Accardo, J.A. and Malow, B.A. (2015). Sleep, epilepsy, and autism. Epilepsy & behavior : E&B 47, 202-206.
Adams, J.B., Johansen, L.J., Powell, L.D., Quig, D. and Rubin, R.A. (2011). Gastrointestinal flora and gastrointestinal status in children with autism--comparisons to typical children and correlation with autism severity. BMC Gastroenterol 11, 22.
Altemus, M., Sarvaiya, N. and Neill Epperson, C. (2014). Sex differences in anxiety and depression clinical perspectives. Frontiers in neuroendocrinology 35, 320-330.
Altieri, S.C., Yang, H., O''Brien, H.J., Redwine, H.M., Senturk, D., Hensler, J.G. and Andrews, A.M. (2015). Perinatal vs genetic programming of serotonin states associated with anxiety. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 40, 1456-1470.
Amemiya, K., Dankmeyer, J.L., Fetterer, D.P., Worsham, P.L., Welkos, S.L. and Cote, C.K. (2015). Comparison of the early host immune response to two widely diverse virulent strains of Burkholderia pseudomallei that cause acute or chronic infections in BALB/c mice. Microbial pathogenesis 86, 53-63.
Angiari, S. and Constantin, G. (2013). Selectins and their ligands as potential immunotherapeutic targets in neurological diseases. Immunotherapy 5, 1207-1220.
Arreola, R., Alvarez-Herrera, S., Perez-Sanchez, G., Becerril-Villanueva, E., Cruz-Fuentes, C., Flores-Gutierrez, E.O., et al. (2016). Immunomodulatory Effects Mediated by Dopamine. Journal of immunology research 2016, 3160486.
Ashwood, P., Corbett, B.A., Kantor, A., Schulman, H., Van de Water, J. and Amaral, D.G. (2011a). In search of cellular immunophenotypes in the blood of children with autism. PloS one 6, e19299.
Ashwood, P., Krakowiak, P., Hertz-Picciotto, I., Hansen, R., Pessah, I.N. and Van de Water, J. (2011b). Associations of impaired behaviors with elevated plasma chemokines in autism spectrum disorders. J Neuroimmunol 232, 196-199.
AuCoin, D.P., Reed, D.E., Marlenee, N.L., Bowen, R.A., Thorkildson, P., Judy, B.M., et al. (2012). Polysaccharide specific monoclonal antibodies provide passive protection against intranasal challenge with Burkholderia pseudomallei. PloS one 7, e35386.
Babri, S., Doosti, M.H. and Salari, A.A. (2014). Strain-dependent effects of prenatal maternal immune activation on anxiety- and depression-like behaviors in offspring. Brain, behavior, and immunity 37, 164-176.
Banerjee, E.R. (2011). Triple selectin knockout (ELP-/-) mice fail to develop OVA-induced acute asthma phenotype. J Inflamm (Lond) 8, 19.
Barkhausen, T., Krettek, C. and van Griensven, M. (2005). L-selectin: adhesion, signalling and its importance in pathologic posttraumatic endotoxemia and non-septic inflammation. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 57, 39-52.
Beaulieu, J.M., Zhang, X., Rodriguiz, R.M., Sotnikova, T.D., Cools, M.J., Wetsel, W.C., et al. (2008). Role of GSK3 beta in behavioral abnormalities induced by serotonin deficiency. Proceedings of the National Academy of Sciences of the United States of America 105, 1333-1338.
Becker, K.G. (2007). Autism, asthma, inflammation, and the hygiene hypothesis. Med Hypotheses 69, 731-740.
Billeci, L., Tonacci, A., Tartarisco, G., Ruta, L., Pioggia, G. and Gangemi, S. (2015). Association Between Atopic Dermatitis and Autism Spectrum Disorders: A Systematic Review. Am J Clin Dermatol 16, 371-388.
Bogdanik, L.P., Chapman, H.D., Miers, K.E., Serreze, D.V. and Burgess, R.W. (2012). A MusD retrotransposon insertion in the mouse Slc6a5 gene causes alterations in neuromuscular junction maturation and behavioral phenotypes. PloS one 7, e30217.
Boksa, P. (2010). Effects of prenatal infection on brain development and behavior: a review of findings from animal models. Brain, behavior, and immunity 24, 881-897.
Braniste, V., Al-Asmakh, M., Kowal, C., Anuar, F., Abbaspour, A., Toth, M., et al. (2014). The gut microbiota influences blood-brain barrier permeability in mice. Sci Transl Med 6, 263ra158.
Brett, P.J., Burtnick, M.N., Snyder, D.S., Shannon, J.G., Azadi, P. and Gherardini, F.C. (2007). Burkholderia mallei expresses a unique lipopolysaccharide mixture that is a potent activator of human Toll-like receptor 4 complexes. Molecular microbiology 63, 379-390.
Camara, M.L., Corrigan, F., Jaehne, E.J., Jawahar, M.C., Anscomb, H., Koerner, H. and Baune, B.T. (2013). TNF-alpha and its receptors modulate complex behaviours and neurotrophins in transgenic mice. Psychoneuroendocrinology 38, 3102-3114.
Careaga, M., Murai, T. and Bauman, M.D. (2017). Maternal Immune Activation and Autism Spectrum Disorder: From Rodents to Nonhuman and Human Primates. Biological psychiatry 81, 391-401.
Caroff, M., Karibian, D., Cavaillon, J.M. and Haeffner-Cavaillon, N. (2002). Structural and functional analyses of bacterial lipopolysaccharides. Microbes and infection / Institut Pasteur 4, 915-926.
Carvey, P.M., Chang, Q., Lipton, J.W. and Ling, Z. (2003). Prenatal exposure to the bacteriotoxin lipopolysaccharide leads to long-term losses of dopamine neurons in offspring: a potential, new model of Parkinson''s disease. Frontiers in bioscience : a journal and virtual library 8, s826-837.
Castillo, A., Kramer, N., Schwartz, C.E., Miles, J.H., DuPont, B.R., Rosenfeld, J.A. and Graham, J.M., Jr. (2014). 19q13.32 microdeletion syndrome: three new cases. European journal of medical genetics 57, 654-658.
