|
1.Devenish, R.J., Prescott, M. & Rodgers, A.J. The structure and function of mitochondrial F1F0-ATP synthases. Int Rev Cell Mol Biol 267, 1-58 (2008). 2.Jonckheere, A.I., Smeitink, J.A. & Rodenburg, R.J. Mitochondrial ATP synthase: architecture, function and pathology. J Inherit Metab Dis 35, 211-225 (2012). 3.Weber, J. & Senior, A.E. Catalytic mechanism of F1-ATPase. Biochim Biophys Acta 1319, 19-58 (1997). 4.Anderson, S., Bankier, A.T., Barrell, B. G., De Bruijn, M. H. L., Coulson, A. R., Drouin, J., Eperon, I. C., Nierlich, D. P., Roe, B. A., Sanger, F.,. Schreier, P. H, Smith, A. J. H., Staden, R. & Young, I. G. Sequence and organization of the human mitochondrial genome. Nature 290, 457-465 (1981). 5.Martinez, L.O. Jacquet, S., Esteve, J.P., Rolland, C., Cabezón, E., Champagne, E., Pineau, T., Georgeaud, V., Walker, J.E., Tercé, F., Collet, X., Perret, B. & Barbaras, R. Ectopic beta-chain of ATP synthase is an apolipoprotein A-I receptor in hepatic HDL endocytosis. Nature 421, 75-79 (2003). 6.Yavlovich, A., Viard, M., Zhou, M., Veenstra, T.D., Wang, J.M., Gong, W., Heldman, E., Blumenthal, R. & Raviv, Y. Ectopic ATP synthase facilitates transfer of HIV-1 from antigen-presenting cells to CD4(+) target cells. Blood 120, 1246-1253 (2012). 7.Mühleip, A.W., Joos, F., Wigge, C., Frangakis, A.S., Kühlbrandt, W. & Daviesa, K.M. Helical arrays of U-shaped ATP synthase dimers form tubular cristae in ciliate mitochondria. Proc Natl Acad Sci U S A 113, 8442-8447 (2016). 8.Ma, Z. Cao, M., Liu, Y., He, Y., Wang, Y., Yang, C., Wang, W., Du, Y., Zhou, M. & Gao, F. Mitochondrial F1Fo-ATP synthase translocates to cell surface in hepatocytes and has high activity in tumor-like acidic and hypoxic environment. Acta Biochim Biophys Sin (Shanghai) 42, 530-537 (2010). 9.Chang, H.Y., Huang, H.C., Huang, T.C., Yang, P.C., Wang, Y.C. & Juan, H.F. Ectopic ATP synthase blockade suppresses lung adenocarcinoma growth by activating the unfolded protein response. Cancer Res 72, 4696-4706 (2012). 10.Chang, H.Y., Huang, T.C., Chen, N.N., Huang, H.C. & Juan, H.F. Combination therapy targeting ectopic ATP synthase and 26S proteasome induces ER stress in breast cancer cells. Cell Death Dis 5, e1540 (2014). 11.Schmidt, C., Lepsverdize, E., Chi, S.L., Das, A.M., Pizzo, S.V., Dityatev, A. & Schachner, M. Amyloid precursor protein and amyloid beta-peptide bind to ATP synthase and regulate its activity at the surface of neural cells. Mol Psychiatry 13, 953-969 (2008). 12.Wang, T., Chen, Z., Wang, X., Shyy, J.Y. & Zhu, Y. Cholesterol loading increases the translocation of ATP synthase beta chain into membrane caveolae in vascular endothelial cells. Biochim Biophys Acta 1761, 1182-1190 (2006). 13.Rai, A.K., Spolaore, B., Harris, D.A., Dabbeni-Sala, F. & Lippe, G. Ectopic F0F 1 ATP synthase contains both nuclear and mitochondrially-encoded subunits. J Bioenerg Biomembr 45, 569-579 (2013). 14.Walter, P. & Johnson, A.E. Signal sequence recognition and protein targeting to the endoplasmic reticulum membrane. Annu Rev Cell Biol 10, 87-119 (1994). 15.Akopian, D., Shen, K., Zhang, X. & Shan, S.O. Signal recognition particle: an essential protein-targeting machine. Annu Rev Biochem 82, 693-721 (2013). 16.Weihofen, A., Lemberg, M.K., Ploegh, H.L., Bogyo, M. & Martoglio, B. Release of signal peptide fragments into the cytosol requires cleavage in the transmembrane region by a protease activity that is specifically blocked by a novel cysteine protease inhibitor. J Biol Chem 275, 30951-30956 (2000). 