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Ultrasound is a very good power source for doing the hyperthermia treatment since it owns the properties such as penetration, scan, focus, flexibility, and so on. Several investigators have been studying the ultrasound hyperthermia using the external heating method through one or several ultrasound transducers. Very good treatment results for the superficial tumors have been obtained during the clinical patient trials. In contrast to the superficial heating method, a deep heating method must be employed to obtain good heating patterns when tumors are located in the deep-seated regions. Thus for the first portion of this thesis we study the relationship between the heating depth and the transducer parameters (frequency, diameter and radius of curvature) based on the bioheat transfer equation. Secondly, we have chosen a single , fixed (frequency, diameter and radius of curvature) transducer, scanning a single circle or double circles, around a given tumor with fixed blood perfusion. The following five system parameters can be varied: acoustic output power magnitude, the depth of focus of the ultrasonic beam in the tissue, the size of the scan circle, and the transducer rotation and tilt angles. The steady- state bioheat transfer equation is used to determine that set of these five scan parameters which can result in suitable steady- state tissue temperature distributions under a variety of tumor and normal tissue conditions. These results are then extended to form a stationary multiple-transducer system which can be employed to heat different types of tumors. This simulation study can be used as the guideline for designing a new external heating system and for the further treatment planning.
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