Catana, C.S., Berindan Neagoe, I., Cozma, V., Magdas, C., Tabaran, F. and Dumitrascu, D.L. (2015). Contribution of the IL-17/IL-23 axis to the pathogenesis of inflammatory bowel disease. World J Gastroenterol 21, 5823-5830.
Cazareth, J., Guyon, A., Heurteaux, C., Chabry, J. and Petit-Paitel, A. (2014). Molecular and cellular neuroinflammatory status of mouse brain after systemic lipopolysaccharide challenge: importance of CCR2/CCL2 signaling. Journal of neuroinflammation 11, 132.
Cebra, J.J. (1999). Influences of microbiota on intestinal immune system development. Am J Clin Nutr 69, 1046S-1051S.
Chaidez, V., Hansen, R.L. and Hertz-Picciotto, I. (2014). Gastrointestinal problems in children with autism, developmental delays or typical development. Journal of autism and developmental disorders 44, 1117-1127.
Chakravarty, S. and Herkenham, M. (2005). Toll-like receptor 4 on nonhematopoietic cells sustains CNS inflammation during endotoxemia, independent of systemic cytokines. The Journal of neuroscience : the official journal of the Society for Neuroscience 25, 1788-1796.
Chamberlain, R.S. and Herman, B.H. (1990). A novel biochemical model linking dysfunctions in brain melatonin, proopiomelanocortin peptides, and serotonin in autism. Biological psychiatry 28, 773-793.
Chang, E.Y., Zhang, J., Sullivan, S., Newman, R. and Singh, I. (2011). N-acetylcysteine attenuates the maternal and fetal proinflammatory response to intrauterine LPS injection in an animal model for preterm birth and brain injury. J Matern Fetal Neonatal Med 24, 732-740.
Chantratita, N., Tandhavanant, S., Myers, N.D., Seal, S., Arayawichanont, A., Kliangsa-Ad, A., et al. (2013). Survey of innate immune responses to Burkholderia pseudomallei in human blood identifies a central role for lipopolysaccharide. PloS one 8, e81617.
Chen, L. and Flies, D.B. (2013). Molecular mechanisms of T cell co-stimulation and co-inhibition. Nature reviews. Immunology 13, 227-242.
Chen, Y.S., Lin, H.H., Hsueh, P.T., Liu, P.J., Ni, W.F., Chung, W.C., et al. (2015). Whole-Genome Sequence of an Epidemic Strain of Burkholderia pseudomallei vgh07 in Taiwan. Genome announcements 3.
Chen, Y.S., Lin, H.H., Hsueh, P.T., Ni, W.F., Liu, P.J., Chen, P.S., et al. (2016). Involvement of L-selectin expression in Burkholderia pseudomallei-infected monocytes invading the brain during murine melioidosis. Virulence, 1-16.
Chen, Y.S., Lin, H.H., Liu, P.J., Tsai, H.Y., Hsueh, P.T., Liu, H.Y. and Chen, Y.L. (2011). Use of 3-hydroxy fatty acid concentrations in a murine air pouch infection model as a surrogate marker for LPS activity: a feasibility study using environmental Burkholderia cenocepacia isolates. Journal of microbiological methods 87, 368-374.
Choi, G.B., Yim, Y.S., Wong, H., Kim, S., Kim, H., Kim, S.V., et al. (2016). The maternal interleukin-17a pathway in mice promotes autism-like phenotypes in offspring. Science (New York, N.Y.) 351, 933-939.
Chow, M. and Cao, M. (2016). The hypocretin/orexin system in sleep disorders: preclinical insights and clinical progress. Nat Sci Sleep 8, 81-86.
Claustrat, B. and Leston, J. (2015). Melatonin: Physiological effects in humans. Neuro-Chirurgie 61, 77-84.
Conroy, S.M., Nguyen, V., Quina, L.A., Blakely-Gonzales, P., Ur, C., Netzeband, J.G., et al. (2004). Interleukin-6 produces neuronal loss in developing cerebellar granule neuron cultures. J Neuroimmunol 155, 43-54.
Coutinho, A.M., Oliveira, G., Morgadinho, T., Fesel, C., Macedo, T.R., Bento, C., et al. (2004). Variants of the serotonin transporter gene (SLC6A4) significantly contribute to hyperserotonemia in autism. Molecular psychiatry 9, 264-271.
Croonenberghs, J., Wauters, A., Devreese, K., Verkerk, R., Scharpe, S., Bosmans, E., et al. (2002). Increased serum albumin, gamma globulin, immunoglobulin IgG, and IgG2 and IgG4 in autism. Psychol Med 32, 1457-1463.
Csordas, T., Bertok, L. and Csapo, Z. (1978). Experiments on prevention of the endotoxin-abortifacient effect by radiodetoxified endotoxin pretreatment in rats. Gynecologic and obstetric investigation 9, 57-64.
Dantzer, R. (2009). Cytokine, sickness behavior, and depression. Immunology and allergy clinics of North America 29, 247-264.
Davis, M.R., Jr. and Goldberg, J.B. (2012). Purification and visualization of lipopolysaccharide from Gram-negative bacteria by hot aqueous-phenol extraction. Journal of visualized experiments : JoVE.
de Magistris, L., Familiari, V., Pascotto, A., Sapone, A., Frolli, A., Iardino, P., et al. (2010). Alterations of the intestinal barrier in patients with autism spectrum disorders and in their first-degree relatives. J Pediatr Gastroenterol Nutr 51, 418-424.
de Pablo, R., Monserrat, J., Reyes, E., Diaz, D., Rodriguez-Zapata, M., de la Hera, A., et al. (2013). Circulating sICAM-1 and sE-Selectin as biomarker of infection and prognosis in patients with systemic inflammatory response syndrome. European journal of internal medicine 24, 132-138.
De Soyza, A., Ellis, C.D., Khan, C.M., Corris, P.A. and Demarco de Hormaeche, R. (2004). Burkholderia cenocepacia lipopolysaccharide, lipid A, and proinflammatory activity. Am J Respir Crit Care Med 170, 70-77.
de Theije, C.G., Wu, J., Koelink, P.J., Korte-Bouws, G.A., Borre, Y., Kas, M.J., et al. (2014). Autistic-like behavioural and neurochemical changes in a mouse model of food allergy. Behav Brain Res 261, 265-274.