17.Sato, K. COPII coat assembly and selective export from the endoplasmic reticulum. J Biochem 136, 755-760 (2004). 18.Woollatt, E., Pine, K.A., Shine, J., Sutherland, G.R. & Iismaa, T.P. Human Sec63 endoplasmic reticulum membrane protein, map position 6q21. Chromosome Res 7, 77 (1999). 19.Neupert, W. Protein import into mitochondria. Annu Rev Biochem 66, 863-917 (1997). 20.Cokol, M., Nair, R. & Rost, B. Finding nuclear localization signals. EMBO Rep 1, 411-415 (2000). 21.Vantourout, P. et al. Ecto-F(1)-ATPase: a moonlighting protein complex and an unexpected apoA-I receptor. World J Gastroenterol 16, 5925-5935 (2010). 22.Gabriel, K., Egan, B. & Lithgow, T. Tom40, the import channel of the mitochondrial outer membrane, plays an active role in sorting imported proteins. EMBO J 22, 2380-2386 (2003). 23.Diekert, K., Kispal, G., Guiard, B. & Lill, R. An internal targeting signal directing proteins into the mitochondrial intermembrane space. Proc Natl Acad Sci U S A 96, 11752-11757 (1999). 24.Omura, T. Mitochondria-targeting sequence, a multi-role sorting sequence recognized at all steps of protein import into mitochondria. J Biochem 123, 1010-1016 (1998). 25.Chacinska, A., Koehler, C.M., Milenkovic, D., Lithgow, T. & Pfanner, N. Importing mitochondrial proteins: machineries and mechanisms. Cell 138, 628-644 (2009). 26.Mishra, P. & Chan, D.C. Metabolic regulation of mitochondrial dynamics. J Cell Biol 212, 379-387 (2016). 27.Wai, T. & Langer, T. Mitochondrial Dynamics and Metabolic Regulation. Trends Endocrinol Metab 27, 105-117 (2016). 28.Chan, D.C. Mitochondrial fusion and fission in mammals. Annu Rev Cell Dev Biol 22, 79-99 (2006). 29.Amiott, E.A., Lott, P., Soto, J., Kang, P.B., McCaffery, J.M., DiMauro, S., Abel, E.D., Flanigan, K.M., Lawson, V.H. & Shaw, J.M. Mitochondrial fusion and function in Charcot-Marie-Tooth type 2A patient fibroblasts with mitofusin 2 mutations. Exp Neurol 211, 115-127 (2008). 30.Archer, S.L. Mitochondrial dynamics--mitochondrial fission and fusion in human diseases. N Engl J Med 369, 2236-2251 (2013). 31.van der Bliek, A.M., Shen, Q. & Kawajiri, S. Mechanisms of mitochondrial fission and fusion. Cold Spring Harb Perspect Biol 5 (2013). 32.Wikstrom, J.D., Mahdaviani, K., Liesa, M., Sereda, S.B., Si, Y., Las, G., Twig, G., Petrovic, N., Zingaretti, C., Graham, A., Cinti, S., Corkey, B.E., Cannon, B., Nedergaard, J. & Shirihai, O.S. Hormone-induced mitochondrial fission is utilized by brown adipocytes as an amplification pathway for energy expenditure. EMBO J 33, 418-436 (2014). 33.Youle, R.J. & van der Bliek, A.M. Mitochondrial fission, fusion, and stress. Science 337, 1062-1065 (2012). 34.Hoppins, S., Lackner, L. & Nunnari, J. The machines that divide and fuse mitochondria. Annu Rev Biochem 76, 751-780 (2007). 35.Eisner, V., Lenaers, G. & Hajnoczky, G. Mitochondrial fusion is frequent in skeletal muscle and supports excitation-contraction coupling. J Cell Biol 205, 179-195 (2014). 36.Mishra, P. & Chan, D.C. Mitochondrial dynamics and inheritance during cell division, development and disease. Nat Rev Mol Cell Biol 15, 634-646 (2014). 37.Labbe, K., Murley, A. & Nunnari, J. Determinants and functions of mitochondrial behavior. Annu Rev Cell Dev Biol 30, 357-391 (2014). 