine, mda-7/IL-24: not insurmountable therapeutic problems. Cancer biology &; therapy 7: 109-112. 11. Lin, W. W., and M. Karin. 2007. A cytokine-mediated link between innate immunity, inflammation, and cancer. The Journal of clinical investigation 117: 1175-1183. 12. Quan, L., Z. Gong, S. Yao, E. V. Bandera, G. Zirpoli, H. Hwang, M. Roberts, G. Ciupak, W. Davis, L. Sucheston, K. Pawlish, D. H. Bovbjerg, L. Jandorf, C. Cabasag, J. G. Coignet, C. B. Ambrosone, and C. C. Hong. 2013. Cytokine and cytokine receptor genes of adaptive immune response are differentially associated with breast cancer risk in American women of African and European ancestry. International journal of cancer. Journal international du cancer. 13. Zhang, R. X., B. Liu, A. Li, L. Wang, K. Ren, J. T. Qiao, B. M. Berman, and L. Lao. 2008. Interleukin 1beta facilitates bone cancer pain in rats by enhancing NMDA receptor NR-1 subunit phosphorylation. Neuroscience 154: 1533-1538. 14. Premkumar, V. G., S. Yuvaraj, K. Vijayasarathy, S. G. Gangadaran, and P. Sachdanandam. 2007. Serum cytokine levels of interleukin-1beta, -6, -8, tumour necrosis factor-alpha and vascular endothelial growth factor in breast cancer patients treated with tamoxifen and supplemented with co-enzyme Q(10), riboflavin and niacin. Basic &; clinical pharmacology &; toxicology 100: 387-391. 15. Angst, E., H. A. Reber, O. J. Hines, and G. Eibl. 2008. Mononuclear cell-derived interleukin-1 beta confers chemoresistance in pancreatic cancer cells by upregulation of cyclooxygenase-2. Surgery 144: 57-65. 16. Gershanovich, M. L., L. V. Filatova, S. A. Ketlinsky, and A. S. Simbirtsev. 2001. Recombinant human interleukin-1 beta: new possibilities for the prophylaxis and correction of toxic myelodepression in patients with malignant tumors. II. Phase II study of the protective effect of recombinant human interleukin-1 beta on myelodepression induced by chemotherapy in cancer patients. European cytokine network 12: 671-675. 17. Carmona, L. 2010. [Anti-TNF therapy and cancer]. Reumatologia clinica 6: 102-105. 18. Burton, E. R., and S. K. Libutti. 2009. Targeting TNF-alpha for cancer therapy. Journal of biology 8: 85. 19. Lejeune, F. J., D. Lienard, M. Matter, and C. Ruegg. 2006. Efficiency of recombinant human TNF in human cancer therapy. Cancer immunity 6: 6. 20. Leist, M., and M. Jaattela. 2002. Burning up TNF toxicity for cancer therapy. Nature medicine 8: 667-668. 21. Del Monte, G., P. Ferroni, S. Mariotti, E. Fossile, F. Guadagni, and M. Roselli. 2008. Interleukin-2 inhalation therapy in renal cell cancer: a case report and review of the literature. In vivo 22: 481-488. 22. Eklund, J. W., and T. M. Kuzel. 2004. A review of recent findings involving interleukin-2-based cancer therapy. Current opinion in oncology 16: 542-546. 23. Nagao, Y., Y. Hiromatsu, T. Nakashima, and M. Sata. 2008. Graves' ophthalmopathy and tongue cancer complicated by peg-interferon alpha-2b and ribavirin therapy for chronic hepatitis C: A case report and review of the literature. Mol Med Rep 1: 625-631. 24. Mouallif, M., H. L. Bowyer, S. Festali, A. Albert, Y. Filali-Zegzouti, S. Guenin, P. Delvenne, J. Waller, and M. M. Ennaji. 2014. Cervical cancer and HPV: Awareness and vaccine acceptability among parents in Morocco. Vaccine 32: 409-416. 25. Osazuwa-Peters, N. 2013. Human papillomavirus (HPV), HPV-associated oropharyngeal cancer, and HPV vaccine in the United States--do we need a broader vaccine policy? Vaccine 31: 5500-5505. 26. Sagar, M., and A. K. Yadav. 2011. Computer-aided vaccine design for liver cancer using epitopes of HBx protein isolates from HBV substrains. International journal of bioinformatics research and applications 7: 299-316. 27. Jenkins, D. 2008. A review of cross-protection against oncogenic HPV by an HPV-16/18 AS04-adjuvanted cervical cancer vaccine: importance of virological and clinical endpoints and implications for mass vaccination in cervical cancer prevention. Gynecologic oncology 110: S18-25. 28. Fox, J. L. 2007. Uncertainty surrounds cancer vaccine review at FDA. Nature biotechnology 25: 827-828. 