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研究生:李彥良
研究生(外文):LEE, YEN-LIANG
論文名稱:基於區塊鏈技術構建以個人為中心的健康資訊交換網絡之研究
論文名稱(外文):Research on the construction of a personal-centered health information exchange network with blockchain technology
指導教授:邱泓文邱泓文引用關係、徐建業徐建業引用關係
指導教授(外文):CHIU, HUNG-WEN、HSU, CHIEN-YEH
口試委員:蘇家玉、張資昊、簡文山、湯世昌、張禾坤、徐建業、邱泓文
口試委員(外文):SU,CHIA-YU、CHANG,TZU-HAO、JIAN, WEN-SHAN、TANG, SHIH-TSANG、CHANG, HER-KUN、HSU, CHIEN-YEH、CHIU, HUNG-WEN
口試日期:2021-12-17
學位類別:博士
校院名稱:臺北醫學大學
系所名稱:醫學資訊研究所博士班
學門:醫藥衛生學門
學類:醫學技術及檢驗學類
論文種類:學術論文
論文出版年:2022
畢業學年度:110
語文別:英文
論文頁數:72
中文關鍵詞:區塊鏈、星際檔案系統、代理再加密、FHIR、CDA R2
外文關鍵詞:Blockchain、InterPlanetary File System、Proxy Re-encryption、FHIR、CDA R2
相關次數:
  • 被引用被引用:0
  • 點閱點閱:179
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Table of Contents
誌 謝 iv
Acronyms List 1
摘要 2
Abstract 5
Chapter 1 Introduction 9
1.1. EMR development in Taiwan 9
1.2. My Health Bank in Taiwan 11
1.3. EMR/EHR/PHR 12
1.4. Motivation and Objects 13
Chapter 2 Literature Review 15
2.1. Personal Health Information and Standards 15
2.2. Health Information Exchange and Blockchain 20
Chapter 3 Materials and Methods 27
3.1. Blockchain Technology 27
3.1.1. Consensus 30
3.1.2. Peer-to-Peer Technology 31
3.1.3. Smart Contract 33
3.1.4. Oracle 34
3.2. InterPlanetary File System (IPFS) 35
3.2.1. File System 35
3.2.2. Cluster Network 39
3.3. Cryptography 41
3.3.1. Data Encryption 41
3.3.2. Proxy Re-Encryitopn 45
Chapter 4 Results 47
4.1. Network Architecture and Roles 47
4.2. Data Access Follow 52
4.3. The Benefit 56
Chapter 5 Discussion 60
Chapter 6 Conclusion 64
References 66

List of Tables
Table 1:The compression of blockchain platforms 29

List of Figures
Figure 1:Concept of Blockchain by Satoshi. Nakamoto 27
Figure 2:KEM/DEM Hybrid Encryption 44
Figure 3 : Proxy Re-Encryption Scheme 45
Figure 4 : Distributed Network Architecture and Roles 47
Figure 5:Health information owner 49
Figure 6:Health Information Requester 50
Figure 7:EMR/EHR/PHR upload flow 52
Figure 8:EMR/EHR/PHR Data Re-Encryption flow 54



[1] AHIMA e-HIM Personal Health Record Work Group, "Defining the personal health record," Defining the Personal Health Record/AHIMA, American Health Information Management Association, 2005.
[2] Jae-woo Lee et al., "The development and implementation of stroke risk prediction model in National Health Insurance Service's personal health record," Computer Methods and Programs in Biomedicine, vol. 153, pp. 253-257, 2018/01/01/ 2018.
[3] Soon-Ae Shin, Dong-Soo Choo, Tae-Hwa Han, Jong-Heon Park, Jong-Hee Kim, and Ji-Hyon Bang, "NHIS Big Data and Health Services," 2015.
[4] Anton Hasselgren, Katina Kralevska, Danilo Gligoroski, Sindre A. Pedersen, and Arild Faxvaag, "Blockchain in healthcare and health sciences—A scoping review," International Journal of Medical Informatics, vol. 134, p. 104040, 2020/02/01/ 2020.