38.Gomes, L.C., Di Benedetto, G. & Scorrano, L. During autophagy mitochondria elongate, are spared from degradation and sustain cell viability. Nat Cell Biol 13, 589-598 (2011). 39.Frank, S., Gaume, B., Bergmann-Leitner, E.S., Leitner, W.W., Robert, E.G., Catez, F., Smith, C.L. & Youle, R.J. The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis. Dev Cell 1, 515-525 (2001). 40.Sheng, Z.H. & Cai, Q. Mitochondrial transport in neurons: impact on synaptic homeostasis and neurodegeneration. Nat Rev Neurosci 13, 77-93 (2012). 41.Caino, M.C., Seo, J.H., Aguinaldo, A., Wait, E., Bryant, K.G., Kossenkov, A.V., Hayden, J.E., Vaira, V., Morotti, A., Ferrero, S., Bosari, S., Gabrilovich, D.I., Languino, L.R., Cohen, A.R. & Altieri, D.C.A neuronal network of mitochondrial dynamics regulates metastasis. Nat Commun 7, 13730 (2016). 42.Chen, Y. & Sheng, Z.H. Kinesin-1-syntaphilin coupling mediates activity-dependent regulation of axonal mitochondrial transport. J Cell Biol 202, 351-364 (2013). 43.Mo, R.H., Zaro, J.L., Ou, J.H. & Shen, W.C. Effects of Lipofectamine 2000/siRNA complexes on autophagy in hepatoma cells. Mol Biotechnol 51, 1-8 (2012). 44.Cox, J. & Mann, M. MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification. Nat Biotechnol 26, 1367-1372 (2008). 45.de Chaumont, F., Dallongeville, S., Chenouard, N., Hervé, N., Pop, S., Provoost, T., Meas-Yedid, V., Pankajakshan, P., Lecomte, T., Le Montagner, Y., Lagache, T., Dufour, A. & Olivo-Marin, J.C. Icy: an open bioimage informatics platform for extended reproducible research. Nat Methods 9, 690-696 (2012). 46.Pagliuso, A., Tham, T.N., Stevens, J.K., Lagache, T., Persson, R., Salles, A., Olivo-Marin, J.C., Oddos, S., Spang, A., Cossart, P. & Stavru, F. A role for septin 2 in Drp1-mediated mitochondrial fission. EMBO Rep 17, 858-873 (2016). 47.Mitra, K. & Lippincott-Schwartz, J. Analysis of mitochondrial dynamics and functions using imaging approaches. Curr Protoc Cell Biol Chapter 4, Unit 4 25 21-21 (2010). 48.De Vos, K.J. & Sheetz, M.P. Visualization and Quantification of Mitochondrial Dynamics in Living Animal Cells. 80, 627-682 (2007). 49.Hsu, C.L., Chang, H.Y., Chang, J.Y., Hsu, W.M., Huang, H.C. & Juan, H.F.. Unveiling MYCN regulatory networks in neuroblastoma via integrative analysis of heterogeneous genomics data. Oncotarget 7, 36293-36310 (2016). 50.Blackstone, C. & Chang, C.R. Mitochondria unite to survive. Nat Cell Biol 13, 521-522 (2011). 51.Solaini, G., Sgarbi, G. & Baracca, A. Oxidative phosphorylation in cancer cells. Biochim Biophys Acta 1807, 534-542 (2011). 52.Buchet, K. & Godinot, C. Functional F1-ATPase essential in maintaining growth and membrane potential of human mitochondrial DNA-depleted rho degrees cells. J Biol Chem 273, 22983-22989 (1998). 53.Simonnet, H., Alazard, N., Pfeiffer, K., Gallou, C., Béroud, C., Demont, J., Bouvier, R., Schägger, H. & Godinot, C. Low mitochondrial respiratory chain content correlates with tumor aggressiveness in renal cell carcinoma. Carcinogenesis 23, 759-768 (2002). 54.Cuezva, J.M., Sanchez-Arago, M., Sala, S., Blanco-Rivero, A. & Ortega, A.D. A message emerging from development: the repression of mitochondrial beta-F1-ATPase expression in cancer. J Bioenerg Biomembr 39, 259-265 (2007). 55.Cuezva, J.M., Krajewska, M., de Heredia, M.L., Krajewski, S., Santamaría, G., Kim, H., Zapata, J.M., Marusawa, H., Chamorro, M. & Reed, J.C. The bioenergetic signature of cancer: a marker of tumor progression. Cancer Res 62, 6674-6681 (2002). 