29. Nemunaitis, J., and J. Nemunaitis. 2007. A review of vaccine clinical trials for non-small cell lung cancer. Expert opinion on biological therapy 7: 89-102. 30. Gardner, T. A., B. D. Elzey, and N. M. Hahn. 2012. Sipuleucel-T (Provenge) autologous vaccine approved for treatment of men with asymptomatic or minimally symptomatic castrate-resistant metastatic prostate cancer. Human vaccines &; immunotherapeutics 8: 534-539. 31. Cheever, M. A., and C. S. Higano. 2011. PROVENGE (Sipuleucel-T) in prostate cancer: the first FDA-approved therapeutic cancer vaccine. Clinical cancer research : an official journal of the American Association for Cancer Research 17: 3520-3526. 32. Fujiwara, H. 2013. Adoptive T-cell therapy for hematological malignancies using T cells gene-modified to express tumor antigen-specific receptors. International journal of hematology. 33. Ochi, T., H. Fujiwara, and M. Yasukawa. 2010. Application of adoptive T-cell therapy using tumor antigen-specific T-cell receptor gene transfer for the treatment of human leukemia. Journal of biomedicine &; biotechnology 2010: 521248. 34. Denmeade, S. R., A. M. Mhaka, D. M. Rosen, W. N. Brennen, S. Dalrymple, I. Dach, C. Olesen, B. Gurel, A. M. Demarzo, G. Wilding, M. A. Carducci, C. A. Dionne, J. V. Moller, P. Nissen, S. B. Christensen, and J. T. Isaacs. 2012. Engineering a prostate-specific membrane antigen-activated tumor endothelial cell prodrug for cancer therapy. Science translational medicine 4: 140ra186. 35. Ogura, M., T. Shibata, H. Harada, and M. Hiraoka. 2006. [Tumor-specific gene therapy strategy for renal cell carcinomas]. Nihon rinsho. Japanese journal of clinical medicine 64 Suppl 2: 672-675. 36. Haenssle, H. A. 2005. Vaccination therapy with tumor-dendritic cell hybrids: a promising therapeutic approach? Curr Opin Investig Drugs 6: 1240-1245. 37. Katano, M., T. Morisaki, K. Koga, M. Nakamura, H. Onishi, K. Matsumoto, A. Tasaki, H. Nakashima, T. Akiyoshi, and M. Nakamura. 2005. Combination therapy with tumor cell-pulsed dendritic cells and activated lymphocytes for patients with disseminated carcinomas. Anticancer research 25: 3771-3776. 38. Pioche, C., B. Salomon, and D. Klatzmann. 1995. [Dendritic cells and tumor cell therapy]. Pathologie-biologie 43: 904-909. 39. Van Gool, S., and S. De Vleeschouwer. 2012. Should dendritic cell-based tumor vaccination be incorporated into standard therapy for newly diagnosed glioblastoma patients? Expert review of neurotherapeutics 12: 1173-1176. 40. Onishi, H., T. Morisaki, E. Baba, M. Nakamura, S. Inaba, H. Kuroki, K. Matsumoto, and M. Katano. 2011. Long-term vaccine therapy with autologous whole tumor cell-pulsed dendritic cells for a patient with recurrent rectal carcinoma. Anticancer research 31: 3995-4005. 41. Berhanu, A., J. Huang, S. M. Alber, S. C. Watkins, and W. J. Storkus. 2006. Combinational FLt3 ligand and granulocyte macrophage colony-stimulating factor treatment promotes enhanced tumor infiltration by dendritic cells and antitumor CD8(+) T-cell cross-priming but is ineffective as a therapy. Cancer research 66: 4895-4903. 42. Alderson, K. L., and P. M. Sondel. 2011. Clinical cancer therapy by NK cells via antibody-dependent cell-mediated cytotoxicity. Journal of biomedicine &; biotechnology 2011: 379123. 43. Cerwenka, A., C. S. Falk, and C. Watzl. 2007. NK cells--from basic research to cancer therapy. European journal of immunology 37: 1161-1164. 44. Suzuki, K., H. Nakazato, H. Matsui, M. Hasumi, Y. Shibata, K. Ito, Y. Fukabori, K. Kurokawa, and H. Yamanaka. 2001. NK cell-mediated anti-tumor immune response to human prostate cancer cell, PC-3: immunogene therapy using a highly secretable form of interleukin-15 gene transfer. Journal of leukocyte biology 69: 531-537. 45. Lundqvist, A., H. Yokoyama, A. Smith, M. Berg, and R. Childs. 2009. Bortezomib treatment and regulatory T-cell depletion enhance the antitumor effects of adoptively infused NK cells. Blood 113: 6120-6127. 