(3.237.97.64) 您好!臺灣時間:2021/03/03 01:46
字體大小: 字級放大   字級縮小   預設字形  
回查詢結果

詳目顯示:::

我願授權國圖
: 
twitterline
研究生:蘇清菁
研究生(外文):Ching-Ching Su
論文名稱:癌症存活者身體活動、生物節律與生活品質之關係:老年與年輕者之比較
論文名稱(外文):The relationship of physical activity, circadian rhythm and quality of life: A comparison between younger and older cancer survivors
指導教授:林佳靜林佳靜引用關係
指導教授(外文):Chia-Chin Lin
口試委員:張俊彥林寬佳張秀如鄭綺
口試委員(外文):Jang-Yang ChangKuan-Chia LinHsiu-Ju ChangJeng C
口試日期:2015-12-28
學位類別:博士
校院名稱:臺北醫學大學
系所名稱:護理學研究所
學門:醫藥衛生學門
學類:護理學類
論文種類:學術論文
論文出版年:2016
畢業學年度:104
語文別:中文
論文頁數:150
中文關鍵詞:年齡癌症存活者身體活動生物節律生活品質
外文關鍵詞:Agecancer survivorsphysical activitycircadian rhythmquality of life
相關次數:
  • 被引用被引用:0
  • 點閱點閱:56
  • 評分評分:系統版面圖檔系統版面圖檔系統版面圖檔系統版面圖檔系統版面圖檔
  • 下載下載:0
  • 收藏至我的研究室書目清單書目收藏:0
本研究為探討老年與年輕癌症存活者身體活動、生物節律與生活品質之關係的系列研究,包含二個子研究。
子研究一:台灣版老人身體活動量表於癌症存活者之發展與測試
研究背景:問卷是一種容易實施且經濟實惠的身體活動評估方法,但是僅有少數研究曾驗證身體活動問卷在癌症存活者的信效度。老人身體活動量表被廣泛使用於需要較緩和性身體活動的族群,但在癌症存活者的信效度尚未被驗證。
研究方法:利用雙向翻譯完成台灣版老人身體活動量表(Taiwanese version of the Physical Activity Scale for the Elderly, PASE-T)基本架構,於血液腫瘤科門診共收集127位癌症存活者資料,研究工具包含:台灣版安德森症狀量表(Taiwanese version of the MD Anderson Symptom Inventory, MDASI-T)、Karnofsky功能評估量表(Karnofsky Performonce Status, KPS)及活動記錄器等。
研究結果:內容效度為0.91,與actigraph平均每分鐘測量次數之斯皮爾曼等級相關係數為0.64,其效標關聯效度良好。與KPS、MDASI-T量表之症狀嚴重度與症狀干擾之斯皮爾曼等級相關係數為0.59, −0.23, −0.21,具備可接受的聚斂效度。此外,此量表能區分出身體功能好與差者的身體活動量。整體量表與次量表之再測信度為0.90, 0.78, 0.83, 0.97。
研究結論:台灣版老人身體活動量表具有良好的信度及效度。

子研究二:老年與年輕癌症存活者身體活動、生物節律與生活品質之關係:生物節律中介角色與劑量反應關係之探討
研究背景:愈來愈多的實證研究顯示身體活動可以促進癌症存活者的生活品質,但是尚不了解身體活動與生活品質之間潛在的生物關係,亦缺乏身體活動、生物節律與生活品質劑量反應關係之實證研究,此劑量反應關係是否存在年齡差異亦不清楚。
研究方法:採用橫斷式研究設計,共收集143位年輕及92位老年癌症存活者資料。研究工具包含:KPS、PASE-T、台灣版SF-36健康評估量表及活動記錄器等,以多種中介分析方法測試中介反應,並利用多變量變異數分析探討身體活動與生物節律及生活品質的劑量反應關係。
研究結果:不論是老年或年輕族群,生物節律都是身體活動與生理層面生活品質的中介因子,生物節律在老年族群的中介反應大於年輕族群。於心理層面的生活品質,在年輕族群,未發現生物節律的中介效果,但在老年族群,生物節律具有部分中介效果。於兩個族群,身體活動與生物節律及生活品質均具有線性的劑量反應關係,達到癌症存活者身體活動量建議者,都有較佳的生物節律及生理層面生活品質,一週總身體活動持續時間,年輕者達到19小時以上,老年者達到12小時以上,能有較佳的生物節律及生活品質。
研究結論:身體活動與生活品質之間的關係具有年齡差異性,而身體活動與生物節律及生活品質具有劑量反應關係,但無年齡差異。
總結,本系列研究結果有助於瞭解不同年齡層癌症存活者身體活動與生活品質之間潛在的生物關係,以及其差異性。此外,也提出不同年齡層癌症存活者身體活動、生物節律與生活品質劑量反應關係之實證證明,以作為未來年輕及老年癌症存活者身體活動介入的參考。
Project 1: Measurement of Physical Activity in Cancer Survivors: A Validity Study
Background: Few studies have verified the reliability and validity of the various physical activity questionnaires in cancer patients.
Objective: To validate the Taiwanese version of the Physical Activity Scale for the Elderly (PASE-T).
Methods: One hundred twenty-seven cancer survivors participated in this study. Instruments consisted of the PASE-T, the Taiwanese version of the MD Anderson Symptom Inventory (MDASI-T), Karnofsky Performance Status (KPS), and actigraph. Reliability was assessed by calculating the test-retest reliability. The validity was assessed by the content validity, criterion-related validity, convergent validity, and known group validity.
Results: The test-retest reliability was 0.90 over a 2-week interval, based on a sample of 30 patients. The content validity index was very acceptable at 0.91. Convergent validity was demonstrated by its significant association with MADSI-T scores (symptom severity: r = -0.23, p = 0.001; symptom interference: r = -0.21, p = 0.001) and KPS scores (r = 0.59, p < 0.001). Criterion-related validity was established by a significant relationship to the actigraph total counts per minute (r = 0.64, p < 0.001). Known group validity was established by its ability to detect significant differences according to a patient’s performance status.