Depino, A.M. (2015). Early prenatal exposure to LPS results in anxiety- and depression-related behaviors in adulthood. Neuroscience 299, 56-65.
Dicksved, J., Schreiber, O., Willing, B., Petersson, J., Rang, S., Phillipson, M., et al. (2012). Lactobacillus reuteri maintains a functional mucosal barrier during DSS treatment despite mucus layer dysfunction. PloS one 7, e46399.
Ding, H.T., Taur, Y. and Walkup, J.T. (2017). Gut Microbiota and Autism: Key Concepts and Findings. Journal of autism and developmental disorders 47, 480-489.
Dufour-Rainfray, D., Vourc''h, P., Le Guisquet, A.M., Garreau, L., Ternant, D., Bodard, S., et al. (2010). Behavior and serotonergic disorders in rats exposed prenatally to valproate: a model for autism. Neurosci Lett 470, 55-59.
Eisenstein, M. (2016). Microbiome: Bacterial broadband. Nature 533, S104-106.
Eskow Jaunarajs, K.L., George, J.A. and Bishop, C. (2012). L-DOPA-induced dysregulation of extrastriatal dopamine and serotonin and affective symptoms in a bilateral rat model of Parkinson''s disease. Neuroscience 218, 243-256.
Estes, M.L. and McAllister, A.K. (2016). Maternal immune activation: Implications for neuropsychiatric disorders. Science (New York, N.Y.) 353, 772-777.
Fairless, A.H., Katz, J.M., Vijayvargiya, N., Dow, H.C., Kreibich, A.S., Berrettini, W.H., et al. (2013). Development of home cage social behaviors in BALB/cJ vs. C57BL/6J mice. Behavioural brain research 237, 338-347.
Fernandez, S.P. and Gaspar, P. (2012). Investigating anxiety and depressive-like phenotypes in genetic mouse models of serotonin depletion. Neuropharmacology 62, 144-154.
Finegold, S.M., Summanen, P.H., Downes, J., Corbett, K., Komoriya, T., Strati, F., et al. (2017). Detection of Clostridium perfringens toxin genes in the gut microbiota of autistic children
New evidences on the altered gut microbiota in autism spectrum disorders. Anaerobe 5, 24.
Fiorentino, M., Sapone, A., Senger, S., Camhi, S.S., Kadzielski, S.M., Buie, T.M., et al. (2016). Blood-brain barrier and intestinal epithelial barrier alterations in autism spectrum disorders. Mol Autism 7, 49.
Fontaine, V., Mohand-Said, S., Hanoteau, N., Fuchs, C., Pfizenmaier, K. and Eisel, U. (2002). Neurodegenerative and neuroprotective effects of tumor Necrosis factor (TNF) in retinal ischemia: opposite roles of TNF receptor 1 and TNF receptor 2. The Journal of neuroscience : the official journal of the Society for Neuroscience 22, RC216.
Frank, D.N., St Amand, A.L., Feldman, R.A., Boedeker, E.C., Harpaz, N. and Pace, N.R. (2007). Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases. Proceedings of the National Academy of Sciences of the United States of America 104, 13780-13785.
Frye, R.E., Rose, S., Slattery, J. and MacFabe, D.F. (2015). Gastrointestinal dysfunction in autism spectrum disorder: the role of the mitochondria and the enteric microbiome. Microb Ecol Health Dis 26, 27458.
Ganesan, S. and Sajjan, U.S. (2011). Host evasion by Burkholderia cenocepacia. Frontiers in cellular and infection microbiology 1, 25.
Gentile, M.T., Nawa, Y., Lunardi, G., Florio, T., Matsui, H. and Colucci-D''Amato, L. (2012). Tryptophan hydroxylase 2 (TPH2) in a neuronal cell line: modulation by cell differentiation and NRSF/rest activity. Journal of neurochemistry 123, 963-970.
Glass, M.B., Gee, J.E., Steigerwalt, A.G., Cavuoti, D., Barton, T., Hardy, R.D., et al. (2006). Pneumonia and septicemia caused by Burkholderia thailandensis in the United States. Journal of clinical microbiology 44, 4601-4604.
Gordon, S. and Taylor, P.R. (2005). Monocyte and macrophage heterogeneity. Nat Rev Immunol 5, 953-964.
Gorrindo, P., Williams, K.C., Lee, E.B., Walker, L.S., McGrew, S.G. and Levitt, P. (2012). Gastrointestinal dysfunction in autism: parental report, clinical evaluation, and associated factors. Autism Res 5, 101-108.
Gu, F., Chauhan, V. and Chauhan, A. (2017). Monoamine oxidase-A and B activities in the cerebellum and frontal cortex of children and young adults with autism. Journal of neuroscience research.
Gupta, S., Aggarwal, S., Rashanravan, B. and Lee, T. (1998). Th1- and Th2-like cytokines in CD4+ and CD8+ T cells in autism. J Neuroimmunol 85, 106-109.
Halle, M., Tribout-Jover, P., Lanteigne, A.M., Boulais, J., St-Jean, J.R., Jodoin, R., et al. (2015). Methods to monitor monocytes-mediated amyloid-beta uptake and phagocytosis in the context of adjuvanted immunotherapies. J Immunol Methods 424, 64-79.
Han, Y.M., Cheung, W.K., Wong, C.K., Sze, S.L., Cheng, T.W., Yeung, M.K. and Chan, A.S. (2017). Distinct Cytokine and Chemokine Profiles in Autism Spectrum Disorders. Front Immunol 8, 11.
Haque, A., Easton, A., Smith, D., O''Garra, A., Van Rooijen, N., Lertmemongkolchai, G., et al. (2006). Role of T cells in innate and adaptive immunity against murine Burkholderia pseudomallei infection. The Journal of infectious diseases 193, 370-379.
Harry, G.J. and Kraft, A.D. (2012). Microglia in the developing brain: a potential target with lifetime effects. Neurotoxicology 33, 191-206.
Hava, G., Vered, L., Yael, M., Mordechai, H. and Mahoud, H. (2006). Alterations in behavior in adult offspring mice following maternal inflammation during pregnancy. Developmental psychobiology 48, 162-168.
