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研究生:劉美辰
研究生(外文):Mei-Chen Liu
論文名稱:自體免疫對慣性流產之相關統計
論文名稱(外文):Autoimmune statistics on inertia abortion
指導教授:李明偉李明偉引用關係
指導教授(外文):Ming-Wei Lee
學位類別:碩士
校院名稱:中山醫學大學
系所名稱:醫學檢驗暨生物技術學系
學門:醫藥衛生學門
學類:醫學技術及檢驗學類
論文種類:學術論文
論文出版年:2019
畢業學年度:107
語文別:中文
論文頁數:49
中文關鍵詞:不孕症、連續流產、自體免疫疾病、栓塞
外文關鍵詞:infertility、continuous abortion、autoimmune disease、embolism
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在世界衛生組織(WHO)的定義,所謂不孕症(Infertility),是指一對男女規律的進行沒有避孕措施的性生活,一年或更久無法懷孕,而不孕症目前在我國逐年升高的一種病症。造成不孕症的原因有很多種,其中一種原因為連續流產。造成流產的原因有很多種,包含遺傳學異常、子宮或子宮頸結構異常、感染、環境、藥物因素和賀爾蒙分泌異常及自體免疫疾病。連續流產的患者中有小部分的患者是因為自體免疫性疾病以及凝血功能造成的。本文要來探討,流產一次或流產兩次以上的病患在自體免疫疾病的檢驗中,是否有差異,並探討何種檢驗項目在連續流產的病患比較有影響。本文共收集了37位年齡介於20歲至40歲的病患的檢驗數據,其中一次流產的患者有22人,兩次流產以上的患者有15人。本研究之數據利用SPSS及EXCELL的資料分析來統計。研究結果證實一次流產及流產兩次以上的檢驗數值並沒有顯著差異,並發現D-Dimer、Protein S、ATA及TPO的檢驗數值的不正常在這些患者佔很大的影響。
In the definition of the World Health Organization (WHO), the so-called infertility (infertility) refers to the sexual life of a pair of men and women without contraception, one year or more cannot be pregnant, infertility is currently in Taiwan An elevated condition. There are many reasons for infertility, one of which is continuous abortion. There are many causes of miscarriage, including genetic abnormalities, uterine or cervical structural abnormalities, infections, the environment, drug factors and hormone secretion abnormalities and autoimmune diseases. A small proportion of patients with continuous abortion are caused by autoimmune diseases and coagulation. This article will discuss whether there is a difference in the test of autoimmune diseases in patients with abortion or abortion twice, and to explore which test items are more effective in patients with continuous abortion. This article collected data from 37 patients aged between 20 and 40 years, including 22 patients with a miscarriage and 15 patients with more than two abortions. The data of this study were statistically analyzed using SPSS and EXCELL data analysis. The results of the study confirmed that there was no significant difference in the test values of more than two births and abortions, and found that abnormalities in the test values of d-dimer, protein S, ATA and TPO accounted for a large effect in these patients.
中文摘要…………………………………………………………................ i
英文摘要…………………………………………………………........... ii
目錄…………………………………………………………................ iii
圖目錄…………………………………………………………................... iv
表目錄…………………………………………………………................. v
第一章研究動機 ……………………………………………………………… 1
第二章文獻探討………………………………………………………..………… 2
第一節不孕症簡介………………………………………………….………. 2
第二節甲狀腺自體免疫疾病……………………………………….…. 13
第三節血栓栓塞對於連續流產的影響.……………………….…. 15
第四節其他免疫相關對於連續流產的影響.…………………… 19
第三章材料與方法………………………………………………………..….… 23
第四章資料分析………………………………………………………..………… 38
第五章結果………………………………………………………………..………… 38
第六章討論………………………………………………………………..………… 42
參考文獻……………………………………………………………………… 44
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