Conclusion: The PASE-T is a reliable and valid instrument for measurement of physical activity among cancer survivors in Taiwan.

Project 2: The relationship of physical activity, circadian rhythm and quality of life in younger and older cancer survivors
Background: Increasing evidence suggests that physical activity (PA) improves the quality of life (QoL) of cancer survivors. However, the biological associations underlying the relationship between PA and QoL are unclear. There is lack of dose-response information about PA, CR and QoL in cancer survivors and it is unclear whether young and old cancer survivor differs in the relationship between PA, CR, and QoL.
Objective: 1.To determine whether the relationship between PA and QoL differs in younger and older cancer survivors and whether circadian rhythm (CR) mediates this relationship. 2. To explore the dose-response relationship between physical activity, CR and QoL in young and old cancer survivors.
Methods: The participants were 235 cancer survivors, comprising 143 younger and 92 older patients. Data were collected using the PASE-T and Short Form-36. The robustness and stability of the CR were measured using an actigraph. Mediation was tested using multiple mediation analyses. Multivariate analysis of variance was used to determine the dose-response relationships between PA to CR and QoL.
Results: The CR mediated the relationship between PA and the physical domain of QoL in younger and older cancer survivors (23% and 59% mediating effects, respectively). The CR partially mediated the effect of PA on the mental dimension of QoL in older cancer survivors (36% mediating effect), but not in younger cancer survivors. There was a liner dose-response relationship between PA, CR, and QoL in each age group. Meeting the PA recommendations was with higher CR and physical domain of QoL. Cancer survivors who reported total PA more than 19 hours of young and 12 hours of old over the past week had a better QoL and CR.
Conclusion: The mediating effect differed in younger and older cancer survivors. The dose-response relationship of PA on CR and QoL appeared the same in young and old cancer survivors.
In conclusion, the results of the series studies help to understand the the biological mechanisms underlying the relationship between PA and QoL among cancer survivors with different age groups. In addition, the results also provide evidence that the dose-response relationship of PA to CR and QoL among different age groups. These results can serve as a reference in designing individualized PA programs for cancer survivors.
目 錄
頁 數
致 謝 .................................................Ⅰ
中文摘要 .................................................Ⅲ
英文摘要 .................................................Ⅵ
目 錄 .................................................Ⅸ
圖表目次 .................................................XII
第一章 緒論
第一節 研究動機與重要性 .................................1
第二節 研究目的 .........................................4
第三節 研究問題 .........................................5
第二章 文獻查證
第一節 身體活動相關之概念 .........................7
第二節 生物節律相關之概念 .........................19
第三節 癌症患者生活品質相關之概念 .................22
第四節 癌症患者身體活動、生物節律與生活品質相關之
研究...........................................25
第三章 研究方法
第一節 研究概念架構........................................................28
第二節 子研究一:台灣版老人身體活動量表於癌症存活
者之發展與測試.....................................29
第三節 子研究二:老年與年輕癌症存活者身體活動、生
物節律與生活品質之關係:生物節律中介角色
與劑量反應關係之探討.............................40
第四章 研究結果
第一節 子研究一:台灣版老人身體活動量表於癌症存活
者之發展與測試......................................51
第二節 子研究二:老年與年輕癌症存活者身體活動、生
物節律與生活品質之關係:生物節律中介角色與
劑量反應關係之探討...............................54
第五章 討論
第一節 子研究一:台灣版老人身體活動量表於癌症存活
者之發展與測試......................................60
第二節 子研究二:老年與年輕癌症存活者身體活動、生
物節律與生活品質之關係:生物節律中介角色與
劑量反應關係之探討..................... .........64
第六章 結論與建議
第一節 結論.............................................72
第二節 研究限制.........................................73
第三節 應用與建議.......................................75
參考資料
中文部份...................................................77
英文部份...................................................77

附錄
附錄一 專家效度名單.........................................117
附錄二 專家效度修正結果.........................................................118
附錄三 老人身體活動量表(PASE)計分方式.....................120
附錄四 人體試驗倫理委員會同意臨床試驗證明書..................122
附錄五 研究問卷............................................123

表目次 頁 數
表一、癌症患者身體活動量建議.......................................................98
表二、研究對象基本資料及疾病治療特性.......................100
表三、台灣版老人身體活動量表分數在不同年齡及性別之比較.......................................................101
表四、台灣版老人身體活動量表與Karnofsky功能評估量表、台灣版安德森症狀量表及活動記錄器之關係..................................102
表五、高身體功能與低身體功能者老人身體活動量表分數之比較........................................................103

表六、身體活動量之預測因子..................................104
表七、個案基本資料與臨床特性................................105
表八、不同年齡層身體活動、生物節律及生活品質之相關性 ..........106
表九、不同年齡層生物節律於身體活動及生活品質之中介分析........................................................107
表十、好與壞生物節律病人生活品質之比較.......................110
表十一、年輕及老年癌症存活者身體活動、生物節律及生活品質之比較........................................................111
表十二、年輕及老年癌症存活者身體活動、生物節律及生活品質之劑量反應關係......................................................112
表十三、年輕及老年癌症存活者符合及未符合身體活動建議者生物節律及生活品質之差異.............................................. 115
表十四、每週總身體活動持續時間超過及不足中位數者生物節律與生活品質之差異....................................................116

圖目次 頁 數
圖一、研究概念架構圖.......................................28
圖二、資料蒐集過程示意圖........................................................39
圖三、中介變項路徑分析圖........................................................48
圖四、生物節律(I < O)在身體活動與生理層面生活品質的中介路徑........................................................108
圖五、生物節律(I < O)在身體活動與心理層面生活品質的中介路徑........................................................109
圖六、年輕及老年癌症存活者於不同身體活動程度,(a)生理層面生活品質、(b)心理層面生活品質、(c)生物節律: I < O、(d)生物節律: r24的平均值及標準差之比較........................................................113
參考文獻
呂昌明、林旭龍、黃奕清、李明憲、王淑芳(2000)・身體活動自我報告量表之效度及信度的研究—以TriTrac-R3D三度空間加速器為效標・衛生教育學報,15,99-114。
林佳慧、丘周萍(2002)・運動之概念分析・護理雜誌,49(6),83-88。
吳佳儀(2002)・社區老人睡眠品質與身體活動、憂鬱之相關性探討・未出版碩士論文,國立臺灣大學,臺北市。
李亞珊、朱真儀、林貴福(2010)・台灣地區身體活動量表之應用研究・運動生理暨體能學報,11,1-12。
衛生福利部國民健康署(2014)・國人身體活動建議量・取自http://health99.hpa.gov.tw/Article/ArticleDetail.aspx?TopIcNo=827&DS=1-life
Aaronson, N. K., Ahmedzai, S., Bergman, B., Bullinger, M., Cull, A., Duez, N. J., ... & Takeda, F. (1993). The European Organization for Research and Treatment of Cancer QLQ-C30: A quality-of-life instrument for use in international clinical trials in oncology. Journal of the National Cancer Institute, 85(5), 365-376.
