(100.26.179.251) 您好!臺灣時間:2021/04/15 16:36
字體大小: 字級放大   字級縮小   預設字形  
回查詢結果

詳目顯示:::

我願授權國圖
: 
twitterline
研究生:鄭有妏
研究生(外文):You-Wun Jheng
論文名稱:接受紫杉醇治療的乳癌婦女周邊神經病變、功能狀態 與生活品質之相關性探討
論文名稱(外文):Exploring the relationship between peripheral neuropathy, functional status and quality of life in women with breast cancer after taxane treatment
指導教授:王雅容王雅容引用關係
指導教授(外文):Ya-Jung Wang
學位類別:碩士
校院名稱:國立陽明大學
系所名稱:臨床護理研究所
學門:醫藥衛生學門
學類:護理學類
論文種類:學術論文
論文出版年:2016
畢業學年度:104
語文別:中文
論文頁數:151
中文關鍵詞:乳癌婦女紫杉醇治療周邊神經病變功能狀態生活品質
外文關鍵詞:Breast cancerfunctional statusperipheral neuropathyquality of lifetaxane chemotherapy
相關次數:
  • 被引用被引用:1
  • 點閱點閱:320
  • 評分評分:系統版面圖檔系統版面圖檔系統版面圖檔系統版面圖檔系統版面圖檔
  • 下載下載:0
  • 收藏至我的研究室書目清單書目收藏:1
背景
乳癌位居台灣女性癌症發生率之冠,死亡率為第四;五年存活率可達89%以上,現今紫杉醇治療的助益已被證實,但伴隨而來的副作用影響乳癌婦女的生活品質。其中,周邊神經病變是常見卻也易被長期忽視的副作用,影響個人的生理、心理與社會功能狀態,甚至延誤或中斷治療。國外已有探討周邊神經病變造成癌症病人各方面之影響,而國內尚無女性乳癌族群本土化資料。
目的
本研究旨在探討乳癌婦女接受紫杉醇治療後引發周邊神經病變、功能狀態與生活品質的現況,分析各研究變項間之相關性,並了解生活品質的預測因子。
方法
採橫斷面研究設計,以立意取樣於台北市某醫學中心門診、化學注射室及一般外科病房,使用結構式問卷進行資料收集,研究對象為至少經歷過一次以上紫杉醇治療的乳癌婦女,共收案123人。研究工具包括個人基本資料表、病人神經毒性問卷、臨床版神經病變量表、周邊神經病變量表與乳癌治療功能性評估。資料以SPSS 20.0統計套裝軟體建檔,採描述性及推論性統計分析。
結果

研究結果顯示研究對象接受docetaxel藥物為主要配方占最大宗(88.6%),平均年齡為51.50±9.74歲。周邊神經病變的現況,一、主觀評估方面:71.5%有感覺症狀,66.7%有運動症狀,將近半數呈輕微程度,僅4.9%至7.3%為嚴重程度;二、客觀評估方面:87.0%發生周邊神經病變,以針刺感與震顫感變弱為主。腳的功能狀態變差比手嚴重,且麻木感比刺痛感嚴重。生活品質程度在中等以上。主觀周邊神經病變與功能狀態呈顯著正相關(rho值為0.674,p值小於0.001);與生活品質呈顯著負相關(rho值為-0.302,p值為0.001)。客觀周邊神經病變與功能狀態亦呈顯著正相關(r值為0.633,p值小於0.001);與生活品質呈顯著負相關(r值為-0.364,p值小於0.001)。功能狀態與生活品質呈顯著負相關(r值為-0.490,p值小於0.001)。經階層式迴歸分析得知,接觸化學物品風險、因病辭去工作、合併慢性病、嚴重的主觀周邊神經病變運動症狀與低功能狀態,五個變項為降低生活品質之預測因子,總解釋變異量為37.6%。
結論
乳癌婦女接受紫杉醇治療後會引發周邊神經病變,影響功能狀態與生活品質呈負向趨勢,護理人員應搭配主客觀工具評估周邊神經病變,期望達到早期發現,及時處置之成效,進而提升個案化療後的整體生活品質。

Background: Breast cancer is the most frequent female cancer in Taiwan, while its mortality rate is the forth and overall five year survival is 89%. The taxane including paclitaxel and docetaxel is benefitical for breast cancer survivorship demonstrated by numerous randomized trials. However, side effects from taxane because chemotherapy diminished these women’s quality of life. Taxane-induced peripheral neuropathy (TIPN) is a common side effects and negatively influences women’s physical, psychological and social status. There are many studies to survey the phenomenon of TIPN in other countries, but no study to investigate its impact on Taiwanese women with breast cancer up to now.
Purpose: The primary purpose of this study was to investigate the distribution and relationship among peripheral neuropathy, functional status and quality of life in women with breast cancer after taxane treatment. Additionally, it was also to examine the predicting factors of quality of life in this population.
Methods: This study utilized a cross-sectional study design and purposive sampling. A total of 123 women with breast cancer received at least one treatment with taxane were recruited in this study from a medical center in northern Taiwan. Instruments included demographic and clinical characteristic questionnaires, Patient Neurotoxicity Questionnaire, Total Neuropathy Score-clinical version, Peripheral Neuropathy Scale and Functional Assessment for Cancer Treatment-Breast.SPSS 20.0 software was used for data entry and analysis. The data were analyzed utilizing descriptive statistics and inferential analyses.
Results: Majority of the participants received docetaxel therapy. The average age was 51.50 (SD=9.74). The TIPN subjective measure found sensory symptoms and motor symptoms were 71.5% and 66.7%, respectively. Nearly half of the participants were with slight symptoms but only 4.9 to 7.3% of them were with a severe degree. The objective method indicated that 87.0% had peripheral neuropathy. Moreover, two of the most common symptoms were the deterioration of sensation on pinprick and vibration tests. The domain of functional status revealed that the symptoms in feet were more serious than they were in hands; numbness was more severe than tingling. The quality of life in this study was above the moderate level. There was a positive correlation between subjective TIPN and functional status (rho=0.674, p<0.001), a negative correlation between subjective TIPN and quality of life (rho=-0.302, p=0.001), a positive correlation between objective TIPN and functional status (r=0.633, p<0.001), and then a negative correlation between objective TIPN and quality of life (rho=-0.364, p<0.001). In additional, there was a negative correlation between functional status and quality of life (r=-0.490, p<0.001). The hierarchical multiple regression analysis detected that the risk of exposure to chemical materials, quit their job due to illness, with chronic diseases, the severe degree of subjective TIPN motor symptoms and poor functional status were the predictors of negative quality of life. The aforementioned factors explained 37.6% of the variance of quality of life.
Conclusion: Women with breast cancer after taxane treatment induced peripheral neuropathy negatively affected functional status and quality of life. In order to improve patients’ quality of life oncology nurses need to have skills utilizing the TIPN subjective and objective tools to early detect and timely manage the TIPN.


目次
致謝 i
中文摘要 ii
Abstract iv
目 錄 v
表目錄 viii
圖目錄 ix
第一章 緒論 1
第一節 研究動機與重要性 1
第二節 研究目的 5
第二章 文獻查證 6
第一節 乳癌 6
第二節 周邊神經病變 13
第三節 功能狀態與相關研究 29
第四節 生活品質與相關研究 35
第五節 周邊神經病變、功能狀態與生活品質的關係 45
第三章 研究方法 47
第一節 研究設計 47
第二節 研究架構 48
第三節 名詞界定 49
第四節 研究假設 52
第五節 研究對象與抽樣方法 53
第六節 研究工具 54
第七節 資料收集過程 59
第八節 資料分析與統計方法 60
第九節 研究倫理 63
第四章 研究結果 64
第一節 接受紫杉醇治療的乳癌婦女之個人基本屬性分布情形 64
第二節 乳癌婦女接受紫杉醇治療引發周邊神經病變之現況 71
第三節 接受紫杉醇治療的乳癌婦女之功能狀態與生活品質分布情形 75
第四節 乳癌婦女接受紫杉醇治療後周邊神經病變、功能狀態與生活     品質之關係 78
第五節 乳癌婦女接受紫杉醇治療後生活品質之預測因子 95
第五章 討論 100
第一節 探討乳癌婦女接受紫杉醇治療之個人基本屬性的現況 100
第二節 探討乳癌婦女接受紫杉醇治療引發周邊神經病變的現況 103
第三節 探討接受紫杉醇治療的乳癌婦女之功能狀態與生活品質分布     情形 106
第四節 探討乳癌婦女紫杉醇治療後周邊神經病變、功能狀態與生活     品質之關係 109
第五節 探討乳癌婦女接受紫杉醇治療後生活品質之預測因子 114
第六章 結論與建議 116
第一節 結論 116
第二節 研究限制 119
第三節 建議與應用 120
參考文獻 123
中文部分 123
英文部分 126
附 錄 143
附錄一 個人基本資料表 143
附錄二 病人神經毒性問卷 145
附錄三 臨床版神經病變總評分 146
附錄四 周邊神經病變量表 147
附錄五 乳癌治療功能性評估 148

