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研究生:王馨云
研究生(外文):Hsin-Yun WANG
論文名稱:營養對於肌少症老人之影響
論文名稱(外文):Influence of nutrition among elderly people with sarcopenia
指導教授:陳為堅陳為堅引用關係
口試委員:李財坤林先和
口試日期:2019-06-20
學位類別:碩士
校院名稱:國立臺灣大學
系所名稱:國際三校農業生技與健康醫療碩士學位學程
學門:醫藥衛生學門
學類:其他醫藥衛生學類
論文種類:學術論文
論文出版年:2019
畢業學年度:107
語文別:英文
論文頁數:46
中文關鍵詞:肌少症營養補充品蛋白質肌肉人口老化
DOI:10.6342/NTU201900974
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全球的平均餘命持續增長,世界各國都面臨人口老化的挑戰,其中肌少症是高齡社會需面臨的挑戰之一。肌少症定義為隨著年齡增長,肌肉量及身體功能大幅低下的症候群,亦是提高老年人失能、跌倒及死亡率的危險因子。本主題性統整報告目的在找出對於肌少症老人最適合的解決方法,提高老年人肌肉量及肌肉功能藉以降低肌少症所導致的影響。近期研究顯示高品質蛋白質補充加上適當運動訓練計畫可以增加肌少症老人的肌肉量及肌力。本主題性統整報告實行方式為設計並提出一個臨床試驗計畫,對於肌少症老人族群檢測蛋白質補充配合運動訓練在肌肉量及肌肉功能的改變。預期之試驗結果為配合蛋白質補充使用之老人比單純的運動訓練組有更多的肌肉量及肌肉增加。透過進一步研究清楚關於營養對肌少症老人的影響後,未來可以提出一個更容易可行的方式預防或延緩肌少症的發生及進程,並降低肌少症所帶來的個人、社會、經濟層面之負擔。
People worldwide are living longer. All countries face major challenges leading by aging and one of these challenges is sarcopenia. Sarcopenia, defined as the loss of skeletal muscle mass and physical function that occurs with aging, increased the risk of physical disabilities, falls and mortality in the elderly. The aim of this report is to figure out an ideal solution to improve body performance among elderly people with sarcopenia to decrease the impact of sarcopenia. Recent studies showed high-quality protein with exercise training may increase muscle mass and muscle strength in elderly people. The implementation was the proposal of a clinical trial to examine the effect of exercise and protein supplement on muscle mass and physical functions in elderly people with sarcopenia. The anticipated results were participants who will receive protein supplement will have extra muscle mass gain or further improvement on muscle strength compared with exercise alone group. By further researches about the influence of nutrition among elderly people with sarcopenia, people may conclude a readily available means to prevent the occurrence of sarcopenia, which is an increasing morbidity burden for a rapidly aging society and to decrease the personal, social and economic burdens due to sarcopenia.
誌謝 1
摘要 2
Abstract 3
1. General Background and Aims 4
2. Details of Implementation 8
2.1. Learning achievements 8
2.2. The proposal of the effect of exercise and protein supplement on muscle mass, muscle strength, and physical functions in elderly people with sarcopenia: a randomized, double-blind, placebo-controlled trial 9
2.2.1. Introduction 9
2.2.2. Methods 11
2.2.3. Anticipated results 15
3. General Consideration and Outlook 22
References 23
APPENDIX 1: 3-Day Food Intake Record 26
APPENDIX 2: Short Physical Performance Battery Protocol and Score Sheet 34
APPENDIX 3: SF-36 Questionnaire 42
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