|
Ahn, J. Y.; Schwarz, J. K.; Piwnica-Worms, H.; Canman, C. E. Threonine 68 phosphorylation by ataxia telangiectasia mutated is required for efficient activation of Chk2 in response to ionizing radiation. Cancer Res. 2000, 60(21), 5934-5936. Aibe, T.; Fuji, T.; Okita, K.; Takemoto, T. . A fundamental study of normal layer structure of the gastrointestinal wall visualized by endoscopic ultrasonography. Scand. J. Gastroenterol. 1986, 21(sup123), 6-15. Amadori, A.; Belardelli, F.; Cavallo, F.; Ferraris, P.; Derossi, A.; Doria, G.; Jemma, C. (1992). Mind the mouse-a consensus view on the use of immunodeficient mice in immunology and oncology: pensiero scientifico editor via bradano 3/c, 00199 Rome, Italy. Anand, P.; Kunnumakkara, A. B.; Newman, R. A.; Aggarwal, B. B. Bioavailability of curcumin: problems and promises. Mol. Pharm. 2007, 4(6), 807-818. Assoian, R. K.; Zhu, X. Cell anchorage and the cytoskeleton as partners in growth factor dependent cell cycle progression. Curr. Opin. Cell Biol. 1997, 9(1), 93-98. Awwad, R. A.; Sergina, N.; Yang, H.; Ziober, B.; Willson, J. K.; Zborowska, E.; Humphrey, L. E.; Fan, R.; Ko, T. C.; Brattain, M. G.; Howell, G. M. The role of transforming growth factor α in determining growth factor independence. Cancer Res. 2003, 63(15), 4731-4738. Bardou, M.; Montembault, S.; Giraud, V.; Balian, A.; Borotto, E.; Houdayer, C.; Capron, F.; Chaput, J. C.; Naveau, S. Excessive alcohol consumption favours high risk polyp or colorectal cancer occurrence among patients with adenomas: a case control study. Gut 2002, 50(1), 38-42. Bartek, J.; Lukas, J. Chk1 and Chk2 kinases in checkpoint control and cancer. Cancer cell 2003, 3(5), 421-429. Beija, M.; Salvayre, R.; Lauth-de Viguerie, N.; Marty, J. D. Colloidal systems for drug delivery: from design to therapy. Trends Biotechnol. 2012, 30(9), 485-496. Bentley, R.; Meganathan, R. Biosynthesis of vitamin K (menaquinone) in bacteria. Microbiol. Rev. 1982, 46(3), 241. Bibby, M. C. Orthotopic models of cancer for preclinical drug evaluation: advantages and disadvantages. Eur. J. Cancer 2004, 40(6), 852-857. Board, P. A. T. E. (2016). Colon Cancer Treatment (PDQ®). Brattain, M. G.; Fine, W. D.; Khaled, F. M.; Thompson, J.; Brattain, D. E. Heterogeneity of malignant cells from a human colonic carcinoma. Cancer Res. 1981, 41(5), 1751-1756. Bunz, F.; Dutriaux, A.; Lengauer, C.; Waldman, T.; Zhou, S.; Brown, J.; Sedivy, J. M.; Kinzler, K. W.; Vogelstein, B. Requirement for p53 and p21 to sustain G2 arrest after DNA damage. Science 1998, 282(5393), 1497-1501. Canman, C. E.; Lim, D. S.; Cimprich, K. A.; Taya, Y.; Tamai, K.; Sakaguchi, K.; Appella, E.; Kastan, M. B.; Siliciano, J. D. Activation of the ATM kinase by ionizing radiation and phosphorylation of p53. Science 1998, 281(5383), 1677-1679. Chan, D. S.; Lau, R.; Aune, D.; Vieira, R.; Greenwood, D. C.; Kampman, E.; Norat, T. Red and processed meat and colorectal cancer incidence: meta-analysis of prospective studies. PloS One 2011, 