臺灣博碩士論文加值系統

本研究計畫將對照射發光玻璃劑量計系統進行改良，整套系統以同軸方式量測，將提高雷射的聚焦與對焦成像效果，結果均獲得明顯改善，感光耦合元件系統CCD與光電倍增管系統PMT兩者可以進行切換。同時我們也改良樣品座，提高樣品穩定度，使對焦時間與量測時間減少使量測方便性提升及量測時間大幅減少。以兩種方式對小尺寸直徑1.5mm、長度1.8mm，共量測115支1Gy同劑量的照射發光玻璃輻射劑量計（radiophotoluminescent glass dosimeter, RPLGD）做進一步分析及檢測。圓面量測訊號在平均值百分誤差±5%內之樣品數量與舊系統比較，從71%上升到75%。改良後的同軸玻璃輻射測量儀，在線性迴歸分析中套用相同模型都與舊系統的線性趨勢相同。我們改變之前照射發光訊號強度對輻射劑量之關係式，使關係式能更貼近生命週期(Lifetime)，將之累計輻射劑量計讀。

The research intends to improve the system of Radio-Photoluminescence Glass Dosimeter (RPLGD). It has significant progress on elevating the ability of laser focusing and the quality of image-forming with coaxial measurement. The results also show that Charge-coupled Device(CCD) and Photomultiplier(PMT) can be switched. Meanwhile, the research enhanced the stability of RPLGD holder that it was obviously shorten the time of focusing and measurement and more convenience to test. For further analysis and detection, the research measured 115 pieces of 1 Gy samples which are 1.5 mm of diameter and 1.8 mm of length in two kinds of experimental modes. To compare with the previous system, the results of the round face measurement with same amount of samples which are within ±5% error in average value were raised from 71% to 75%. To apply the same formula to linear regression analysis, the developed RPLGD has the same linear trending as the previous system. Thus, the research adjusted the relationship between the intensity of the luminescence signal and the radiation dose to make the model much near to the lifetime then examining the doses of cumulative radiation.

目錄
摘要…………………………………..………………………………..i
Abstract……………………………………………………………….ii
目錄…………………………………………………………………..iii
圖目錄………………………………………………………………...v
表目錄……………………………………………………………….vii
1.緒論…………………………………………………………………1
1.1.前言………………………………………………………….1
1.2.研究動機.……………………………………………………2
1.3.研究目的…………………………………………………….3
2.介紹…………………………………………………………………4
2.1.輻射介紹…………………………………………………….4
2.2.人員輻射劑量計比較……………………………………….7
2.3.膠片佩章…………………………………………………….9
2.4.熱發光劑量計……………………………………………...10
2.5.光刺激發光劑量計………………………………………...12
2.6.照射發光玻璃劑量計……………………………………...13
3.實驗架構…………………………………………………………..16
3.1.雷射光源…………………………………………………...17
3.2.聚焦鏡組…………………………………………………...17
3.3.濾片………………………………………………………...17
3.4.顯微鏡……………………………………………………...18
3.5.感光耦合元件……………………………………………...18
3.6.光電倍增管………………………………………………...19
3.7.照射發光玻璃樣品...………………………………………20
3.8.照射發光螢光訊號分析…………………………………...22
4.實驗結果…………………………………………………………..23
4.1.實驗裝置改良……………………………………………...24
4.2.底座改良…………………………………………………...26
4.3.CCD&PMT置換改良....…………………………………...29
4.4.CCD擷取照射發光訊號影像分析………………………..29
4.5.PMT擷取照射發光訊號生命週期分析…………………..33
4.6.PMT與CCD系統比較……………………………………41
5.總結………………………………………………………………..42
6.參考文獻…………………………………………………………..44