46. Lee, J., C. Suh, H. J. Kang, B. Y. Ryoo, J. Huh, Y. H. Ko, H. S. Eom, K. Kim, K. Park, and W. S. Kim. 2008. Phase I study of proteasome inhibitor bortezomib plus CHOP in patients with advanced, aggressive T-cell or NK/T-cell lymphoma. Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 19: 2079-2083. 47. Shen, L., W. Y. Au, T. Guo, K. Y. Wong, M. L. Wong, J. Tsuchiyama, P. W. Yuen, Y. L. Kwong, R. H. Liang, and G. Srivastava. 2007. Proteasome inhibitor bortezomib-induced apoptosis in natural killer (NK)-cell leukemia and lymphoma: an in vitro and in vivo preclinical evaluation. Blood 110: 469-470. 48. Moncada, B., S. Sobrevilla-Ondarza, and J. D. Md. 2013. Radiotherapy supports a better outcome than chemotherapy in cutaneous natural killer (NK)/T cell lymphoma nasal type. International journal of dermatology 52: 1276-1277. 49. Rosental, B., M. Y. Appel, R. Yossef, U. Hadad, M. Brusilovsky, and A. Porgador. 2012. The effect of chemotherapy/radiotherapy on cancerous pattern recognition by NK cells. Current medicinal chemistry 19: 1780-1791. 50. Li, Y. X., H. Wang, J. Jin, W. H. Wang, Q. F. Liu, Y. W. Song, Z. Y. Wang, S. N. Qi, S. L. Wang, Y. P. Liu, X. F. Liu, and Z. H. Yu. 2012. Radiotherapy alone with curative intent in patients with stage I extranodal nasal-type NK/T-cell lymphoma. International journal of radiation oncology, biology, physics 82: 1809-1815. 51. Salagianni, M., E. Lekka, A. Moustaki, E. G. Iliopoulou, C. N. Baxevanis, M. Papamichail, and S. A. Perez. 2011. NK cell adoptive transfer combined with Ontak-mediated regulatory T cell elimination induces effective adaptive antitumor immune responses. J Immunol 186: 3327-3335. 52. Shortman, K., A. Wilson, J. Baker, and R. C. Burton. 1982. An NK-like cell limits the adoptive response from "pre-progenitor" B cells. The Australian journal of experimental biology and medical science 60: 581-592. 53. Meller, B., C. Frohn, J. M. Brand, I. Lauer, L. F. Schelper, K. von Hof, H. Kirchner, E. Richter, and M. Baehre. 2004. Monitoring of a new approach of immunotherapy with allogenic (111)In-labelled NK cells in patients with renal cell carcinoma. European journal of nuclear medicine and molecular imaging 31: 403-407. 54. Nissen, M. H., M. Jeppesen, and M. H. Claesson. 2000. Splenocytes cultured in low concentrations of IL-2 generate NK cell specificities toward syngenic and allogenic targets. Cellular immunology 203: 47-54. 55. Arnon, T. I., G. Markel, A. Bar-Ilan, J. Hanna, E. Fima, F. Benchetrit, R. Galili, A. Cerwenka, D. Benharroch, N. Sion-Vardy, A. Porgador, and O. Mandelboim. 2008. Harnessing soluble NK cell killer receptors for the generation of novel cancer immune therapy. PloS one 3: e2150. 56. Bubenik, J., J. Zeuthen, D. Bubenikova, J. Simova, and T. Jandlova. 1993. Gene therapy of cancer: use of IL-2 gene transfer and kinetics of local T and NK cell subsets. Anticancer research 13: 1457-1460. 57. Shaw, S. G., A. A. Maung, R. J. Steptoe, A. W. Thomson, and N. L. Vujanovic. 1998. Expansion of functional NK cells in multiple tissue compartments of mice treated with Flt3-ligand: implications for anti-cancer and anti-viral therapy. J Immunol 161: 2817-2824. 58. Ascierto, P. A., E. Simeone, M. Sznol, Y. X. Fu, and I. Melero. 2010. Clinical experiences with anti-CD137 and anti-PD1 therapeutic antibodies. Seminars in oncology 37: 508-516. 59. Weber, J. 2010. Immune checkpoint proteins: a new therapeutic paradigm for cancer--preclinical background: CTLA-4 and PD-1 blockade. Seminars in oncology 37: 430-439. 60. Keilholz, U. 2008. CTLA-4: negative regulator of the immune response and a target for cancer therapy. J Immunother 31: 431-439. 61. Verhagen, J., C. A. Sabatos, and D. C. Wraith. 2008. The role of CTLA-4 in immune regulation. Immunology letters 115: 73-74. 62. Lens, M., P. F. Ferrucci, and A. Testori. 2008. Anti-CTLA4 monoclonal antibody Ipilimumab in the treatment of metastatic melanoma: recent findings. Recent patents on anti-cancer drug discovery 3: 105-113. 63. Yang, J. C., M. Hughes, U. Kammula, R. Royal, R. M. Sherry, S. L. Topalian, K. B. Suri, C. Levy, T. Allen, S. Mavroukakis, I. Lowy, D. E. White, and S. A. Rosenberg. 