表目次
表2-1 TNM系統分類細則 8
表2-2 神經病變嚴重度評估量表等級意義 22
表3-1 本研究使用之研究工具綜整表 57
表3-2 各變項分類、性質與描述性統計方法 61
表3-3 推論性統計分析方式 62
表4-1 乳癌婦女接受紫杉醇治療之人口學屬性分布情形 66
表4-2 乳癌婦女接受紫杉醇治療之生活習慣變項分布情形 68
表4-3 乳癌婦女接受紫杉醇治療之醫療相關資訊分布情形 69
表4-4 病人神經毒性問卷主觀測量研究對象周邊神經病變之狀態 72
表4-5 臨床版神經病變總評分客觀測量研究對象周邊神經病變之狀態74
表4-6 本研究測量周邊神經病變各量表之內在一致性信度 74
表4-7 接受紫杉醇治療的乳癌婦女功能狀態與生活品質之得分情形 77
表4-8 本研究測量功能狀態與生活品質之內在一致性信度 77
表4-9 「病人神經毒性問卷 (PNQ)」主觀評估周邊神經病變的影響因素
79
表4-10「臨床版神經病變總評分 (TNSc)」客觀評估周邊神經病變的 
    影響因素 85
表4-11「周邊神經病變量表(PNS)」評估功能狀態的影響因素 88
表4-12「乳癌治療功能性評估 (FACT-B)」評估生活品質的影響因素     91
表4-13 主客觀評估周邊神經病變、功能狀態與生活品質之相關性分析     94
表4-14 接受紫杉醇治療乳癌婦女相關係數矩陣圖 96
表4-15 四層面階層式迴歸分析報表 98
表4-16 接受紫杉醇治療乳癌婦女對生活品質的預測因子之階層式迴歸
    摘要表 99


圖目次
圖3-1 研究架構圖 48
圖4-1 研究參與者招募流程圖 65





中文部分
史麗珠(2013)。進階應用生物統計學:連續資料分析(含SPSS使用說明)(第二版,頁30)。台北市:學富文化。〔See, L. C. (2013). Advanced applications biostatistics: Continuous data analysis (Including instructions for SPSS) (2nd ed., pp. 30). Taipei City, Taiwan, ROC: PRO-ED publishing.〕
行政院主計總處(2015,9月25日)。103年家庭收支調查報告。2016年4月28日取自https://www.dgbas.gov.tw/ct.asp?xItem=19882&CtNode=3101&mp=1〔Directorate-General of Budget, Accounting and Statistics, Executive Yuan, Taiwan, R.O.C. (2015, September 25). Report on the survey of family income and expenditure, 2014. Retrieved from https://www.dgbas.gov.tw/ct.asp?xItem=19882&CtNode=3101&mp=1〕
吳明隆、張毓仁(2014)。 SPSS(PASW)與統計應用分析Ⅰ(初版)。台北市:五南圖書出版股份有限公司。〔Wu, M. L., Chang, Y. J. (2014). SPSS (PASW) and statistical analysis application Ⅰ (1st ed.). Taipei City, Taiwan, ROC: Wu-Nan Book I
李作英、葉美玲(2011)。乳癌發生之人口學因子與風險研究。領導護理,12(3), 26-37。〔Lee, T. Y., Yeh, M. L. (2011). A study of the demographic factor on the risk of breast cancer. Leadership Nursing, 12(3), 26-37.〕
李佩珊、李絳桃、黃久美、李奇龍(2006)。更年期婦女之更年期態度、更年期症狀與憂鬱情緒之相關性研究。實證護理,2(2), 156-165。doi: 10.6225/jebn.2.2.156〔Lee, P. S., Lee, J. T., Huang, C. M., Lee, C. L. (2006). The relationship between menopause attitude, climacteric symptoms and depression in women undergoing menopause. Journal of Evidence-Based Nursing, 2(2), 156-165. ido: 10.6225/JEBN.2.2.156〕
林璟宏(2013)。乳癌的化學治療。臺灣醫學,17(4),404-411。〔Lin, C. H. (2013). Chemotherapy in breast cancer. Formosan Journal of Medicine, 17(4), 404-411.〕
姚開屏(2002)。台灣版世界衛生組織生活品質問卷之發展與應用。臺灣醫學, 6(2),193-200。〔Yao, K. P. (2002). Development and applications of the WHOQOL-Taiwan version. Formosan Journal of Medicine, 6(2), 193-200.〕
姜紹青(2006)。抗癌化學藥物治療原則簡介。腫瘤護理雜誌,6(1),1-8。 〔Chiang, S. C. (2006). Introduction to the principles of anticancer chemotherapy treatment. The Journal of Oncology Nursing, 6(1), 1-8.〕
國家衛生研究院(2004,10月)。乳癌診斷與治療共識。2015年8月20日取自http://www.nhri.org.tw/NHRI_ADM/userfiles/file/tcog/breast_II.pdf 〔National health research institutes (2004, October). The consensus of diagnosis and treatment for breast cancer. Retrieved August 20, 2015 from http://www.nhri.org.tw/NHRI_ADM/userfiles/file/tcog/breast_II.pdf〕
張慈惠、黃秀梨(2000)。生活品質評量之臨床應用。臺灣醫學,4(1),86-90。〔Chang, T. H., & Hwang, S. L. (2000). Clinical application of assessment quality of life. Formosan Journal of Medicine, 4(1), 86-90.〕
陳欣妤、鄭淨黛(2010)。化學治療引發周邊神經病變案例報告及文獻回顧。當代醫學,37(11),874-878。 〔Chen, H. Y., & Cheng, C. T. (2010). Chemotherapy induced peripheral neuropathy: Case report and literature review. Contemporary Medical, 37(11), 874-878.〕
陳美碧、謝麗鳳、林惠蘭、李淑貞、林純如、蔡欣玲(2004)。癌症病人之生活品質及其預測因子。榮總護理,21(4),352-362。doi: 10.6142/vghn.21.4.352〔Chen, M. B., Hsieh, L. F., Lin, H. L., Lee, S. C., Lin, C. R., Tsai, S. L. (2004). Predicting factors on quality of life in cancer patients. Taipei Veterans Genera l Hospital Nursing, 21(4). 352-362. ido: 10.6142/VGHN.21.4.352〕
蔡盈盈、張巍鐘、陸汝斌、曹朝榮(2007)。乳癌患者主要照顧者之因應、社會支持與生活品質。臺灣精神醫學, 21(1), 43-52。〔Tsai, Y. Y., Chang, W. C., Lu, R. B., Tsao, C. J. (2007). Coping, Social Support, and Quality of Life among Primary Caregivers of Patients with Breast Cancer. Taiwanese Journal of Psychiat ry, 21(1). 43-52.〕
蔡婷芳(2008)。 肺癌病患接受化學治療引發周邊神經病變及其對情緒與睡眠品質的影響。 (碩士論文) 。取自臺灣碩博士論文知識加值系統。(系統編號:419.6001M97-1) 〔Tsai, T. F. (2008). Impact of chemotherapy-induced peripheral neuropathy on mood and quality of sleep in patients with lung cancer. (Master thesis). Retrieved from National Digital Library of Theses and Dissertations in Taiwan. (order No. 419.6001M97-1)〕
衛生福利部國民健康署(2015,4月29日)。民國101年癌症登記報告。2015年8月20日取自http://www.hpa.gov.tw/BHPNet/Web/Stat/StatisticsShow.aspx?No=201504290001〔Ministry of Health and Welfare Health Promotion Administration, Taiwan, ROC (2015, April 29). Cancer registry annual report, 2012: Taiwan. Retrieved August 20, 2015 from http://www.hpa.gov.tw/BHPNet/Web/Stat/StatisticsShow.aspx?No=201504290001〕
衛生福利部統計處(2015,4月13日)。民國101年死因統計年報。2015年8月20日取自http://www.mohw.gov.tw/cht/DOS/Statistic.aspx?f_list_no=312&fod_list_no=2747 〔Ministry of Health and Welfare Department of Statistics, Taiwan, R.O.C. (2015, April 13). Death statistical annual report, 2012. Retrieved August 20, 2015 from http://www.mohw.gov.tw/cht/DOS/Statistic.aspx?f_list_no=312&fod_list_no=2747〕
盧伶君(2012)。大腸直腸癌病人因化學治療引起之周邊神經性疼痛、日常活動功能、情緒及生活品質之相關性研究。 (碩士論文)。取自臺灣碩博士論文知識加值系統。(系統編號:419.6067M101-35)〔Lu, L. C. (2012). The relationships of chemotherapy induced peripheral neuropathic pain, activities of daily lives, mood, and quality of Life in patient with colorectal cancers. (Master thesis). Retrieved from National Digital Library of Theses and Dissertations in Taiwan. (order No. 419.6067M101-35)〕