[5]Matthias Mettler, "Blockchain technology in healthcare: The revolution starts here," in 2016 IEEE 18th international conference on e-health networking, applications and services (Healthcom), 2016, pp. 1-3: IEEE.
[6]Ariel Ekblaw, Asaph Azaria, John D Halamka, and Andrew Lippman, "A Case Study for Blockchain in Healthcare:“MedRec” prototype for electronic health records and medical research data," in Proceedings of IEEE open & big data conference, 2016, vol. 13, p. 13.
[7]Abdullah Al Omar, Md Zakirul Alam Bhuiyan, Anirban Basu, Shinsaku Kiyomoto, and Mohammad Shahriar Rahman, "Privacy-friendly platform for healthcare data in cloud based on blockchain environment," Future Generation Computer Systems, vol. 95, pp. 511-521, 2019/06/01/ 2019.
[8]Peng Zhang, Jules White, Douglas C. Schmidt, Gunther Lenz, and S. Trent Rosenbloom, "FHIRChain: Applying Blockchain to Securely and Scalably Share Clinical Data," Computational and Structural Biotechnology Journal, vol. 16, pp. 267-278, 2018/01/01/ 2018.
[9]Kevin Peterson, Rammohan Deeduvanu, Pradip Kanjamala, and Kelly Boles, "A blockchain-based approach to health information exchange networks," in Proc. NIST Workshop Blockchain Healthcare, 2016, vol. 1, pp. 1-10.
[10] Lei Xu et al., “Building a dynamic searchable encrypted medical database for multiclient,”Information Sciences, vol. 527, pp. 394-405, 2020.
[11] Huige Li, Haibo Tian, Fangguo Zhang and Jiejie He, “Blockchain-based searchable He, “Blockchain-based searchable symmetric encryption scheme,” Computers & Electrical Engineering, vol. 73, pp. 32-45, 2019.
[12] Lanxiang Chen et al., “Blockchain based searchable encryption for electronic health record sharing,” Future Generation Computer Systems, vol. 95, pp. 420-429, 2019.
[13] Shangping Wang, Dan Zhang and Yaling Zhang, “Blockchain-based personal health records sharing scheme with data integrity verifiable,” IEEE Access, vol. 7, pp. 102887-102901, 2019.
[14] Shufen Niu, Lixia Chen, Jinfeng Wang and Fei Yu, “Electronic health record sharing scheme with searchable attribute-based encryption on blockchain,” IEEE Access, vol.8, pp. 7195-7204, 2020.
[15] Roehrs, A.; Da Costa, C.A.; Righi, R.D.R.; Farias, K. Personal Health Records: A Systematic Literature Review. J. Med. Internet Res. 2017, 19, e13.
[16] DSTU Fhir Fhir. 1 (V0. 0.82): Welcome to FHIR. 2015. Available online: https://hl7.org/FHIR/ (accessed on 26 April 2020).
[17] Schleyer, T.K.; Rahurkar, S.; Baublet, A.M.; Kochmann, M.; Ning, X.; Martin, U.K.; Finnell, J.T.; Kelley, K.W.; FHIR Development Team; Schaffer, J.T. Preliminary evaluation of the Chest Pain Dashboard, a FHIR-based approach for integrating health information exchange information directly into the clinical workflow. AMIA Summits Transl. Sci. Proc. 2019, 2019, 656.
[18] Goodman, A.B.; Braun, P.; Braunstein, M. Healthy Weight on Fhir-Innovative Technology to Support High Quality Clinical Care & Clinical to Community Linkages for Child Obesity; American Academy of Pediatrics: Itasca, IL, USA, 2018.
[19] Baihan, M.S.; Sánchez, Y.K.R.; Shao, X.; Gilman, C.; Demurjian, S.A.; Agresta, T.P. A Blueprint for Designing and Developing M-Health Applications for Diverse Stakeholders Utilizing FHIR. In Contemporary Applications of Mobile Computing in Healthcare Settings; IGI Global: New York, NY, USA, 2018; pp. 85–124.