Holtmann, G.J., Ford, A.C. and Talley, N.J. (2016). Pathophysiology of irritable bowel syndrome. Lancet Gastroenterol Hepatol 1, 133-146.
Hong, H., Kim, B.S. and Im, H.I. (2016). Pathophysiological Role of Neuroinflammation in Neurodegenerative Diseases and Psychiatric Disorders. International neurourology journal 20, S2-7.
Howerton, C.L. and Bale, T.L. (2012). Prenatal programing: at the intersection of maternal stress and immune activation. Hormones and behavior 62, 237-242.
Hsueh, P.T., Liu, C.L., Wang, H.H., Ni, W.F., Chen, Y.L. and Liu, J.K. (2016). A comparison of the immunological potency of Burkholderia lipopolysaccharides in endotoxemic BALB/c mice. Microbiology and immunology 60, 725-739.
Hsueh, P.T., Liu, J.K., Chen, Y.L., Liu, P.J., Ni, W.F., Chen, Y.S., et al. (2015). Genomic Sequence of Burkholderia multivorans NKI379, a Soil Bacterium That Inhibits the Growth of Burkholderia pseudomallei. Genome announcements 3.
Hughes, J.E., Stewart, J., Barclay, G.R. and Govan, J.R. (1997). Priming of neutrophil respiratory burst activity by lipopolysaccharide from Burkholderia cepacia. Infection and immunity 65, 4281-4287.
Hume, D.A. (2015). The Many Alternative Faces of Macrophage Activation. Frontiers in immunology 6, 370.
Hunn, J.P., Feng, C.G., Sher, A. and Howard, J.C. (2011). The immunity-related GTPases in mammals: a fast-evolving cell-autonomous resistance system against intracellular pathogens. Mamm Genome 22, 43-54.
Ierano, T., Cescutti, P., Leone, M.R., Luciani, A., Rizzo, R., Raia, V., et al. (2010). The lipid A of Burkholderia multivorans C1576 smooth-type lipopolysaccharide and its pro-inflammatory activity in a cystic fibrosis airways model. Innate immunity 16, 354-365.
Ierano, T., Silipo, A., Sturiale, L., Garozzo, D., Brookes, H., Khan, C.M., et al. (2008). The structure and proinflammatory activity of the lipopolysaccharide from Burkholderia multivorans and the differences between clonal strains colonizing pre and posttransplanted lungs. Glycobiology 18, 871-881.
Iwata, Y., Tsuchiya, K.J., Mikawa, S., Nakamura, K., Takai, Y., Suda, S., et al. (2008). Serum levels of P-selectin in men with high-functioning autism. Br J Psychiatry 193, 338-339.
Jaiswal, P., Mohanakumar, K.P. and Rajamma, U. (2015). Serotonin mediated immunoregulation and neural functions: Complicity in the aetiology of autism spectrum disorders. Neuroscience and biobehavioral reviews 55, 413-431.
Jiang, Z., Georgel, P., Du, X., Shamel, L., Sovath, S., Mudd, S., et al. (2005). CD14 is required for MyD88-independent LPS signaling. Nature immunology 6, 565-570.
Jones, K.L., Will, M.J., Hecht, P.M., Parker, C.L. and Beversdorf, D.Q. (2013). Maternal diet rich in omega-6 polyunsaturated fatty acids during gestation and lactation produces autistic-like sociability deficits in adult offspring. Behavioural brain research 238, 193-199.
Juttler, E., Tarabin, V. and Schwaninger, M. (2002). Interleukin-6 (IL-6): a possible neuromodulator induced by neuronal activity. Neuroscientist 8, 268-275.
Kameno, Y., Iwata, K., Matsuzaki, H., Miyachi, T., Tsuchiya, K.J., Matsumoto, K., et al. (2013). Serum levels of soluble platelet endothelial cell adhesion molecule-1 and vascular cell adhesion molecule-1 are decreased in subjects with autism spectrum disorder. Mol Autism 4, 19.
Kang, D.W., Adams, J.B., Gregory, A.C., Borody, T., Chittick, L., Fasano, A., et al. (2017). Microbiota Transfer Therapy alters gut ecosystem and improves gastrointestinal and autism symptoms: an open-label study. Microbiome 5, 10.
Karrow, N.A. (2006). Activation of the hypothalamic-pituitary-adrenal axis and autonomic nervous system during inflammation and altered programming of the neuroendocrine-immune axis during fetal and neonatal development: lessons learned from the model inflammagen, lipopolysaccharide. Brain, behavior, and immunity 20, 144-158.
Kerns, C.M., Kendall, P.C., Berry, L., Souders, M.C., Franklin, M.E., Schultz, R.T., et al. (2014). Traditional and atypical presentations of anxiety in youth with autism spectrum disorder. Journal of autism and developmental disorders 44, 2851-2861.
Kezurer, N., Galron, D. and Golan, H.M. (2013). Increased susceptibility to mild neonatal stress in MTHFR deficient mice. Behavioural brain research 253, 240-252.
Khananshvili, D. (2013). The SLC8 gene family of sodium-calcium exchangers (NCX) - structure, function, and regulation in health and disease. Molecular aspects of medicine 34, 220-235.
Kim, Y.S., Leventhal, B.L., Koh, Y.J., Fombonne, E., Laska, E., Lim, E.C., et al. (2011). Prevalence of autism spectrum disorders in a total population sample. The American journal of psychiatry 168, 904-912.
Kleine, T.O. and Benes, L. (2006). Immune surveillance of the human central nervous system (CNS): different migration pathways of immune cells through the blood-brain barrier and blood-cerebrospinal fluid barrier in healthy persons. Cytometry A 69, 147-151.
Klindworth, A., Pruesse, E., Schweer, T., Peplies, J., Quast, C., Horn, M. and Glockner, F.O. (2013). Evaluation of general 16S ribosomal RNA gene PCR primers for classical and next-generation sequencing-based diversity studies. Nucleic Acids Res 41, e1.
Komada, M., Takao, K. and Miyakawa, T. (2008). Elevated plus maze for mice. J Vis Exp.
Kraneveld, A.D., Szklany, K., de Theije, C.G. and Garssen, J. (2016). Gut-to-Brain Axis in Autism Spectrum Disorders: Central Role for the Microbiome. Int Rev Neurobiol 131, 263-287.