英文部分
Aaronson, N. K. (1990). Quality of life research in cancer clinical trials: A need for common rules and language. Oncology (Williston Park, N.Y.), 4(5), 59-66.
Aaronson, N. K., Ahmedzai, S., Bergman, B., Bullinger, M., Cull, A., Duez, N. J., . . . de Haes, J. C. (1993). The European Organization for Research and Treatment of Cancer QLQ-C30: A quality-of-life instrument for use in international clinical trials in oncology. Journal of the National Cancer Institute, 85(5), 365-376.
Aaronson, N. K., Bakker, W., Stewart, A. L., Van Dam, F., Zandwijk, N., Yarnold, J. R.,…… Kirkpatrick, A. (1988). Multidimensional approaches to the measurement of quality of life in lung cancer clinical trials. In N. K. Aaronson & J. Beckmann (Eds.), The quality of life of cancer patients (pp. 63-82). New York, NY: Raven Press.
Albain, K. S., Nag, S. M., Calderillo-Ruiz, G., Jordaan, J. P., Llombart, A. C., Pluzanska, A., . . . O'Shaughnessy, J. (2008). Gemcitabine plus paclitaxel versus paclitaxel monotherapy in patients with metastatic breast cancer and prior anthracycline treatment. Journal of Clinical Oncology, 26(24), 3950-3957. doi: 10.1200/jco.2007.11.9362
Almadrones, L., Armstrong, T., Gilbert, M., & Schuwartz, B. (2002). Chemotherapy- induced neurotoxicity: Current trends in management. Philadelphia, PA: Phillips Group Oncology Communications.
Almadrones, L., McGuire, D. B., Walczak, J. R., Florio, C. M., & Tian, C. (2004). Psychometric evaluation of two scales assessing functional status and peripheral neuropathy associated with chemotherapy for ovarian cancer: A gynecologic oncology group study. Oncology Nursing Forum, 31(3), 615-623. doi: 10.1188/04.ONF.615-623
American Cancer Society. (2013). Breast cancer facts & figures 2013-2014. Retrieved April 5, 2015 from http://www.cancer.org/research/cancerfactsstatistics/breast-cancer-facts-figures
American Cancer Society. (2015, August). Breast Cancer. Retrieve August 25, 2015 from http://www.cancer.org/cancer/breastcancer/detailedguide/breast-cancer-treating-general-info
American Joint Committee on Cancer. (2009). AJCC Cancer Staging Manual. Retrieve August 25, 2015 from https://cancerstaging.org/references-tools/deskreferences/Pages/default.aspx
Anderson, K. L., & Burckhardt, C. S. (1999). Conceptualization and measurement of quality of life as an outcome variable for health care intervention and research. Journal of Advanced Nursing, 29(2), 298-306.
Argyriou, A. A., Briani, C., Cavaletti, G., Bruna, J., Alberti, P., Velasco, R., . . . Kalofonos, H. P. (2013). Advanced age and liability to oxaliplatin-induced peripheral neuropathy: Post hoc analysis of a prospective study. European Journal of Neurology, 20(5), 788-794. doi: 10.1111/ene.12061
Argyriou, A. A., Koltzenburg, M., Polychronopoulos, P., Papapetropoulos, S., & Kalofonos, H. P. (2008). Peripheral nerve damage associated with administration of taxanes in patients with cancer. Critical Reviews in Oncology/Hematology, 66(3), 218-228. doi: 10.1016/j.critrevonc.2008.01.008
Armstrong, T., Almadrones, L., & Gilbert, M. R. (2005). Chemotherapy-induced peripheral neuropathy. Oncology Nursing Forum, 32(2), 305-311. doi: 10.1188/05.ONF.305-311
Avis, N. E., Crawford, S., & Manuel, J. (2005). Quality of life among younger women with breast cancer. Journal of Clinical Oncology, 23(15), 3322-3330.
Awadalla, A. W., Ohaeri, J. U., Gholoum, A., Khalid, A. O. A., Hamad, H. M. A., & Jacob, A. (2007). Factors associated with quality of life of outpatients with breast cancer and gynecologic cancers and their family caregivers: A controlled study. BioMed Central Cancer, 7, 102-102.
Bakitas, M. A. (2007). Background noise: The experience of chemotherapy-induced peripheral neuropathy. Nursing Research, 56(5), 323-331. doi: 10.1097/01.nnr.0000289503.22414.79
Becker, H., Kang, S. J., & Stuifbergen, A. (2012). Predictors of quality of life for long-term cancer survivors with preexisting disabling conditions. Oncology Nursing Forum, 39(2), 122-131.
Bergmann, T., Gréen, H., Brasch-Andersen, C., Mirza, M., Herrstedt, J., Hølund, B., . . . Peterson, C. (2011). Retrospective study of the impact of pharmacogenetic variants on paclitaxel toxicity and survival in patients with ovarian cancer. European Journal of Clinical Pharmacology, 67(7), 693-700. doi: 10.1007/s00228-011-1007-6
Bhatnagar, B., Gilmore, S., Goloubeva, O., Pelser, C., Medeiros, M., Chumsri, S., . . . Bao, T. (2014). Chemotherapy dose reduction due to chemotherapy induced peripheral neuropathy in breast cancer patients receiving chemotherapy in the neoadjuvant or adjuvant settings: A single-center experience. Springerplus, 3(366), 1-6. doi: 10.1186/2193-1801-3-366
Bhopal, R. S. (2002). Concepts of epidemiology: An integrated introduction to the ideas, theories, principles and methods of epidemiology (1st ed.). New York, NY: Oxford University Press.
Binner, M., Ross, D., & Browner, I. (2011). Chemotherapy-induced peripheral neuropathy: Assessment of oncology nurses' knowledge and practice. Oncology Nursing Forum, 38(4), 448-454. doi: 10.1188/11.ONF.448-454
Blum, J. L., & O'Shaughnessy, J. A. (2006). Capecitabine/Taxane combination therapy: Evolving clinical utility in breast cancer. Clinical Breast Cancer, 7(1), 42-50. doi: 10.3816/CBC.2006.n.012
Brady, M. J., Cella, D. F., Mo, F., Bonomi, A. E., Tulsky, D. S., Lloyd, S. R., . . . Shiomoto, G. (1997). Reliability and validity of the Functional Assessment of Cancer Therapy-Breast quality-of-life instrument. Journal of Clinical Oncology, 15(3), 974-986.
Brem, S., & Kumar, N. B. (2011). Management of treatment-related symptoms in patients with breast cancer. Clinical Journal of Oncology Nursing, 15(1), 63-71. doi: 10.1188/11.CJON.63-71
Browall, M. M., Ahlberg, K. M., Persson, L. G., Karlsson, P. O., & Danielson, E. B. (2008). The impact of age on Health-Related Quality of Life (HRQoL) and symptoms among postmenopausal women with breast cancer receiving adjuvant chemotherapy. Acta Oncologica (Stockholm, Sweden), 47(2), 207-215. doi: 10.1080/02841860701621258
Caceres, B. A. (2015). King’s theory of goal attainment: Exploring functional status. Nursing Science Quarterly, 28(2), 151-155. doi: 10.1177/0894318415571601
Calhoun, E. A., Welshman, E. E., Chang, C. H., Lurain, J. R., Fishman, D. A., Hunt, T. L., & Cella, D. (2003). Psychometric evaluation of the functional assessment of cancer therapy/Gynecologic Oncology Group-Neurotoxicity (Fact/GOG-Ntx) questionnaire for patients receiving systemic chemotherapy. International Journal of Gynecological Cancer, 13(6), 741-748. doi: 10.1111/j.1525-1438.2003.13603.x
Carlson, K., & Ocean, A. J. (2011). Peripheral neuropathy with microtubule-targeting agents: Occurrence and management approach. Clinical Breast Cancer, 11(2), 73-81. doi: 10.1016/j.clbc.2011.03.006
Cavaletti, G., Cornblath, D. R., Merkies, I. S. J., Postma, T. J., Rossi, E., Frigeni, B., . . . Valsecchi, M. G. (2013). The chemotherapy-induced peripheral neuropathy outcome measures standardization study: From consensus to the first validity and reliability findings. Annals of Oncology, 24(2), 454-462. Doi: 10.1093/annonc/mds329
Cavaletti, G., Frigeni, B., Lanzani, F., Mattavelli, L., Susani, E., Alberti, P., . . . Bidoli, P. (2010). Chemotherapy-induced peripheral neurotoxicity assessment: A critical revision of the currently available tools. European Journal of Cancer, 46(3), 479-494. doi: 10.1016/j.ejca.2009.12.008
Cavaletti, G., Frigeni, B., Lanzani, F., Piatti, M., Rota, S., Briani, C., . . . Italian, N. G. (2007). The total neuropathy score as an assessment tool for grading the course of chemotherapy-induced peripheral neurotoxicity: Comparison with the national cancer institute-common toxicity scale. Journal of the Peripheral Nervous System, 12(3), 210-215. doi: 10.1111/j.1529-8027.2007.00141.x
Cavaletti, G., Jann, S., Pace, A., Plasmati, R., Siciliano, G., Briani, C., . . . Giussani, G. (2006). Multi-center assessment of the total neuropathy score for chemotherapy-induced peripheral neurotoxicity. Journal of the Peripheral Nervous System, 11(2), 135-141. doi: 10.1111/j.1085-9489.2006.00078.x
Cella, D., Peterman, A., Hudgens, S., Webster, K., & Socinski, M. A. (2003). Measuring the side effects of taxane therapy in oncology: The functional assesment of cancer therapy-taxane (FACT-Taxane). Cancer, 98(4), 822-831. doi: 10.1002/cncr.11578
Cella, D., Yellen, S. B., Tulsky, D. S., Gray, G., Sarafian, B., Linn, E., . . . Brannon, J. (1993). The functional assessment of cancer therapy scale: Development and validation of the general measure. Journal of Clinical Oncology, 11(3), 570-579.
Chase, D. M., Huang, H., Foss, C. D., Wenzel, L. B., Monk, B. J., & Burger, R. A. (2015). Neurotoxicity in ovarian cancer patients on Gynecologic Oncology Group (GOG) protocol 218: Characteristics associated with toxicity and the effect of substitution with docetaxel: An NRG Oncology/Gynecologic Oncology Group study. Gynecologic Oncology, 136(2), 323-327. doi: 10.1016/j.ygyno.2014.12.021
Chaudhry, V., Rowinsky, E. K., Cornblath, D. R., & Donehower, R. C. (1993). Neurotoxicity of taxol. Journal of the National Cancer Institute, Monographs(15), 107-115.
Chaudhry, V., Rowinsky, E. K., Eisenhauer, E. A., Arbuck, S. G., & Donehower, R. C. (1993). Clinical toxicities encountered with paclitaxel (taxol). Seminars in Oncology, 20(4 Supp l 3), 1-15.
Chaudhry, V., Rowinsky, E. K., Sartorius, S. E., Donehower, R. C., & Cornblath, D. R. (1994). Peripheral neuropathy from taxol and cisplatin combination chemotherapy: Clinical and electrophysiological studies. Annals of Neurology, 35(3), 304-311. doi: 10.1002/ana.410350310