6(6), e20456. Chao, A.; Thun, M. J.; Jacobs, E. J.; Henley, S. J.; Rodriguez, C.; Calle, E. E. Cigarette smoking and colorectal cancer mortality in the cancer prevention study II. J. Natl. Cancer Inst. 2000, 92(23), 1888-1896. Charman, S. A.; Charman, W. N.; Rogge, M. C.; Wilson, T. D.; Dutko, F. J.; Pouton, C. W. Self-emulsifying drug delivery systems: formulation and biopharmaceutic evaluation of an investigational lipophilic compound. Pharm. Res. 1992, 9(1), 87-93. Chaudhary, A.; Nagaich, U.; Gulati, N.; Sharma, V.; Khosa, R.; Partapur, M. U. Enhancement of solubilization and bioavailability of poorly soluble drugs by physical and chemical modifications: A recent review. J. Adv. Pharm. Educ. Res. 2012, 2(1), 32-67. Chen, L. Comparison of inhibitive effects of Curcumin and Calebin-A on human hepatoma cell line HepG2. 第四軍醫大學學報 2009, 30(1), 7-10. Clarke, R.; Dickson, R. Animal models of tumor onset, growth, and metastasis. Ency. Cancer 1998, 1, 10-21. Constantinides, P. P. Lipid Microemulsions for Improving Drug Dissolution and Oral Absorption: Physical and Biopharmaceutical Aspects. AAPS J. 1995, 12(11), 1561-1572. Constantinides, P. P. Lipid microemulsions for improving drug dissolution and oral absorption: physical and biopharmaceutical aspects. Pharm. Res. 1995, 12(11), 1561-1572. Craig, D.; Barker, S.; Banning, D.; Booth, S. An investigation into the mechanisms of self-emulsification using particle size analysis and low frequency dielectric spectroscopy. Int. J. Pharm. 1995, 114(1), 103-110. Craig, D.; Lievens, H.; Pitt, K.; Storey, D. An investigation into the physico-chemical properties of self-emulsifying systems using low frequency dielectric spectroscopy, surface tension measurements and particle size analysis. Int. J. Pharm. 1993, 96(1-3), 147-155. Cui, J.; Yu, B.; Zhao, Y.; Zhu, W.; Li, H.; Lou, H.; Zhai, G. Enhancement of oral absorption of curcumin by self-microemulsifying drug delivery systems. Int. J. Pharm. 2009, 371(1), 148-155. Dabros, T.; Yeung, A.; Masliyah, J.; Czarnecki, J. Emulsification through area contraction. J. Colloid Interface Sci. 1999, 210(1), 222-224. De Souza, C. P. C.; Ellem, K. A. O.; Gabrielli, B. G. Centrosomal and cytoplasmic Cdc2/Cyclin B1 activation precedes nuclear mitotic events. Exp. Cell Res. 2000, 257(1), 11-21. Deng, Y.; Shipps Jr, G. W.; Zhao, L.; Siddiqui, M. A.; Popovici-Muller, J.; Curran, P. J.; Duca, J. S.; Hruza, A. W.; Fischmann, T. O.; Madison, V. S.; Zhang, R.; McNemae, C. W.; Mayhood, T. W.; Syto, R.; Annis, A.; Kirshmeier, P.; Lees, E. M.; Parry, D. A; Windsor, W. T. Modulating the interaction between CDK2 and cyclin A with a quinoline-based inhibitor. Bioorg. Med. Chem. Lett. 2014, 24(1), 199-203. Dixit, A. R.; Rajput, S. J.; Patel, S. G. Preparation and bioavailability assessment of SMEDDS containing valsartan. AAPS Pharm. Sci. Tech. 2010, 11(1), 314-321. Drasar, B. S.; Hill, M. J. (1974). Human intestinal flora: Academic Press (London) Ltd., 24/28 Oval Road, London, NWI. Dufour, D. R.; Lott, J. A.; Nolte, F. S.; Gretch, D. R.; Koff, R. S.; Seeff, L. B. Diagnosis and monitoring of hepatic injury. II. Recommendations for use of laboratory tests in screening, diagnosis, and monitoring. Clin. Chem. 2000, 46(12), 2050-2068. Dukes, C. E. The classification of cancer of the rectum. J. Pathol. Bacteriol. 