2007. Ipilimumab (anti-CTLA4 antibody) causes regression of metastatic renal cell cancer associated with enteritis and hypophysitis. J Immunother 30: 825-830. 64. Ribas, A. 2007. Anti-CTLA4 Antibody Clinical Trials in Melanoma. Update on cancer therapeutics 2: 133-139. 65. Nishimura, H., M. Nose, H. Hiai, N. Minato, and T. Honjo. 1999. Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor. Immunity 11: 141-151. 66. Nishimura, H., T. Okazaki, Y. Tanaka, K. Nakatani, M. Hara, A. Matsumori, S. Sasayama, A. Mizoguchi, H. Hiai, N. Minato, and T. Honjo. 2001. Autoimmune dilated cardiomyopathy in PD-1 receptor-deficient mice. Science 291: 319-322. 67. Patsoukis, N., D. Sari, and V. A. Boussiotis. 2012. PD-1 inhibits T cell proliferation by upregulating p27 and p15 and suppressing Cdc25A. Cell Cycle 11: 4305-4309. 68. Merelli, B., D. Massi, L. Cattaneo, and M. Mandala. 2013. Targeting the PD1/PD-L1 axis in melanoma: Biological rationale, clinical challenges and opportunities. Critical reviews in oncology/hematology. 69. Kline, J., and T. F. Gajewski. 2010. Clinical development of mAbs to block the PD1 pathway as an immunotherapy for cancer. Curr Opin Investig Drugs 11: 1354-1359. 70. Tanaka, K., M. J. Albin, X. Yuan, K. Yamaura, A. Habicht, T. Murayama, M. Grimm, A. M. Waaga, T. Ueno, R. F. Padera, H. Yagita, M. Azuma, T. Shin, B. R. Blazar, D. M. Rothstein, M. H. Sayegh, and N. Najafian. 2007. PDL1 is required for peripheral transplantation tolerance and protection from chronic allograft rejection. J Immunol 179: 5204-5210. 71. Habicht, A., S. Dada, M. Jurewicz, B. T. Fife, H. Yagita, M. Azuma, M. H. Sayegh, and I. Guleria. 2007. A link between PDL1 and T regulatory cells in fetomaternal tolerance. J Immunol 179: 5211-5219. 72. Amarnath, S., C. W. Mangus, J. C. Wang, F. Wei, A. He, V. Kapoor, J. E. Foley, P. R. Massey, T. C. Felizardo, J. L. Riley, B. L. Levine, C. H. June, J. A. Medin, and D. H. Fowler. 2011. The PDL1-PD1 axis converts human TH1 cells into regulatory T cells. Science translational medicine 3: 111ra120. 73. Ding, H., X. Wu, and W. Gao. 2005. PD-L1 is expressed by human renal tubular epithelial cells and suppresses T cell cytokine synthesis. Clin Immunol 115: 184-191. 74. Abiko, K., M. Mandai, J. Hamanishi, Y. Yoshioka, N. Matsumura, T. Baba, K. Yamaguchi, R. Murakami, A. Yamamoto, B. Kharma, K. Kosaka, and I. Konishi. 2013. PD-L1 on tumor cells is induced in ascites and promotes peritoneal dissemination of ovarian cancer through CTL dysfunction. Clinical cancer research : an official journal of the American Association for Cancer Research 19: 1363-1374. 75. Kronenberg, M. 2005. Toward an understanding of NKT cell biology: progress and paradoxes. Annual review of immunology 23: 877-900. 76. Okajo, J., Y. Kaneko, Y. Murata, T. Tomizawa, C. Okuzawa, Y. Saito, T. Ishikawa-Sekigami, H. Okazawa, H. Ohnishi, T. Matozaki, and Y. Nojima. 2007. Regulation by Src homology 2 domain-containing protein tyrosine phosphatase substrate-1 of alpha-galactosylceramide-induced antimetastatic activity and Th1 and Th2 responses of NKT cells. J Immunol 178: 6164-6172. 77. Onoe, K., Y. Yanagawa, K. Minami, N. Iijima, and K. Iwabuchi. 2007. Th1 or Th2 balance regulated by interaction between dendritic cells and NKT cells. Immunologic research 38: 319-332. 78. Shin, T., T. Nakayama, Y. Akutsu, S. Motohashi, Y. Shibata, M. Harada, N. Kamada, C. Shimizu, E. Shimizu, T. Saito, T. Ochiai, and M. Taniguchi. 2001. Inhibition of tumor metastasis by adoptive transfer of IL-12-activated Valpha14 NKT cells. International journal of cancer. Journal international du cancer 91: 523-528. 79. Furlan, R., A. Bergami, D. Cantarella, E. Brambilla, M. Taniguchi, P. Dellabona, G. Casorati, and G. Martino. 2003. Activation of invariant NKT cells by alphaGalCer administration protects mice from MOG35-55-induced EAE: critical roles for administration route and IFN-gamma. European journal of immunology 33: 1830-1838. 