56.Hao, W., Chang, C.P., Tsao, C.C. & Xu, J. Oligomycin-induced bioenergetic adaptation in cancer cells with heterogeneous bioenergetic organization. J Biol Chem 285, 12647-12654 (2010). 57.Xing, S.L., Yan, J., Yu, Z.H. & Zhu, C.Q. Neuronal cell surface ATP synthase mediates synthesis of extracellular ATP and regulation of intracellular pH. Cell Biol Int 35, 81-86 (2011). 58.Arakaki, N., Nagao, T., Niki, R., Toyofuku, A., Tanaka, H., Kuramoto, Y., Emoto, Y., Shibata, H., Magota, K. & Higuti, T. Possible role of cell surface H+ -ATP synthase in the extracellular ATP synthesis and proliferation of human umbilical vein endothelial cells. Mol Cancer Res 1, 931-939 (2003). 59.Dowling, P., Meleady, P., Dowd, A., Henry, M., Glynn, S. & Clynes, M. Proteomic analysis of isolated membrane fractions from superinvasive cancer cells. Biochim Biophys Acta 1774, 93-101 (2007). 60.Lu, Z.J., Song, Q.F., Jiang, S.S., Song, Q., Wang, W., Zhang, G.H., Kan, B., Chen, L.J., Yang, J.L., Luo, F., Qian, Z.Y., Wei, Y.Q. & Gou, L.T. Identification of ATP synthase beta subunit (ATPB) on the cell surface as a non-small cell lung cancer (NSCLC) associated antigen. BMC Cancer 9, 16 (2009). 61.Vyas, S., Zaganjor, E. & Haigis, M.C. Mitochondria and Cancer. Cell 166, 555-566 (2016). 62.Senft, D. & Ronai, Z.A. Regulators of mitochondrial dynamics in cancer. Curr Opin Cell Biol 39, 43-52 (2016). 63.Rossignol, R., Gilkerson, R., Aggeler, R., Yamagata, K., Remington, S.J., Capaldi & R.A. Energy substrate modulates mitochondrial structure and oxidative capacity in cancer cells. Cancer Res 64, 985-993 (2004). 64.Serasinghe, M.N., Wieder, S.Y., Renault, T.T., Elkholi, R., Asciolla, J.J., Yao, J.L., Jabado, O., Hoehn, K., Kageyama, Y., Sesaki, H., Chipuk & J.E. Mitochondrial division is requisite to RAS-induced transformation and targeted by oncogenic MAPK pathway inhibitors. Mol Cell 57, 521-536 (2015). 65.Hagenbuchner, J., Kuznetsov, A.V., Obexer, P. & Ausserlechner, M.J. BIRC5/Survivin enhances aerobic glycolysis and drug resistance by altered regulation of the mitochondrial fusion/fission machinery. Oncogene 32, 4748-4757 (2013). 66.Mironov, S.L. ADP regulates movements of mitochondria in neurons. Biophys J 92, 2944-2952 (2007). 67.Desai, S.P., Bhatia, S.N., Toner, M. & Irimia, D. Mitochondrial localization and the persistent migration of epithelial cancer cells. Biophys J 104, 2077-2088 (2013). 68.Mancias, J.D. & Kimmelman, A.C. Mechanisms of Selective Autophagy in Normal Physiology and Cancer. J Mol Biol 428, 1659-1680 (2016). 69.Hu, Y.L., DeLay, M., Jahangiri, A., Molinaro, A.M., Rose, S.D., Carbonell, W.S., & Aghi, M.K. Hypoxia-induced autophagy promotes tumor cell survival and adaptation to antiangiogenic treatment in glioblastoma. Cancer Res 72, 1773-1783 (2012). 70.Buhlman, L., Damiano, M., Bertolin, G., Ferrando-Miguel, R., Lombès, A., Brice, A. & Corti, O.. Functional interplay between Parkin and Drp1 in mitochondrial fission and clearance. Biochim Biophys Acta 1843, 2012-2026 (2014). 71.Korobova, F., Ramabhadran, V. & Higgs, H.N. An actin-dependent step in mitochondrial fission mediated by the ER-associated formin INF2. Science 339, 464-467 (2013). 72.Phillips, M.J. & Voeltz, G.K. Structure and function of ER membrane contact sites with other organelles. Nat Rev Mol Cell Biol 17, 69-82 (2016). 