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研究生:黃湘喩
研究生(外文):HUANG, XIANG-YU
論文名稱:女性生理期的不適及疼痛程度評估與經痛舒緩乳液之開發
論文名稱(外文):Evaluation of women’s menstrual discomfort and pain level and development of menstrual pain relief lotion
指導教授:林清宮林清宮引用關係
指導教授(外文):LIN, CHING-GONG
口試委員:黃昭菱甘其銓
口試委員(外文):HUANG, JAU-LINGKAN,CHI-CHUAN
口試日期:2022-09-15
學位類別:碩士
校院名稱:嘉南藥理大學
系所名稱:藥學系
學門:醫藥衛生學門
學類:藥學學類
論文種類:學術論文
論文出版年:2022
畢業學年度:110
語文別:中文
論文頁數:80
中文關鍵詞:生理不適經痛感覺程度精油當歸芍藥散乳液
外文關鍵詞:physiological discomfortdegree of menstrual painessential oilDanggui Shaoyao Sanlotion
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經痛對於大多數女性在日常生活方面有許多負面影響,本論文透過網路問卷的方式,探討女性在月經來潮時,經痛及生理不適的情形,利用當歸芍藥散及精油,開發經痛舒緩乳液。
網路問卷利用短格式McGill疼痛量表、經期生理不適量表、數字疼痛評估量表,探討女性在月經來潮時生理不適的症狀及疼痛的感覺程度。經期生理不適量表之結果顯示,倦怠、腰痠背痛、下腹部腫脹為生理不適狀況中較常見的現象,經痛平均強度屬於中度疼痛。以平均數及標準差比較基本變項與疼痛感覺、生理不適、經痛強度之間的差異,結果顯示,在疼痛感覺、生理不適、經痛強度方面,經期與經痛時間長者皆比經期與經痛時間短者感受強烈;而月經週期為不規則者比起月經週期為規則者在疼痛感覺、生理不適、經痛強度方面較顯著。
當歸芍藥散利用口服方式,具有改善經痛的效果,本研究探討以外用方式將當歸芍藥散結合馬鬱蘭、冬青、辣椒精油與薄荷腦,製備經痛舒緩乳液,比較使用前後經期長度、經痛持續時間以及經痛強度之感受,結果顯示,經痛舒緩乳液使用前經痛持續時間由平均2.96±1.22天,下降為平均2.15±0.97天;經痛強度由疼痛分數平均5.65±1.70,下降為平均3.81±2.02,改善效果顯著,顯示外用含當歸芍藥散之經痛舒緩乳液,可縮短經痛持續時間及緩解經痛強度,具有商業開發價值。
Menstrual pain has many negative effects on the daily life of most women. This study used an online questionnaire to explore women's menstrual pain and physical discomfort during menstrual cramps, and developed menstrual pain relief lotion by using Danggui Shaoyao San and essential oils.
The online questionnaire used the short form McGill pain questionnaire (SF-MPQ), menstrual distress questionnaire (MDQ), and numerical rating scale (NRS) to explore the symptoms of women's physical discomfort and the degree of pain during menstruation. The results of the menstrual distress questionnaire showed that burnout, low back pain, lower abdominal swelling and the average intensity of menstrual pain was a moderate degree of pain. Differences between basic variables and pain sensation, physical discomfort, and intensity of menstrual pain were compared by means and standard deviations. Those with extended menstrual periods and menstrual pain days had stronger in pain sensation, physiological discomfort, and menstrual pain intensity than those with shorter menstrual periods and menstrual pain days. Compared with those with regular menstrual cycle, those with irregular menstrual cycle have more significant pain sensation, physiological discomfort and menstrual pain intensity.
Danggui Shaoyao San has the effect of improving menstrual pain by taking orally. In this study, Danggui Shaoyao San combined with marjoram, wintergreen, capsicum essential oil, and menthol crystal was used to prepare menstrual pain relief lotion, and the menstrual period length, menstrual pain duration and menstrual pain intensity before and after use were compared. The results showed that the duration of menstrual pain before using the menstrual pain relief lotion decreased from an average of 2.96±1.22 days to an average of 2.15±0.97 days; the intensity of menstrual pain decreased from an average of 5.65±1.70 to an average of 3.81±2.02, and the improvement effects were significant. It showed that the menstrual pain relief lotion containing Danggui Shaoyao San for external use can shorten the duration of menstrual pain and relieve the intensity of menstrual pain, and has commercial development value.
中文摘要 I
Abstract III
致謝 IV
目錄 V
圖目錄 VII
表目錄 VIII
第一章 緒論 1
1-1 研究背景與動機 1
1-2 研究目標 4
第二章 文獻回顧 5
2-1 月經的形成與介紹 5
2-2 月經週期階段 5
2-3 經痛的定義與原因 6
2-4 經痛緩解方式 7
2-5 中醫對經痛的解釋 8
2-6 芳香療法的介紹 10
第三章 研究材料及方法 15
3-1 研究架構 15
3-2 實驗材料 16
3-3 當歸芍藥萃取 18
3-4 當歸芍藥散萃取液對皮膚功效之測試 19
3-5 精油混合物在皮膚的耐受度測試 21
3-6 經痛舒緩乳液調製 21
3-7 經痛舒緩乳液用於皮膚刺激性測試 22
3-8 經痛舒緩乳液試用對象 22
3-9 經痛舒緩乳液試用方式 22
3-10 經痛舒緩乳液劑型之回饋方式 23
3-11 網路問卷研究對象 24
3-12 網路問卷之研究方式 25
3-13 網路問卷之研究工具 25
3-14 網路問卷信度 27
3-15 資料處理與分析 28
3-16 研究倫理 28
第四章 研究結果與討論 29
4-1 網路問卷信度分析結果 29
4-2 問卷基本資料及月經週期相關資料分析 29
4-3 當歸芍藥散萃取液對皮膚功效之測試結果 49
4-4 精油混合物在皮膚的耐受度測試結果 52
4-5 經痛舒緩乳液開發結果 53
4-6 經痛舒緩乳液用於皮膚刺激性測試結果 55
4-7 經痛舒緩乳液試用對象與網路問卷研究對象月經資料比較 56
4-8 使用經痛舒緩乳液前後經期長度變化 60
4-9 使用經痛舒緩乳液前後經痛持續時間變化 62
4-10 使用經痛舒緩乳液後經痛強度變化 64
4-11 經痛舒緩乳液使用感受 67
第五章 結論與未來展望 70
5-1 結論 70
5-2 未來展望 71
參考文獻 72
附錄一 人類研究倫理審查通過證明書............................ 附錄1
附錄二 生理期問卷.............. ............................ 附錄2
附錄三 經痛舒緩乳液使用前問卷............................... 附錄14
附錄四 經痛舒緩乳液使用後問卷............................... 附錄19
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