80. Parekh, V. V., M. T. Wilson, D. Olivares-Villagomez, A. K. Singh, L. Wu, C. R. Wang, S. Joyce, and L. Van Kaer. 2005. Glycolipid antigen induces long-term natural killer T cell anergy in mice. The Journal of clinical investigation 115: 2572-2583. 81. Chang, Y. J., J. R. Huang, Y. C. Tsai, J. T. Hung, D. Wu, M. Fujio, C. H. Wong, and A. L. Yu. 2007. Potent immune-modulating and anticancer effects of NKT cell stimulatory glycolipids. Proceedings of the National Academy of Sciences of the United States of America 104: 10299-10304. 82. Wu, T. N., K. H. Lin, Y. J. Chang, J. R. Huang, J. Y. Cheng, A. L. Yu, and C. H. Wong. 2011. Avidity of CD1d-ligand-receptor ternary complex contributes to T-helper 1 (Th1) polarization and anticancer efficacy. Proceedings of the National Academy of Sciences of the United States of America 108: 17275-17280. 83. Lechler, R., J. G. Chai, F. Marelli-Berg, and G. Lombardi. 2001. The contributions of T-cell anergy to peripheral T-cell tolerance. Immunology 103: 262-269. 84. Zha, Y., R. Marks, A. W. Ho, A. C. Peterson, S. Janardhan, I. Brown, K. Praveen, S. Stang, J. C. Stone, and T. F. Gajewski. 2006. T cell anergy is reversed by active Ras and is regulated by diacylglycerol kinase-alpha. Nature immunology 7: 1166-1173. 85. Zheng, Y., Y. Zha, R. M. Spaapen, R. Mathew, K. Barr, A. Bendelac, and T. F. Gajewski. 2013. Egr2-dependent gene expression profiling and ChIP-Seq reveal novel biologic targets in T cell anergy. Molecular immunology 55: 283-291. 86. Ichikawa, D., M. Mizuno, T. Yamamura, and S. Miyake. 2011. GRAIL (gene related to anergy in lymphocytes) regulates cytoskeletal reorganization through ubiquitination and degradation of Arp2/3 subunit 5 and coronin 1A. The Journal of biological chemistry 286: 43465-43474. 87. Schartner, J. M., W. T. Simonson, S. A. Wernimont, L. M. Nettenstrom, A. Huttenlocher, and C. M. Seroogy. 2009. Gene related to anergy in lymphocytes (GRAIL) expression in CD4+ T cells impairs actin cytoskeletal organization during T cell/antigen-presenting cell interactions. The Journal of biological chemistry 284: 34674-34681. 88. Jeon, M. S., A. Atfield, K. Venuprasad, C. Krawczyk, R. Sarao, C. Elly, C. Yang, S. Arya, K. Bachmaier, L. Su, D. Bouchard, R. Jones, M. Gronski, P. Ohashi, T. Wada, D. Bloom, C. G. Fathman, Y. C. Liu, and J. M. Penninger. 2004. Essential role of the E3 ubiquitin ligase Cbl-b in T cell anergy induction. Immunity 21: 167-177. 89. Parekh, V. V., S. Lalani, S. Kim, R. Halder, M. Azuma, H. Yagita, V. Kumar, L. Wu, and L. V. Kaer. 2009. PD-1/PD-L blockade prevents anergy induction and enhances the anti-tumor activities of glycolipid-activated invariant NKT cells. J Immunol 182: 2816-2826. 90. Tsushima, F., S. Yao, T. Shin, A. Flies, S. Flies, H. Xu, K. Tamada, D. M. Pardoll, and L. Chen. 2007. Interaction between B7-H1 and PD-1 determines initiation and reversal of T-cell anergy. Blood 110: 180-185. 91. Kojo, S., C. Elly, Y. Harada, W. Y. Langdon, M. Kronenberg, and Y. C. Liu. 2009. Mechanisms of NKT cell anergy induction involve Cbl-b-promoted monoubiquitination of CARMA1. Proceedings of the National Academy of Sciences of the United States of America 106: 17847-17851. 92. Simpson, K. D., and J. V. Cross. 2013. MIF: metastasis/MDSC-inducing factor? Oncoimmunology 2: e23337. 93. Bunt, S. K., P. Sinha, V. K. Clements, J. Leips, and S. Ostrand-Rosenberg. 2006. Inflammation induces myeloid-derived suppressor cells that facilitate tumor progression. J Immunol 176: 284-290. 94. Sinha, P., V. K. Clements, and S. Ostrand-Rosenberg. 2005. Reduction of myeloid-derived suppressor cells and induction of M1 macrophages facilitate the rejection of established metastatic disease. J Immunol 174: 636-645. 95. Youn, J. I., S. Nagaraj, M. Collazo, and D. I. Gabrilovich. 2008. Subsets of myeloid-derived suppressor cells in tumor-bearing mice. J Immunol 181: 5791-5802. 96. Dugast, A. S., T. Haudebourg, F. Coulon, M. Heslan, F. Haspot, N. Poirier, R. Vuillefroy de Silly, C. Usal, H. Smit, B. Martinet, P. Thebault, K. Renaudin, and B. Vanhove. 2008. Myeloid-derived suppressor cells accumulate in kidney allograft tolerance and specifically suppress effector T cell expansion. J Immunol 180: 7898-7906. 