Krishna, S., Dodd, C.A. and Filipov, N.M. (2016). Behavioral and monoamine perturbations in adult male mice with chronic inflammation induced by repeated peripheral lipopolysaccharide administration. Behavioural brain research 302, 279-290.
Kubesova, A., Tejkalova, H., Syslova, K., Kacer, P., Vondrousova, J., Tyls, F., et al. (2015). Biochemical, histopathological and morphological profiling of a rat model of early immune stimulation: relation to psychopathology. PloS one 10, e0115439.
Kumar, H., Kawai, T. and Akira, S. (2011). Pathogen recognition by the innate immune system. International reviews of immunology 30, 16-34.
Kung, C.T., Hsiao, S.Y., Su, C.M., Tsai, T.C., Cheng, H.H., Tsai, N.W., et al. (2013). Serum adhesion molecules as predictors of bacteremia in adult severe sepsis patients at the emergency department. Clinica chimica acta; international journal of clinical chemistry 421, 116-120.
Lambert, J.F., Benoit, B.O., Colvin, G.A., Carlson, J., Delville, Y. and Quesenberry, P.J. (2000). Quick sex determination of mouse fetuses. Journal of neuroscience methods 95, 127-132.
Laws, T.R., Smither, S.J., Lukaszewski, R.A. and Atkins, H.S. (2011). Neutrophils are the predominant cell-type to associate with Burkholderia pseudomallei in a BALB/c mouse model of respiratory melioidosis. Microbial pathogenesis 51, 471-475.
Levy, Y. and Ebstein, R.P. (2009). Research review: crossing syndrome boundaries in the search for brain endophenotypes. J Child Psychol Psychiatry 50, 657-668.
Li, Q., Han, Y., Dy, A.B.C. and Hagerman, R.J. (2017). The Gut Microbiota and Autism Spectrum Disorders. Frontiers in cellular neuroscience 11, 120.
Li, X., Chauhan, A., Sheikh, A.M., Patil, S., Chauhan, V., Li, X.M., et al. (2009). Elevated immune response in the brain of autistic patients. J Neuroimmunol 207, 111-116.
Li, Z., Chalazonitis, A., Huang, Y.Y., Mann, J.J., Margolis, K.G., Yang, Q.M., et al. (2011). Essential roles of enteric neuronal serotonin in gastrointestinal motility and the development/survival of enteric dopaminergic neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience 31, 8998-9009.
Lin, H.H., Chen, Y.S., Li, Y.C., Tseng, I.L., Hsieh, T.H., Buu, L.M. and Chen, Y.L. (2011). Burkholderia multivorans acts as an antagonist against the growth of Burkholderia pseudomallei in soil. Microbiology and immunology 55, 616-624.
Lin, H.H., Huang, S.P., Hsieh, H.C., Chen, C.S. and Chen, Y.L. (2007). Performance characteristics of the limulus amebocyte lysate assay and gas chromatography-mass spectrum analysis of lipopolysaccharides relative to nitric oxide production by peritoneal exudates of cells. Journal of hazardous materials 145, 431-436.
Liu, P.J., Chen, Y.S., Lin, H.H., Ni, W.F., Hsieh, T.H., Chen, H.T. and Chen, Y.L. (2013). Induction of mouse melioidosis with meningitis by CD11b+ phagocytic cells harboring intracellular B. pseudomallei as a Trojan horse. PLoS Negl Trop Dis 7, e2363.
Loutet, S.A. and Valvano, M.A. (2010). A decade of Burkholderia cenocepacia virulence determinant research. Infection and immunity 78, 4088-4100.
Lowry, C.A., Johnson, P.L., Hay-Schmidt, A., Mikkelsen, J. and Shekhar, A. (2005). Modulation of anxiety circuits by serotonergic systems. Stress (Amsterdam, Netherlands) 8, 233-246.
Maes, P.W., Rodrigues, P.A., Oliver, R., Mott, B.M. and Anderson, K.E. (2016). Diet-related gut bacterial dysbiosis correlates with impaired development, increased mortality and Nosema disease in the honeybee (Apis mellifera). Mol Ecol 25, 5439-5450.
Maeshima, N. and Fernandez, R.C. (2013). Recognition of lipid A variants by the TLR4-MD-2 receptor complex. Frontiers in cellular and infection microbiology 3, 3.
Magalhaes, E.S., Pinto-Mariz, F., Bastos-Pinto, S., Pontes, A.T., Prado, E.A. and deAzevedo, L.C. (2009). Immune allergic response in Asperger syndrome. J Neuroimmunol 216, 108-112.
Malinen, E., Krogius-Kurikka, L., Lyra, A., Nikkila, J., Jaaskelainen, A., Rinttila, T., et al. (2010). Association of symptoms with gastrointestinal microbiota in irritable bowel syndrome. World J Gastroenterol 16, 4532-4540.
Manwani, B., Liu, F., Xu, Y., Persky, R., Li, J. and McCullough, L.D. (2011). Functional recovery in aging mice after experimental stroke. Brain, behavior, and immunity 25, 1689-1700.
Martin, E.R., Menold, M.M., Wolpert, C.M., Bass, M.P., Donnelly, S.L., Ravan, S.A., et al. (2000). Analysis of linkage disequilibrium in gamma-aminobutyric acid receptor subunit genes in autistic disorder. American journal of medical genetics 96, 43-48.
Matson, J.L., Rieske, R.D. and Williams, L.W. (2013). The relationship between autism spectrum disorders and attention-deficit/hyperactivity disorder: an overview. Res Dev Disabil 34, 2475-2484.
Mayer, E.A., Padua, D. and Tillisch, K. (2014). Altered brain-gut axis in autism: comorbidity or causative mechanisms? Bioessays 36, 933-939.
McElhanon, B.O., McCracken, C., Karpen, S. and Sharp, W.G. (2014). Gastrointestinal symptoms in autism spectrum disorder: a meta-analysis. Pediatrics 133, 872-883.
Meumann, E.M., Cheng, A.C., Ward, L. and Currie, B.J. (2012). Clinical features and epidemiology of melioidosis pneumonia: results from a 21-year study and review of the literature. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 54, 362-369.