1932, 35(3), 323-332. Ehrig, K.; Kilinc, M. O.; Chen, N. G.; Stritzker, J.; Buckel, L.; Zhang, Q.; Szalay, A. A. Growth inhibition of different human colorectal cancer xenografts after a single intravenous injection of oncolytic vaccinia virus GLV-1h68. J. Transl. Med. 2013, 11(1), 79. Evans, T.; Rosenthal, E. T.; Youngblom, J.; Distel, D.; Hunt, T. Cyclin: A protein specified by maternal mRNA in sea urchin eggs that is destroyed at each cleavage division. Cell 1983, 33(2), 389-396. Fiebig, H.; Berger, D. Preclinical phase II trials. The nude mouse in oncology research. CRC Press Boca Raton 1995, 318-335. Florence, A. T.; Hussain, N. Transcytosis of nanoparticle and dendrimer delivery systems: evolving vistas. Adv. Drug Deliv. Rev. 2001, 50, S69-S89. Fuster, J. J.; Fernández, P.; González-Navarro, H.,;Silvestre, C.; Nabah, Y. N. A.; Andrés, V. Control of cell proliferation in atherosclerosis: insights from animal models and human studies. Cardiovasc. Res. 2010, 86(2), 254-264. Gershanik, T.; Benita, S. Self-dispersing lipid formulations for improving oral absorption of lipophilic drugs. Eur. J. Pharm. Biopharm. 2000, 50(1), 179-188. Giavazzi, R.; Campbell, D. E.; Jessup, J.; Cleary, K.; Fidler, I. J. Metastatic behavior of tumor cells isolated from primary and metastatic human colorectal carcinomas implanted into different sites in nude mice. Cancer Res. 1986, 46(4 Part 2), 1928-1933. Giovannucci, E.; Ascherio, A.; Rimm, E. B.; Colditz, G. A.; Stampfer, M. J.; Willett, W. C. Physical activity, obesity, and risk for colon cancer and adenoma in men. Ann. Intern. Med. 1995, 122(5), 327-334. Girard, F.; Strausfeld, U.; Fernandez, A.; Lamb, N. J. Cyclin A is required for the onset of DNA replication in mammalian fibroblasts. Cell 1991, 67(6), 1169-1179. Glotzer, M.; Murray, A. W.; Kirschner, M. W. Cyclin is degraded by the ubiquitin pathway. Nature 1991, 349(6305), 132-138. González-Castejón, M.; Rodriguez-Casado, A. Dietary phytochemicals and their potential effects on obesity: a review. Pharmacol. Res. 2011, 64(5), 438-455. Hartwell, L. H.; Kastan, M. B. Cell cycle control and cancer. Science 1994, 266(5192), 1821. Hauss, D. J.; Fogal, S. E.; Ficorilli, J. V.; Price, C. A.; Roy, T.; Jayaraj, A. A.; Keirns, J. J. Lipid‐based delivery systems for improving the bioavailability and lymphatic transport of a poorly water‐soluble LTB4 inhibitor. J. Pharm. Sci. 1998, 87(2), 164-169. Health, N. I. o. Biological Sciences Curriculum Study. NIH curriculum supplement series [Internet]. Bethesda (MD): National Institutes of Health (US); 2007. Understanding Emerging and Re-emerging Infectious Diseases. Hirao, A.; Kong, Y.Y.; Matsuoka, S.; Wakeham, A.; Ruland, J.; Yoshida, H.;Liu, D.; Elledge, S. L.; Mak, T. W. DNA damage-induced activation of p53 by the checkpoint kinase Chk2. Science 