97. Hanson, E. M., V. K. Clements, P. Sinha, D. Ilkovitch, and S. Ostrand-Rosenberg. 2009. Myeloid-derived suppressor cells down-regulate L-selectin expression on CD4+ and CD8+ T cells. J Immunol 183: 937-944. 98. Moline-Velazquez, V., H. Cuervo, V. Vila-Del Sol, M. C. Ortega, D. Clemente, and F. de Castro. 2011. Myeloid-derived suppressor cells limit the inflammation by promoting T lymphocyte apoptosis in the spinal cord of a murine model of multiple sclerosis. Brain Pathol 21: 678-691. 99. Li, H., Y. Han, Q. Guo, M. Zhang, and X. Cao. 2009. Cancer-expanded myeloid-derived suppressor cells induce anergy of NK cells through membrane-bound TGF-beta 1. J Immunol 182: 240-249. 100. Rodriguez, P. C., and A. C. Ochoa. 2008. Arginine regulation by myeloid derived suppressor cells and tolerance in cancer: mechanisms and therapeutic perspectives. Immunological reviews 222: 180-191. 101. Raber, P., A. C. Ochoa, and P. C. Rodriguez. 2012. Metabolism of L-arginine by myeloid-derived suppressor cells in cancer: mechanisms of T cell suppression and therapeutic perspectives. Immunological investigations 41: 614-634. 102. Morales, J. K., M. Kmieciak, K. L. Knutson, H. D. Bear, and M. H. Manjili. 2010. GM-CSF is one of the main breast tumor-derived soluble factors involved in the differentiation of CD11b-Gr1- bone marrow progenitor cells into myeloid-derived suppressor cells. Breast cancer research and treatment 123: 39-49. 103. Dominguez-Soto, A., E. Sierra-Filardi, A. Puig-Kroger, B. Perez-Maceda, F. Gomez-Aguado, M. T. Corcuera, P. Sanchez-Mateos, and A. L. Corbi. 2011. Dendritic cell-specific ICAM-3-grabbing nonintegrin expression on M2-polarized and tumor-associated macrophages is macrophage-CSF dependent and enhanced by tumor-derived IL-6 and IL-10. J Immunol 186: 2192-2200. 104. Sinha, P., V. K. Clements, and S. Ostrand-Rosenberg. 2005. Interleukin-13-regulated M2 macrophages in combination with myeloid suppressor cells block immune surveillance against metastasis. Cancer research 65: 11743-11751. 105. Bansal, V., and J. B. Ochoa. 2003. Arginine availability, arginase, and the immune response. Current opinion in clinical nutrition and metabolic care 6: 223-228. 106. Kroeger, K. M., B. M. Sullivan, and R. M. Locksley. 2009. IL-18 and IL-33 elicit Th2 cytokines from basophils via a MyD88- and p38alpha-dependent pathway. Journal of leukocyte biology 86: 769-778. 107. Bourgeois, E., L. P. Van, M. Samson, S. Diem, A. Barra, S. Roga, J. M. Gombert, E. Schneider, M. Dy, P. Gourdy, J. P. Girard, and A. Herbelin. 2009. The pro-Th2 cytokine IL-33 directly interacts with invariant NKT and NK cells to induce IFN-gamma production. European journal of immunology 39: 1046-1055. 108. Ali, S., M. Huber, C. Kollewe, S. C. Bischoff, W. Falk, and M. U. Martin. 2007. IL-1 receptor accessory protein is essential for IL-33-induced activation of T lymphocytes and mast cells. Proceedings of the National Academy of Sciences of the United States of America 104: 18660-18665. 109. Ho, L. H., T. Ohno, K. Oboki, N. Kajiwara, H. Suto, M. Iikura, Y. Okayama, S. Akira, H. Saito, S. J. Galli, and S. Nakae. 2007. IL-33 induces IL-13 production by mouse mast cells independently of IgE-FcepsilonRI signals. Journal of leukocyte biology 82: 1481-1490. 110. Ali, S., A. Mohs, M. Thomas, J. Klare, R. Ross, M. L. Schmitz, and M. U. Martin. 2011. The dual function cytokine IL-33 interacts with the transcription factor NF-kappaB to dampen NF-kappaB-stimulated gene transcription. J Immunol 187: 1609-1616. 111. Funakoshi-Tago, M., K. Tago, Y. Sato, S. Tominaga, and T. Kasahara. 2011. JAK2 is an important signal transducer in IL-33-induced NF-kappaB activation. Cellular signalling 23: 363-370. 112. Pastorelli, L., C. De Salvo, M. Vecchi, and T. T. Pizarro. 2013. The role of IL-33 in gut mucosal inflammation. Mediators of inflammation 2013: 608187. 113. Lopetuso, L. R., F. Scaldaferri, and T. T. Pizarro. 2012. Emerging role of the interleukin (IL)-33/ST2 axis in gut mucosal wound healing and fibrosis. Fibrogenesis &; tissue repair 5: 18. 