Conill, C., Verger, E., & Salamero, M. (1990). Performance status assessment in cancer patients. Cancer, 65(8), 1864-1866.
Cooley, M. E. (1998). Quality of life in persons with non-small cell lung cancer: A concept analysis. Cancer Nursing, 21(3), 151-161.
Cornblath, D. R., Chaudhry, V., Carter, K., Lee, D., Seysedadr, M., Miernicki, M., & Joh, T. (1999). Total neuropathy score: Validation and reliability study. Neurology, 53(8), 1660-1664.
Cui, Y., Shu, X. O., Gao, Y., Cai, H., Wen, W., Ruan, Z. X., . . . Zheng, W. (2004). The long-term impact of medical and socio-demographic factors on the quality of life of breast cancer survivors among Chinese women. Breast Cancer Research and Treatment, 87(2), 135-147. doi: 10.1023/b:brea.0000041620.76871.97
Davies, N. J., Kinman, G., Thomas, R. J., & Bailey, T. (2008). Information satisfaction in breast and prostate cancer patients: Implications for quality of life. Psycho-oncology, 17(10), 1048-1052.
Dodd, M. J., Cho, M. H., Cooper, B. A., & Miaskowski, C. (2010). The effect of symptom clusters on functional status and quality of life in women with breast cancer. European Journal of Oncology Nursing, 14(2), 101-110. doi: 10.1016/j.ejon.2009.09.005
Dodd, M. J., Miaskowski, C., & Paul, S. M. (2001). Symptom clusters and their effect on the functional status of patients with cancer. Oncology Nursing Forum, 28(3), 465-470.
Doroshow, J. H. (2011). Topoisomerase II inhibitors: Anthracyclines. In Chabner, B. A. & Longo, D. L. (Eds.), Cancer chemotherapy and biotherapy: Principles and practice (5th ed., pp. 356-382). Philadelphia, PA: Lippincott Williams & Wilkins Health
Eckhoff, L., Knoop, A. S., Jensen, M. B., & Ewertz, M. (2015). Persistence of docetaxel-induced neuropathy and impact on quality of life among breast cancer survivors. European Journal of Cancer, 51(3), 292-300. doi: 10.1016/j.ejca.2014.11.024
Eckhoff, L., Knoop, A. S., Jensen, M. B., Ejlertsen, B., & Ewertz, M. (2013). Risk of docetaxel-induced peripheral neuropathy among 1,725 Danish patients with early stage breast cancer. Breast Cancer Research and Treatment, 142(1), 109-118. doi: 10.1007/s10549-013-2728-2
Engel, J., Kerr, J., Schlesinger-raab, A., Eckel, R., Sauer, H., & Hölzel, D. (2003). Predictors of Quality of Life of Breast Cancer Patients. Acta Oncologica, 42(7), 710-718. doi: 10.1080/02841860310017658
Faul, F., Erdfelder, E., Buchner, A., & Lang, A. G. (2009). Statistical power analyses using G*Power 3.1: Tests for correlation and regression analyses. Behavior Research Methods, 41(4), 1149-1160. doi: 10.3758/brm.41.4.1149
Fayers, P. M., & Machin, D. (2000). Quality of life: Assessment, analysis, and interpretation. New York, NK: John Wiley.
Ferlay, J., Soerjomataram, I., Dikshit, R., Eser, S., Mathers, C., Rebelo, M., . . . Bray, F. (2015). Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012. International Journal of Cancer, 136(5), E359-E386. doi: 10.1002/ijc.29210
Ferrans, C. E., & Powers, M. J. (1985). Quality of life index: Development and psychometric properties. Advances in Nursing Science, 8(1), 15-24.
Forsyth, P. A., Balmaceda, C., Peterson, K., Seidman, A. D., Brasher, P., & DeAngelis, L. M. (1997). Prospective study of paclitaxel-induced peripheral neuropathy with quantitative sensory testing. Journal of Neuro-oncology, 35(1), 47-53.
Functional Assessment of Chronic Illness Therapy.org. (2010). Questionnaires: FACT-B: For patients with Breast cancer. Retrieved July 16, 2015 from http//www.facit.org/FACITOrg/Questionnaires
Garcia, S. F., & Hahn, E. A. (2012). Measure validation is an ongoing process: The Functional Assessment of Cancer Therapy-Breast Symptom Index as a case example. Annals of Palliative Medicine, 1(3), 207-210. doi: 10.3978/j.issn.2224-5820.2012.10.07
Gewandter, J. S., Fan, L., Magnuson, A., Mustian, K., Peppone, L., Heckler, C., . . . Mohile, S. G. (2013). Falls and functional impairments in cancer survivors with chemotherapy-induced peripheral neuropathy (CIPN): A University of Rochester CCOP study. Support Care Cancer, 21(7), 2059-2066. doi: 10.1007/s00520-013-1766-y
Gogas, H., Shapiro, F., Aghajanian, C., Fennelly, D., Almadrones, L., Hoskins, W. J., & Spriggs, D. R. (1996). The impact of diabetes mellitus on the toxicity of therapy for advanced ovarian cancer. Gynecologic oncology, 61(1), 22-26. doi: 10.1006/gyno.1996.0090
Hahn, E. A., Holzner, B., Kemmler, G., Sperner-Unterweger, B., Hudgens, S. A., & Cella, D. (2005). Cross-cultural evaluation of health status using item response theory: FACT-B comparisons between Austrian and U.S. patients with breast cancer. Eval Health Prof, 28(2), 233-259. doi: 10.1177/0163278705275343
Hartl, K., Janni, W., Kastner, R., Sommer, H., Strobl, B., Rack, B., & Stauber, M. (2003). Impact of medical and demographic factors on long-term quality of life and body image of breast cancer patients. Annals of Oncology, 14(7), 1064-1071.
Hausheer, F. H., Schilsky, R. L., Bain, S., Berghorn, E. J., & Lieberman, F. (2006). Diagnosis, management, and evaluation of chemotherapy-induced peripheral neuropathy. Seminars in Oncology, 33(1), 15-49. doi: 10.1053/j.seminoncol.2005.12.010
Hershman, D. L., Weimer, L. H., Wang, A., Kranwinkel, G., Brafman, L., Fuentes, D., . . . Crew, K. D. (2011). Association between patient reported outcomes and quantitative sensory tests for measuring long-term neurotoxicity in breast cancer survivors treated with adjuvant paclitaxel chemotherapy. Breast Cancer Research and Treatment, 125(3), 767-774. doi: 10.1007/s10549-010-1278-0
Hertz, D. L., Roy, S., Jack, J., Motsinger-Reif, A. A., Drobish, A., Clark, L. S., . . . McLeod, H. L. (2014). Genetic heterogeneity beyond CYP2C8*3 does not explain differential sensitivity to paclitaxel-induced neuropathy. Breast cancer research and treatment, 145(1), 245-254. doi: 10.1007/s10549-014-2910-1
Hornquist, J. O. (1982). The concept of quality of life. Scandinavian Journal of Social Medicine, 10(2), 57-61.
Huang, H. Q., Brady, M. F., Cella, D., & Fleming, G. (2007). Validation and reduction of FACT/GOG-Ntx subscale for platinum/paclitaxel-induced neurologic symptoms: A gynecologic oncology group study. International Journal of Gynecological Cancer, 17(2), 387-393. doi: 10.1111/j.1525-1438.2007.00794.x
Hurria, A., Hurria, A., Zuckerman, E., Panageas, K. S., Fornier, M., D'Andrea, G., . . . Hudis, C. (2006). A prospective, longitudinal study of the functional status and quality of life of older patients with breast cancer receiving adjuvant chemotherapy. Journal of the American Geriatrics Society, 54(7), 1119-1124. doi: 10.1111/j.1532-5415.2006.00789.x
Jeffe, D. B., Perez, M., Cole, E. F., Liu, Y., & Schootman, M. (2016). The effects of surgery type and chemotherapy on early-stage breast cancer patients' quality of life over 2-year follow-up. Annals of Surgical Oncology, 23(3), 735-743. doi: 10.1245/s10434-015-4926-0
Jones, S. E., Erban, J., Overmoyer, B., Budd, G. T., Hutchins, L., Lower, E., . . . Ravdin, P. M. (2005). Randomized phase III study of docetaxel compared with paclitaxel in metastatic breast cancer. Journal of Clinical Oncology, 23(24), 5542-5551. doi: 10.1200/jco.2005.02.027
Karnofsky, D. A., Abelmann, W. H., Craver, L. F., & Burchenal, J. H. (1948). The use of the nitrogen mustards in the palliative treatment of carcinoma. With particular reference to bronchogenic carcinoma. Cancer, 1(4), 634-656.
Kudlowitz, D., & Muggia, F. (2013). Defining risks of taxane neuropathy: Insights from randomized clinical trials. Clinical Cancer Research, 19(17), 4570-4577. doi: 10.1158/1078-0432.ccr-13-0572
Kuroi, K., & Shimozuma, K. (2004). Neurotoxicity of taxanes: Symptoms and quality of life assessment. Breast Cancer, 11(1), 92-99.
Kuroi, K., Shimozuma, K., Ohashi, Y., Hisamatsu, K., Masuda, N., Takeuchi, A., . . . Hausheer, F. H. (2009). Prospective assessment of chemotherapy-induced peripheral neuropathy due to weekly paclitaxel in patients with advanced or metastatic breast cancer (CSP-HOR 02 study). Support Care Cancer, 17(8), 1071-1080. doi: 10.1007/s00520-008-0550-x
Kuroi, K., Shimozuma, K., Ohashi, Y., Takeuchi, A., Aranishi, T., Morita, S., . . . Hausheer, F. H. (2008). A questionnaire survey of physicians’ perspectives regarding the assessment of chemotherapy-induced peripheral neuropathy in patients with breast cancer. Japanese Journal of Clinical Oncology, 38(11), 748-754. doi: 10.1093/jjco/hyn100
Kwan, M. L., Ergas, I. J., Somkin, C. P., Quesenberry, C. P., Jr., Neugut, A. I., Hershman, D. L., . . . Kushi, L. H. (2010). Quality of life among women recently diagnosed with invasive breast cancer: The Pathways Study. Breast Cancer Research and Treatment, 123(2), 507-524. doi: 10.1007/s10549-010-0764-8
Lee, C. F., Luo, N., Ng, R., Wong, N., Yap, Y., Lo, S., . . . Cheung, Y. (2013). Comparison of the measurement properties between a short and generic instrument, the 5-level EuroQoL Group’s 5-dimension (EQ-5D-5L) questionnaire, and a longer and disease-specific instrument, the Functional Assessment of Cancer Therapy—Breast (FACT-B), in Asian breast cancer patients. Quality of life research, 22(7), 1745-1751. doi: 10.1007/s11136-012-0291-7
Lee, J. J., & Swain, S. M. (2006). Peripheral neuropathy induced by microtubule-stabilizing agents. Journal of Clinical Oncology, 24(10), 1633-1642. doi: 10.1200/jco.2005.04.0543
Leidy, N. K. (1994a). Functional status and the forward progress of merry-go-rounds: Toward a coherent analytical framework. Nursing research, 43(4), 196-202.