[20] Daumke, P.; Heitmann, K.U.; Heckmann, S.; Martínez-Costa, C.; Schulz, S. Clinical Text Mining on FHIR. Stud. Health Technol. Inform. 2019, 264, 83–87.
[21] Storck, M.; Hollenberg, L.; Dugas, M.; Soto-Rey, I. Interoperability Improvement of Mobile Patient Survey (MoPat) Implementing Fast Health Interoperability Resources (FHIR). Stud. Health Technol. Inform. 2019, 258, 141–145.
[22] Giordanengo, A.; Bradway, M.; Grøttland, A.; Hartvigsen, G.; Årsand, E. A FHIR-Based Data Flow Enabling Patients with Diabetes to Share Self-Collected Data with the Norwegian National Healthcare Systems and Electronic Health Records Systems; Mary Ann Liebert,Inc.: New Rochelle, NY, USA, 2019.
[23] Kiourtis, A.; Mavrogiorgou, A.; Menychtas, A.; Maglogiannis, I.; Kyriazis, D. Structurally Mapping Healthcare Data to HL7 FHIR through Ontology Alignment. J. Med. Syst. 2019, 43, 62.
[24] Gøeg, K.R.; Rasmussen, R.K.; Jensen, L.;Wollesen, C.M.; Larsen, S.; Pape-Haugaard, L. A future-proof architecture for telemedicine using loose-coupled modules and HL7 FHIR. Comput. Methods Programs Biomed. 2018, 160, 95–101.
[25] Alper, B.; Mayer, M.; Shahin, K.; Richardson, J.; Schilling, L.; Tristan, M.; Salas, N. 20 Achieving evidence interoperability in the computer age: Setting evidence on FHIR. BMJ Evid. Based Med. 2019, 24 (Suppl. S1), A15.
[26] Lackerbauer, A.M.; Lin, A.C.; Krauss, O.; Hearn, J.; Helm, E. A Model for Implementing an Interoperable Electronic Consent Form for Medical Treatment Using HL7 FHIR. Eur. J. Biomed. Inform. 2018, 14.
[27] Dixon, B.E.; Taylor, D.E.; Choi, M.; Riley, M.; Schneider, T.; Duke, J. Integration of FHIR to Facilitate Electronic Case Reporting: Results from a Pilot Study. Stud. Health Technol. Inform. 2019, 264, 940–944.
[28] Hussain, M.A.; Langer, S.G.; Kohli, M.D. Learning HL7 FHIR Using the HAPI FHIR Server and Its Use in Medical Imaging with the SIIM Dataset. J. Digit. Imaging 2018, 31, 334–340.
[29] Roehrs, A.; Da Costa, C.A.; Righi, R.D.R.; Rigo, S.J.; Wichman, M.H. Toward a Model for Personal Health Record Interoperability. IEEE J. Biomed. Health Inform. 2019, 23, 867–873.
[30] Martinez-Garcia, A.; Garcia-Garcia, J.A.; Escalona, M.J.; Parra-Calderón, C. Working with the HL7 metamodel in a Model Driven Engineering context. J. Biomed. Inform. 2015, 57, 415–424.
[31] Walderhaug, S.; Stav, E.; Mikalsen, M. Experiences from Model-Driven Development of Homecare Services: UML Profiles and Domain Models; Springer: Berlin/Heidelberg, Germany, 2008.
[32] González-Ferrer, A.; Peleg, M.; Verhees, B.; Verlinden, J.-M.; Marcos, C. Data integration for clinical decision support based on open EHR archetypes and HL7 virtual medical record. In Process Support and Knowledge Representation in Health Care; Springer: Berlin/Heidelberg, Germany, 2012; pp. 71–84.
[33] Simon, S.K.; Anbananthen, K.S.M.; Lee, S. A Ubiquitous Personal Health Record (uPHR) Framework; Atlantis Press: Paris, France, 2013.