114. Hu, L. A., Y. Fu, D. N. Zhang, and J. Zhang. 2013. Serum IL-33 as a diagnostic and prognostic marker in non- small cell lung cancer. Asian Pacific journal of cancer prevention : APJCP 14: 2563-2566. 115. Bergis, D., V. Kassis, A. Ranglack, V. Koeberle, A. Piiper, B. Kronenberger, S. Zeuzem, O. Waidmann, and H. H. Radeke. 2013. High Serum Levels of the Interleukin-33 Receptor Soluble ST2 as a Negative Prognostic Factor in Hepatocellular Carcinoma. Translational oncology 6: 311-318. 116. Jovanovic, I. P., N. N. Pejnovic, G. D. Radosavljevic, J. M. Pantic, M. Z. Milovanovic, N. N. Arsenijevic, and M. L. Lukic. 2013. Interleukin-33/ST2 axis promotes breast cancer growth and metastases by facilitating intratumoral accumulation of immunosuppressive and innate lymphoid cells. International journal of cancer. Journal international du cancer. 117. Masamune, A., T. Watanabe, K. Kikuta, K. Satoh, A. Kanno, and T. Shimosegawa. 2010. Nuclear expression of interleukin-33 in pancreatic stellate cells. American journal of physiology. Gastrointestinal and liver physiology 299: G821-832. 118. Fujii, H., S. Seki, S. Kobayashi, T. Kitada, N. Kawakita, K. Adachi, H. Tsutsui, K. Nakanishi, H. Fujiwara, Y. Ikarashi, M. Taniguchi, M. Kronenberg, M. Ikemoto, Y. Nakajima, T. Arakawa, and K. Kaneda. 2005. A murine model of NKT cell-mediated liver injury induced by alpha-galactosylceramide/d-galactosamine. Virchows Archiv : an international journal of pathology 446: 663-673. 119. Liu, W., Y. Hou, H. Chen, H. Wei, W. Lin, J. Li, M. Zhang, F. He, and Y. Jiang. 2011. Sample preparation method for isolation of single-cell types from mouse liver for proteomic studies. Proteomics 11: 3556-3564. 120. Zheng, Y., Y. Zha, and T. F. Gajewski. 2008. Molecular regulation of T-cell anergy. EMBO reports 9: 50-55. 121. Fujio, M., D. Wu, R. Garcia-Navarro, D. D. Ho, M. Tsuji, and C. H. Wong. 2006. Structure-based discovery of glycolipids for CD1d-mediated NKT cell activation: tuning the adjuvant versus immunosuppression activity. Journal of the American Chemical Society 128: 9022-9023. 122. Sidobre, S., O. V. Naidenko, B. C. Sim, N. R. Gascoigne, K. C. Garcia, and M. Kronenberg. 2002. The V alpha 14 NKT cell TCR exhibits high-affinity binding to a glycolipid/CD1d complex. J Immunol 169: 1340-1348. 123. Liu, Y., Y. Yu, S. Yang, B. Zeng, Z. Zhang, G. Jiao, Y. Zhang, L. Cai, and R. Yang. 2009. Regulation of arginase I activity and expression by both PD-1 and CTLA-4 on the myeloid-derived suppressor cells. Cancer immunology, immunotherapy : CII 58: 687-697. 124. Arshad, M. I., M. Rauch, A. L'Helgoualc'h, V. Julia, M. C. Leite-de-Moraes, C. Lucas-Clerc, C. Piquet-Pellorce, and M. Samson. 2011. NKT cells are required to induce high IL-33 expression in hepatocytes during ConA-induced acute hepatitis. European journal of immunology 41: 2341-2348. 125. Nakagawa, R., I. Nagafune, Y. Tazunoki, H. Ehara, H. Tomura, R. Iijima, K. Motoki, M. Kamishohara, and S. Seki. 2001. Mechanisms of the antimetastatic effect in the liver and of the hepatocyte injury induced by alpha-galactosylceramide in mice. J Immunol 166: 6578-6584. 126. Arshad, M. I., C. Piquet-Pellorce, A. L'Helgoualc'h, M. Rauch, S. Patrat-Delon, F. Ezan, C. Lucas-Clerc, S. Nabti, A. Lehuen, F. J. Cubero, J. P. Girard, C. Trautwein, and M. Samson. 2012. TRAIL but not FasL and TNFalpha, regulates IL-33 expression in murine hepatocytes during acute hepatitis. Hepatology 56: 2353-2362. 127. Mittelstadt, P. R., and J. D. Ashwell. 1999. Role of Egr-2 in up-regulation of Fas ligand in normal T cells and aberrant double-negative lpr and gld T cells. The Journal of biological chemistry 274: 3222-3227. 128. Bonello, M. R., and L. M. Khachigian. 2004. Fibroblast growth factor-2 represses platelet-derived growth factor receptor-alpha (PDGFR-alpha) transcription via ERK1/2-dependent Sp1 phosphorylation and an atypical cis-acting element in the proximal PDGFR-alpha promoter. The Journal of biological chemistry 279: 2377-2382. 