2000, 287(5459), 1824. Ireson, C.; Orr, S.; Jones, D. J.; Verschoyle, R.; Lim, C. K.; Luo, J. L.; Howell, L.; Plummer, S; Williams, M.; Steward, W. P.; Gescher, A. Characterization of metabolites of the chemopreventive agent curcumin in human and rat hepatocytes and in the rat in vivo, and evaluation of their ability to inhibit phorbol ester-induced prostaglandin E2 production. Cancer Res. 2001, 61(3), 1058-1064. Ireson, C. R.; Jones, D. J.; Orr, S.; Coughtrie, M. W.; Boocock, D. J.; Williams, M. L.; Farmer, P. B.; Steward, W. P.; Gescher, A. J. Metabolism of the cancer chemopreventive agent curcumin in human and rat intestine. Cancer Epidemiol. Biomarkers Prev. 2002, 11(1), 105-111. Janković, J.; Djekic, L.; Dobričić, V.; Primorac, M. Evaluation of critical formulation parameters in design and differentiation of self-microemulsifying drug delivery systems (SMEDDSs) for oral delivery of aciclovir. Int. J. Pharm. 2016, 497(1), 301-311. Jinno, S.; Suto, K.; Nagata, A.; Igarashi, M.; Kanaoka, Y.; Nojima, H.; Okayama, H. Cdc25A is a novel phosphatase functioning early in the cell cycle. EMBO J. 1994, 13(7), 1549. Jordan, B. C.; Mock, C. D.; Thilagavathi, R.; Selvam, C. Molecular mechanisms of curcumin and its semisynthetic analogues in prostate cancer prevention and treatment. Life Sci. 2016, 152, 135-144. Kamboj, S.; Rana, V. Quality-by-design based development of a self-microemulsifying drug delivery system to reduce the effect of food on Nelfinavir mesylate. Int.l J.l Pharm. 2016, 501(1), 311-325. Kang, B. K.; Lee, J. S.; Chon, S. K.; Jeong, S. Y.; Yuk, S. H.; Khang, G.; Lee, H. B.; Cho, S. H. Development of self-microemulsifying drug delivery systems (SMEDDS) for oral bioavailability enhancement of simvastatin in beagle dogs. International Journal of Pharmaceutics 2004, 274(1–2), 65-73. Kawamori, T.; Lubet, R.; Steele, V. E.; Kelloff, G. J.; Kaskey, R. B.; Rao, C. V.; Reddy, B. S. Chemopreventive effect of curcumin, a naturally occurring anti-inflammatory agent, during the promotion/progression stages of colon cancer. Cancer Res. 1999, 59(3), 597-601. Kim, D. S.; Kim, J. Y. Total synthesis of calebin-A, preparation of its analogues, and their neuronal cell protectivity against β-amyloid insult. Bioorg. Med. Chem. Lett. 2001, 11, 2541-2543. Kimura, M.; Shizuki, M.; Miyoshi, K.; Sasai, T.; Hidaka, H.; Tatakamura, H.; Matoba, T. Relationship between the molecular structures and emulsification properties of edible oils. Biosci. Biotechnol. Biochem. 1994, 58(7), 1258-1261. King, R. W.; Jackson, P. K.; Kirschner, M. W. Mitosis in transition. Cell 1994, 79(4), 563-571. Kohli, K.; Chopra, S.; Dhar, D.; Arora, S.; Khar, R. K. Self-emulsifying drug delivery systems: an approach to enhance oral bioavailability. Drug Discov. Today 2010, 15(21–22), 958-965. Kumar, A.; Ahuja, A.; Ali, J.; Baboota, S. Curcumin-loaded lipid nanocarrier for improving bioavailability, stability and cytotoxicity against malignant glioma cells. Drug Deliv. 