73.Gumbleton, M., Abulrob, A.G. & Campbell, L. Caveolae: an alternative membrane transport compartment. Pharm Res 17, 1035-1048 (2000). 74.Smart, E.J., Ying, Y., Donzell, W.C. & Anderson, R.G. A role for caveolin in transport of cholesterol from endoplasmic reticulum to plasma membrane. J Biol Chem 271, 29427-29435 (1996). 75.Raturi, A. & Simmen, T. Where the endoplasmic reticulum and the mitochondrion tie the knot: the mitochondria-associated membrane (MAM). Biochim Biophys Acta 1833, 213-224 (2013). 76.Rambold, A.S., Kostelecky, B., Elia, N. & Lippincott-Schwartz, J. Tubular network formation protects mitochondria from autophagosomal degradation during nutrient starvation. Proc Natl Acad Sci U S A 108, 10190-10195 (2011). 77.Tangmansakulchai, K., Abubakar, Z., Kitiyanant, N., Suwanjang, W., Leepiyasakulchai, C., Govitrapong, P. & Chetsawang, B. Calpastatin overexpression reduces oxidative stress-induced mitochondrial impairment and cell death in human neuroblastoma SH-SY5Y cells by decreasing calpain and calcineurin activation, induction of mitochondrial fission and destruction of mitochondrial fusion. Mitochondrion 30, 151-161 (2016). 78.Wang, K., Yan, R., Cooper, K.F. & Strich, R. Cyclin C mediates stress-induced mitochondrial fission and apoptosis. Mol Biol Cell 26, 1030-1043 (2015). 79.Graves, J.A., Wang, Y., Sims-Lucas, S., Cherok, E., Rothermund, K., Branca, M.F., Elster, J., Beer-Stolz, D., Van Houten, B., Vockley, J. & Prochownik, E.V. Mitochondrial structure, function and dynamics are temporally controlled by c-Myc. PLoS One 7, e37699 (2012). 80.Sancho, P., Burgos-Ramos, E., Tavera, A., Bou Kheir, T., Jagust, P., Schoenhals, M., Barneda, D., Sellers, K., Campos-Olivas, R., Graña, O., Viera, C.R., Yuneva M., Sainz, B. Jr. & Heeschen, C. MYC/PGC-1alpha Balance Determines the Metabolic Phenotype and Plasticity of Pancreatic Cancer Stem Cells. Cell Metab 22, 590-605 (2015). 81.Sarin, M.,Wang, Y., Zhang, F., Rothermund, K., Zhang, Y., Lu, J., Sims-Lucas, S., Beer-Stolz, D., Van Houten, B.E., Vockley, J., Goetzman, E.S., Graves, J.A. & Prochownik, E.V. Alterations in c-Myc phenotypes resulting from dynamin-related protein 1 (Drp1)-mediated mitochondrial fission. Cell Death Dis 4, e670 (2013). 82.Westermann, F., Muth, D., Benner, A., Bauer, T., Henrich, K.O., Oberthuer, A., Brors, B., Beissbarth, T., Vandesompele, J., Pattyn, F., Hero, B., König, R., Fischer, M. & Schwab, M. Distinct transcriptional MYCN/c-MYC activities are associated with spontaneous regression or malignant progression in neuroblastomas. Genome Biol 9, R150 (2008). 83.Huang, M. & Weiss, W.A. Neuroblastoma and MYCN. Cold Spring Harb Perspect Med 3, a014415 (2013). 84.Brodeur, G.M. Neuroblastoma: biological insights into a clinical enigma. Nat Rev Cancer 3, 203-216 (2003). 85.Fields, W.R., Desiderio, J.G., Putnam, K.P., Bombick, D.W. & Doolittle, D.J. Quantification of changes in c-myc mRNA levels in normal human bronchial epithelial (NHBE) and lung adenocarcinoma (A549) cells following chemical treatment. Toxicol Sci 63, 107-114 (2001). 86.Vander Heiden, M.G., Cantley, L.C. & Thompson, C.B. Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science 324, 1029-1033 (2009). 87.Fish, K.N. Total internal reflection fluorescence (TIRF) microscopy. Curr Protoc Cytom Chapter 12, Unit12 18 (2009).
|