[34] Fontelo, P.; Rossi, E.M.; Ackerman, M.J.; Marceglia, S. A Standards-Based Architecture Proposal for Integrating Patient mHealth Apps to Electronic Health Record Systems. Appl. Clin. Inform. 2015, 6, 488–505.
[35] Fonda, S.J.; Kedziora, R.J.; Vigersky, R.A.; Bursell, S.-E. Evolution of a web-based, prototype Personal Health Application for diabetes self-management. J. Biomed. Inform. 2010, 43, S17–S21.
[36] Backonja, U.; Kim, K.; Casper, G.R.; Patton, T.; Ramly, E.; Brennan, P.F. Edmond Ramly and Patricia Flatley Brennan. Observations of daily living: Putting the “personal” in personal health records. In Proceedings of the NI 2012: 11th International Congress on Nursing Informatics, Montreal, QC, Canada, 23–27 June 2012.
[37] Ferguson, G.; Quinn, J.; Horwitz, C.; Swift, M.; Allen, J.; Galescu, L. Towards a Personal Health Management Assistant. J. Biomed. Inform. 2010, 43, S13–S16.
[38] Duckett, S. and S. Willcox, The Australian health care system. 2015: Oxford University Press.
[39] Lehnbom, E., J. Brien, and A. McLachlan, Knowledge and attitudes regarding the personally controlled electronic health record: an Australian national survey. Internal medicine journal, 2014. 44(4): p. 406-409.
[40] Gunter, T.D. and N.P. Terry, The emergence of national electronic health record architectures in the United States and Australia: models, costs, and questions. Journal of medical Internet research, 2005. 7(1): p. e3.
[41] Andrews, L., R. Gajanayake, and T. Sahama, The Australian general public's perceptions of having a personally controlled electronic health record (PCEHR). International Journal of Medical Informatics, 2014. 83(12): p. 889-900.
[42] Lehnbom, E., H. Douglas, and M. Makeham, Positive beliefs and privacy concerns shape the future for the Personally Controlled Electronic Health Record. Internal medicine journal, 2016. 46(1): p. 108-111.
[43] Hanna, L., et al., Patient perspectives on a personally controlled electronic health record used in regional Australia: ‘I can be like my own doctor’. Health Information Management Journal, 2017. 46(1): p. 42-48.
[44] Pearce, C. and M. Bainbridge, A personally controlled electronic health record for Australia. Journal of the American Medical Informatics Association, 2014. 21(4): p. 707-713.
[45] A .S. Manoj , M.A . Hussain , P.S. Teja , in: Patient Health Monitoring Using IOT, in Mobile Health Applications for Quality Healthcare Delivery, IGI Global, 2019, pp. 30–45 .
[46] S. Misbahuddin , et al. , IoT-based ambulatory vital signs data transfer system, J. Comput. Netw. Commun. 2018 (2018) .
[47] F. Jamil , et al. , Towards a remote monitoring of patient vital signs based on IoT-based blockchain integrity management platforms in smart hospitals, Sen- sors 20 (8) (2020) 2195 .
[48] K.N. Swaroop , et al. , A health monitoring system for vital signs using IoT, In- ternet of Thing. 5 (2019) 116–129 .
[49] Kathy J. MONTGOMERY , Development of a Tele-Healthcare Clinical Practice Guideline for Diabetic Patients, Walden University, 2019 .
[50] W.E. Hills , K.T. Hills , Tele-health care and the use of virtual communication technologies in medical research and application: the future of telemedicine is now!, Med. Sci. Pulse 14 (3) (2020)
[51] R. Islam , et al. , Portable Health Clinic: an Advanced Tele-Healthcare System for Unreached Communities, Stud. Health Technol. Inform. 264 (2019) 616–619 .
[52] J. Benaloh , et al. ,Patient controlled encryption: ensuring privacy of electronic medical records, in: Proceedings of the 2009 ACM workshop on Cloud com- puting security, 2009 .
[53] Chor, B., et al. Private Information Retrieval. IEEE.