2016, 23(1), 214-229. Lai, C. S.; Liao, S. N.; Tsai, M. L.; Kalyanam, N.; Majeed, M.; Majeed, A.; Ho, C. T.; Pan, M. H. Calebin-A inhibits adipogenesis and hepatic steatosis in high-fat diet-induced obesity via activation of AMPK signaling. Mol. Nutr. Food Res. 2015, 59(10), 1883-1895. Lampe, J. W.; Chang, J. L. (2007) Interindividual differences in phytochemical metabolism and disposition. Paper presented at the Seminars in cancer biology. Li, Y.; Jenkins, C. W.; Nichols, M. A.; Xiong, Y. Cell cycle expression and p53 regulation of the cyclin-dependent kinase inhibitor p21. Oncogene 1994, 9(8), 2261-2268. Li, Y.; Li, S.; Han, Y.; Liu, J.; Zhang, J.; Li, F.; Wang, Y.; Liu, X.; Yao, L. Calebin-A induces apoptosis and modulates MAPK family activity in drug resistant human gastric cancer cells. Eur. J. Pharmacol. 2008, 591(1-3), 252-258. Li, Y.; McClements, D. J. New mathematical model for interpreting pH-stat digestion profiles: Impact of lipid droplet characteristics on in vitro digestibility. J. Agric. Food Chem. 2010, 58(13), 8085-8092. Liang, P. S.; Chen, T. Y.; Giovannucci, E. Cigarette smoking and colorectal cancer incidence and mortality: Systematic review and meta‐analysis. Int. J. Cancer 2009, 124(10), 2406-2415. Liou, W. S.; Lin, C.; Lee, P. S.; Kalyanam, N.; Ho, C. T.; Pan, M. H. Calebin-A induces cell cycle arrest in human colon cancer cells and xenografts in nude mice. J. Funct. Foods 2016, 26, 781-791. Liu, W.; Tian, R.; Hu, W.; Jia, Y.; Jiang, H.; Zhang, J.; Zhang, L. Preparation and evaluation of self-microemulsifying drug delivery system of baicalein. Fitoterapia 2012, 83(8), 1532-1539. Lu, J. L.; Wang, J. C.; Zhao, S. X.; Liu, X. Y.; Zhao, H.; Zhang, X.; Zhou, S. F.; Zhang, Q. Self-microemulsifying drug delivery system (SMEDDS) improves anticancer effect of oral 9-nitrocamptothecin on human cancer xenografts in nude mice. Eur. J. Pharm. Biopharm. 2008, 69(3), 899-907. Ma, Y.; Yang, Y.; Wang, F.; Zhang, P.; Shi, C.; Zou, Y.; Qin, H. Obesity and risk of colorectal cancer: a systematic review of prospective studies. PloS One 2013, 8(1), e53916. Macfarlane, G. T.; Cummings, J. (1991). The colonic flora, fermentation, and large bowel digestive function (Vol. 51): Raven Press, New York. Majeed, M.; Nagabhushanam, K.; Natarajan, S.; Bani, S.; Pandey, A.; Karri, S. K. Investigation of repeated dose (90 day) oral toxicity, reproductive/developmental toxicity and mutagenic potential of ‘Calebin A’. Toxicol. Rep. 2015, 2, 580-589. Malik, M. A.; Wani, M. Y.; Hashim, M. A. Microemulsion method: a novel route to synthesize organic and inorganic nanomaterials: 1st nano update. Arabian J. Chem. 2012, 5(4), 397-417. Marian, B. Colorectal cancer: modeling causes, prevention and therapy. Drug Discov. Today: Dis. Models 2004, 1(1), 1-7. Meinzer, A. Microemulsion-A suitable galenical approach for the absorption enhancement of poorly soluble compounds. Bulletin Technique-Gattefosse 1995, 21-26. Moghaddam, A. A.; Woodward, M.; Huxley, R. Obesity and risk of colorectal cancer: a meta-analysis of 31 studies with 70,000 events. Cancer Epidemiol. Biomarkers Prev. 