臺灣博碩士論文加值系統

目的：
失眠症在現代社會裡是一個相當普遍病症，隨著年歲的增加而失眠患者比例亦有所增加。中醫針灸其臨床治療功效都已受到醫學界肯定，其優點是患者沒有對藥物依賴性或成癮性的疑慮。本研究將以針灸針刺足太陰脾經之三陰交穴位Sanyiniao (SP6)作用，而針對十二經絡能量數值與腦波各種波型變化等差異性之臨床相關研究，藉以能找出其針灸對有助於失眠患者治療找到新依據。
方法:
收案標準以失眠門診就醫者，凡年滿20歲以上至75歲之男性、女性；匹茲堡睡眠品質量表(PSQI)總分等於或大於5分以上者。收案70人，以單盲試驗隨機分配方式進行分成二組【實驗組：35人；對照組：35人】，於安靜舒適環境下，以針灸針刺三陰交穴Sanyiniao (SP6)，以良導絡偵測儀器與腦波分析儀器，檢測記錄相關數據分別對於針灸之前、後各測量一次。
結果:
將良導絡與腦波所測量的數據進行實驗組與對照組作成前、後測之四組數字資料比對分析，結果顯示針灸作用，在良導絡方面結果顯示，手太陰肺經、手厥陰心包經、手少陰心經、手太陽小腸經、手陽明大腸經、足太陰脾經、足太陽膀胱經，其分析比較其P值＜0.05，顯示出實驗組與對照組確實有其差異性；而在腦波方面，以Delta(δ)波0.5-2.75Hz、High Alpha(α)波10-11.75Hz、Low Beta(β)波13-16.75Hz，其分比較其P值＜0.05，顯示出實驗組與對照組確實有其差異性。
結論：
本研究的結果顯示以針灸對於刺激三陰交的穴位(SP6)作用，在實驗組與對照組二組間之良導絡和腦波變化的研究過程及分析結果也看到有其相關的差異性的改變，也相對說明了針灸對於經絡氣血的運轉與腦波變化有其一定相連性，但如果僅僅依其相關變化即作為針灸與失眠患者相關的依據，確實需要更多的研究的實驗來做為進一步證明。

Acupuncture Effect at Sanyiniao(SP6) on Meridian and Electroencephalography (EEG) Changes in Insomnia.

Background:
Insomnia is a common symptom in the modern era and the prevalence is up to 9-12% in general population. It occurs more in the eldery. The acupuncture has more than 2000 years in Traditional Chinese Medicine (TCM) history, and it was effective and well-accepted by patients. Acupuncture has excellent efficacy in treating insomnia and avoids the risk of sedatives addiction.
Objective:
To estimate the acupuncture effect at Sanyiniao (SP6) on meridian and cortical electric activities changes In Insomnia patients.
Methods:
We collected 70 insomnia objectives from the clinic then divided patients into two equal groups (35 treatment group and 35 placebo group) with randomized, single-blind method. We used the synchronized Meridian Energy Analysis Device (MEAD) and the electroencephalography (EEG) in a quiet and comfortable environment to record the patients’ meridian and cortical electric changes before and after the acupuncture and sham acupuncture at SP6, respectively.
Results:
We analyzed the data between acupuncture and placebo group. From the MEDA data, it showed meridian changes in Lung meridian of Hand-Taiyin, Pericardium meridian of Hand-Jueyin, Heart meridian of Hand-Shaoyin, Small Intestine meridian of Hand-Taiyang, Large Intestine meridian of Hand-Yangming, Spleen meridian of Foot-Taiyin, Bladder meridian of Foot-Taiyang (p <0.05). On the other aspect, the EEG data showed significant difference in Delta (δ) wave (0.5-2.75 Hz), High Alpha (α) wave (10-11.75 Hz), Low Beta (β) wave (13-16.75 Hz) ( P < 0.05).
Conclusion:
Acupuncture at SP6 point for insomnia patient, indeed led to the changes in meridian and EEG. We could not only measure Ying-Yang energy changes in meridians but also caught the synchronized changes in EEG. This highlights the acupuncture hand central nervous system effect. Further study is needed to establish the quantitative changes about meridian network, Ying-Yang balance, and EEG changes.
Keywords
EEG, Meridian Energy Analysis Device(M.E.A.D.), Acupuncture, Meridian, Qi, Insomnia

目錄
圖目錄.................................................vi
表目錄.................................................vii
中文摘要................................................1

第一章 前言............................................3
1.1研究背景....................................... ...3
1.2研究目的...........................................3
第二章 文獻探討.........................................5
2.1針灸醫學理論學說.................................. 5
2.1.1針灸治療的相關理論........................... 5
2.2良導絡.............................................6
2.3腦波(EEG) 定義.....................................8
2.4選擇三陰交腧穴基礎理論.............................8
第三章 材料與方法.......... ...........................10
3.1受試者............................................ 10
3.2納入條件...........................................10
3.3排除條件...........................................10
3.4過程...............................................10
3.4.1各組的檢測過程...............................11
3.5良導絡檢測.........................................12
3.5.1良導絡檢查儀器...............................12
3.5.2受試者以良導絡測量之順序.....................12
3.6腦波檢測...........................................13
3.7實驗流程...........................................15
3.7.1良導絡.......................................15
3.7.2腦波.........................................16
3.8分析...........................................16
第四章 結果.............................................17
4.1受試者基本資料.....................................17
4.2受試者良導絡之針灸前、後結果......................17
4.3受試者腦波之針灸前、後結果........................22
第五章 討論.............................................27
第六章 結論.............................................28
參考文獻.................................................29
附錄.....................................................31
英文摘要.................................................37
作者簡歷.................................................39
謝辭.....................................................40

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