Molloy, C.A., Morrow, A.L., Meinzen-Derr, J., Schleifer, K., Dienger, K., Manning-Courtney, P., et al. (2006). Elevated cytokine levels in children with autism spectrum disorder. J Neuroimmunol 172, 198-205.
Money, K.M. and Stanwood, G.D. (2013). Developmental origins of brain disorders: roles for dopamine. Frontiers in cellular neuroscience 7, 260.
Morgan, E., Varro, R., Sepulveda, H., Ember, J.A., Apgar, J., Wilson, J., et al. (2004). Cytometric bead array: a multiplexed assay platform with applications in various areas of biology. Clinical immunology (Orlando, Fla.) 110, 252-266.
Mundy, P., Gwaltney, M. and Henderson, H. (2010). Self-referenced processing, neurodevelopment and joint attention in autism. Autism 14, 408-429.
Ngugi, S.A., Ventura, V.V., Qazi, O., Harding, S.V., Kitto, G.B., Estes, D.M., et al. (2010). Lipopolysaccharide from Burkholderia thailandensis E264 provides protection in a murine model of melioidosis. Vaccine 28, 7551-7555.
Novem, V., Shui, G., Wang, D., Bendt, A.K., Sim, S.H., Liu, Y., et al. (2009). Structural and biological diversity of lipopolysaccharides from Burkholderia pseudomallei and Burkholderia thailandensis. Clinical and vaccine immunology : CVI 16, 1420-1428.
Onore, C.E., Nordahl, C.W., Young, G.S., Van de Water, J.A., Rogers, S.J. and Ashwood, P. (2012). Levels of soluble platelet endothelial cell adhesion molecule-1 and P-selectin are decreased in children with autism spectrum disorder. Biological psychiatry 72, 1020-1025.
Onore, C.E., Schwartzer, J.J., Careaga, M., Berman, R.F. and Ashwood, P. (2014). Maternal immune activation leads to activated inflammatory macrophages in offspring. Brain, behavior, and immunity 38, 220-226.
Ornoy, A., Weinstein-Fudim, L. and Ergaz, Z. (2016). Genetic Syndromes, Maternal Diseases and Antenatal Factors Associated with Autism Spectrum Disorders (ASD). Front Neurosci 10, 316.
Ossenkopp, K.P., Foley, K.A., Gibson, J., Fudge, M.A., Kavaliers, M., Cain, D.P. and Macfabe, D.F. (2012). Systemic treatment with the enteric bacterial fermentation product, propionic acid, produces both conditioned taste avoidance and conditioned place avoidance in rats. Behavioural brain research 227, 134-141.
Palmer, A.M., Degano, A.L., Park, M.J., Ramamurthy, S. and Ronnett, G.V. (2012). Normal mitral cell dendritic development in the setting of Mecp2 mutation. Neuroscience 202, 108-116.
Pardo, C.A., Vargas, D.L. and Zimmerman, A.W. (2005). Immunity, neuroglia and neuroinflammation in autism. Int Rev Psychiatry 17, 485-495.
Parracho, H.M., Bingham, M.O., Gibson, G.R. and McCartney, A.L. (2005). Differences between the gut microflora of children with autistic spectrum disorders and that of healthy children. J Med Microbiol 54, 987-991.
Pennisi, M., Crupi, R., Di Paola, R., Ontario, M.L., Bella, R., Calabrese, E.J., et al. (2017). Inflammasomes, hormesis, and antioxidants in neuroinflammation: Role of NRLP3 in Alzheimer disease. Journal of neuroscience research 95, 1360-1372.
Pernot, F., Dorandeu, F., Beaup, C. and Peinnequin, A. (2010). Selection of reference genes for real-time quantitative reverse transcription-polymerase chain reaction in hippocampal structure in a murine model of temporal lobe epilepsy with focal seizures. Journal of neuroscience research 88, 1000-1008.
Planas, A.M., Gorina, R. and Chamorro, A. (2006). Signalling pathways mediating inflammatory responses in brain ischaemia. Biochem Soc Trans 34, 1267-1270.
Power, D., Santoso, N., Dieringer, M., Yu, J., Huang, H., Simpson, S., et al. (2015). IFI44 suppresses HIV-1 LTR promoter activity and facilitates its latency. Virology 481, 142-150.
Ratajczak, H.V. (2011). Theoretical aspects of autism: biomarkers--a review. Journal of immunotoxicology 8, 80-94.
Rath, M.F., Coon, S.L., Amaral, F.G., Weller, J.L., Moller, M. and Klein, D.C. (2016). Melatonin Synthesis: Acetylserotonin O-Methyltransferase (ASMT) Is Strongly Expressed in a Subpopulation of Pinealocytes in the Male Rat Pineal Gland. Endocrinology 157, 2028-2040.
Romo-Gonzalez, T., Chavarria, A. and Perez, H.J. (2012). Central nervous system: a modified immune surveillance circuit? Brain, behavior, and immunity 26, 823-829.
Rousseau, F., Aubrey, K.R. and Supplisson, S. (2008). The glycine transporter GlyT2 controls the dynamics of synaptic vesicle refilling in inhibitory spinal cord neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience 28, 9755-9768.
Sakowski, S.A., Geddes, T.J., Thomas, D.M., Levi, E., Hatfield, J.S. and Kuhn, D.M. (2006). Differential tissue distribution of tryptophan hydroxylase isoforms 1 and 2 as revealed with monospecific antibodies. Brain research 1085, 11-18.
Saldias, M.S., Ortega, X. and Valvano, M.A. (2009). Burkholderia cenocepacia O antigen lipopolysaccharide prevents phagocytosis by macrophages and adhesion to epithelial cells. Journal of medical microbiology 58, 1542-1548.
Samuelsson, A.M., Jennische, E., Hansson, H.A. and Holmang, A. (2006). Prenatal exposure to interleukin-6 results in inflammatory neurodegeneration in hippocampus with NMDA/GABA(A) dysregulation and impaired spatial learning. Am J Physiol Regul Integr Comp Physiol 290, R1345-1356.
Samuelsson, A.M., Ohrn, I., Dahlgren, J., Eriksson, E., Angelin, B., Folkow, B. and Holmang, A. (2004). Prenatal exposure to interleukin-6 results in hypertension and increased hypothalamic-pituitary-adrenal axis activity in adult rats. Endocrinology 145, 4897-4911.
