臺灣博碩士論文加值系統

腹膜透析所導致的腹膜炎中包含了許多的因素，其中因素有糖尿病、心血管疾病、插管位置等，而臨床研究者除了關心其因子外還注意到所發生腹膜炎可分為同菌種與不同菌種。醫學上常常只採計”有確實觀察到發生腹膜炎的個案”做為所使用的樣本資料。但此觀察方法容易造成截切資料，使用之樣本數較少。本論文採競爭風險的觀點來分析資料，認為同菌種與不同菌種腹膜炎是彼此競爭的，資料分析包含被設限之病患，因此使用較多樣本數。最後，本論文以中部某醫學中心所提供資料為例，說明若僅收集發病之個案來進行統計分析，可能導致不一致的結論，並闡明以競爭風險觀念處理此資料的優點。

Peritonitis is a serious complication for peritoneal dialysis patients, in which the causes include diabetics, cardiovascular disease, catheter position etc. In this thesis, repeated and nonrepeated peritonitis are concerned. A patient is followed-up until the first peritonitis is observed. In clinical analysis, physicians often used the data from the patients who have developed peritonitis. However, it will make truncated data and lead to inference biases. Here, we adopt the aspect of competing risk to deal with the data because repeated and nonrepeated peritonitis compete each other. Besides we can get larger sample size of data. We illustrate these aspects by analyzing the data from a medical center in Taichung City of Taiwan.

論文口試委員會審定書 I
謝誌 II
中文摘要 III
英文摘要 IV
目錄 V
第一章 導論 1
1.1 前言 1
1.2 血液透析與腹膜透析 3
1.2.1 何謂HD? 3
1.2.2 何謂PD? 5
1.3 腹膜透析導致的腹膜炎 7
第二章 腹膜炎資料與醫學常用方法 10
2.1 資料 10
2.2 醫學常用方法 13
第三章 柯克斯模型分析 15
第四章 競爭風險資料 22
第五章 結論 24
參考文獻 25
附錄 26

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