2007, 16(12), 2533-2547. Mosmann, T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods 1983, 65(1-2), 55-63. Navarro, A.; Muñoz, S. E.; Lantieri, M. J.; del Pilar Diaz, M.; Cristaldo, P. E.; de Fabro, S. P.; Eynard, A. R. Meat cooking habits and risk of colorectal cancer in Cordoba, Argentina. Nutrition 2004, 20(10), 873-877. Ohtsubo, M.; Theodoras, A. M.; Schumacher, J.; Roberts, J. M.; Pagano, M. Human cyclin E, a nuclear protein essential for the G1-to-S phase transition. Mol. Cellul. Biol. 1995, 15(5), 2612-2624. Oser, B. L.; Oser, M. Nutritional studies on rats on diets containing high levels of partial ester emulsifiers. 2. Reproduction and lactation. J. Nutr. 1956, 60, 489-505. Ou, Y. H.; Chung, P. H.; Sun, T. P.; Shieh, S. Y. p53 C-terminal phosphorylation by CHK1 and CHK2 participates in the regulation of DNA-damage-induced C-terminal acetylation. Mol. Biol. Cell 2005, 16(4), 1684-1695. Pan, M. H.; Lin-Shiau, S. Y.; Lin, J. K. Comparative studies on the suppression of nitric oxide synthase by curcumin and its hydrogenated metabolites through down-regulation of IκB kinase and NFκB activation in macrophages. Biochem. Pharmacol. 2000, 60(11), 1665-1676. Pan, M. H.; Lai, C. S.; Wu, J. C.; Ho, C. T. Molecular mechanisms for chemoprevention of colorectal cancer by natural dietary compounds. Mol. Nutr. Food Res. 2011, 55(1), 32-45. Pereira, L.; Mariadason, J. M.; Hannan, R. D.; Dhillon, A. S. Implications of epithelial-mesenchymal plasticity for heterogeneity in colorectal cancer. Front. Oncol. 2015, 5, 13. Pines, J. Cyclins: wheels within wheels. Cell Growth Diff. 1991, 2(6), 305-310. Porter, C. J. H.; Pouton, C. W.; Cuine, J. F.; Charman, W. N. Enhancing intestinal drug solubilisation using lipid-based delivery systems. Adv. Drug Deliv. Rev. 2008, 60(6), 673-691. Pouton, C. W. Lipid formulations for oral administration of drugs: non-emulsifying, self-emulsifying and ‘self-microemulsifying’ drug delivery systems. Eur. J. Pharm. Sci. 2000, 11, Supplement 2, S93-S98. Prince, L. (2012). Microemulsions theory and practice: Elsevier. Rajput, A.; Dominguez San Martin, I.; Rose, R.; Beko, A.; LeVea, C.; Sharratt, E.; Mazurchuk, R.; Hoffman, R. M.; Brattain, M. G.; Wang, J. Characterization of HCT116 human colon cancer cells in an orthotopic model. J. Surg. Res. 2008, 147(2), 276-281. Rang, M. J.; Miller, C. A. Spontaneous emulsification of oils containing hydrocarbon, nonionic surfactant, and oleyl alcohol. J. Colloid Interface Sci. 1999, 209(1), 179-192. Reiss, H. Entropy-induced dispersion of bulk liquids. J. Colloid Interface Sci. 1975, 53(1), 61-70. Robertis, M.; Massi, E.; Poeta, M.; Carotti, S.; Morini, S.; Cecchetelli, L.; Signori, E.; Fazio, V. The AOM/DSS murine model for the study of colon carcinogenesis: From pathways to diagnosis and therapy studies. J. Carcinog. 2011, 10(1), 9-9. Sancar, A.; Lindsey-Boltz, L. A.; Ünsal-Kaçmaz, K.; Linn, S. Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints. Ann. Rev. Biochem. 