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研究生:黃欣儀
研究生(外文):Sin-Yi Huang
論文名稱:探討1-aminopyrene誘導斑馬魚胚胎及心血管毒性與血管內皮細胞毒性反應之相關機制
論文名稱(外文):1-aminopyrene induced embryo- and cardio- toxicology in zebrafish, molecular mechanisms of toxic effects in vascular endothelial cells.
指導教授:李宣信李宣信引用關係、關宇翔關宇翔引用關係
指導教授(外文):Shiuan-Shinn Lee、Yu-Hsiang Kuan
口試委員:楊建洲、陳春榮、陳文英
口試委員(外文):Jiann-Jou Yang、Chun-Jung Chen、Wen-Ying Chen
學位類別:碩士
校院名稱:中山醫學大學
系所名稱:公共衛生學系
學門:醫藥衛生學門
學類:公共衛生學類
論文種類:學術論文
論文出版年:2022
畢業學年度:110
語文別:中文
論文頁數:87
中文關鍵詞:1-aminopyrene、心血管疾病、毒性反應、胚胎毒性、心血管毒性
外文關鍵詞:1-aminopyrene、Cardiovascular disease、Toxic effects、Embryotoxicity、Cardiovascular toxicity
相關次數:
  • 被引用被引用:0
  • 點閱點閱:77
  • 評分評分:
  • 下載下載:0
  • 收藏至我的研究室書目清單書目收藏:0
誌謝 II
目錄 III
縮寫表 IV
中文摘要 VII
英文摘要 VIII
壹、 文獻回顧 1
一、 心血管疾病 2
二、 血管內皮細胞與細胞通透性 3
三、 細胞凋亡 (Apoptosis) 4
(一)、 內、外源性路徑 4
(二)、 半胱天冬酶 (Caspases) 5
(三)、 Bcl-2 Family 5
四、 DNA damage 6
五、 氧化壓力及發炎反應 7
(一)、 活性氧物質 7
(二)、 抗氧化酶 8
(三)、 一氧化氮合酶 8
(四)、 MAPKs 9
(五)、 NF-κB 9
六、 斑馬魚 10
七、 1-Aminopyrene 12
貳、 研究動機 13
參、 材料與方法 15
肆、 結果 29
伍、 討論 43
陸、 結論 48
柒、 圖表 51
捌、 參考文獻 76

 
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