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研究生:范純美
研究生(外文):Chun Mei Fan
論文名稱:大麥飲食介入對成人代謝症候群血液生化指標之成效
論文名稱(外文):The effect of barley on Indicators of metabolic syndrome in adults
指導教授:趙銘崇趙銘崇引用關係
指導教授(外文):M. S. Chao
學位類別:碩士
校院名稱:長庚大學
系所名稱:商管專業學院碩士學位學程在職專班醫務管理組
學門:商業及管理學門
學類:醫管學類
論文種類:學術論文
論文出版年:2019
畢業學年度:107
語文別:中文
論文頁數:65
中文關鍵詞:大麥代謝症候群
外文關鍵詞:barleymetabolic syndrome
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代謝症候群(Metabolic syndrome)是指一組代謝異常疾病或症狀容易出現在同一個人身上,此症候群導致罹患心血管疾病的機會增加。研究顯示全穀類中的燕麥及大麥含豐富的水溶性膳食纖維β-聚葡萄醣(β-glucan),具有降低膽固醇與低密度脂蛋白膽固醇之功效,可減少心臟血管疾病發生的風險。因此本研究以探討大麥飲食介入對成人代謝症候群的指標之影響,大麥飲食是否具有改善代謝症候群各項指標達到日常保健效果,可作為民眾日常生活中飲食主食類另一選擇來源。
研究對象分成實驗組(n=40)與對照組(n=35)共75人,實驗組以大麥介入12週,對照組無任何介入措施,包括參與者的基本屬性及代謝症候群危險因子(包括血壓、腰圍、臀圍、身體質量指數、空腹血糖、膽固醇、三酸甘油脂)。經過12週的大麥飲食介入後,進行後測資料收集,本研究結果發現,實驗組在12週的研究介入後比本研究介入前的體重、身體質量指數(BMI)、腰圍、低密度脂蛋白膽固醇、空腹血糖與舒張壓都有顯著減少(p<0.05),高密度脂蛋白膽固醇有顯著增加(p<0.05),總膽固醇、三酸甘油酯、糖化血色素與收縮壓則無顯著變化(p>0.05)。因此本研究建議具有代謝症候群危險因子者,可將含β-聚葡萄醣的食品列入平日飲食攝取之參考。
Metabolic syndrome refers to a group of metabolically abnormal diseases or symptoms that are prone to occur in the same person, and increases risk of cardiovascular disease. Oats and barley in whole grains are rich in water-soluble dietary fiber β-glucan, which has the effect of lowering cholesterol and low-density lipoprotein cholesterol, and reducing the risk of cardiovascular disease. Therefore, this study explores the impact of barley diet intervention on adult metabolic syndrome. Whether barley diet can be used as another source of choice for dietary staple foods in people's daily lives.
The study patients are divided into experimental group (n=40) and control group (n=35), total of 75 people. The experimental group are with barley intervention for 12 weeks, while the control group are without any intervention. We measure the basic and post intervention attributes and metabolic syndrome risk factors (including blood pressure, waist circumference, hip circumference, body mass index, fasting blood glucose, Cholesterol, triglyceride). After 12 weeks of barley diet intervention, the results found that the experimental group after the 12-week study intervention, body weight, body mass index (BMI), waist circumference, low-density lipoprotein Cholesterol, fasting blood glucose and diastolic blood pressure were significantly reduced (p<0.05), high-density lipoprotein cholesterol was significantly increased (p<0.05), total cholesterol, triglyceride, glycated hemoglobin and systolic blood pressure were not significantly changed (p >0.05). Therefore, this study suggests that people with metabolic syndrome risk factors can include β-glucan-containing foods as a reference for dietary intake.
指導教授推薦書…………………………………………………….
口試委員審定書……………………………………………………..
中文摘要 .........................iii
英文摘要…………………………………………………………....iv
目錄 .........................v
圖目錄 ........................vii
表目錄 ........................viii
第一章 緒論 - 1 -
第一節 研究背景與動機 - 1 -
第二節 研究問題與目的 - 4 -
第二章 文獻探討 - 5 -
第一節 代謝症候群概論 - 5 -
第二節 大麥簡介 - 11 -
第三節 心血管疾病之危險因子探討 - 13 -
第四節 膳食纖維與代謝症候群 - 17 -
第三章 研究方法 - 19 -
第一節 研究設計 - 19 -
第二節 研究流程與研究對象 - 21 -
第三節 研究實驗材料與工具 - 24 -
第四節 統計方法 - 28 -
第四章 研究結果 - 29 -
第一節 研究對象個人基本資料之描述性統計 - 29 -
第二節 實驗組及對照組實驗前後檢驗數據之分佈 - 33 -
第三節 實驗組及對照組試驗前後代謝症候群差異分析 - 36 -
第四節 實驗組實驗前後檢驗數據之差異 - 37 -
第五節 對照組實驗前後檢驗數據之差異 - 39 -
第六節 實驗組與對照組實驗前後檢驗數據之差異 - 41 -
第五章 結論與建議 - 43 -
第一節 結論 - 43 -
第二節 研究建議 - 45 -
第三節 研究限制 - 47 -
參考文獻 - 48 -
一、中文部分 - 48 -
二、英文部份 - 50 -


圖目錄
圖3- 1 每日40公克含3公克β-葡聚醣大麥脆片 - 20 -
圖3- 2 七天份量大麥脆片 - 20 -
圖3- 3 研究實驗流程圖 - 22 -
圖3- 4 測量腰圍方式 - 27 -


