臺灣博碩士論文加值系統

Objectives: Review our experience in trismus release followed by free flap reconstruction after radiotherapy in oral and oropharyngeal cancer, describe the results obtained in long-term follow-up and identify possible predictors of outcome.
Methods: Interincisor distances (IIDs) where measured preoperatively (PO-IID), intraoperatively after release (IO-IID) and in the last follow-up (FU-IID). Potential predictors of outcome in terms of interincisor long-term gain (LT-gain) and postoperative loss (PO-loss) were analysed.
Results: 28 patients were included. The mean LT-gain was 8,9 ± 7,0mm, and the PO-loss was 22.14 ± 7.27mm. Patients with a PO-IID of 10mm or less had a significant higher LT-gain (p=0,038). Predictors of worse outcome included having received a previous maxillectomy during tumor ablation (lower LT-gain, p=0,035), and previous buccal mucosa resection (higher PO-loss, p=0,044).
Conclusions: Trismus release surgery and free flap reconstruction after radiotherapy seems to have moderate results with low LT-gain and a high incidence of trismus recurrence.

Recommendation Letter from the Thesis Advisor
Thesis/Disertation Oral Defense Committee Certification
Acknowledgments……………………………………………………... .iv
English Abstract………………………………………………………. ...v
Chapter 1 : Background………………………………………………….1
Section 1.1 Introduction to trismus………………………………….1
1.1.1 Definition………………………………………………...1
1.1.2 Etiology…………………………………………………..1
1.1.3 Treatment…………………………………… …………..3
Section 1.2 Trismus after Head and Neck cancer treatment………..4
1.2.1 Incidence and impact…………………………………….4
1.2.1 Risk factors………………………………………………5
1.2.3 Treatment………………………………………………...7
Chapter 2: Justification of the research………………………………….10
Chapter 3: Objectives of the study………………………………………13
Chapter 4: Material and Methods……………………………………….15
Chapter 5: Results……………………………………………………….20
Chapter 6: Discussion…………………………………………………...25
Chapter 7: Conclusions………………………………………………….34
References……………………………………………………………….36
Tables.........................................................................43


LIST OF TABLES
Chapter 5: Results tables
Table 1…………………………………………………………..43
Table 2…………………………………………………………..45
Table 3…………………………………………………………..46
Table 4…………………………………………………………..47
Table 5…………………………………………………………..48
Table 6…………………………………………………………..49

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