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拾壹、參考文獻
壹、前言
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參-一、藥物動力學與藥物藥效學的定義及影響因素
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肆-一、果汁與藥物的交互作用
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J. J., Cnubben, N. H. P., Groten, J. P., Bladeren, P. J.
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7. Chiang, H. M., Fang, S. H., Wen, K. C., Hsiu, S. L.,
Tsai, S. Y., Hou, Y.C., Chia, Y. C. and Chao, P. D. L.
(2005) Life-threatening interaction between the root
extract of Pueraria lobata and methotrexate in rats.
Toxicology and Applied Pharmacology 209: 263-268.
8. Pal, D. and Mitra, A. K. (2006) MDR- and CYP3A4-mediated
drug-herbal interactions. Life Sciences 78: 2131-2145.
9. Wang, Y. H., Chao, P. D. L., Hsiu, S. L., Wen, K. C. and
Hou, Y. C. (2004) Lethal quercetin-digoxin interaction
in pigs. Life Sciences 74: 1191-1197.
10. Patsalos, P. N. and Perucca, E. (2003) Clinically
important drug interactions in epilepsy: general
features and interactions between antiepileptic drugs.
Lancet Neurology 2: 347–356.
11. Manzi, S. and Shannon, M. (2005) Drug interactions: A
review. ClinicalPediatric Emergency Medicine 6: 93-102.
12. Byrne, B. E. (2003) Drug interactions: A review and
update. Endodontic Topics 4: 9-21.
13. Morawiecka, I. B. (2000) Cisapride (PrepulsidR):
Interactions with grapefruit and drugs. Canadian
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14. Kakar, S. M., Paine, M. F., Stewart, P. W. and Watkins,
P. B. (2004) 6' 7' -dihydroxybergamottin contributes to
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Wanwimolruk, S. (2000) Content of CYP3A4 inhibitors,
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20. Wittkowsky, A. K. (2005) A systematic review and
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21. Singh, Y. N. (2005) Potential for interaction of kava
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of Dental Hygiene 2: 111-121.
25. Magee, K. A. (2005) Herbal therapy: A review of
potential health risks and medicinal interactions.
Orthodontics Craniofacial Researches 8: 60-74.
26. Izzo, A. A., Carloa, G. D., Borrellia, F. and Ernst, E.
(2005) Cardiovascular pharmacotherapy and herbal
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T. F. and Hollenberg, P. F. (1998) Inactivation of
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29. Dresser, G. K., Bailey, D. G.and Carruthers, S. G.
(2000). Grapefruit juice-felodipine interaction in
the elderly. Clinical Pharmacology and Therapeutics 68:
28-34.
30. Kakar, S. M., Paine, M. F., Stewart, P. W.and Watkins,
P. B. (2004)6'7'-dihydroxybergamottin contributes to
the grapefruit juice effect. Clinical Pharmacology and
Therapeutics 75: 569-79.
31. Edwards, D. J., Fitzsimmons, M. E., Schuetz, E. G.,
Yasuda, K., Ducharme, M. P., Warbasse, L. H.,Woster,
P. M., Schuetz, J. D. and Watkins, P. (1999) 6'7'-
dihydroxybergamottin in grapefruit juice and seville
orange juice: Effects on cyclosporine disposition,
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Grapefruit juice-drug interaction. British Journal of
Clinical Pharmacology 46: 101-110.
34. Izzo, A. A. (2004) Herb–drug interactions: An overview
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35. Girennavar, B., Poulose. S. M., Jayaprakasha, G. K.,
Bhata, N. G. and Patila, B. S. (2006) Furocoumarins
from grapefruit juice and their effect on human CYT
3A4 and CYT 1B1 isoenzymes. Bioorganic & Medicinal
Chemistry 14: 2606–2612.
36. Goosen, T. C., Cillie, D., Bailey, D. G., Yu, C., He,
K., Hollenberg, P. F.,Woster, P. M., Cohen, L.,
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CYT 3A4 activity by grapefruit Juice flavonoid,
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38. Odou, P., Ferrari, N., Barthe’ le’my, C., Brique, S.,
Lhermitte, M., Vincent, A. and Libersa, C.and
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mechanisms. Journal of Clinical Pharmacology and
Therapeutics 30: 153–158.