[1] J. H. Schulman, W. Schureliff, R. J. Ginther, F. H. Attix. Radiophotoluminescence Dosimetry System of the US Navy. Nucleonics. 1953; 11(10): 52
[2] Kurobori, Toshio; Yanagida, Yuka; Chen, Yao Qiang，A three-dimensional imaging detector based on nano-scale silver-related defects in X- and gamma-ray-irradiated glasses. 2016; 55 ( 2 ) , p.02
[3] Z. Ruihua, L. Boyang & Z.Jianhuan, A new method for the UV excitation in radiophotoluminescence dosimetry, Radiation Protection Dosimetry, 1986; 17 (1-4): 299-302.
[4] E. Piesch, B. Burgkhardt, M. Vilgis, Photoluminescence dosimetry: progress and present state of art. Radiat. Prot. Dosim. 1990; 33: 215-226
[5] 人員輻射劑量評定機構認可及管理辦法第一條、第三條，行政院原子能委員會，會輻字第0960020119號，2007
[6] 許世明、陳為立、林美秀、葉善宏，照射發光玻璃劑量計之研究現況，輻射防
護簡訊64，財團法人中華民國輻射防護協會，2003，7-11
[7] 許彬杰、翁寶山，實用固體熱發光劑量測定術，合記圖書出版社，2002，33-35
[8] Sun, Li-Min; Huang, Chih-Jen; Chen, Hsiao-Yun, Evaluating the consistency of location of the most severe acute skin reaction and highest skin dose measured by thermoluminescent dosimeter during radiotherapy for breast cancer. 2016;41 (3): 216–220
[9] David Y.C. Huang and Shih-Ming Hsu. Radio-Photoluminescence Glass Dosimeter (RPLGD)，Advances in Cancer Therapy，2011，Prof. Hala Gali-Muhtasib (Ed.)，ISBN: 978-953-307-703-1
[10] 許世明、葉善宏、林美秀、陳為立，照射發光玻璃劑量計與熱發光劑量計量測輻射劑量之特性比較，中華放射醫誌 Chin J Radiol，2004，29
[11] H. E. Johns, J. R. Cunningham， 最新放射物理學The Physics of Radiology，第四版，蔡榮煌譯、翁寶山校正，新竹黎明出版社，1983: 37-70
[12] Hsu S.M., Yeh S.H., Lin M.S. and Chen W.L. ，Comparison on Characteristics of Radiophotoluminescent Glass Dosemeters and Thermoluminescent Dosemeters，Radiat. Prot. Dosim，2006;119(1-4):327-31
[13] 行政院原子能委員會，公開授權網站資料，2010
[14] 游離輻射防護安全標準第一條、第二條、第四條、第六至十五條，行政院原子能委員會，會輻字第0940041080號，2005
[15] United Nations Scientific Committee on the Effects of Atomic Radiation. Sources and effects of ionizing radiation. New York: United Nations. 2008 (published 2010): 4 [9 November 2012]. ISBN:978-92-1-142274-0.
[16] 劉祺章，黃富祈，羅會義，游勝路，小林育夫，岸根孝行，劉衣祺，許芳裕。光激螢光環境劑量計不確定度與最低可測限值評估，臺灣應用輻射與同位素雜誌，Sep 2012，Vol. 8， No. 3，301-310
[17] James H. Schulman, Frank H. Attix, Edward J. West and Robert J. Ginther New Thermoluminescent Dosimeter. 1960;31(12):1263
[18] K. Tabushi, S. Koyama, M. Homma, Y. Aoyama, Y. Namito, S. Ban, H. Hirayama，Evaluation of energy characteristics of glass dosimeter using synchrotron radiation”, Instrumentation and Technique.2003;14C1，331
[19] K. Yamazaki, S. Tonouchi and T. Hashimoto，Cumulative dose measurements using radiophotoluminescence glass dosimeter in cold areas，Journal of Radioanalytical and Nuclear Chemistry.2003;255[3]，565.
[20] 許世明，葉善宏，林美秀，陳為立 照射發光玻璃劑量計與熱發光劑量計偵測輻射特性之比較研究，2003，中華放射線醫學雜誌.2004; 29卷6期，P323 – 330
[21] V. V. Antonov-Romanovskii, I. F. Keirum-Marcus, M. S. Poroshina, Z. A. Trapeznikova, Conference of the academy of sciences of the USSR on the peaceful uses of atomic energy. 1956;USAEC Report AEC-tr-2435 1, 239-250.
[22] E. N. Sanborn, E. L. Beard, Sulfides of strontium, calcium and magnesium in infra-red stimulated luminescence dosimetry. Proceeding of the first international conference on luminescence dosimetry.1967;USAEC, 183-191.
[23] L. B?tter-Jensen, N. Agersnap Larsen, B. G. Markey, S. W. S. McKeever, Al2O3:C as a sensitive OSL dosemeter for rapid assessment of environmental photon dose rates. Radiat. Meas.1997; 27, 295-298.
[24] M. S. Akselrod, L. B?tter-Jensen, S. W. S. McKeever, Optical stimulated luminescence and its use in medical dosimetry. Radiat Prot Dosimetry.2007;41, S78-S99.
[25] Chiyoda Technol Corporation，Personal monitoring system by glass badge，2003.
[26] 株式会社千代田Ъヱвю，蛍光ヮьЗ線量計・小型素子ЁЗЪу説明資料， 2014
[27] Y. Miyamoto, K. Kinoshita, S. Koyama, Y. Takei, H. Nanto, T. Yamamoto, M. Sakakura, Y. Shimotsuma, K. Miura, K. Hirao. Emission and excitation mechanism of radiophotoluminescence in Ag+-activated phosphate glass. Elsevier, Nuclear Instruments and Methods in Physics Research A. 2010; 619: 71-74.
[28] 池上 徹. 窒素ヮЗяみЕメ用ゆギヮьЗ線量計эみФズコゆサ. Japan: 放射線. 1991;17(3): 10-17
[29] Andor Learning center, CCD Sensor Architectures, andor.com
[30] All rights reserved©Shanghai Hapstar M&E Equipment Co. Ltd.
[31] ColinEberhardt, Photomultiplier tube, Wikimedia Commons, 2005