[54] Z. Xia , et al. , EPCBIR: an efficient and privacy-preserving content-based image retrieval scheme in cloud computing, Inf. Sci. (Ny) 387 (2017) 195–204 .
[55] Giuseppe ATENIESE , et al. , Provable data possession at untrusted stores, in: Proceedings of the 14th ACM conference on Computer and communications se- curity , ACM Digital Library, 2007, pp. 598–609 .
[56] Giuseppe ATENIESE , et al. , in: Scalable and efficient provable data possession, ACM Digital Library, 2008, pp. 1–10 .
[57] H. Wang , et al. , Provable data possession with outsourced data transfer, IEEE Trans. Serv. Comput. (2019) .
[58] A. Tembhare , et al. , Role-based policy to maintain privacy of patient health records in cloud, J. Supercomput. 75 (9) (2019) 5866–5881 .
[59] L. Xu , C. Xu , X. Zhang , A secure and efficient E-medical record system via searchable encryption in public platform, KSII Trans. Internet Inform. Syst. (TIIS) 11 (9) (2017) 4624–4640 .
[60] J. Daemen , V. Rijmen , in: Announcing the Advanced Encryption Standard (aes), Federal Information Processing Standards Publication, 2001, p. 197 .
[61] M. Calderbank , The Rsa cryptosystem: History, algorithm, Primes, math. uchicago. edu, Chicago, 2007 .
[62] Satoshi. NAKAMOTO Bitcoin , A peer-to-peer electronic cash system, Decentral- ized Business Review (2008) 21260 .
[63] Li YC, Yen JC, Chiu WT, Jian WS, Syed-Abdul S, Hsu MH. Building a national electronic medical record exchange system - experiences in Taiwan. Comput Methods Programs Biomed. 2015 Aug;121(1):14-20. doi: 10.1016/j.cmpb.2015.04.013. Epub 2015 May 5. PMID: 26001420.
[64] Huang SK, Wang PJ, Tseng WF, Syu FK, Lee MC, Shih RL, Sheen MT, Chen MS. NHI-PharmaCloud in Taiwan--A preliminary evaluation using the RE-AIM framework and lessons learned. Int J Med Inform. 2015 Oct;84(10):817-25. doi: 10.1016/j.ijmedinf.2015.06.001. Epub 2015 Jun 22. PMID: 26113462.
[65] Huang SK, Pan YT, Chen MS. My Health Bank 2.0-making a patron saint for people's health. J Formos Med Assoc. 2017 Feb;116(2):69-71. doi: 10.1016/j.jfma.2016.05.008. Epub 2016 Jul 13. PMID: 27421173.
[66] Orhan K, Bayrakdar IS, Celik O, Ayan B, Polat E. Can the blockchain-enabled interplanetary file system (Block-IPFS) be a solution for securely transferring imaging data for artificial intelligence research in oral and maxillofacial radiology? Imaging Sci Dent. 2021 Sep;51(3):337. doi: 10.5624/isd.20210144. Epub 2021 Aug 11. PMID: 34621663; PMCID: PMC8479440.
[66] Deborah, Aleburu and Afolashade, Kuyoro and Lossan, Bonde and Adenrele, Afolorunso, Blockchain: A Possible Alternative to Achieving Health Information Exchange (HIE) (2020). International Journal of Innovative Research in Computer Science & Technology (IJIRCST), ISSN: 2347-5552, Volume-8, Issue-3, May 2020 , Available at SSRN: https://ssrn.com/abstract=3670837
[68] Yen-Liang Lee, Hsiu-An Lee, Chien-Yeh Hsu, Hsin-HuaKung, Hung-WenChiuag, “SEMRES - A Triple Security Protected Blockchain Based Medical Record Exchange Structure” Computer Methods and Programs in Biomedicine, vol. 215, March 2022, 106595
[69] Yen-Liang Lee, Hsiu-An Lee, Chien-Yeh Hsu, Hsin-HuaKung, Hung-WenChiuag, “"Implement an International Interoperable PHR by FHIR—A Taiwan Innovative Application"”Sustainability , vol. 13, 2021, 198.

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