2004, 73(1), 39-85. Sawhney, R. S.; Zhou, G. H. K.; Humphrey, L. E.; Ghosh, P.; Kreisberg, J. I.; Brattain, M. G. Differences in sensitivity of biological functions mediated by epidermal growth factor receptor activation with respect to endogenous and exogenous ligands. J. Biol. Chem. 2002, 277(1), 75-86. Schleh, C.; Semmler-Behnke, M.; Lipka, J.; Wenk, A.; Hirn, S.; Schäffler, M.; Schmid, G.; Simon, U.; Kreyling, W. G. Size and surface charge of gold nanoparticles determine absorption across intestinal barriers and accumulation in secondary target organs after oral administration. Nanotoxicology 2012, 6(1), 36-46. Schwartz, G. K.; Shah, M. A. Targeting the cell cycle: a new approach to cancer therapy. J. Clin. Oncol. 2005, 23(36), 9408-9421. Seo, J. A.; Kim, B.; Dhanasekaran, D. N.; Tsang, B. K.; Song, Y. S. Curcumin induces apoptosis by inhibiting sarco/endoplasmic reticulum Ca2+ ATPase activity in ovarian cancer cells. Cancer Lett. 2016, 371(1), 30-37. Serajuddin, A.; Sheen, P. C.; Mufson, D.; Bernstein, D. F.; Augustine, M. A. Effect of vehicle amphiphilicity on the dissolution and bioavailability of a poorly water‐soluble drug from solid dispersions. J. Pharm. Sci. 1988, 77(5), 414-417. Shah, N.; Carvajal, M.; Patel, C.; Infeld, M.; Malick, A. Self-emulsifying drug delivery systems (SEDDS) with polyglycolyzed glycerides for improving in vitro dissolution and oral absorption of lipophilic drugs. Int. J. Pharm. 1994, 106(1), 15-23. Shen, H.; Zhong, M. Preparation and evaluation of self‐microemulsifying drug delivery systems (SMEDDS) containing atorvastatin. J. Pharm. Pharmacol. 2006, 58(9), 1183-1191. Sherr, C. J. Gl phase progression: cycling on cue. Cell 1994, 79(4), 551-555. Sherr, C. J.; Roberts, J. M. CDK inhibitors: positive and negative regulators of G1-phase progression. Genes Dev. 1999, 13(12), 1501-1512. Slattery, M. (2000). Diet, lifestyle, and colon cancer. Paper presented at the Seminars in gastrointestinal disease. Slattery, M. L. Physical activity and colorectal cancer. Sports Med. 2004, 34(4), 239-252. Slattery, M. L.; Edwards, S. L.; Boucher, K. M.; Anderson, K.; Caan, B. J. Lifestyle and colon cancer: an assessment of factors associated with risk. Am. J. Epidemiol. 1999, 150(8), 869-877. Slomkowski, S.; Alemán, J. V.; Gilbert, R. G.; Hess, M.; Horie, K.; Jones, R. G.; Kubisa, P.; Meisel, I.; Mormann, W.; Penczek, S.; Stepto, R. F. T. Terminology of polymers and polymerization processes in dispersed systems (IUPAC Recommendations 2011). Pure Appl. Chem. 2011, 83(12), 2229-2259. Smith, J.; Mun Tho, L.; Xu, N.; Gillespie, D. A. The ATM-Chk2 and ATR-Chk1 pathways in DNA damage signaling and cancer. Adv. Cancer Res. 2010, 108(C), 73-112. Smyth, H. F.; Carpenter, C. P.; Shaffer, C. B. The subacute toxicity and irritation of polyethylene glycols of approximate molecular weights of 200, 300, and 400. J. Am. Pharm. Assoc. (Scientific ed.) 1945, 34(6), 172-174. Spernath, A.; Aserin, A. Microemulsions as carriers for drugs and nutraceuticals. Adv. Colloid Interface Sci. 2006, 128–130, 47-64. Subramaniam, R.; Mizoguchi, A.; Mizoguchi, E. Mechanistic