Sandler, R.H., Finegold, S.M., Bolte, E.R., Buchanan, C.P., Maxwell, A.P., Vaisanen, M.L., et al. (2000). Short-term benefit from oral vancomycin treatment of regressive-onset autism. J Child Neurol 15, 429-435.
Sens, J., Schneider, E., Mauch, J., Schaffstein, A., Mohamed, S., Fasoli, K., et al. (2017). Lipopolysaccharide administration induces sex-dependent behavioural and serotonergic neurochemical signatures in mice. Pharmacology, biochemistry, and behavior 153, 168-181.
Shaw, W. (2010). Increased urinary excretion of a 3-(3-hydroxyphenyl)-3-hydroxypropionic acid (HPHPA), an abnormal phenylalanine metabolite of Clostridia spp. in the gastrointestinal tract, in urine samples from patients with autism and schizophrenia. Nutr Neurosci 13, 135-143.
Silipo, A., Molinaro, A., Ierano, T., De Soyza, A., Sturiale, L., Garozzo, D., et al. (2007). The complete structure and pro-inflammatory activity of the lipooligosaccharide of the highly epidemic and virulent gram-negative bacterium Burkholderia cenocepacia ET-12 (strain J2315). Chemistry (Weinheim an der Bergstrasse, Germany) 13, 3501-3511.
Simchovitz, A., Heneka, M.T. and Soreq, H. (2017). Personalized genetics of the cholinergic blockade of neuroinflammation. Journal of neurochemistry.
Simic, G., Babic Leko, M., Wray, S., Harrington, C.R., Delalle, I., Jovanov-Milosevic, N., et al. (2017). Monoaminergic neuropathology in Alzheimer''s disease. Progress in neurobiology 151, 101-138.
Simsek, S., Cetin, I., Cim, A. and Kaya, S. (2016). Elevated levels of tissue plasminogen activator and E-selectin in male children with autism spectrum disorder. Autism Res 9, 1241-1247.
Sliwinski, S., Croonenberghs, J., Christophe, A., Deboutte, D. and Maes, M. (2006). Polyunsaturated fatty acids: do they have a role in the pathophysiology of autism? Neuro Endocrinol Lett 27, 465-471.
Sofroniew, M.V. and Vinters, H.V. (2010). Astrocytes: biology and pathology. Acta neuropathologica 119, 7-35.
Son, J.S., Zheng, L.J., Rowehl, L.M., Tian, X., Zhang, Y., Zhu, W., et al. (2015). Comparison of Fecal Microbiota in Children with Autism Spectrum Disorders and Neurotypical Siblings in the Simons Simplex Collection. PloS one 10, e0137725.
Staley, C., Kelly, C.R., Brandt, L.J., Khoruts, A. and Sadowsky, M.J. (2016). Complete Microbiota Engraftment Is Not Essential for Recovery from Recurrent Clostridium difficile Infection following Fecal Microbiota Transplantation. MBio 7.
Stansley, B.J. and Yamamoto, B.K. (2013). L-dopa-induced dopamine synthesis and oxidative stress in serotonergic cells. Neuropharmacology 67, 243-251.
Stilling, R.M., Dinan, T.G. and Cryan, J.F. (2014). Microbial genes, brain & behaviour - epigenetic regulation of the gut-brain axis. Genes Brain Behav 13, 69-86.
Stilling, R.M., Ryan, F.J., Hoban, A.E., Shanahan, F., Clarke, G., Claesson, M.J., et al. (2015). Microbes & neurodevelopment--Absence of microbiota during early life increases activity-related transcriptional pathways in the amygdala. Brain, behavior, and immunity 50, 209-220.
Strati, F., Cavalieri, D., Albanese, D., De Felice, C., Donati, C., Hayek, J., et al. (2017). New evidences on the altered gut microbiota in autism spectrum disorders. Microbiome 5, 24.
Swanberg, S.E., Nagarajan, R.P., Peddada, S., Yasui, D.H. and LaSalle, J.M. (2009). Reciprocal co-regulation of EGR2 and MECP2 is disrupted in Rett syndrome and autism. Hum Mol Genet 18, 525-534.
Takao, K. and Miyakawa, T. (2006). Light/dark transition test for mice. J Vis Exp, 104.
Takeshima, M., Miyazaki, I., Murakami, S., Kita, T. and Asanuma, M. (2016). l-Theanine protects against excess dopamine-induced neurotoxicity in the presence of astrocytes. Journal of clinical biochemistry and nutrition 59, 93-99.
Tang, J., Yu, Y. and Yang, W. (2017). Long noncoding RNA and its contribution to autism spectrum disorders. CNS Neurosci Ther.
Thomas, R.H., Meeking, M.M., Mepham, J.R., Tichenoff, L., Possmayer, F., Liu, S. and MacFabe, D.F. (2012). The enteric bacterial metabolite propionic acid alters brain and plasma phospholipid molecular species: further development of a rodent model of autism spectrum disorders. Journal of neuroinflammation 9, 153.
Tirsoaga, A., Novikov, A., Adib-Conquy, M., Werts, C., Fitting, C., Cavaillon, J.M. and Caroff, M. (2007). Simple method for repurification of endotoxins for biological use. Applied and environmental microbiology 73, 1803-1808.
Tsai, P.T., Hull, C., Chu, Y., Greene-Colozzi, E., Sadowski, A.R., Leech, J.M., et al. (2012). Autistic-like behaviour and cerebellar dysfunction in Purkinje cell Tsc1 mutant mice. Nature 488, 647-651.
Tuanyok, A., Stone, J.K., Mayo, M., Kaestli, M., Gruendike, J., Georgia, S., et al. (2012). The genetic and molecular basis of O-antigenic diversity in Burkholderia pseudomallei lipopolysaccharide. PLoS neglected tropical diseases 6, e1453.
Turnbaugh, P.J., Backhed, F., Fulton, L. and Gordon, J.I. (2008). Diet-induced obesity is linked to marked but reversible alterations in the mouse distal gut microbiome. Cell Host Microbe 3, 213-223.