Leidy, N. K. (1994b). Using functional status to assess treatment outcomes. Chest Journal, 106(6), 1645-1646.
Loprinzi, C. L., Reeves, B. N., Dakhil, S. R., Sloan, J. A., Wolf, S. L., Burger, K. N., . . . Lachance, D. H. (2011). Natural history of paclitaxel-associated acute pain syndrome: Prospective cohort study NCCTG N08C1. Journal of Clinical Oncology, 29(11), 1472-1478. doi: 10.1200/jco.2010.33.0308
Lotti, M., Becker, C. E., & Aminoff, M. J. (1982). Occupational Peripheral Neuropathies. Western Journal of Medicine, 137(6), 493-498.
Lu, Q., You, J., Kavanagh, A., Warmoth, K., Meng, Z., Chen, Z., . . . Cohen, L. (2016). Differences in quality of life between American and Chinese breast cancer survivors. Support Care in Cancer. doi: 10.1007/s00520-016-3195-1
Mandzuk, L. L., & McMillan, D. E. (2005). A concept analysis of quality of life. Journal of Orthopaedic Nursing, 9(1), 12-18. doi: 10.1016/j.joon.2004.11.001
Meeberg, G. A. (1993). Quality of life: A concept analysis. Journal of Advanced Nursing, 18(1), 32-38. doi: 10.1046/j.1365-2648.1993.18010032.x
Mielke, S., Mross, K., Gerds, T. A., Schmidt, A., Wasch, R., Berger, D. P., . . . Behringer, D. (2003). Comparative neurotoxicity of weekly non-break paclitaxel infusions over 1 versus 3 h. Anticancer Drugs, 14(10), 785-792. doi: 10.1097/01.cad.0000097709.69687.fb
Moberg, E. (1990). Two-point discrimination test. A valuable part of hand surgical rehabilitation, e.g. in tetraplegia. Scandinavian Journal of Rehabilitation Medicine, 22(3), 127-134.
Mols, F., Beijers, T., Vreugdenhil, G., & van de Poll-Franse, L. (2014). Chemotherapy-induced peripheral neuropathy and its association with quality of life: A systematic review. Support Care Cancer, 22(8), 2261-2269. doi: 10.1007/s00520-014-2255-7
Mols, F., Thong, M. S., Vreugdenhil, G., & van de Poll‐Franse, L. V. (2009). Long‐term cancer survivors experience work changes after diagnosis: Results of a population‐based study. Psycho‐Oncology, 18(12), 1252-1260. doi: 10.1002/pon.1522
Moro-Valdezate, D., Buch-Villa, E., Peiró, S., Morales-Monsalve, M. D., Caballero-Gárate, A., Martínez-Agulló, Á., . . . Ortega-Serrano, J. (2014). Factors associated with health-related quality of life in a cohort of Spanish breast cancer patients. Breast Cancer, 21(4), 442-452. doi: 10.1007/s12282-012-0402-x
Moulder, S. L., Holmes, F. A., Tolcher, A. W., Thall, P., Broglio, K., Valero, V., . . . Hortobagyi, G. N. (2010). A randomized phase 2 trial comparing 3-hour versus 96-hour infusion schedules of paclitaxel for the treatment of metastatic breast cancer. Cancer, 116(4), 814-821. doi: 10.1002/cncr.24870
Nabholtz, J. M., Gelmon, K., Bontenbal, M., Spielmann, M., Catimel, G., Conte, P., . . . Winograd, B. (1996). Multicenter, randomized comparative study of two doses of paclitaxel in patients with metastatic breast cancer. Journal of Clinical Oncology, 14(6), 1858-1867.
National Cancer Institute. (2010). Common terminology criteria for adverse events (CTCAE): Version 4.0. Retrieved June 10, 2015 from http://evs.nci.nih.gov/ftp1/CTCAE/CTCAE_4.03_2010-06-14_QuickReference_8.5x11.pdf
National Committee on Vital & Health Statistics. (2001, July). Clarifying and reporting functional status. Retrieved April 5, 2015 from http://www. ncvhs.hhs.gov/010617rp.pdf
National Comprehensive Cancer Network. (2014). NCCN guidelines for patients®: Stages I and II breast cancer (version 1). Retrieved April 6, 2015 from http://www.nccn.org/patients/guidelines/stage_i_ii_breast/files/assets/common/downloads/files/stage_I_II_breast.pdf
National Comprehensive Cancer Network. (2015). NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®): Breast cancer (version 3). Retrieved August 20, 2015 from http://www.nccn.org/professionals/physician_gls/f_guidelines.asp
National Institutes of Health (2015, July 24). Breast Cancer: For health professionals (PDQ®). Retrieved August 20, 2015 from http://www.cancer.gov/types/breast/hp/breast-treatment-pdq
Neuner, J. M., Zokoe, N., McGinley, E. L., Pezzin, L. E., Yen, T. W. F., Schapira, M. M., & Nattinger, A. B. (2014). Quality of life among a population-based cohort of older patients with breast cancer. The Breast, 23(5), 609-616. doi: 10.1016/j.breast.2014.06.002
Ng, R., Lee, C. F., Wong, N. S., Luo, N., Yap, Y. S., Lo, S. K., . . . Cheung, Y. B. (2012). Measurement properties of the English and Chinese versions of the Functional Assessment of Cancer Therapy-Breast (FACT-B) in Asian breast cancer patients. Breast Cancer Research and Treatment, 131(2), 619-625. doi: 10.1007/s10549-011-1764-z
Ohsumi, S., Shimozuma, K., Morita, S., Hara, F., Takabatake, D., Takashima, S., . . . Takashima, S. (2009). Factors associated with health-related quality-of-life in breast cancer survivors: Influence of the type of surgery. Japanese Journal of Clinical Oncology, 39(8), 491-496. doi: 10.1093/jjco/hyp060
O'Shaughnessy, J., Miles, D., Vukelja, S., Moiseyenko, V., Ayoub, J. P., Cervantes, G., . . . Leonard, R. (2002). Superior survival with capecitabine plus docetaxel combination therapy in anthracycline-pretreated patients with advanced breast cancer: Phase III trial results. Journal of Clinical Oncology, 20(12), 2812-2823.
Osmani, K., Vignes, S., Aissi, M., Wade, F., Milani, P., Levy, B. I., & Kubis, N. (2012). Taxane-induced peripheral neuropathy has good long-term prognosis: A 1- to 13-year evaluation. Journal of Neurology, 259(9), 1936-1943. doi: 10.1007/s00415-012-6442-5
Ostchega, Y., Donohue, M., & Fox, N. (1988). High-dose cisplatin-related peripheral neuropathy. Cancer Nursing, 11(1), 23-32.
Pace, A., Nistico, C., Cuppone, F., Bria, E., Galie, E., Graziano, G., . . . Terzoli, E. (2007). Peripheral neurotoxicity of weekly paclitaxel chemotherapy: A schedule or a dose issue? Clinical Breast Cancer, 7(7), 550-554. doi: 10.3816/CBC.2007.n.010
Pachman, D. R., Barton, D. L., Swetz, K. M., & Loprinzi, C. L. (2012). Troublesome symptoms in cancer survivors: Fatigue, insomnia, neuropathy, and pain. Journal of Clinical Oncology, 30(30), 3687-3696. doi: 10.1200/JCO.2012.41.7238
Pachman, D. R., Watson, J. C., Lustberg, M. B., Wagner-Johnston, N. D., Chan, A., Broadfield, L., . . . Loprinzi, C. L. (2014). Management options for established chemotherapy-induced peripheral neuropathy. Supportive Care in Cancer, 22(8), 2281-2295. doi: 10.1007/s00520-014-2289-x
Padilla, G. V., Presant, C., Grant, M. M., Metter, G., Lipsett, J., & Heide, F. (1983). Quality of life index for patients with cancer. Research in Nursing & Health, 6(3), 117-126.
Paisley, A. N., Abbott, C. A., Van Schie, C. H. M., & Boulton, A. J. M. (2002). A comparison of the Neuropen against standard quantitative sensory-threshold measures for assessing peripheral nerve function. Diabetic Medicine, 19(5), 400-405. doi: 10.1046/j.1464-5491.2002.00706.x
Park, S. B., Goldstein, D., Krishnan, A. V., Lin, C. S., Friedlander, M. L., Cassidy, J., . . . Kiernan, M. C. (2013). Chemotherapy-induced peripheral neurotoxicity: A critical analysis. A Cancer Journal for Clinicians, 63(6), 419-437. doi: 10.3322/caac.21204
Pereira, S., Fontes, F., Sonin, T., Dias, T., Fragoso, M., Castro-Lopes, J. M., & Lunet, N. (2016). Chemotherapy-induced peripheral neuropathy after neoadjuvant or adjuvant treatment of breast cancer: A prospective cohort study. Support Care Cancer, 24(4), 1571-1581. doi: 10.1007/s00520-015-2935-y
Peto, R., Davies, C., Godwin, J., Gray, R., Pan, H. C., Clarke, M., . . . Pritchard, K. (2012). Comparisons between different polychemotherapy regimens for early breast cancer: Meta-analyses of long-term outcome among 100,000 women in 123 randomised trials. Lancet, 379(9814), 432-444. doi: 10.1016/s0140-6736(11)61625-5
Pike, C. T., Birnbaum, H. G., Muehlenbein, C. E., Pohl, G. M., & Natale, R. B. (2012). Healthcare costs and workloss burden of patients with chemotherapy-associated peripheral neuropathy in breast, ovarian, head and neck, and nonsmall cell lung cancer. Chemotherapy Research and Practice, 2012, 1-10. doi: 10.1155/2012/913848
Pinquart, M., Koch, A., Eberhardt, B., Brix, C., Wedding, U., & Rohrig, B. (2006). Associations of functional status and depressive symptoms with health-related quality of life in cancer patients. Quality of life research, 15(10), 1565-1570. doi: 10.1007/s11136-006-0016-x
Polit, D. F., & Beck, C. T. (2012). Nursing research: Generating and assessing evidence for nursing practice. (9th ed.). Philadelphia, PA: Lippincott Williams & Wilkins.
Polomano, R. C., & Farrar, J. T. (2006). Pain and neuropathy in cancer survivors. Cancer Nursing, 29(2S), 39-47.
Poradzisz, M., & Florczak, K. L. (2013). Quality of life: Input or outcome? Nursing Science Quarterly, 26(2), 116-120. doi: 10.1177/0894318413477149
Postma, T. J., & Heimans, J. J. (2000). Grading of chemotherapy-induced peripheral neuropathy. Annals of Oncology, 11(5), 509-513.
Postma, T. J., Aaronson, N. K., Heimans, J. J., Muller, M. J., Hildebrand, J. G., Delattre, J. Y., . . . Lucey, R. (2005). The development of an EORTC quality of life questionnaire to assess chemotherapy-induced peripheral neuropathy: The QLQ-CIPN20. European Journal of Cancer, 41(8), 1135-1139. doi: 10.1016/j.ejca.2005.02.012
Postma, T. J., Heimans, J. J., Muller, M. J., Ossenkoppele, G. J., Vermorken, J. B., & Aaronson, N. K. (1998). Pitfalls in grading severity of chemotherapy-induced peripheral neuropathy. Annals of oncology, 9(7), 739-744.
Rowinsky, E. K. (2011). Antimitotic drugs. In Chabner, B. A. & Longo, D. L. (Eds.), Cancer chemotherapy and biotherapy: Principles and practice (5th ed., pp. 216-266). Philadelphia, PA: Lippincott Williams & Wilkins Health.

