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研究生:邱華晧
研究生(外文):Hua Hao Chiu
論文名稱:紫背萬年青之化學成分與生物活性研究
論文名稱(外文):Chemical and Biological Investigations of Rhoeo spathacea (Sw.) Stearn
指導教授:呂彥禮
指導教授(外文):Y. L. Leu
學位類別:碩士
校院名稱:長庚大學
系所名稱:中醫學系天然藥物
學門:醫藥衛生學門
學類:藥學學類
論文種類:學術論文
論文出版年:2015
畢業學年度:103
論文頁數:125
中文關鍵詞:紫背萬年青胰島素阻抗PEPCK mRNAG6Pase mRNA
外文關鍵詞:Rhoeo spathaceainsulin resistancePEPCK mRNAG6Pase mRNA
相關次數:
  • 被引用被引用:0
  • 點閱點閱:193
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指導教授推薦書...................................................................
口試委員審定書...................................................................
致謝.........................................................................iii
中文摘要......................................................................iv
Abstract......................................................................v
目錄..........................................................................vi
第一章 緒論.....................................................................1
1.1 緒言.......................................................................1
1.2 紫背萬年青的植物形態與分佈...................................................4
1.3 研究動機...................................................................7
第二章 文獻回顧.................................................................8
2.1 紫背萬年青屬(Rhoeo)植物之化學成分回顧.........................................8
2.2 紫背萬年青屬(Rhoeo)植物之藥理研究及活性回顧....................................20
第三章 抽取與分離...............................................................33
第四章 化合物之結構解析..........................................................43
4.1 Bracteanolide A (1)結構解析................................................43
4.2 Bracteanolide B (2)結構解析................................................48
4.3 (R)-2-Hydroxy-3-(4'-hydroxyphenyl)propanoic acid (3)結構解析...............53
4.4 Phytol (18)結構解析........................................................57
4.5 Isophytol (19)結構解析.....................................................61
4.6 2,3-Dihydroxy-2-methyl-butyrolactone (22)結構解析..........................65
4.7 其它化合物之結構............................................................70
第五章 生物試驗.................................................................71
第六章 實驗部分.................................................................74
6.1 實驗儀器與藥品..............................................................74
6.2 紫背萬年青分離與純化.........................................................76
6.3 生物活性試驗之方法...........................................................80
第七章 結果與討論................................................................84
光譜數據........................................................................88
參考文獻.......................................................................109



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