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研究生:蘇鈺茹
研究生(外文):SU, YU-RU
論文名稱:比較有酒駕的酒精使用症者、無酒駕的酒精使用症與健康成人於虛擬交通情境的腦波表現與決策行為之差異:一初探研究
論文名稱(外文):Differences in Brainwave Patterns and Decision-Making in Virtual Traffic Scenarios among Individuals with Alcohol Use Disorder and a History of Driving Under the Influence, those with AUD without a DUI History, and Healthy Adults: An Exploratory Study
指導教授:葉品陽葉品陽引用關係
指導教授(外文):YEH, PIN-YANG
口試委員:邱献章廖瑞銘葉品陽
口試委員(外文):CHIU, HSIEN-JANELIAO, RUEY-MINGYEH, PIN-YANG
口試日期:2024-04-18
學位類別:碩士
校院名稱:亞洲大學
系所名稱:心理學系
學門:社會及行為科學學門
學類:心理學類
論文種類:學術論文
論文出版年:2024
畢業學年度:112
語文別:中文
論文頁數:128
中文關鍵詞:酒駕酒精使用症反應抑制注意力決策
外文關鍵詞:Drive Under Influence of AlcoholAlcohol Use DisorderInhibitory controlAttentionDecision making
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研究背景:儘管國內對於酒駕(driving under the influence of alcohol, DUI)罰則不斷加重,但該問題依舊嚴重。研究指出,多數被臨檢的酒駕者均非偶爾誤犯,意即酒駕者與酒精使用症(Alcohol Use Disorder, AUD)於神經生理反應(如靜息態腦波快慢波比值異常)與神經心理表現(如抑制困難與衝動決策)有相似之處,但目前尚缺乏本土相關研究資料。此外,為接近真實駕駛環境,瞭解AUD者的實際可能表現(如駕駛專注度),所以運用虛擬實境技術模擬駕駛情境。
研究目的:本研究欲探討有酒駕事實之AUD者、無酒駕事實之AUD者與非AUD者,於反應抑制、決策,以及涉及注意力之特定駕駛情境的腦波變化。
研究方法:參與者來源為衛福部桃園療養院成癮治療科門診之酒精使用症者,須具備駕駛車輛資格與能力。參與者分為有酒駕事實之AUD組(AUDwDUI組)16名、無酒駕事實之AUD組(AUDwoDUI組)11名與非AUD組14名,共41位參與者。須完成飲酒狀況量表(華人酒癮篩檢問卷與酒精使用疾患確認檢測)、情緒相關量表(臺灣人憂鬱量表與情緒調節量表)、神經心理測驗(停止訊號作業-交通號誌版與愛荷華賭博測驗),以及虛擬實境的情境(誘發注意力反應的交通影片)。
研究結果:三組於神經心理測驗表現上均未有顯著差異。腦波部分,三組之絕對功率均有顯著差異,然而AUDwoDUI組的快慢波比率數值更低,另外,兩兩比較的腦波連結性有顯著差異。
結論與建議:無酒駕AUD者的額葉活動相對活躍且不受環境刺激強弱影響,且無酒駕事實AUD者的高額葉活躍應非意識控制注意力資源,而是高監控(或警戒)之表現。有酒駕事實AUD者於缺乏外在刺激的情境時,其全腦的低頻腦波連結性相對較強,推估其全腦可能處於昏沈(drowsiness)狀態。