 Saad, M., Psimaras, D., Tafani, C., Sallansonnet-Froment, M., Calvet, J. H., Vilier, A., . . . Ricard, D. (2016). Quick, non-invasive and quantitative assessment of small fiber neuropathy in patients receiving chemotherapy. Journal of Neuro-oncology, 127(2), 373-380. doi: 10.1007/s11060-015-2049-x
Safaee, A., Moghimi-Dehkordi, B., Zeighami, B., Tabatabaee, H., & Pourhoseingholi, M. (2008). Predictors of quality of life in breast cancer patients under chemotherapy. Indian Journal Of Cancer, 45(3), 107-111.
Sasane, M., Tencer, T., French, A., Maro, T., & Beusterien, K. M. (2010). Patient-reported outcomes in chemotherapy-induced peripheral neuropathy: A review. The Journal of Supportive Oncology, 8(6), 15-21.
Schag, C. C., Heinrich, R. L., & Ganz, P. A. (1984). Karnofsky performance status revisited: Reliability, validity, and guidelines. Journal of Clinical Oncology, 2(3), 187-193.
Schneider, B. P., Li, L., Miller, K., Flockhart, D., Radovich, M., Hancock, B. A., . . . Sledge, G. W. (2011). Genetic associations with taxane-induced neuropathy by a genome-wide association study (GWAS) in E5103 [abstract]. Journal of Clinical Oncology, 29(15), 1000.
Schneider, B. P., Zhao, F., Wang, M., Stearns, V., Martino, S., Jones, V., . . . Sparano, J. A. (2012). Neuropathy is not associated with clinical outcomes in patients receiving adjuvant taxane-containing therapy for operable breast cancer. Journal of Clinical Oncology, 30(25), 3051-3057. doi: 10.1200/jco.2011.39.8446
Schwartz, C. E., & Sprangers, M. A. (2002). An introduction to quality of life assessment in oncology: The value of measuring patient-reported outcomes. The American Journal of Managed Care, 8(Suppl 18), S550-S559.
Seidman, A. D., Berry, D., Cirrincione, C., Harris, L., Muss, H., Marcom, P. K., . . . Hudis, C. (2008). Randomized phase III trial of weekly compared with every-3-weeks paclitaxel for metastatic breast cancer, with trastuzumab for all HER-2 overexpressors and random assignment to trastuzumab or not in HER-2 nonoverexpressors: Final results of Cancer and Leukemia Group B protocol 9840. Journal of Clinical Oncology, 26(10), 1642-1649. doi: 10.1200/jco.2007.11.6699
Semb, K. A., Aamdal, S., & Oian, P. (1998). Capillary protein leak syndrome appears to explain fluid retention in cancer patients who receive docetaxel treatment. Journal of Clinical Oncology, 16(10), 3426-3432.
Shimozuma, K., Ohashi, Y., Takeuchi, A., Aranishi, T., Morita, S., Kuroi, K., . . . Hausheer, F. H. (2012). Taxane-induced peripheral neuropathy and health-related quality of life in postoperative breast cancer patients undergoing adjuvant chemotherapy: N-SAS BC 02, a randomized clinical trial. Support Care Cancer, 20(12), 3355-3364. doi: 10.1007/s00520-012-1492-x
Shimozuma, K., Ohashi, Y., Takeuchi, A., Aranishi, T., Morita, S., Kuroi, K., . . . Hausheer, F. H. (2009). Feasibility and validity of the patient neurotoxicity questionnaire during taxane chemotherapy in a phase III randomized trial in patients with breast cancer: N-SAS BC 02. Support Care Cancer, 17(12), 1483-1491. doi: 10.1007/s00520-009-0613-7
Shiroiwa, T., Fukuda, T., Shimozuma, K., Kuranami, M., Suemasu, K., Ohashi, Y., & Watanabe, T. (2011). Comparison of EQ-5D scores among anthracycline-containing regimens followed by taxane and taxane-only regimens for node-positive breast cancer patients after surgery: The N-SAS BC 02 trial. Value in Health, 14(5), 746-751. doi: 10.1016/j.jval.2011.01.007
Siefert, M. L. (2010). Fatigue, pain, and functional status during outpatient chemotherapy. Oncology Nursing Forum, 37(2), E114-E123. doi: 10.1188/10.ONF.114-123
Siegel, R., Ma, J., Zou, Z., & Jemal, A. (2014). Cancer statistics, 2014. A Cancer Journal for Clinicians, 64(1), 9-29. doi: 10.3322/caac.21208
Sio, T. T., Chang, K., Jayakrishnan, R., Wu, D., Politi, M., Malacarne, D., . . . Chung, M. (2014). Patient age is related to decision-making, treatment selection, and perceived quality of life in breast cancer survivors. World Journal of Surgical Oncology, 12, 230. doi: 10.1186/1477-7819-12-230
Sissung, T. M., Mross, K., Steinberg, S. M., Behringer, D., Figg, W. D., Sparreboom, A., & Mielke, S. (2006). Association of ABCB1 genotypes with paclitaxel-mediated peripheral neuropathy and neutropenia. European Journal of Cancer, 42(17), 2893-2896. doi: 10.1016/j.ejca.2006.06.017
Smith, E. M. (2013). Current methods for the assessment and management of taxane-related neuropathy. Clinical Journal of Oncology Nursing, 17, 22-34. doi: 10.1188/13.CJON.S1.22-34
Smith, E. M., Beck, S. L., & Cohen, J. (2008). The total neuropathy score: A tool for measuring chemotherapy-induced peripheral neuropathy. Oncology Nursing Forum, 35(1), 96-102.
Smith, E. M., Campbell, G., Tofthagen, C., Kottschade, L., Collins, M. L., Warton, C., . . . Visovsky, C. (2014). Nursing knowledge, practice patterns, and learning preferences regarding chemotherapy-induced peripheral neuropathy. Oncology Nursing Forum, 41(6), 669-679. doi: 10.1188/14.onf.669-679
Smith, E. M., Cohen, J. A., Pett, M. A., & Beck, S. L. (2010). The reliability and validity of a modified total neuropathy score-reduced and neuropathic pain severity items when used to measure chemotherapy-induced peripheral neuropathy in patients receiving taxanes and platinums. Cancer Nursing, 33(3), 173-183. doi: 10.1097/NCC.0b013e3181c989a3
Smith, R. E., Brown, A. M., Mamounas, E. P., Anderson, S. J., Lembersky, B. C., Atkins, J. H., . . . Thirlwell, M. P. (1999). Randomized trial of 3-hour versus 24-hour infusion of high-dose paclitaxel in patients with metastatic or locally advanced breast cancer: National Surgical Adjuvant Breast and Bowel Project Protocol B-26. Journal of Clinical Oncology, 17(11), 3403-3411.
Soundararajan, N., & Russell, I. (2007). A randomised comparison of a hand-held Neurotip and the Neuropen for assessing loss of touch sensation during spinal anaesthesia for caesarean section. International journal of obstetric anesthesia, 16(3), 202-207. doi: 10.1016/j.ijoa.2006.11.008
Sparano, J. A., Wang, M., Martino, S., Jones, V., Perez, E. A., Saphner, T., . . . Davidson, N. E. (2008). Weekly Paclitaxel in the Adjuvant Treatment of Breast Cancer. New England Journal of Medicine, 358(16), 1663-1671. doi: doi:10.1056/NEJMoa0707056
Speck, R. M., DeMichele, A., Farrar, J. T., Hennessy, S., Mao, J. J., Stineman, M. G., & Barg, F. K. (2012). Scope of symptoms and self-management strategies for chemotherapy-induced peripheral neuropathy in breast cancer patients. Support Care Cancer, 20(10), 2433-2439. doi: 10.1007/s00520-011-1365-8
Speck, R. M., Sammel, M. D., Farrar, J. T., Hennessy, S., Mao, J. J., Stineman, M. G., & DeMichele, A. (2013). Impact of chemotherapy-induced peripheral neuropathy on treatment delivery in nonmetastatic breast cancer. Journal of Oncology Practice, 9(5), 234-240. doi: 10.1200/jop.2012.000863
Stubblefield, M. D., Burstein, H. J., Burton, A. W., Custodio, C. M., Deng, G. E., Ho, M., . . . Tummala, S. (2009). NCCN task force report: Management of neuropathy in cancer. Journal of the National Comprehensive Cancer Network, 7(Suppl 5), 1-26.
Tabernero, J., Climent, M. A., Lluch, A., Albanell, J., Vermorken, J. B., Barnadas, A., . . . Baselga, J. (2004). A multicentre, randomised phase II study of weekly or 3-weekly docetaxel in patients with metastatic breast cancer. Annals of Oncology, 15(9), 1358-1365. doi: 10.1093/annonc/mdh349
Taira, N., Shimozuma, K., Shiroiwa, T., Ohsumi, S., Kuroi, K., Saji, S., . . . Katsumata, N. (2011). Associations among baseline variables, treatment-related factors and health-related quality of life 2 years after breast cancer surgery. Breast Cancer Research and Treatment, 128(3), 735-747. doi: 10.1007/s10549-011-1631-y