roles of epithelial and immune cell signaling during the development of colitis-associated cancer. Cancer Res. Frontiers 2016, 2(1), 1. Sun, L.; Wu, S.; Coleman, K.; Fields, K. C.; Humphrey, L. E.; Brattain, M. G. Autocrine transforming growth factor-β1 and β2 expression is increased by cell crowding and quiescence in colon carcinoma cells. Exp. Cell Res. 1994, 214(1), 215-224. Teicher, B. A. (2010). Tumor models in cancer research: Springer Science & Business Media. Thomasset, S. C.; Berry, D. P.; Garcea, G.; Marczylo, T.; Steward, W. P.; Gescher, A. J. Dietary polyphenolic phytochemicals—promising cancer chemopreventive agents in humans? A review of their clinical properties. Int. J. Cancer 2007, 120(3), 451-458. Tiwari, A. K.; Rao, J. M. Diabetes mellitus and multiple therapeutic approaches of phytochemicals: Present status and future prospects. Curr. Sci. 2002, 83(1), 30-38. Tu, Y. S.; Kang, X. L.; Zhou, J. G.; Lv, X. F.; Tang, Y. B.; Guan, Y. Y. Involvement of Chk1–Cdc25A-cyclin A/CDk2 pathway in simvastatin induced S-phase cell cycle arrest and apoptosis in multiple myeloma cells. Eur. J. Pharmacol. 2011, 670(2), 356-364. Visioli, F.; Borsani, L.; Galli, C. Diet and prevention of coronary heart disease: the potential role of phytochemicals. Cardiovasc. Res. 2000, 47(3), 419-425. Walker, D. H.; Maller, J. L. Role for cyclin A in the dependence of mitosis on completion of DNA replication. Nature 1991, 354(6351), 314-317. Wang, J.; Sun, L.; Myeroff, L.; Wang, X.; Gentry, L. E.; Yang, J.; Liang, J.; Zborowska, E.; Markowitz, S.; Willson, J. K.; Brattain, M. G. Demonstration that mutation of the type II transforming growth factor β receptor inactivates its tumor suppressor activity in replication error-positive colon carcinoma cells. J. Biol. Chem. 1995, 270(37), 22044-22049. Wang, Y.; Ji, P.; Liu, J.; Broaddus, R. R.; Xue, F.; Zhang, W. Centrosome-associated regulators of the G 2/M checkpoint as targets for cancer therapy. Mol. Cancer 2009, 8(1), 1. Wei, L.; Sun, P.; Nie, S.; Pan, W. Preparation and evaluation of SEDDS and SMEDDS containing carvedilol. Drug Dev. Ind. Pharm. 2005, 31(8), 785-794. Wu, W.; Wang, Y.; Que, L. Enhanced bioavailability of silymarin by self-microemulsifying drug delivery system. Eur. J. Pharm. Biopharm. 2006, 63(3), 288-294. Xiao, J.; Li, C.; Huang, Q. Kafirin nanoparticle-stabilized pickering emulsions as oral delivery vehicles: physicochemical stability and in vitro digestion profile. J. Agric. Food Chem. 2015, 63(47), 10263-10270. Xiong, Y.; Liu, Q.; Lai, L.; Chen, J. Preparation of the oral self-microemulsifying drug delivery system of GBE50. Acta Pharm. Sinica 2009, 44(7), 803-808. Yu, H.; Shi, K.; Liu, D.; Huang, Q. Development of a food-grade organogel with high bioaccessibility and loading of curcuminoids. Food Chem. 2012, 131(1), 48-54. Zhang, Y.; Wang, R.; Wu, J.; Shen, Q. Characterization and evaluation of self-microemulsifying sustained-release pellet formulation of puerarin for oral delivery. Int. J. Pharm. 2012, 427(2), 337-344.
|