Abbey, A., & Andrews, F. M. (1984). Modeling the psychological determinants of life quality. Social Indicators Research, 16(1), 1-34.
Alfano, C. M., Smith, A. W., Irwin, M. L., Bowen, D. J., Sorensen, B., Reeve, B. B., ... & McTiernan, A. (2007). Physical activity, long-term symptoms, and physical health-related quality of life among breast cancer survivors: A prospective analysis. Journal of Cancer Survivorship, 1(2), 116-128.
Baron, R. M., & Kenny, D. A. (1986). The moderator–mediator variable distinction in social psychological research: Conceptual, strategic, and statistical considerations. Journal of Personality and Social Psychology, 51(6), 1173-1182.
Bauman, A., Ma, G., Cuevas, F., Omar, Z., Waqanivalu, T., Phongsavan, P., ... & Bhushan, A. (2011). Cross-national comparisons of socioeconomic differences in the prevalence of leisure-time and occupational physical activity, and active commuting in six Asia-Pacific countries. Journal of Epidemiology and Community Health, 65(1), 35-43.
Belanger, L. J., Plotnikoff, R. C., Clark, A., & Courneya, K. S. (2011). Physical activity and health-related quality of life in young adult cancer survivors: A Canadian provincial survey. Journal of Cancer Survivorship, 5(1), 44-53.
Berger, A. M., Hertzog, M., Geary, C. R., Fischer, P., & Farr, L. (2012). Circadian rhythms, symptoms, physical functioning, and body mass index in breast cancer survivors. Journal of Cancer Survivorship, 6(3), 305-314.
Bial, A. K., Schilsky, R. L., & Sachs, G. A. (2006). Evaluation of cognition in cancer patients: Special focus on the elderly. Critical Reviews in Oncology/Hematology, 60, 242-255.
Bize, R., Johnson, J. A., & Plotnikoff, R. C. (2007). Physical activity level and health-related quality of life in the general adult population: A systematic review. Preventive Medicine, 45(6), 401-415.
Blaney, J. M., Lowe-Strong, A., Rankin-Watt, J., Campbell, A., & Gracey, J. H. (2013). Cancer survivors'' exercise barriers, facilitators and preferences in the context of fatigue, quality of life and physical activity participation: A questionnaire-survey. Psycho-Oncology, 22(1), 186-194.
Bloom, J. R., Petersen, D. M., & Kang, S. H. (2007). Multi‐dimensional quality of life among long‐term (5+ years) adult cancer survivors. Psycho‐Oncology, 16(8), 691-706.
Bouchard, C., Tremblay, A., LeBlang, C., Lortie, G., Sauard, R., & Therialt, G. A. (1983). Methods to assess energy expenditure in children and adults. American Journal of Clinical Nutrition, 37, 461-467.
Brawley, L. R., Rejeski, W. J., & King, A. C. (2003). Promoting physical activity for older adults: The challenges for changing behavior. American Journal of Preventive Medicine, 25(3), 172-183.
Buffart, L. M., Thong, M. S., Schep, G., Chinapaw, M. J., Brug, J., & Van De Poll-franse, L. V. (2012). Self-reported physical activity: Its correlates and relationship with health-related quality of life in a large cohort of colorectal cancer survivors. PloS One, 7(5), e36164.
Campbell, K. L., Crocker, P. R. E. & McKenzie, D. C.(2002). Field evaluation of energy expenditure in women using Tritrac accelerometers. Medicine and Science in Sports and Exercise, 34, 1667-1674.
Caspersen, C. J., Powell, K. E., & Christenson, G. M. (1985). Physical activity, exercise, and physical fitness: Definitions and distinctions for health-realated research. Public Health Reports, 100, 126-131.
Cella, D. F., Tulsky, D. S., Gray, G., Sarafian, B., Linn, E., Bonomi, A., ... & Brannon, J. (1993). The Functional Assessment of Cancer Therapy scale: Development and validation of the general measure. Journal of Clinical Oncology, 11(3), 570-579.
Champion, V. L., Wagner, L. I., Monahan, P. O., Daggy, J., Smith, L., Cohee, A., ... & Sledge, G. W. (2014). Comparison of younger and older breast cancer survivors and age‐matched controls on specific and overall quality of life domains. Cancer, 120(15), 2237-2246.
Chen, P. Y., & Chang, H. C. (2012). The coping process of patients with cancer. European Journal of Oncology Nursing, 16(1), 10-16.