Tam, S. L., Archibald, V., Jassar, B., Tyreman, N., & Gordon, T. (2001). Increased neuromuscular activity reduces sprouting in partially denervated muscles. The Journal of Neuroscience, 21(2), 654-667.
Tanabe, Y., Hashimoto, K., Shimizu, C., Hirakawa, A., Harano, K., Yunokawa, M., . . . Fujiwara, Y. (2013). Paclitaxel-induced peripheral neuropathy in patients receiving adjuvant chemotherapy for breast cancer. International Journal of Clinical Oncology, 18(1), 132-138. doi: 10.1007/s10147-011-0352-x
Taylor, R. M., Gibson, F., & Franck, L. S. (2008). A concept analysis of health-related quality of life in young people with chronic illness. Journal of Clinical Nursing, 17(14), 1823-1833. doi: 10.1111/j.1365-2702.2008.02379.x
The WHOQOL Group. (1995). The World Health Organization quality of life assessment (WHOQOL): Position paper from the World Health Organization. Social Science & Medicine, 41(10), 1403-1409. doi: 10.1016/0277-9536(95)00112-K
Theiss, C., & Meller, K. (2000). Taxol impairs anterograde axonal transport of microinjected horseradish peroxidase in dorsal root ganglia neurons in vitro. Cell and Tissue Research, 299(2), 213-224.
Timperi, A. W., Ergas, I. J., Rehkopf, D. H., Roh, J. M., Kwan, M. L., & Kushi, L. H. (2013). Employment status and quality of life in recently diagnosed breast cancer survivors. Psychooncology, 22(6), 1411-1420. doi: 10.1002/pon.3157
Tofthagen, C. (2010). Patient perceptions associated with chemotherapy-induced peripheral neuropathy. Clinical Journal of Oncology Nursing, 14(3), E22-E28. doi: 10.1188/10.CJON.E22-E28
Tofthagen, C., Overcash, J., & Kip, K. (2012). Falls in persons with chemotherapy-induced peripheral neuropathy. Supportive Care in Cancer, 20(3), 583-589. doi: 10.1007/s00520-011-1127-7
Tofthagen, C., Visovsky, C. M., & Hopgood, R. (2013). Chemotherapy-induced peripheral neuropathy. Clinical Journal of Oncology Nursing, 17(2), 138-144. doi: 10.1188/13.CJON.138-144
Torres, S., Trudeau, M., Eisen, A., Earle, C. C., & Chan, K. K. (2015). Adjuvant taxane-based chemotherapy for early stage breast cancer: A real-world comparison of chemotherapy regimens in Ontario. Breast Cancer Research and Treatment, 152(1). 137-145. doi: 10.1007/s10549-015-3441-0
Trotti, A., Colevas, A. D., Setser, A., Rusch, V., Jaques, D., Budach, V., . . . Rubin, P. (2003). CTCAE v3.0: Development of a comprehensive grading system for the adverse effects of cancer treatment. Seminars in Radiation Oncology, 13(3), 176-181. doi: 10.1016/s1053-4296(03)00031-6
Van Cleave, J. H., Egleston, B. L., & McCorkle, R. (2011). Factors affecting recovery of functional status in older adults after cancer surgery. Journal of the American Geriatrics Society, 59(1), 34-43. doi: 10.1111/j.1532-5415.2010.03210.x
van Nes, S. I., Faber, C. G., Hamers, R. M., Harschnitz, O., Bakkers, M., Hermans, M. C., . . . Merkies, I. S. (2008). Revising two-point discrimination assessment in normal aging and in patients with polyneuropathies. Journal of Neurology, Neurosurgery, and Psychiatry, 79(7), 832-834. doi: 10.1136/jnnp.2007.139220
Vatandoust, S., Joshi, R., Pittman, K. B., Esterman, A., Broadbridge, V., Adams, J., . . . Price, T. J. (2014). A descriptive study of persistent oxaliplatin-induced peripheral neuropathy in patients with colorectal cancer. Support Care Cancer, 22(2), 513-518. doi: 10.1007/s00520-013-2004-3
Verstappen, C. C. P., Heimans, J. J., Hoekman, K., & Postma, T. J. (2003). Neurotoxic complications of chemotherapy in patients with cancer: Clinical signs and optimal management. Drugs, 63(15), 1549-1563.
Visovsky, C., & Daly, B. J. (2004). Clinical evaluation and patterns of chemotherapy-induced peripheral neuropathy. Journal of the American Academy of Nurse Practitioners,16(8), 353-359. doi: 10.1111/j.1745-7599.2004.tb00458.x
Visovsky, C., Meyer, R. R., Roller, J., & Poppas, M. (2008). Evaluation and management of peripheral neuropathy in diabetic patients with cancer. Clinical Journal of Oncology Nursing, 12(2), 243-247. doi: 10.1188/08.CJON.243-247
Wampler, M. A., Miaskowski, C., Hamel, K., Byl, N., Rugo, H., & Topp, K. S. (2006). The modified total neuropathy score: A clinically feasible and valid measure of taxane-induced peripheral neuropathy in women with breast cancer. The Journal of Community and Supportive Oncology, 4(8), W9-W16.
Wang, Y. J., Boehmke, M., Wu, Y. W., Dickerson, S. S., & Fisher, N. (2011). Effects of a 6-week walking program on Taiwanese women newly diagnosed with early-stage breast cancer. Cancer Nursing, 34(2), E1-E13. doi: 10.1097/NCC.0b013e3181e4588d
Webster, K., Cella, D., & Yost, K. (2003). The Functional Assessment of Chronic Illness Therapy (FACIT) measurement system: Properties, applications, and interpretation. Health Qual Life Outcomes, 1, 79. doi: 10.1186/1477-7525-1-79. Retrieved from http://www.hqlo.com/content/1/1/79
White, C. M., Pritchard, J., & Turner-Stokes, L. (2011). Exercise for people with peripheral neuropathy. Cochrane Database of Systematic Reviews, (4). doi: 10.1002/14651858.CD003904.pub2.
Wickham, R. (2007). Chemotherapy-induced peripheral neuropathy: A review and implications for oncology nursing practice. Clinical Journal of Oncology Nursing, 11(3), 361-376. doi: 10.1188/07.CJON.361-376
Williams, R. E., Levine, K. B., Kalilani, L., Lewis, J., & Clark, R. V. (2009). Menopause-specific questionnaire assessment in US population-based study shows negative impact on health-related quality of life. Maturitas, 62(2), 153-159. doi: 10.1016/j.maturitas.2008.12.006
Windebank, A. J., & Grisold, W. (2008). Chemotherapy-induced neuropathy. Journal of the Peripheral Nervous System, 13(1), 27-46. doi: 10.1111/j.1529-8027.2008.00156.x
Winer, E. P., Berry, D. A., Woolf, S., Duggan, D., Kornblith, A., Harris, L. N., . . . Norton, L. (2004). Failure of higher-dose paclitaxel to improve outcome in patients with metastatic breast cancer: Cancer and leukemia group B trial 9342. Journal of Clinical Oncology, 22(11), 2061-2068. doi: 10.1200/jco.2004.08.048
Wolf, S. L., Qin, R., Barton, D. L., Sloan, J. A., Liu, H., Aaronson, N. K., . . . Loprinzi, C. L. (2009). Relationship of sensory symptoms and motor function in patients with chemotherapy-induced peripheral neuropathy (CIPN) utilizing the EORTC QLQ CIPN20: NCCTG study N06CA [abstract]. Journal of Clinical Oncology, 27(Suppl 15), 9587.
Wolfe, G. I., & Trivedi, J. R. (2004). Painful peripheral neuropathy and its nonsurgical treatment. Muscle & Nerve, 30(1), 3-19. doi: 10.1002/mus.20057
Would Health Organization. (1993). Study protocol for the World Health Organization project to develop a quality of life assessment instrument (WHOQOL). Quality of Life Research, 2(2), 153-159.
Would Health Organization. (2015). Breast cancer: Estimated incidence, mortality and prevalence worldwide in 2012. Retrieved May 8, 2015 from http://globocan.iarc.fr/Pages/fact_sheets_cancer.aspx?cancer=breast#
Yao, G., Chung, C. W., Yu, C. F., & Wang, J. D. (2002). Development and verification of validity and reliability of the WHOQOL-BREF Taiwan version. Journal of the Formosan Medical Association, 101(5), 342-351.
Yates, J. W., Chalmer, B., & McKegney, F. P. (1980). Evaluation of patients with advanced cancer using the Karnofsky performance status. Cancer, 45(8), 2220-2224.
Yost, K. J., & Eton, D. T. (2005). Combining distribution- and anchor-based approaches to determine minimally important differences: The FACIT experience. Evaluation & The Health Professions, 28(2), 172-191. doi: 10.1177/0163278705275340
Zhan, L. (1992). Quality of life: Conceptual and measurement issues. Journal of Advanced Nursing, 17(7), 795-800. doi: 10.1111/j.1365-2648.1992.tb02000.x