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40. Lilja, J. J., Patinen, L. J. and Neuvonen, P. J.
(2004). Orange juice Substantially reduces The
bioavailability of the β-adrenergic-blocking agent
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圖解藥理學，合記圖書，台北， pp. 65-66。
42. Bailey. D. G. (2004) Grapefruit juice–drug interaction
issues. Handbook of Drug-Nutrient Interaction. (Ch 9)
Humana Press, Totowa, USA. Ed. by Boulilata, J. I.
and Armenti, V. T. pp. 175-194.
43. 高惠娟編譯，呂嘉陞修訂。(1997) 第十五章，用於治療高血壓的藥物，
圖解藥理學，合記圖書，台北， p. 66。
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社，台北， pp. 188-189。
45. 高惠娟編譯，呂嘉陞修訂。(1997) 第十五章，用於治療高血壓的藥物，
圖解藥理學，合記圖書，台北， p. 66。
46. Bailey, D.G., Bend,J. R., Arnold, M. O., Tran, L.T.and
Spence, J. D. (1996) Erythromycin-felodipine
interaction: Magnitude, mechanism, and comparison with
grapefruit juice. Clinical pharmacology and
therapeutics 60: 25-33.
47. Wunderlich, S. M. (2004) Food and drug interactions.
Handbook of drug interactions. Humana Press, Totowa,
USA. Ed. by Mozayani, A., Raymon, L. P. pp.379-392.
48. Hu, Z., Yang, X., Ho, P. C., Chan, S. Y., Heng, P.
W., Chane, E., Duan, W., Koh, H. L. and Zhou, S. (2005)
Herbdrug interactions: A literature review. Drugs 65:
1239-82.
49. Anderson, K. E. (2004) Effects of specific foods and
non-nutritive dietary components on drug metabolism.
Handboodk of Drug-Nutrient Interaction. (Ch 8)
Humana Press, Totowa. USA. Ed. by Boulilata, J. I. and
Armenti, V. T. pp. 155-173.
50. Iza, M. (2000) Cisapride (PrepulsidR): Interactions
with grapefruit and drugs. Canadian Medical Association
162: 105-106.
51. 楊聖信、許桂森、林君穎、張國志合譯. (1996) 第四十七章，細菌核
醣體作用抑制劑，人體藥理學，藝軒圖書出版社，台北，pp. 663-664。
52. Sahi, J., Reyner, E. L., Bauman, J. N., Gueneva-
Boucheva, K. and Burleigh, J. (2002) The effect of
begamottine on diazepam plasma levels and P450 enzymes
in beagle dogs. Drug Metabolism and Disposition 30:
135–140.
53. Ho, P. C. and Saville, D. J. (2001) Inhibition of human
CYT 3A4 activity by grapefruit Juice flavonoid,
furanocoumarines and related compounds. Journal
Pharmacy Pharmaceutical Sciences 4: 217-277.
54. Bailey, D. G., Dresser, G. K. and Bend, J. R. ( 2003).
Bergamottin, lime juice, and red wine as inhibitors of
cytochrome P450 3A4 activity: Comparison with
grapefruit juice. Clinical Pharmacology and
Therapeutics 73: 529-537.
55. Grenier, J., Fradette, C., Morelli, G., Merritt, G. J.,
Vranderick, M. and Ducharme, M. P. (2006) Pomelo juice,
but not cranberry juice, affects the pharmacokinetics
of cyclosporine in humans. American Society for
Clinical Pharmacology and Therapeutics 79: 255-262.
56. Dresser, G. K., Bailey, D. G., Leake, B. F.,
Schwarz, U. I., Dawson, P. A.,Freeman, D. J. and Kim,
R. B. (2002) Fruit juices inhibit organic anion
transporting polypeptide–mediated drug uptake to
decrease the oral availability of fexofenadine.
American Society for Clinica Pharmacology and
Therapeutics 71: 11-20.
肆-二、牛乳與藥物之交互作用
1. Maniscalco, B. S. and Taylor, K. A. (2004) Calcification
in coronary artery disease can be reversed by EDTA-
tetracycline long-term chemotherapy. Pathophysiology 11:
95–101.
