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研究生:曹博凱
研究生(外文):Po-Kai Tsao
論文名稱:開發鎳金屬層狀雙氫氧化物實現非酵素電化學乳酸感測器及應用於非侵入式人體汗液檢測之研究
論文名稱(外文):Developing Ni-based layered double hydroxide for nonenzymatic electrochemical lactate sensor and its application to noninvasive human sweat monitoring
指導教授:陳秀美陳秀美引用關係葉旻鑫
指導教授(外文):Hsiu-Mei ChenMin-Hsin Yeh
口試委員:何國川王孟菊陳冠榮
口試委員(外文):Kuo-Chuan HoMeng-Jiy WangKuan-Jung Chen
口試日期:2020-07-28
學位類別:碩士
校院名稱:國立臺灣科技大學
系所名稱:化學工程系
學門:工程學門
學類:化學工程學類
論文種類:學術論文
論文出版年:2020
畢業學年度:108
語文別:中文
論文頁數:131
中文關鍵詞:乳酸電化學感測器穿戴式非侵入式汗液非酵素層狀雙氫氧化物有機金屬框架
外文關鍵詞:LactateElectrochemical sensorWearableNon-invasiveSweatNon-emzymaticLayered double hydroxideMental organic framework
相關次數:
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致謝 i
摘要 ii
ABSTRACT iv
目錄 v
表目錄 viii
圖目錄 viii
符號說明 xiii
第 1 章 序論 1
1.1 前言 1
1.2 感測器簡介 2
1.2.1 生物感測器簡介 3
1.2.2 電化學感測器簡介 6
1.3 穿戴式感測器簡介 9
1.4 侵入式與非侵入式電化學感測器簡介 11
1.5 乳酸簡介 13
1.6 酵素型乳酸感測與非酵素型乳酸感測器之差異 15
1.7 層狀雙氫氧化物簡介 17
1.8 金屬有機框架簡介 17
第 2 章 文獻回顧與研究目的 22
2.1 不同電催化材料應用於非酵素型電化學乳酸感測器 22
2.1.1金屬氫氧化物應用於非酵素型電化學乳酸感測器 22
2.1.2金屬有機框架應用於非酵素型電化學乳酸感測器 25
2.2 使用金屬氫氧化物應用於電催化領域 28
2.3 使用MOF為前驅物衍生LDH應用於電催化領域 32
2.4 研究動機與架構 35
第 3 章 實驗藥品儀器設備與材料合成方法 39
3.1 實驗藥品 39
3.2 儀器設備 40
3.2.1 電化學恆電位分析儀 41
3.2.2 掃描式電子顯微鏡 46
3.2.3 X-射線繞射分析儀 47
3.2.4 X射線光電子光譜 48
3.2.5 紫外光-可見光光譜儀 49
3.3 材料合成方法 51
3.3.1 使用水熱法合成LDH 51
3.3.2 反應前驅物ZIF-67之合成 51
3.3.3 使用ZIF-67為前驅物轉換成NiCo LDH 51
3.3.4 LDH修飾於網印碳電極 51
第 4 章 探討不同金屬層狀雙氫氧化物對乳酸電催化能力之比較 53
4.1 研究動機 53
4.2 結果與討論 54
4.2.1 探討LDH晶體結構與表面結構之物性分析 54
4.2.2 探討不同金屬LDH對於乳酸之電催化活性 57
4.2.3分析不同金屬LDH修飾之電極對於乳酸之氧化電位 62
4.2.4 分析不同金屬LDH修飾之電極乳酸濃度與電流密度變化 63
4.2.5 探討電化學乳酸感測器之偵測極限與長期穩定測試 68
4.2.6 於模擬汗液成份的電解液探討感測器對乳酸之專一性 71
4.2.7 NiCo LDH修飾之電極與乳酸脫氫酶修飾之電極進行長期穩定測試 74
4.3 結論 75
第 5 章 ZIF-67衍生NiCo LDH作為電催化觸媒應用於非酵素型電化學乳酸感測器 77
5.1 研究動機 77
5.2 結果與討論 78
5.2.1探討ZIF-67晶體結構與表面結構之物性分析 78
5.2.2 探討ZIF-67衍生NiCo LDH晶體結構與表面結構之物性分析 81
5.2.3 使用EDX分析ZIF-67衍生NiCo LDH之金屬成份 84
5.2.4 使用紫外光-可見光光譜儀分析ZIF-67轉換為NiCo LDH所需時間 85
5.2.5 分析ZIF-67衍生NiCo LDH修飾之電極對於乳酸之氧化電位 86
5.2.6 分析ZIF-67衍生NiCo LDH修飾之電極乳酸濃度與電流密度變化 88
5.2.7 探討不同尺度ZIF-67衍生NiCo LDH之電化學表面積 91
5.2.8 探討不同轉換時間ZIF-67衍生NiCo LDH之材料分析以及對於乳酸感測之影響 93
5.2.9 探討電化學乳酸感測器之偵測極限與長期穩定測試以及選擇性測試 95
5.2.10 使用ZIF-67衍生NiCo LDH修飾之電極分析有氧運動與無氧運動的汗液乳酸濃度變化 97
5.3結論 101
第 6 章 結論與建議 102
6.1 結論 102
6.2 建議 106
第 7 章 參考文獻 107
第 8 章 附錄 112
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