Chen, K. K. F., & Lee, D. T. F. (2011). Effects of pain, fatigue, insomnia, and mood disturbance on functionalstatus and quality of life of elderly patients with cancer. Critical Reviews in Oncology Hematology, 78(2), 127-137.
Chie, W. C., Huang, C. S., Chen, J. H., & Chang, K. J. (1999). Measurement of the quality of life during different clinical phases of breast cancer. Journal Formos Medicine Association, 98, 254-260.
Chou, P. L., Rau, K. M., & Lin, C. C. (2011). Development and psychometric testing of a short version of the Barriers Questionnaire-Taiwan form for cancer patients. International journal of nursing studies, 48(9), 1071-1079.
Chu, E. Y. W., McManus, A. M. & Yu, C.C.W.(2007). Calibration of the RT3 accelerometer for ambulation and nonambulation in children. Medicine and Science in Sports and Exercise, 39, 2085-2091.
Cleeland, C. S., Mendoza, T. R., Wang, X. S., Chou, C., Harle, M. T., Morrissey, M., & Engstrom, M. C. (2000). Assessing symptom distress in cancer patients: The M. D. Anderson Symptom Inventory. Cancer, 89, 1634-1646.
Costa, I. C., Carvalho, H. N., & Fernandes, L. (2013). Aging, circadian rhythms and depressive disorders: A review. American Journal of Neurodegenerative Disease, 2, 228-246.
Coups, E. J., Park, B. J., Feinstein, M. B., Steingart, R. M., Egleston, B. L., Wilson, D. J., & Ostroff, J. S. (2009). Physical activity among lung cancer survivors: Changes across the cancer trajectory and associations with quality of life. Cancer Epidemiology Biomarkers & Prevention, 18(2), 664-672.
Craig, C.L., Marshall, A. L., Sjöström, M., Bauman, A. E., Booth, M.L., Ainsworth, B. E., …Oja, P. (2003). International Physical Activity Questionnaire (IPAQ): 12-country reliability and validity. Medicine & Science in Sports & Exercise, 35, 1381-1395.
Cramp, F., & Daniel, J. (2008). Exercise for the management of cancer-related fatigue in adults. Cochrane Database of Systematic Reviews (Online), 11 , CD006145
Crouter, S. E., Schneider, P. L., Karabulut, M., & Bassett, D. R. (2003). Validity of 10 electronic pedometers for measuring steps, distance, and energy cost. Medicine and Science in Sports and Exercise, 35(8), 1455-1460.
Danovi, S. A. (2010). Circadian rhythms: In the heat of the night. Nature Reviews Neuroscience, 11(12), 788-789.
De Aguiar, S. S., Bergmann, A., & Mattos, I. E. (2014). Quality of life as a predictor of overall survival after breast cancer treatment. Quality of Life Research, 23(2), 627-637.
Dinger, M. K., Oman, R. F., Taylor, E. L., Vesely, S. K., & Able, J. (2004). Stability and convergent validity of the Physical Activity Scale for the Elderly (PASE). The Journal of Sports Medicine and Physical Fitness, 44(2), 186-192.
Doyle, C., Kushi, L. H., Byers, T., Courneya, K. S., Demark-Wahnefried, W., Grant, B., ... & Andrews, K. S. (2006). Nutrition and physical activity during and after cancer treatment: An American Cancer Society guide for informed choices. CA: A Cancer Journal for Clinicians, 56(6), 323-53.
Duffy, S. A., Khan, M. J., Ronis, D. L., Fowler, K. E., Gruber, S. B., Wolf, G. T., & Terrell, J. E. (2008). Health behaviors of head and neck cancer patients the first year after diagnosis. Head and Neck, 30, 93-102.
Duncan, J. S., Schofield, G., Duncan, E. K., & Hinckson, E. A. (2007). Effects of age, walking speed, and body composition on pedometer accuracy in children. Research Quarterly for Exercise and Sport, 78(5) , 420-428.
Eastman, C. I., Hoese, E. K., Youngstedt, S. D., & Liu, L. (1995). Phase-shifting human circadian rhythms with exercise during the night shift. Physiology & Behavior, 58(6), 1287-1291.
Faul, F., Erdfelder, E., Lang, A. G., & Buchner, A. (2007). G*Power 3: A flexible statistical power analysis program for the social, behavioral, and biomedical sciences. Behavior Research Methods, 39(2), 175-191.
Ferrell, B. R., Hassey-Dow, K., Leigh,S., Ly, J., & Gulasekaram, P. (1995). Quality of life in long-term cancer survivors. Oncology Nursing Forum, 22(6), 915-922.
Fox, S.W. & Lyon, D.E. (2006). Symptom clusters and quality of life in survivors of lung cancer. Oncology Nursing Forum, 33, 931-936.
Freedson, P. S. & Miller, K. (2000). Objective monitoring of physical activity using motion sensors and heart rate. Research Quarterly for Exercise and Sport, 71, s21-s29.
Freeman, J. A., Hobart, J. C., Langdon, D. W., & Thompson, A. J. (2000). Clinical appropriateness: A key factor in outcome measure selection: the 36 item short form health survey in multiple sclerosis. Journal of Neurology, Neurosurgery, & Psychiatry, 68, 150-156.
Fuh, J. L., Wang, S. J., Lu, S. R., Juang, K. D., & Lee, S. J. (2000). Psychometric evaluation of a Chinese (Taiwanese) version of the SF-36 health survey amongst middle-aged women from a rural community. Quality of Life Research, 9, 675-683.
Fulton, J. E., Simons-Morton, D. G., & Galuska, D. A. (2009). Physical activity: An investment that pays multiple health dividends. Archives of Internal Medicine, 169, 2124-2127.
Given, B., Given, C., Azzouz, F., & Stommel, M. (2001). Physical function of elderly cancer patients perior to diagnosis and following initial treatment. Nursing Research, 50, 222-232.
