臺灣博碩士論文加值系統

第一部分:
CB / WO3 / SPCE感測器來偵測盧丁，並利用FESEM、XPS、Raman、EIS、CV來觀察感測器對於待測物的靈敏度及各種性質分析，發現所合成的材料擁有很低的LOD 2 nM，並具有0.01至75.46 μM的濃度線性、良好的選擇性、穩定性、重複性。
第二部分:
一種簡單和容易的方法來製造PLL修飾電極，PLL修飾電極具有製備簡單、低成本、電活性的應用種類多、電催化活性高的優點。PLL修飾電極表現出優異的偵測反應和良好的電極穩定性；LSV圖譜更顯示了較寬廣的線性範圍，更低的LOD和優異檢測靈敏度，了解到PLL修飾電極可用於實際生活中不同水樣品裡硫化物的偵測
第三部分:
CS / CA / SPCE修飾電極具有良好的電催化活性，低偵測測限（0.008 μM），寬廣的線性範圍（0.01-115 μM），高靈敏度（8.0947 μAμM-1cm-2），而且對於IZ偵測具有良好的穩定性和高選擇性，即使應用在生物樣品中(人的血清和尿液)偵測IZ仍然表現出令人滿意的RSD值和回復率。

First Part:
CB / WO3 / SPCE sensor was used to detect rutin.FESEM, XPS, Raman, EIS, CV were used to observe the sensors sensitivity and various properties of the test object. It was found that the synthesized material has a very low LOD of 2 nM, and has a concentration of 0.01 to 75.46 μM linearity, good selectivity, stability, repeatability.
Second Part:
A simple and easy method to manufacture PLL modified electrode, PLL modified electrode has the advantages of simple preparation, low cost, electroactive application, and high electrocatalytic activity. The PLL modified electrode exhibits excellent detection response and good electrode stability; the LSV spectrum shows a wider linear range, lower LOD and excellent detection sensitivity, and it is understood that the PLL modified electrode can be used for different water samples in real life sulfide detection
Third Part:
The CS / CA / SPCE modified electrode has good electrocatalytic activity, low detection limit (0.008 μM), wide linear range (0.01-115 μM), high sensitivity (8.0947 μAμM-1cm-2), and IZ detection with good stability and high selectivity, even when applied to biological samples (human serum and urine), the detection of IZ still shows satisfactory RSD value and recovery rate.

目錄
摘要 i
Abstract ii
致謝 iv
表目錄 viii
圖目錄 viii
第一章 緒論 - 0 -
1.1電化學分析簡介 - 0 -
1.2電化學感測器簡介 - 1 -
1.2.1生物化學感測器 - 2 -
1.3 電極 - 3 -
1.3.1化學修飾電極 - 4 -
1.3.2 化學修飾電極的應用 - 5 -
1.4 藥品簡介 - 6 -
1.4.1 三氧化鎢(Tungsten trioxide) - 6 -
1.4.2 碳黑(Carbon Black) - 7 -
1.4.3 離胺酸(L-lysine) - 7 -
1.4.4 炭氣凝膠 (Carbon Aerogel) - 9 -
1.4.5 異煙肼 (Isoniazid) - 9 -
1.4.6 殼聚醣 (Chitosan) - 10 -
第二章 實驗藥品、器材與分析方法 - 11 -
2.1 實驗藥品 - 11 -
2.2 實驗器材 - 12 -
2.3 分析方法 - 13 -
2.3.1 循環伏安法(Cyclic Voltammetry, CV) - 13 -
2.3.2 微分脈衝伏安法(Differential Pulse Voltammetry, DPV) - 14 -
2.3.3 電化學阻抗譜(Electrochemical Impedance Spectroscope, EIS) - 15 -
2.3.4掃描式電子顯微鏡(Scanning Electron Microscope, SEM) - 17 -
2.3.5 穿透式電子顯微鏡(Transmission Electron Microscopy) - 19 -
2.3.6紫外/可見光分光光譜儀(Ultraviolet-Visible Spectrophotometer, UV-Vis) - 20 -
2.3.7傅立葉轉換紅外線光譜儀(Fourier Transform Infrared Spectrometer, FT-IR) - 21 -
2.3.8 拉曼光譜儀(Raman Spectroscopy, Raman) - 23 -
2.3.9 熱重分析儀(Thermogravimetric Analyzer,TGA) - 25 -
第三章 創新的三氧化鎢/碳黑奈米複合物，用於偵測多功能型黃酮類盧丁的經濟實惠 且高效的電化學感測器 - 26 -
3.1前言 - 26 -
3.2合成三氧化鎢/碳黑奈米複合物及製備三氧化鎢/碳黑奈米複合物修飾在網版印刷碳電極 - 27 -
3.3結果討論 - 28 -
3.3.1 表面特徵極化學環境分析 - 28 -
3.3.2 拉曼及電化學組抗圖譜 - 31 -
3.3.3 電極的電催化現象 - 32 -
3.3.4 pH值和掃描速率的影響 - 34 -
3.3.5 盧丁的偵測 - 36 -
3.3.6抗干擾、穩定性、重複性(reproducibility)、重現性(repeatability) - 37 -
3.4 結論 - 39 -
第四章 利用聚L-賴氨酸修飾電極測定水中的硫離子 - 40 -
4.1 前言 - 40 -
4.2 制備PLL修飾在玻璃碳電極上 - 41 -
4.3 結果討論 - 42 -
4.3.1 PLL修飾電極特性 - 42 -
4.3.2 硫化物的偵測 - 45 -
4.3.3 線性掃描伏安法測定硫離子 - 50 -
4.3.4 感測器的選擇性、穩定性和重現性 - 53 -
4.3.5 應用於實際樣品分析 - 53 -
4.4 結論 - 54 -
第五章 利用碳氣凝膠奈米複合物及生化聚合物偵測抗結核物藥物 - 55 -
5.1 前言 - 55 -
5.2 製備CS / CA修飾電極 - 57 -
5.3 結果討論 - 59 -
5.3.1 結構分析 - 59 -
5.3.2 FT-IR及拉曼光譜 - 60 -
5.3.3 BET及TGA的分析 - 60 -
5.3.4 修飾電極的電化學表現 - 62 -
5.3.5 CS / CA修飾電極對IZ的電催化氧化行為 - 63 -
5.3.6 電化學反應的動力學 - 66 -
5.3.7 利用安培法來測定IZ - 68 -
5.3.8 抗干擾 、穩定度及重現性 - 70 -
5.3.9人體血清和尿液中IZ含量的測定 - 71 -
5.4 結論 - 71 -
參考文獻 - 72 -

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