表目錄
表2- 1 比較各種代謝症候群的定義 - 7 -
表2- 2 我國代謝症候群的判定標準 - 8 -
表3- 1 代謝症候群相關指標正常值 - 24 -
表3- 2 100公克大麥脆片成分及熱量如下 - 25 -
表4- 1 研究對象個人基本資料變項分佈情形 - 32 -
表4- 2 試驗前後代謝症候群之差異分析 - 35 -
表4- 3 試驗前後代謝症候群之差異分析 - 36 -
表4- 4 實驗組實驗前後檢驗數據之差異分析 - 38 -
表4- 5 對照組實驗前後檢驗數據之差異分析 - 40 -
表4- 6 實驗組與對照組實驗前後檢驗數據之差異分析 - 42 -
一、中文部分
衛生福利部 (2007) 代謝症候群診斷標準。2018年11月23日取自http://www.hpa.gov.tw/BHPNet/Web/HealthTopic/TopicArticle.aspx? No=200712250123&parentid=200712250023

衛生福利部國民健康署102至105年國民營養健康狀況變遷調查報告。2019年3月23日取自
https://www.hpa.gov.tw/Pages/ashx/File.ashx?FilePath=~/File/Attach/10443/File.

許惠恒、蔡敬民、蘇秀悅、劉燦宏、林時逸、李奕德、王俊興、王雅瑜 (2010) 減腰圍、降3高,代謝力健康全書。台北:原水文化。

黃麗卿、黃國晉(2007)。代謝症候群的定義與流行病學。台灣醫學,11(4),363-369。

周慧美(2012)。台北市某國中學生代謝症候群知識、態度及健康行為之研究。(未發表之碩士論文)。國立台灣師範大學健康促進與衛生教育學系,台北市。

黃麟智(2012)。減少台灣代謝症候群發生率與醫療費用之研究。(未發表之碩士論文) 。國立台灣大學管理學院,台北市。

許妙如、廖麗君、張雅如(2012): 代謝症候群與中風.物理治療,37(2), 136-145.

李彩菊(2009)。探討燕麥飲食介入對改善青少年心血管疾病危險因子之影響。(未發表之碩士論文)。台北醫學大學保健營養學研究所,台北市。

美國食品藥物管理局U S Food and Drug Administration(FDA),2019年3月26日取自http://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=101.81

社團法人中華民國糖尿病學會(2018)。書名: 2018 糖尿病臨床照護指 引。出版地:台北市。出版者: 社團法人中華民國糖尿病學會(2018)。

鄭金寶(2007),代謝症候群之臨床營養處置。台灣醫學,11(4),410-416。

二、英文部份
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Aoe, S., Ichinose, Y., Kohyama, N., Komae, K., Takahashi, A., Abe, D., Yanagisawa, T. (2017). Effects of high beta-glucan barley on visceral fat obesity in Japanese individuals: A randomized, double-blind study. Nutrition, 42, 1-6.

Barter, P., Gotto, A. M., LaRosa, J. C., Maroni, J., Szarek, M., Grundy, S. M., Fruchart, J. C. (2007). HDL cholesterol, very low levels of LDL cholesterol, and cardiovascular events. N Engl J Med, 357(13), 1301-1310.

Bi, M., Niu, Y., Li, X., Li, Y., & Sun, C. (2013). [Effects of barley flake on metabolism of glucose and lipids in the patients with impaired fasting glucose]. Wei Sheng Yan Jiu, 42(5), 719-723, 782.

.Booth, A., Worsley, A., Margerison, C., Jorna, M. K., Godfrey, S. J., & Nowson, C. A. (2005). Blood pressure change with weight loss is affected by diet type in men. The American Journal of Clinical Nutrition, 81(5), 983-989.

Brantsæter, A. L., Haugen, M., Samuelsen, S. O., Torjusen, H., Trogstad, L., Alexander, J., Meltzer, H. M. (2009). A Dietary Pattern Characterized by High Intake of Vegetables, Fruits, and Vegetable Oils Is Associated with Reduced Risk of Preeclampsia in Nulliparous Pregnant Norwegian Women. The Journal of Nutrition, 139(6), 1162-1168.
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Carr, D. B., Utzschneider, K. M., Hull, R. L., Kodama, K., Retzlaff, B. M., Brunzell, J. D., Kahn, S. E. (2004). Intra-abdominal fat is a major determinant of the National Cholesterol Education Program Adult Treatment Panel III criteria for the metabolic syndrome. Diabetes, 53(8), 2087-2094.

Cui, W., & Wood, P. J. (2000). - Relationships between structural features, molecular weight and rheological properties of cereal β-D-glucans. In K. Nishinari (Ed.), Hydrocolloids (pp. 159-168).

Franz, M. J., Boucher, J. L., Rutten-Ramos, S., & VanWormer, J. J. (2015). Lifestyle weight-loss intervention outcomes in overweight and obese adults with type 2 diabetes: a systematic review and meta-analysis of randomized clinical trials. J Acad Nutr Diet, 115(9), 1447-1463.

Grundy, S. M., Hansen, B., Smith, S. C., Jr., Cleeman, J. I., Kahn, R. A., American Heart, A., American Diabetes, A. (2004). Clinical management of metabolic syndrome: report of the American Heart Association/National Heart, Lung, and Blood Institute/American Diabetes Association conference on scientific issues related to management. Circulation, 109(4), 551-556.

Gunness, P., Michiels, J., Vanhaecke, L., De Smet, S., Kravchuk, O., Van de Meene, A., & Gidley, M. J. (2016). Reduction in circulating bile acid and restricted diffusion across the intestinal epithelium are associated with a decrease in blood cholesterol in the presence of oat beta-glucan. Faseb j, 30(12), 4227-4238.

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