Godin, G., & Shephare, R. J. (1985). A simple method to assess exercise behavior in the community. Canadian Journal of Applied Sport Science, 10, 141-146.
Gosker, H. R., Lencer, N. H. M. K., Franssen, F. M. E., Van Der Vusse, G. J., Wouters, E. F. M., & Schols, A. M. W. J. (2003). Striking similarities in systemic factors contributing to decreased exercise capacity in patients with severe chronic heart failure or COPD. Chest, 123, 1416-1424.
Grutsch, J. F., Ferrans, C., Wood, P. A., Du-Quiton, J., Quiton, D. F., Reynolds, J. L., ... & Hrushesky, W. J. (2011). The association of quality of life with potentially remediable disruptions of circadian sleep/activity rhythms in patients with advanced lung cancer. BMC Cancer, 11(1), 193.
Hagiwara, A., Ito, N., Sawai, K., & Kazuma, K. (2008). Validity and reliability of the Physical Activity Scale for the Elderly (PASE) in Japanese elderly people. Geriatrics & Gerontology International, 8(3), 143-151.
Harrison, S., Hayes, S. C., & Newman, B. (2009). Age-related differences in exercise and quality of life among breast cancer survivors. Medicine and Science in Sports and Exercise, 42(1), 67-74.
Haskell, W. L., Lee, I.M., Pate, R. R., Powell, K. E., Blair, S. N., Franklin, B. A., MacEra, C.A.,...Bauman, A. (2007) Physical activity and public health: Updated recommendation for adults from the American College of Sports Medicine and the American Heart Association. Medicine and Science in Sports and Exercise, 39 (8), 1423-1434.
Hassey-Dow,K., Ferrell,B.R., Haberman,M.(1999).The meaning of QOL in cancer survivors. Oncology Nursing Forum,26(3), 519-528.
Hersen, M. (2006). Clinician''s handbook of child behavioral assessment. Burlington, MA : Elsevier Academic Press.
Husson, O., Mols, F., van de Poll-Franse, L. V., & Thong, M. S. (2015). The course of fatigue and its correlates in colorectal cancer survivors: A prospective cohort study of the PROFILES registry. Supportive Care in Cancer, 23(11), 3361-3371.
IARC (International Agency for Research on Cancer). (2012). Globocan 2012: Estimated Cancer Incidence, Mortality and Prevalence Worldwide in 2012. Retrieved from http://globocan.iarc.fr/Pages/fact_sheets_population.aspx.
Innominato, P. F., Focan, C., Gorlia, T., Moreau, T., Garufi, C., Waterhouse, J., ... & Bjarnason, G. A. (2009). Circadian rhythm in rest and activity: A biological correlate of quality of life and a predictor of survival in patients with metastatic colorectal cancer. Cancer Research, 69(11), 4700-4707.
Innominato, P. F., Giacchetti, S., Bjarnason, G. A., Focan, C., Garufi, C., Coudert, B., ... & Lévi, F. A. (2012). Prediction of overall survival through circadian rest‐activity monitoring during chemotherapy for metastatic colorectal cancer. International Journal of Cancer, 131(11), 2684-2692.
Jenkins, V. A., Bloomfield, D. J., Shilling, V. M., & Edginton, T. L. (2005). Does neoadjuvant hormone therapy for early prostate cancer affect cognition? Results from a pilot study. BJU International, 96(1), 48-53.
Johansen, K. L., Painter, P., Kent-Braun, J. A., Ng, A. V., Carey, S., Da Silva, M., & Chertow, G. M. (2001). Validation of questionnaires to estimate physical activity and functioning in end-stage renal disease. Kidney International, 59, 1121-1127.
Johnson-Kozlow, M., Sallis J. F., Gilpin, E. A., Rock, C. L., & Pierce, J. P:(2006). Comparative validation of the IPAQ and the 7-Day PAR among women diagnosed with breast cancer. International Journal of Behavioral Nutrition and Physical Activity, 3(1), 7.
Jurakić, D., Pedišić, Ž., & Greblo, Z. (2010). Physical activity in different domains and health-related quality of life: A population-based study. Quality of Life Research, 19(9), 1303-1309.
Kim, H. J., Barsevick, A. M., Fang, C. Y., & Miaskowski, C. (2012). Common biological pathways underlying the psychoneurological symptom cluster in cancer patients. Cancer Nursing, 35(6), E1-E20.
Krasnoff, J. B., Vintro, A. Q., Ascher, N. L., Bass, N. M., Dodd, M. J., & Painter, P. L. (2005). Objective measures of health-related quality of life over 24 months post-liver transplantation. Clinical Transplantation, 19, 1-9.
Ku, P. W., Fox, K. R., Chen, L. J., & Chou, P. (2012). Physical activity and depressive symptoms in older adults: 11-year follow-up. American Journal of Preventive Medicine, 42(4), 355-362.
Kwon, S., Hou, N., & Wang, M. (2012). Comparison of physical activity levels between cancer survivors and non-cancer participants in the 2009 BRFSS. Journal of Cancer Survivorship, 6(1) , 54-62.
Laporte, R. E., Montoye. H. J., & Casperson. C. J. (1985). Assessment of physical activity in epidemical research: Problems and prospects. Public Health Reports, 100(2), 131-146.
Li, J. Z. (2014). Circadian rhythms and mood: Opportunities for multi‐level analyses in genomics and neuroscience. Bioessays, 36(3), 305-315.
Lin, C. C., Chang, A. P., Cleeland, C. S., Mendoza, T. R., & Wang, X. S. (2007). Taiwanese version of the MD Anderson symptom inventory: Symptom assessment in cancer patients. Journal of Pain and Symptom Management, 33(2), 180-188.
Lin, C. H., Liao, K. C., Pu, S. J., Chen, Y. C., & Liu, M. S. (2011). Associated factors for falls among the community-dwelling older people assessed by annual geriatric health examinations. PLoS One, 6(4), e18976.