Background:
Despite the increasing penalties for driving under the influence of alcohol (DUI) in Taiwan, the problem of DUI remains serious. Past literatures indicate that most pulled over DUI are not negligence; furthermore, similarities between DUI offenders and individuals with Alcohol Use Disorder (AUD) in terms of neurophysiological responses (e.g., abnormal theta/beta ratio in resting EEG) and neuropsychological performance (e.g., deficits in inhibition and impulsive decision-making), although local research on this topic is lacking. Additionally, to make experimental stimulus as close to real driving circumstance as possible and better understand the actual performance of individuals with AUD, such as their attentional focus while driving, virtual reality technology is being used to simulate driving scenarios.
Purpose:
This study aims to investigate differences in inhibitory control, decision-making performance, and brainwave changes related to attentional demands in specific driving situations among individuals with AUD with DUI, individuals with AUD without DUI, and non-AUD individuals.
Methods:
The AUD group participants with a valid driver's license and driving ability were recruited from senior psychiatrists at Division of Addiction Treatment of Taoyuan Psychiatric Center in Taiwan. The non-AUD group consisted of data from Prof. Yeh's laboratory database. The participants were divided into three groups: AUD with DUI (n=16), AUD without DUI (n=11), and non-AUD (n=14), with a total of 41 participants. All participants completed alcohol-related questionnaires (C-CAGE Questionnaire and Alcohol Use Disorders Identification Test), emotion-related questionnaires (the Emotion Regulation Questionnaire and the Taiwanese Depression Scale), neuropsychological tests (Stop signal task-traffic light images and Iowa Gambling Task), and a virtual reality scenario (traffic video designed to elicit attentional responses).
Result:
There were no significant differences among the three groups in terms of neuropsychological test performance. As regards brainwave activity, no significant differences exist in absolute power among the three groups. However, the AUD without DUI group showed a lower theta/beta ratio and significant differences in pairwise comparisons of brainwave coherence.
Discussion:
Individuals with AUD without DUI’s frontal lobe activity was more active than other groups and was relatively not affected by the intensity of environmental stimuli. Moreover, the high frontal activity in this group is a manifestation of heightened vigilance rather than conscious control of attentional resources. Individuals with AUD with DUI showed stronger low-frequency brainwave coherence across the whole brain in situations with fewer external stimuli, presuming a state of drowsiness.
摘要 i
Abstract ii
目錄 v
圖目次 viii
表目次 ix
第一章、緒論 1
第一節、酒駕與危險駕駛者 1
第二節、酒駕與酒精使用症相關之神經生理基礎 5
一、 酒精使用症之定義與診斷 5
二、 神經傳導物質 6
三、 靜息態腦波與情境下的腦波變化 7
第三節、酒精使用症易為酒駕之神經心理基礎 11
一、 涉及道路駕駛之神經心理功能 11
二、 酒精使用症與酒駕之反應抑制表現 12
三、 酒精使用症與酒駕之決策表現 14
第四節、酒精使用症之共病 17
第五節、研究目的與問題假設 20
第二章、研究方法 21
第一節、研究對象 21
第二節、研究設備與工具 22
一、 量表工具 22
二、 神經心理測驗 23
三、 腦波 26
四、 頭戴式虛擬實境顯示器與其內容 30
第三節、研究程序 33
第四節、統計分析 35
第三章、研究結果 36
第一節、人口學變項分析 36
第二節、神經心理測驗表現 38
第三節、腦波數據 45
一、 絕對功率 45
二、 快慢波比值 52
三、 不同腦區間的連結性 54
第四章、討論 92
第一節、主要發現 92
第二節、與人口學變項有關之結果 93
第三節、腦波測量用於區辨酒駕之優勢 97
一、 絕對功率 97
二、 快慢波比值 98
三、 連結性 98
第四節、神經心理測驗用於區辨酒駕之潛在問題 100
一、 反應抑制 100
二、 決策 101
第五節、研究限制 103
一、 研究對象之限制 103
二、 研究工具之限制 103
第五章、結論 104
參考文獻 105
一、 中文 105
二、 外文 106

圖目次
圖2-1停止訊號作業-交通號誌版流程圖 25
圖2-2 VR裝置結合腦波儀 28
圖2-3腦波實驗的國際10-20系統(黃底為測量點位) 29
圖2-4穿戴VR示意圖 31
圖2-5誘發注意力反應的交通影片情境 32
圖2-6 AUD組之研究流程圖 34
圖3-1三組各區塊選擇有利牌組傾向之差異 44
圖3-2非AUD組於基準期腦波功率表現 46
圖3-3 AUDwoDUI組於基準期腦波功率表現 47
圖3-4 AUDwDUI組於基準期腦波功率表現 48
圖3-5非AUD組於試驗期腦波功率表現 49
圖3-6 AUDwoDUI組於試驗期腦波功率表現 50
圖3-7 AUDwDUI組於試驗期腦波功率表現 51
圖3-8比較AUDwDUI組與AUDwoDUI組於基準期腦波連結性表現 70
圖3-9比較AUDwDUI組與非AUD組於基準期腦波連結性表現 71
圖3-10比較AUDwoDUI組與非AUD組於基準期腦波連結性表現 72
圖3-11比較AUDwDUI組與AUDwoDUI組於試驗期腦波連結性表現 89
圖3-12比較AUDwDUI組與非AUD組於試驗期腦波連結性表現 90
圖3-13比較AUDwoDUI組與非AUD組於試驗期腦波連結性表現 91

表目次
表1-1各國酒駕之血液酒精濃度標準與酒精相關之死亡事故率(%) 3
表3-1三組之人口學變項的平均值與標準差 37
表3-2三組於停止訊號測驗(紅綠燈版)之表現 39
表3-3三組於停止訊號測驗(黃綠燈版)之表現 41
表3-4三組於愛荷華賭博測驗之表現 42
表3-5愛荷華賭博測驗各區塊之敘述統計 43
表3-6愛荷華賭博測驗(IGT)區塊分析之二因子變異數分析(3x5)摘要表 43
表3-7三組於誘發注意力反應之交通影片之TBR值表現 53
表3-8比較AUDwDUI組與AUDwoDUI組於基準期腦波連結性表現 55
表3-9比較非AUD組與AUDwDUI組於基準期腦波連結性表現 60
表3-10比較非AUD組與AUDwoDUI組於基準期腦波連結性表現 65
表3-11比較AUDwDUI組與AUDwoDUI組於試驗期腦波連結性表現 74
表3-12比較非AUD組與AUDwDUI組於試驗期腦波連結性表現 79
表3-13比較非AUD組與AUDwoDUI組於試驗期腦波連結性表現 84
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