臺灣博碩士論文加值系統

本研究以乳膠法製備氫氧基磷灰石/鈦巨孔複合材料。首先以有機介面活性劑分子的選擇吸附，使粒子表面具有部分疏水性，能穩定於氣泡的氣-液介面，阻止鄰近氣泡互相合併及破裂，最後經乾燥、燒結即可得到複合多孔體。
選取數種介面活性劑對氫氧基磷灰石進行表面改質，由接觸角量測可得知十六胺(Hexadecylamine，HDA)的改質效果最為卓越，氫氧基磷灰石對水的接觸角可提升至90°。調整HDA濃度，接觸角隨濃度上升提高，可發現HDA濃度為4wt%時有最適當的疏水性，接觸角約75°。再將改質後的氫氧基磷灰石配置成不同固含量(3.16、4、5、6、10、15vol%)之懸浮液，利用機械攪拌法使懸浮液產生氣泡，再於1000°C進行燒結，由微結構觀測發現，隨固含量增加，複合多孔體之壁厚有增加的趨勢，並選用固含量10vol%，有較佳的強度與孔隙。
後續加入鈦粉於氫氧基磷灰石漿料中，固定HDA濃度為氫氧基磷灰石之4wt%，與固含量為10vol%，進而調整不同鈦粉比例發泡，並在700、1000、1200°C以還原氣氛進行燒結，觀察複合多孔體之微結構變化，再量測其多孔體機械性質及導電性，發現隨添加鈦比例增加有較高的機械強度，以及在1000°C燒結後複合多孔體導電性隨添加鈦比率增加而增加。

This research prepared macroporous hydroxyapatite/titanium composite foams via Pickering emulsion method. Selective adsorption of surfactant was used to make particles hydrophobic from initially hydrophilic surface. The hydrophobic particles tended to reside at the air-water interface so that bubbles were protected from coalescence, drainage and disproportionation to occur between the neighboring bubbles. Composite foams were then prepared after drying and sintering.
First, different surfactants were used to modify the surface of hydroxyapatite in water. HDA showed the best result, in which the contact angle between hydroxyapatite and water could be increase to 90°. By adjusting HDA concentration, an appropriate hydrophobicity with contact angle of 75° was obtained at 4 wt% HDA concentration. The modified hydroxyapatite was then dispensed in aqueous suspensions of different solid content (3.16, 4, 5, 6, 10, 15 vol%). After simple mechanical frothing and sintering at 1000°C, 10 vol% suspension was selected for its better strength and porosity.
Titanium powder was then added into the hydroxyapatite suspension with 4 wt% of HDA and 10 vol% of solid concentration. Microstructure, mechanical properties, and conductivity of composite foams were examined with different proportion of titanium powder at different sintering temperature (700°C、1000°C、1200°C). The mechanical strength increased with the titanium fraction, and the electrical conductivity of the composite foams sintered at 1000 °C also increased with the titanium fraction.

摘要 i
Abstract ii
目錄 iii
圖目錄 v
表目錄 vii
第一章 緒論 1
1-1 前言 1
1-2 研究動機 1
第二章 文獻回顧 2
2-1 氫氧基磷灰石結合鈦金屬於生醫之發展 2
2-2 乳膠泡沫 9
2-2-1 介面因重力產生流失(Drainage) 9
2-2-2 合併(Coalescence) 10
2-2-3 奧斯瓦爾德熟化(Ostwald Ripening) 10
2-2-4 粒子吸附 11
2-3 製備多孔陶瓷方式 12
2-3-1 複製法 12
2-3-2 犧牲模版法 13
2-3-3 直接成形法 13
2-3-4 製備氫氧基磷灰石多孔體參考文獻 15
第三章 實驗流程與分析儀器介紹 21
3-1 實驗藥品及製程設備 21
3-1-1 實驗藥品 21
3-1-2 製程儀器 22
3-2 製備氫氧基磷灰石多孔體 23
3-2-1 挑選改質氫氧基磷灰石粒子之介面活性劑 23
3-2-2 調整介面活性劑濃度 24
3-2-3 調整氫氧基磷灰石固含量製備氫氧基磷灰石多孔體 24
3-3 製備氫氧基磷灰石-鈦複合多孔體 25
3-4 多孔體機械強度量測 26
3-5 分析儀器 26
第四章 實驗結果與討論 28
4-1 氫氧機磷灰石之結構分析 28
4-1-1 氫氧機磷灰石之SEM與DLS分析 28
4-1-2 氫氧基磷灰石之XRD與EDS分析 29
4-1-3 氫氧基磷灰石之接觸角 30
4-2 奈米金屬鈦粉之結構分析 30
4-2-1 奈米金屬鈦粉之SEM與DLS分析 30
4-2-2 奈米金屬鈦粉之XRD與EDS分析 31
4-2-3 奈米金屬鈦粉之接觸角 32
4-3 氫氧基磷灰石製備多孔材料 33
4-3-1 選擇改質氫氧基磷灰石之介面活性劑 33
4-3-2 改變介面活性劑濃度對氫氧基磷灰石及鈦接觸角之影響 33
4-3-3 利用機械攪拌與燒結製備氫氧基磷灰石多孔材料 35
4-4 氫氧基磷灰石/鈦複合多孔材料 38
4-4-1 調整氫氧基磷灰石與鈦固含量比例製備複合多孔材料之SEM及EDS分析38
4-4-2 氫氧基磷灰石/鈦複合多孔材料的XRD分析 42
4-4-3 調整氫氧基磷灰石與鈦固含量比例之複合多孔材料的水銀孔隙分析 43
4-4-4 調整氫氧基磷灰石與鈦固含量比例之複合多孔材料的三點抗折分析 45
4-4-5 調整氫氧基磷灰石與鈦固含量比例之複合多孔材料的電阻測試 46
第五章 結論 47
參考文獻 48

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