Lin, Y. Y., Lai, Y. F., Lu, H. I., Lai, Y. L., & Lin, C. C. (2013). Physical activity preferences among patients with lung cancer in Taiwan. Cancer Nursing, 36(2), 155-162.
Liou, Y. M., Jwo, C. J., Yao, K. G., Chiang, L. C., Huang, L. H. (2008). Selection of appropriate Chinese terms to represent intensity and types of physical activity terms for use in the Taiwan version of IPAQ. The Journal of Nursing Research, 16, 252-263.
Littner, M., Kushida, C.A., Anderson, W. M., Bailey, D., Berry, R. B., Davila, D. G., ... & Johnson, S. F. (2003). Practice parameters for the role of actigraphy in the study of sleep and circadian rhythms: An update for 2002. Sleep, 26(3), 337-341.
Liu, R. D., Buffart, L. M., Kersten, M. J., Spiering, M., Brug, J., van Mechelen, W., & Chinapaw, M. J. (2011). Psychometric properties of two physical activity questionnaires, the AQuAA and the PASE, in cancer patients. BMC Medical Research Methodology, 11(1), 30.
Loland, N. W. (2002). Reliability of the physical activity scale for the elderly (PASE). European Journal of Sport Science, 2(5), 1-12.
Lowe, S. S., Watanabe, S. M., Baracos, V. E., & Courneya, K. S. (2009). Associations between physical activity and quality of life in cancer patients receiving palliative care: A pilot survey. Journal of Pain and Symptom Management, 38, 785-796.
Luctkar-Flude, M., Groll, D., Woodend, K., & Tranmer, J. (2009). Fatigue and physical activity in older patients with cancer: A six-month follow-up study. Oncology Nursing Forum, 36, 194-202.
Lynn, M. R. (1986). Determination and quantification of content validity. Nursing Research, 35(6), 382-386.
May, A. M., Korstjens, I., van Weert, E., van den Borne, B., Hoekstra-Weebers, J. E., Van Der Schans, C.P.,...Ros, W. J. G. (2009). Long-term effects on cancer survivors’ quality of life of physical training versus physical training combined with cognitive-behavioral therapy: results from a randomized trial. Supportive Care in Cancer, 17, 653-663.
Mazzoccoli, G., Carughi, S., De Cata, A., La Viola, M., & Vendemiale, G. (2005). Melatonin and cortisol serum levels in lung cancer patients at different stages of disease. Medical Science Monitor Basic Research, 11(6), CR284-CR288.
Michael, M. B., & Tannock, I. F. (1998). Measuring health-related quality of life in clinical trials that evaluate the role of chemotherapy in cancer treatment. Canadian Medical Association, 158, 1727-1734.
Ministry of the Interior republic of china (taiwan) (2011). Survey Summary of Women’s Living condition in Taiwan Area, 2011. Retrieved from http://www.moi.gov.tw/stat/english/survey.asp.
Minors, D., Akerstedt, T., Atkinson, G., Dahlitz, M., Folkard, S., Levi, F., ... & Waterhouse, J. (1996). The difference between activity when in bed and out of bed. I. Healthy subjects and selected patients. Chronobiology International, 13(1), 27-34.
Mishra, S. I., Scherer, R. W., Geigle, P. M., Berlanstein, D. R., Topaloglu, O., Gotay, C. C., & Snyder, C. (2012). Exercise interventions on health‐related quality of life for cancer survivors. The Cochrane Library.
Montazeri, A., Harirchi, I., Vahdani, M., Khaleghi, F., Jarvandi, S., Ebrahimi, M., & Haji-Mahmoodi, M. A. N. N. A. N. (2000). The EORTC breast cancer-specific quality of life questionnaire (EORTC QLQ-BR23): Translation and validation study of the Iranian version. Quality of Life Research, 9(2), 177-184.
Moran, D. S., Heled, Y., & Gonzalez, R. R. (2004). Metabolic rate monitoring and energy expenditure prediction using a novel actigraphy method. Medical Science Monitor: International Medical Journal of Experimental and clinical research, 10(11), 117-120.
Mormont, M. C., & Waterhouse, J. (2002). Contribution of the rest-activity circadian rhythm to quality of life in cancer patients. Chronobiology International, 19(1), 313-323.
Mormont, M. C., Waterhouse, J., Bleuzen, P., Giacchetti, S., Jami, A., Bogdan, A., ... & Levi, F. (2000). Marked 24-h rest/activity rhythms are associated with better quality of life, better response, and longer survival in patients with metastatic colorectal cancer and good performance status. Clinical Cancer Research, 6, 3038-3045.
Newman, B., & Newman, P. (2012). Psychoscial theory. In L. S. Ganster (Ed.), Development through life: A psychosocial approach (11th ed., pp.60-85). Belmont, CA : Wadsworth Cengage Learning.
Ngai, S. P., Cheung, R. T., Lam, P. L., Chiu, J. K., & Fung, E. Y. (2012). Validation and reliability of the Physical Activity Scale for the Elderly in Chinese population. Journal of Rehabilitation Medicine, 44(5), 462-465.
Oleson, M. (1990). Subjectively perceived quality of life. Image: Journal of Nursing Scholarship, 22(3), 187-190.
Paraskevi, T. (2012). Quality of life outcomes in patients with breast cancer. Oncology Reviews, 6, 7-10.
Peddle, C. J., Au, H. J., & Courneya, K. S. (2008). Associations between exercise, quality of life, and fatigue in colorectal cancer survivors. Diseases of the Colon & Rectum, 51(8), 1242-1248.
Pereira, M. A., FitzerGerald, S. J., Gregg, E. W., Joswiak, M. L., Ryan, W. J., Suminski, R. R.,...Zmuda, J. M. (1997). A collection of physical activity questionnaires for health-related research. Medicine & Science in Sports & Exercise, 29(6), s1-s205.
