臺灣博碩士論文加值系統

背景：運動常作為血壓調控的非侵入式治療之一，相較於有氧運動長期被證實能夠改善心血管系統，過去研究指出阻力運動卻可能會對心血管系統帶來負面效應。運動前血壓值是運動後低血壓反應 (post-exercise hypotension, PEH) 中重要的調節因子 (moderator)，顯示規律運動習慣造成的心血管安靜值差異，可能使運動後心血管反應有所差異。目的：探討不同規律運動習慣的族群進行最大腳踏車運動後，血壓及血流動力學各項指標的變化；並分析運動習慣的不同，是否造成最大運動引起之運動後低血壓反應會有所差異。方法：以橫斷式研究設計，共招募71位年齡介於20至40歲之健康成年人，依運動習慣分為無規律運動組 (N=33)、有氧訓練組 (N=17)、阻力訓練組 (N=21)，進行腳踏車最大運動測試，並於運動前、運動後5分鐘、運動後15分鐘及30分鐘，進行血壓及橈、頸動脈波形測量。結果：阻力訓練組之安靜bSBP、cZc、cPf及rXSPI顯著高於其他兩組 (p< .05)。運動後任一時間點之bSBP與baPWV、cPf、rPeak_Pr、rRPI及rXSPI都呈中度相關 (r皆大於.3)。結論：長期規律阻力訓練確實可能使動脈硬度上升，且使部分血流動力學指標於最大運動後之反應有顯著差異。另外，動脈波形分析之水庫理論，與運動後血壓變化之相關性較高，顯示以水庫理論較能解釋運動後心血管變化情形。

Background: Exercise has been one of the non-invasive treatments for blood pressure regulation. Compared with aerobic exercise which has been proven to improve the cardiovascular function, resistance training may have an adverse impact on cardiovascular system. Pre-exercise blood pressure is an important moderator of post-exercise hypotension. It shows that different BP status, caused by different exercise habits, may bring differences in arterial responses after exercise. Purpose: To evaluate blood pressure, arterial stiffness, and hemodynamics following a maximal aerobic exercise test between groups having different exercise habits. Also, to investigate whether the difference of exercise habits would cause post-exercise hypotension variation after maximal aerobic exercise. Methods: We did a cross-sectional study in 71 healthy adults (aged 20-40 years) with different exercise habits, including the non-exercisers (NE, N = 33), regular aerobic trainers (RAT, N = 17) and regular resistance trainers (RRT, N = 21). Participants underwent an acute bout of graded maximal aerobic exercise. Blood pressure (BP), arterial stiffness, and arterial hemodynamics were measured at baseline, 5-, 15- and 30-min after exercise. Results: RRT group had significantly higher resting bSBP, cZc, cPf and rXSPI than the other groups (p < .05). baPWV, cPf, rPeak_Pr, rRPI and rXSPI showed a moderate correlation with bSBP any time after exercise (r > .3). Conclusion: Regularly engaging in RRT exercise has positive association with higher arterial stiffness. And it does show some differences in arterial hemodynamics responses after exercise between NE, RAT and RRT groups. Overall indices derived from arterial reservoir hemodynamics correlated better with the PEH compared to traditional wave reflection theory. Our research provides evidences supporting that arterial reservoir hemodynamics has proposed a more reasonable explanation for the observed BP changes after exercise.

口試委員會審定書 i
中文摘要 ii
Abstract iii
目錄 v
圖目錄 vii
表目錄 viii
第一章　緒論 1
第一節　問題背景 1
第二節　研究目的 6
第三節　研究假設 6
第二章　研究方法 7
第一節　實驗對象 7
第二節　實驗流程 9
第三節　實驗測量方法 10
第四節　統計方法 13
第三章　研究結果 14
第一節　受試者生理基本特徵 14
第二節　血壓及脈波傳導速率相關變化 14
第三節　動脈波形分析相關變化 17
第四節　皮爾森積差相關分析及多元羅吉斯迴歸分析 20
第四章　討論 22
第一節　最大運動後的生理變化 22
第二節　運動後血壓變化在各組間的差異 23
第三節　動脈硬度指標於運動後的變化 24
第四節　有無運動後低血壓者之運動後變化 30
第五節　相關性及迴歸分析 31
第五章　結論 32
第一節　結論 32
第二節　研究限制 32
第三節　未來研究建議 33
參考文獻 34
附錄一 IPAQ台灣活動量調查短版問卷 41
附錄二 45
附錄三 46
附錄四 47

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