連結至畢業學校之論文網頁點我開啟連結
註: 此連結為研究生畢業學校所提供,不一定有電子全文可供下載,若連結有誤,請點選上方之〝勘誤回報〞功能,我們會盡快修正,謝謝!
QRCODE
 
 
 
 
 
                                                                                                                                                                                                                                                                                                                                                                                                               
第一頁 上一頁 下一頁 最後一頁 top
1. 李作英、葉美玲(2011)。乳癌發生之人口學因子與風險研究。領導護理,12(3), 26-37。〔Lee, T. Y., Yeh, M. L. (2011). A study of the demographic factor on the risk of breast cancer. Leadership Nursing, 12(3), 26-37.〕
2. 林璟宏(2013)。乳癌的化學治療。臺灣醫學,17(4),404-411。〔Lin, C. H. (2013). Chemotherapy in breast cancer. Formosan Journal of Medicine, 17(4), 404-411.〕
3. 姚開屏(2002)。台灣版世界衛生組織生活品質問卷之發展與應用。臺灣醫學, 6(2),193-200。〔Yao, K. P. (2002). Development and applications of the WHOQOL-Taiwan version. Formosan Journal of Medicine, 6(2), 193-200.〕
4. 張慈惠、黃秀梨(2000)。生活品質評量之臨床應用。臺灣醫學,4(1),86-90。〔Chang, T. H., & Hwang, S. L. (2000). Clinical application of assessment quality of life. Formosan Journal of Medicine, 4(1), 86-90.〕
5. 陳欣妤、鄭淨黛(2010)。化學治療引發周邊神經病變案例報告及文獻回顧。當代醫學,37(11),874-878。 〔Chen, H. Y., & Cheng, C. T. (2010). Chemotherapy induced peripheral neuropathy: Case report and literature review. Contemporary Medical, 37(11), 874-878.〕
6. 陳美碧、謝麗鳳、林惠蘭、李淑貞、林純如、蔡欣玲(2004)。癌症病人之生活品質及其預測因子。榮總護理,21(4),352-362。doi: 10.6142/vghn.21.4.352〔Chen, M. B., Hsieh, L. F., Lin, H. L., Lee, S. C., Lin, C. R., Tsai, S. L. (2004). Predicting factors on quality of life in cancer patients. Taipei Veterans Genera
7. 蔡盈盈、張巍鐘、陸汝斌、曹朝榮(2007)。乳癌患者主要照顧者之因應、社會支持與生活品質。臺灣精神醫學, 21(1), 43-52。〔Tsai, Y. Y., Chang, W. C., Lu, R. B., Tsao, C. J. (2007). Coping, Social Support, and Quality of Life among Primary Caregivers of Patients with Breast Cancer. Taiwanese Journal of Psychiat
 
無相關點閱論文
 
系統版面圖檔 系統版面圖檔