Pereira, M. A., Rifas-Shiman, S. L., Kleinman, K. P., Rich-Edwards, J. W., Peterson, K. E., & Gillman, M. W. (2007). Predictors of change in physical activity during and after pregnancy. project viva. American Journal of Preventive Medicine, 32, 312-319.
Physical Activities Guidelines Advisory Committee (2008). Physical Activity Guidelines Advisory Committee Report. Washington (DC): US Department of Health and Human Services.
Powell, S. M. & Rowlands, A. V.(2004). Intermonitor variability of the RT3 accelerometer during typical physical activities. Medicine and Science in Sports and Exercise, 36, 324-330.
Powell, S. M., Jones, D. I. & Rowlands, A. V.(2003). Technical variability of the RT3 accelerometer. Medicine and Science in Sports and Exercise, 35, 1773-1778.
Preacher, K. J., & Hayes, A. F. (2008). Asymptotic and resampling strategies for assessing and comparing indirect effects in multiple mediator models. Behavior research methods, 40(3), 879-891.
Reiser, L. M., & Schlenk, E. A. (2009). Clinical use of physical activity measures. Journal of the American Academy of Nurse Practitioners, 21, 87-94.
Rich, T. A. (2007). Symptom clusters in cancer patients and their relation to EGFR ligand modulation of the circadian axis. The Journal of Supportive Oncology, 5(4), 167-174.
Rich, T., Innominato, P. F., Boerner, J., Mormont, M. C., Iacobelli, S., Baron, B., ... & Lévi, F. (2005). Elevated serum cytokines correlated with altered behavior, serum cortisol rhythm, and dampened 24-hour rest-activity patterns in patients with metastatic colorectal cancer. Clinical Cancer Research, 11(5), 1757-1764.
Rowland, J. H., Hewitt, M., & Ganz, P. A. (2006). Cancer survivorship: A new challenge in delivering quality cancer care. Journal of Clinical Oncology, 24(32), 5101-5104.
Rowlands, A. V., Thomas, P. W. M., Eston, R. G. & Topping, R. (2004). Validation of the RT3 triaxial accelerometer for the assessment of physical activity. Medicine and Science in Sports and Exercise, 36, 518-524.
Saba, V., Pocklington, D. B., & Miller, K. P. (Eds.). (2012). Nursing and computers: An anthology, 1987–1996. Springer Science & Business Media.
Sallis, J. F., Haskell, W. L., Wood, P. D., Fortmann, S.P., Rogers, T., Blair, S. N., & Paffenbarger, R. S. (1985). Physical activity assessment methodology in five-city project. American Journal of Epidemiology, 121, 91-106.
Santa Mina, D., Guglietti, C. L., Alibhai, S. M., Matthew, A. G., Kalnin, R., Ahmad, N., ... & Trachtenberg, J. (2014). The effect of meeting physical activity guidelines for cancer survivors on quality of life following radical prostatectomy for prostate cancer. Journal of Cancer Survivorship, 8(2), 190-198.
Sapp, A. L., Trentham‐Dietz, A., Newcomb, P. A., Hampton, J. M., Moinpour, C. M., & Remington, P. L. (2003). Social networks and quality of life among female long‐term colorectal cancer survivors. Cancer, 98(8), 1749-1758.
Saxton, J. M., Scott, E. J., Daley, A. J., Woodroofe, M. N., Mutrie, N., Crank, H., ... & Coleman, R. E. (2014). Effects of an exercise and hypocaloric healthy eating intervention on indices of psychological health status, hypothalamic-pituitary-adrenal axis regulation and immune function after early-stage breast cancer: A randomised controlled trial. Breast Cancer Research, 16:R39.
Schmitz, K. H., Courneya, K. S., Matthews, C, Demark-Wahnefried, W, Galvao, D. A., Pinto, B. M., ...& Schwartz A. L. (2010). American College of Sports Medicine roundtable on exercise guidelines for cancer survivors. Medicine Science Sports Exercise. 42(7), 1409-1426.
Schmidt, M. E., Chang-Claude, J., Vrieling, A., Heinz, J., Flesch-Janys, D., & Steindorf, K. (2012). Fatigue and quality of life in breast cancer survivors: temporal courses and long-term pattern. Journal of Cancer Survivorship, 6(1), 11-19.
Schroder, E. A., & Esser, K. A. (2013). Circadian Rhythms, skeletal muscle molecular clocks and exercise. Exercise and sport sciences reviews, 41(4), 224-229.
Schult, A. J., Schonten, E. G., Westerterp, K. R., & Saris, W. H. M. (1997). Validity of the Physical Activity Scale for the Elderly (PASE): According to energy expenditure assessed by the doubly labeled water method. Journal of Clinical Epidemiology, 50, 541-546.
Schwartz, C. E., & Sprangers, M. A. (2002). An introduction to quality-of-life Assessment in oncology: The value of measuring patient-reported outcomes. American Journal of Managed Care, 8(18; SUPP), S550-S559.
Sephton, S., & Spiegel, D. (2003). Circadian disruption in cancer: A neuroendocrine-immune pathway from stress to disease? Brain, Behavior, and Immunity, 17(5), 321-328.
Siegel, R., DeSantis, C., Virgo, K., Stein, K., Mariotto, A., Smith, T., ... & Ward, E. (2012). Cancer treatment and survivorship statistics, 2012. CA: a Cancer Journal for Clinicians, 62(4), 220-241.
Sobel, M. E. (1982). Asymptotic confidence intervals for indirect effects in structural equation models. Sociological Methodology, 13(1982), 290-312.
Strohle, A. (2009). Physical activity, exercise, depression and anxiety disorders. Journal of Neural Transmission, 116(6), 777-784.
Su, C. C., Lee, K. D., Yeh, C. H., Kao, C. C., & Lin, C. C. (2014). Measurement of physical activity in cancer survivors: A validity study. Journal of Cancer Survivorship, 8(2), 205-212.
