臺灣博碩士論文加值系統

隨著科技的發展，腦磁圖(MEG)已成為神經疾病診斷的重要方法。人類活著離不開呼吸這件事，以往的研究揭示呼吸可以影響大腦的活動。本論文探討MEG在不同頻率的呼吸下是否有差異。藉由實驗數據的檢視，結果發現，長呼吸刪除的錯誤標記比短呼吸多，而其他刪除的錯誤標記兩者差異不大。本研究期待能在神經疾病領域上貢獻一份心力，能在未來有更廣泛的應用。

With the development of science and technology, MEG is being an important method for the diagnosis of neurological diseases. Human beings cannot live without breathing. Previous studies have revealed that breathing can affect brain activity. This paper explores whether MEG is different under different frequencies of breathing. Through the inspection of experimental data, it was found that there are more erroneous marks deleted by long breaths than short breaths, and there is not much difference between the other deleted erroneous marks. This research also hopes to contribute to the field of neurological and disease, and have more extensive applications in the future.

目錄
中文摘要…………………………………………….................................i
Abstract………………………………...………………………….……..ii
目錄…………………………………………………………………...…iii
第一章 研究動機與背景………………………………………………..1
1.1呼吸對大腦的影響……………………………………………...1
1.2 α波與呼吸的關聯………………………………………………1
1.3 SQUID…………………………………………………………...2
1.4 MEG介紹……………………………………………………….5
研究目的………………………….…………………………………9
第二章 研究方法……………………………………………………....10
2.1受測者………………………………………………..………...10
2.2儀器設備………………………………………………..……...10
2.3儀器地點……………………………………………………….13
2.4軟體工具……………………………………………………….14
2.5實驗流程………………………………..…….….…………….14
2.6資料紀錄……………………………………………………….15
2.7前處理流程…………………………………………………….16
第三章 實驗分析………………………………………………………22
3.1呼吸分段錯誤標記…………………………………………….22
3.2跳動訊號移除………………………………………………….23
3.3肌肉訊號移除………………………………………………….24
3.4眼動訊號移除………………………………………………….25
3.5心律訊號移除………………………………………………….26
第四章 討論與結論……………………………………………………28
參考文獻………………………………………………………………..29
誌謝……………………………………………………………………..32

 
圖目錄
圖1-1 約瑟夫森接面示意圖…………………………...………..……...3
圖1-2 兩個約瑟夫森節並聯組成SQUID……………………..……….4
圖2-1 MEG主機及周邊配備……………………………….....………12
圖2-2 生理監控儀器 綁帶及主機……………………...……….……13
圖2-3 儀器地點………………………………………………….…….14
圖2-4 屏幕顯示作為受測者呼吸轉換的提示……………….……….15
圖2-5 受測者的實驗流程…………………………………….……….15
圖2-6 藍色線為程式碼所標記的波谷………………….…………….16
圖2-7 紅色框出的錯誤標記…………………………….…………….17
圖2-8 找出錯誤標記數…………………………………….………….17
圖2-9 標記已被刪除……………………………………….………….18
圖2-10 紅色框出的錯誤標記…………………………...…………….18
圖2-11 刪除超出標準值的跳動訊號……………………...………….19
圖2-12 眼動訊號及心律訊號……………………………...………….20
圖2-13 紅色框為心律訊號 藍色框為眼動訊號…………...………...21

 
表目錄
表3-1 呼吸分段的錯誤標記數……………………………………..…22
表3-2 跳動訊號移除數………………………………………………..23
表3-3 肌肉訊號移除數………………………………………………..24
表3-4 眼動訊號移除數………………………………………………..25
表3-5 心律訊號移除數……………………………………………......26

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