129. Ostrand-Rosenberg, S. 2010. Myeloid-derived suppressor cells: more mechanisms for inhibiting antitumor immunity. Cancer immunology, immunotherapy : CII 59: 1593-1600. 130. Sintes, J., M. Cuenca, X. Romero, R. Bastos, C. Terhorst, A. Angulo, and P. Engel. 2013. Cutting edge: Ly9 (CD229), a SLAM family receptor, negatively regulates the development of thymic innate memory-like CD8+ T and invariant NKT cells. J Immunol 190: 21-26. 131. D'Andrea, A., D. Goux, C. De Lalla, Y. Koezuka, D. Montagna, A. Moretta, P. Dellabona, G. Casorati, and S. Abrignani. 2000. Neonatal invariant Valpha24+ NKT lymphocytes are activated memory cells. European journal of immunology 30: 1544-1550. 132. Valentine, M., K. Song, G. A. Maresh, H. Mack, M. C. Huaman, P. Polacino, O. Ho, A. Cristillo, H. Kyung Chung, S. L. Hu, and S. H. Pincus. 2013. Expression of the memory marker CD45RO on helper T cells in macaques. PloS one 8: e73969. 133. Jackson, S. S., J. E. Schmitz, M. J. Kuroda, P. F. McKay, S. M. Sumida, K. L. Martin, F. Yu, M. A. Lifton, D. A. Gorgone, and N. L. Letvin. 2005. Evaluation of CD62L expression as a marker for vaccine-elicited memory cytotoxic T lymphocytes. Immunology 116: 443-453. 134. Varga, S. M., and R. M. Welsh. 1996. The CD45RB-associated epitope defined by monoclonal antibody CZ-1 is an activation and memory marker for mouse CD4 T cells. Cellular immunology 167: 56-62. 135. Mirshahidi, S., C. T. Huang, and S. Sadegh-Nasseri. 2001. Anergy in peripheral memory CD4(+) T cells induced by low avidity engagement of T cell receptor. The Journal of experimental medicine 194: 719-731. 136. Li, S., T. Miao, M. Sebastian, P. Bhullar, E. Ghaffari, M. Liu, A. L. Symonds, and P. Wang. 2012. The transcription factors Egr2 and Egr3 are essential for the control of inflammation and antigen-induced proliferation of B and T cells. Immunity 37: 685-696. 137. Song, L., S. Asgharzadeh, J. Salo, K. Engell, H. W. Wu, R. Sposto, T. Ara, A. M. Silverman, Y. A. DeClerck, R. C. Seeger, and L. S. Metelitsa. 2009. Valpha24-invariant NKT cells mediate antitumor activity via killing of tumor-associated macrophages. The Journal of clinical investigation 119: 1524-1536. 138. Turnquist, H. R., Z. Zhao, B. R. Rosborough, Q. Liu, A. Castellaneta, K. Isse, Z. Wang, M. Lang, D. B. Stolz, X. X. Zheng, A. J. Demetris, F. Y. Liew, K. J. Wood, and A. W. Thomson. 2011. IL-33 expands suppressive CD11b+ Gr-1(int) and regulatory T cells, including ST2L+ Foxp3+ cells, and mediates regulatory T cell-dependent promotion of cardiac allograft survival. J Immunol 187: 4598-4610. 139. Peranzoni, E., S. Zilio, I. Marigo, L. Dolcetti, P. Zanovello, S. Mandruzzato, and V. Bronte. 2010. Myeloid-derived suppressor cell heterogeneity and subset definition. Current opinion in immunology 22: 238-244. 140. Osman, Y., T. Kawamura, T. Naito, K. Takeda, L. Van Kaer, K. Okumura, and T. Abo. 2000. Activation of hepatic NKT cells and subsequent liver injury following administration of alpha-galactosylceramide. European journal of immunology 30: 1919-1928. 141. Rengarajan, J., P. R. Mittelstadt, H. W. Mages, A. J. Gerth, R. A. Kroczek, J. D. Ashwell, and L. H. Glimcher. 2000. Sequential involvement of NFAT and Egr transcription factors in FasL regulation. Immunity 12: 293-300. 142. Liew, F. Y., N. I. Pitman, and I. B. McInnes. 2010. Disease-associated functions of IL-33: the new kid in the IL-1 family. Nature reviews. Immunology 10: 103-110. 143. Arshad, M. I., C. Piquet-Pellorce, and M. Samson. 2012. IL-33 and HMGB1 alarmins: sensors of cellular death and their involvement in liver pathology. Liver international : official journal of the International Association for the Study of the Liver 32: 1200-1210. 144. Barbalat, R., S. E. Ewald, M. L. Mouchess, and G. M. Barton. 2011. Nucleic acid recognition by the innate immune system. Annual review of immunology 29: 185-214. 145. Ugel, S., F. Delpozzo, G. Desantis, F. Papalini, F. Simonato, N. Sonda, S. Zilio, and V. Bronte. 2009. Therapeutic targeting of myeloid-derived suppressor cells. Current opinion in pharmacology 9: 470-481.
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