Tanha, T., Wollmer, P., Thorsson, O., Karlsson, M. K., Linden, C., Andersen, L. B., & Dencker, M. (2011). Lack of physical activity in young children is related to higher composite risk factor score for cardiovascular disease. Acta Paediatrica, International Journal of Paediatrics, 100, 717-721.
Taiwan Cancer Registry (2009). Cancer Survival Rates in Taiwan. Retrieved from http://tcr.cph.ntu.edu.tw/main.php?Page=A5B3
Terwee, C. B., Mokkink, L. B., van Poppel, M. N. M., Chinapaw, M. J., van Mechelen, W., & de Vet, H. C. W. (2010). Qualitative attributes and measurement properties of physical activity questionnaires: A checklist. Sports Medicine, 40(7), 525-537.
Thraen-Borowski, K. M., Trentham-Dietz, A., Edwards, D. F., Koltyn, K. F., & Colbert, L. H. (2013). Dose–response relationships between physical activity, social participation, and health-related quality of life in colorectal cancer survivors. Journal of Cancer Survivorship, 7(3), 369-378.
Tien, Y.-H., & Lin, K.-F. (2008). The relationships between physical activity and static balance in elderly people. Journal of Exercise Science and Fitness, 6(1), 21-25.
Tryon, W. W. (2005). The reliability and validity of two ambulatory monitoring actigraphs. Behavior Research Methods, 37(3), 492-497.
Tudor-Locke, C. E., & Myers, A. M. (2001). Methodological considerations for researchers and practitioners using pedometers to measure physical (ambulatory) activity. Research Quarterly for Exercise and Sport, 72(1), 1-12.
U. S. Department of Health and Human Services (1998). Physical activity and health: a report of the Surgeon General. Sudbury, MA: Jones and Bartlett Publishers.
van Poppel, M. N., Chinapaw, M. J., Mokkink, L. B., Van Mechelen, W., & Terwee, C. B. (2010). Physical activity questionnaires for adults. Sports Medicine, 40(7), 565-600.
Vaughan, K., & Miller, W. C. (2013). Validity and reliability of the Chinese translation of the Physical Activity Scale for the Elderly (PASE). Disability and Rehabilitation, 35(3), 191-197.
Ware, J. E., & Sherbourne, C. D. (1992). The MOS 36-item Short Form Health Survey (SF-36): Conceptual framework and item selection. Medication Care, 30, 473-483.
Washburn, R .A., McAuley, E., Katula, J., Mihalko, S. L., & Boileau, R. A. (1999). The Physical Activity Scale for the Elderly (PASE): Evidence for validity. Journal of Clinical Epidemiology, 52, 643-651.
Washburn, R. A., Smith, K. W., Jette, A. M., & Janney, C. A. (1993). The Physical Activity Scale for the Elderly (PASE): Development and evaluation. Journal of Clinical Epidemiology, 46(2), 153-162.
Washburn, R.A., & Ficker, J.L. (1999). Physical Activity Scale for the Elderly (PASE): The relationship with activity measured by a portable accelerometer. Journal of Sports Medicine and Physical Fitness, 39(4), 336-340.
Waterhouse, J., Edwards, B., Bedford, P., Hughes, A., Robinson, K., Nevill, A., ... & Reilly, T. (2004). Thermoregulation during mild exercise at different circadian times. Chronobiology International, 21(2), 253-275.
Weaver, K. E., Forsythe, L. P., Reeve, B. B., Alfano, C. M., Rodriguez, J. L., Sabatino, S. A., ... & Rowland, J. H. (2012). Mental and physical health–related quality of life among US cancer survivors: Population estimates from the 2010 National Health Interview Survey. Cancer Epidemiology Biomarkers & Prevention, 21(11), 2108-2117.
Weinert, D., & Waterhouse, J. (2007). The circadian rhythm of core temperature: Effects of physical activity and aging. Physiology & behavior, 90(2), 246-256.
Weir, J. P. (2005). Quantifying test–retest reliability using the intraclass correlation coefficient and the SEM. Journal of Strength and Conditioning Research, 19, 231-240.
WHOQOL group. (1995). The World Health Organization quality of life assessment (WHOQOL): Position paper from the World Health Organization. Social science & medicine, 41(10), 1403-1409.
World Health Organization (2010). Global Recommendations on Physical Activity for Health. Retrieved from http://www.who.int/dietphysicalactivity/factsheet_recommendations/en/
Xavier, F. M., Ferraz, M., Marc, N., Escosteguy, N. U., & Moriguchi, E. H. (2003). Elderly people s definition of quality of life. Revista Brasileira de Psiquiatria, 25(1), 31-39.
Yamanaka, Y., Honma, K. I., Hashimoto, S., Takasu, N., Miyazaki, T., & Honma, S. (2006). Effects of physical exercise on human circadian rhythms. Sleep and Biological Rhythms, 4(3), 199-206.
Yates, J. W., Chalmer, B., & McKegney, F. P. (1980). Evaluation of patients with advanced cancer using the Karnofsky performance status. Cancer, 45(8), 2220-2224.
Zeng, Y., Huang, M., Cheng, A. S., Zhou, Y., & So, W. K. (2014). Meta-analysis of the effects of exercise intervention on quality of life in breast cancer survivors. Breast Cancer, 21(3), 262-274.
Zhao, Z. Y., Xie, Y., Fu, Y. R., Bogdan, A., & Touitou, Y. (2002). Aging and the circadian rhythm of melatonin: A cross-sectional study of Chinese subjects 30-110 yr of age. Chronobiology International, 19(6), 1171-1182.
QRCODE
 
 
 
 
 
                                                                                                                                                                                                                                                                                                                                                                                                               
第一頁 上一頁 下一頁 最後一頁 top
系統版面圖檔 系統版面圖檔