Utaisincharoen, P., Tangthawornchaikul, N., Kespichayawattana, W., Anuntagool, N., Chaisuriya, P. and Sirisinha, S. (2000). Kinetic studies of the production of nitric oxide (NO) and tumour necrosis factor-alpha (TNF-alpha) in macrophages stimulated with Burkholderia pseudomallei endotoxin. Clinical and experimental immunology 122, 324-329.
Valentini, V., Piras, G., De Luca, M.A., Perra, V., Bordi, F., Borsini, F., et al. (2013). Evidence for a role of a dopamine/5-HT6 receptor interaction in cocaine reinforcement. Neuropharmacology 65, 58-64.
Vargas, D.L., Nascimbene, C., Krishnan, C., Zimmerman, A.W. and Pardo, C.A. (2005). Neuroglial activation and neuroinflammation in the brain of patients with autism. Ann Neurol 57, 67-81.
Varghese, F., Bukhari, A.B., Malhotra, R. and De, A. (2014). IHC Profiler: an open source plugin for the quantitative evaluation and automated scoring of immunohistochemistry images of human tissue samples. PloS one 9, e96801.
Vasilache, A.M., Kugelberg, U., Blomqvist, A. and Nilsberth, C. (2013). Minor changes in gene expression in the mouse preoptic hypothalamic region by inflammation-induced prostaglandin E2. Journal of neuroendocrinology 25, 635-643.
Vasudeva, R.K., Lin, R.C., Simpson, K.L. and Waterhouse, B.D. (2011). Functional organization of the dorsal raphe efferent system with special consideration of nitrergic cell groups. Journal of chemical neuroanatomy 41, 281-293.
Veenstra-VanderWeele, J., Muller, C.L., Iwamoto, H., Sauer, J.E., Owens, W.A., Shah, C.R., et al. (2012). Autism gene variant causes hyperserotonemia, serotonin receptor hypersensitivity, social impairment and repetitive behavior. Proceedings of the National Academy of Sciences of the United States of America 109, 5469-5474.
Vestal, D.J. and Jeyaratnam, J.A. (2011). The guanylate-binding proteins: emerging insights into the biochemical properties and functions of this family of large interferon-induced guanosine triphosphatase. J Interferon Cytokine Res 31, 89-97.
Voineagu, I. and Yoo, H.J. (2013). Current progress and challenges in the search for autism biomarkers. Disease markers 35, 55-65.
Weehuizen, T.A., Prior, J.L., van der Vaart, T.W., Ngugi, S.A., Nepogodiev, S.A., Field, R.A., et al. (2015). Differential Toll-Like Receptor-Signalling of Burkholderia pseudomallei Lipopolysaccharide in Murine and Human Models. PloS one 10, e0145397.
Wei, H., Alberts, I. and Li, X. (2013). Brain IL-6 and autism. Neuroscience 252, 320-325.
Weingarden, A.R. and Vaughn, B.P. (2017). Intestinal microbiota, fecal microbiota transplantation, and inflammatory bowel disease. Gut Microbes 8, 238-252.
Westin, K., Buchhave, P., Nielsen, H., Minthon, L., Janciauskiene, S. and Hansson, O. (2012). CCL2 is associated with a faster rate of cognitive decline during early stages of Alzheimer''s disease. PloS one 7, e30525.
Wiersinga, W.J., Currie, B.J. and Peacock, S.J. (2012). Melioidosis. The New England journal of medicine 367, 1035-1044.
Wong, H. and Hoeffer, C. (2017). Maternal IL-17A in autism. Exp Neurol.
Woodman, M.E., Worth, R.G. and Wooten, R.M. (2012). Capsule influences the deposition of critical complement C3 levels required for the killing of Burkholderia pseudomallei via NADPH-oxidase induction by human neutrophils. PloS one 7, e52276.
Woods, C.W., Bressler, A.M., LiPuma, J.J., Alexander, B.D., Clements, D.A., Weber, D.J., et al. (2004). Virulence associated with outbreak-related strains of Burkholderia cepacia complex among a cohort of patients with bacteremia. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 38, 1243-1250.
Wu, W.L., Hsiao, E.Y., Yan, Z., Mazmanian, S.K. and Patterson, P.H. (2017). The placental interleukin-6 signaling controls fetal brain development and behavior. Brain, behavior, and immunity 62, 11-23.
Xie, G., Wang, X., Liu, P., Wei, R., Chen, W., Rajani, C., et al. (2016). Distinctly altered gut microbiota in the progression of liver disease. Oncotarget 7, 19355-19366.
Xuan, I.C. and Hampson, D.R. (2014). Gender-dependent effects of maternal immune activation on the behavior of mouse offspring. PloS one 9, e104433.
Yamashita, M. and Nakayama, T. (2008). Progress in allergy signal research on mast cells: regulation of allergic airway inflammation through toll-like receptor 4-mediated modification of mast cell function. J Pharmacol Sci 106, 332-335.
Yan, Q.S. and Yan, S.E. (2001). Activation of 5-HT(1B/1D) receptors in the mesolimbic dopamine system increases dopamine release from the nucleus accumbens: a microdialysis study. European journal of pharmacology 418, 55-64.
Zager, A., Peron, J.P., Mennecier, G., Rodrigues, S.C., Aloia, T.P. and Palermo-Neto, J. (2015). Maternal immune activation in late gestation increases neuroinflammation and aggravates experimental autoimmune encephalomyelitis in the offspring. Brain, behavior, and immunity 43, 159-171.
Zarrindast, M.R. and Khakpai, F. (2015). The Modulatory Role of Dopamine in Anxiety-like Behavior. Archives of Iranian medicine 18, 591-603.
Zughaier, S.M., Ryley, H.C. and Jackson, S.K. (1999). Lipopolysaccharide (LPS) from Burkholderia cepacia is more active than LPS from Pseudomonas aeruginosa and Stenotrophomonas maltophilia in stimulating tumor necrosis factor alpha from human monocytes. Infection and immunity 67, 1505-1507.
Diagnostic and Statistical Manual of Mental Disorders. (5th edition) American Psychiatric Publishing, Arlington, VA (2000)
薛斐丹。氫氧基脂肪酸為生物指標物偵測蒜頭伯克氏菌誘導之皮下發炎反應。2012﹔國立高雄師範大學研究論文。