2. Wunderlich, S. M. (2004) Food and drug interactions.
Handbook of Drug Interactions. (Ch 19) Humana Press,
Totowa, USA. Ed. by Mozayani, A.and Raymon, L. P. pp.
379-392.
3、林松洲編譯。(1999) 第十八章，化學療法、消毒，應用藥理學，
豪峰出版社，台北， pp. 571-572。
4. 高惠娟編譯，呂嘉陞修訂。(1997) 第三十七章，抑制蛋白質合成
的抗微生物藥物，圖解藥理學，合記圖書，台北， p. 177。
5. Cross, J. T. (2001) Fluoroquinolones. Seminars in
Pediatric Infectious Diseases 12: 211-223.
6. Joseph M.and Blondeau, J. M. (2004) Fluoroquinolones:
Mechanism of action, classification, and development of
resistance. Survery of Ophthlmology 49: S73-S77.
7. Manzi, S. and Shannon, M. (2005) Drug interactions: A
review. clinical Pediatric Emergency Medicine 6: 93-102.
8. Psomas, G., Tarushi, A., Efthimiadou, E. K., Sanakis,
Y., Raptopoulou, C. P.and Katsaros, N. (2006) Synthesis,
structure and biological activity of copper (II)
complexes with oxolinic acid. Journal of Inorganic
Biochemistry 100: 1764–1773.
9. Knight-Klimas, T. C. and Boullata, J. I. (2004) Drug–
nutrient interactions in the elderly. Handbook of Drug-
Nutrient Interaction. (Ch 20) Humana Press, Totowa, USA.
Ed. by Boullata, J. I. and Armenti, V. T. pp. 363-410.
10. Btaiche, I. F. and Kraft, M. D. Nutrients that may
optimize drug effects. Handbook of Drug–Nutrient
Interactions. (Ch.10) Humana Press, Totowa, USA. Ed. by
Boullata, J. I. and Armenti, V. T. pp. 195-216.
肆-三、茶、咖啡、酸性飲料與藥物之交互作用
1. Btaiche, I. F. and Kraft, M. D. Nutrients that may
optimize drug effects. Handbook of Drug-Nutrient
Interactions. (Ch 10) Humana Press, Totowa, USA. Ed. by
Boullata, J. I. and Armenti, V. T.pp. 195-216.
2. Knight-Klimas, T. C. and Boullata, J. I. (2004) Drug–
nutrient interactions in the elderly. Handbook of Drug- Nutrient Interaction. (Ch 20)Humana Press, Totowa, USA.
Ed. by Boulilata, J. I., Arnenti, V. T.and Malonem, M.
pp. 363-41.
3. Wunderlich, S. M. (2004) Food and drug interactions.
Handbook of Drug Interactions. (Ch 20) Humana Press,
Totowa, USA. Ed. by Mozayani, A. and Raymon, L. P. pp.
379-392.
肆-四、高脂肪食品與藥物之交互作用
1. Btaiche, I. F. and Kraft, M. D. (2004)Nutrients that may
optimize drug effects. Handbook of Drug–Nutrient
Interactions. (Ch 10) Humana Press, Totowa, USA. Ed. by
Boullata, J. I. and Armenti, V. T. pp.195-216.
2. Knight-Klimas, T. C. and Boullata, J. I. (2004) Drug-
nutrient interactions in the elderly. Handbook of Drug-
Nutrient Interaction. (Ch 20) Humana Press, Totowa, USA.
Ed. by Boulilata, J. I., Arnenti, V. T.and Malonem, M.
pp. 363-410.
3. 林松洲編譯。(1999) 第十八章，化學療法、消毒，應用藥理學，
豪峰出版社，台北，pp. 571-572。
4. Wunderlich, S. M. (2004) Food and drug interactions.
Handbook of Drug Interactions. (Ch 20) Humana Press,
Totowa, USA. Ed. by Mozayani, A.and Raymon, L. P. pp.
379-392.
肆-伍、高蛋白食品與藥物之交互作用
1. Knight-Klimas, T. C. and Boullata, J. I. (2004) Drug–
nutrient interactions in the elderly. Handbook of Drug-
Nutrient Interaction.(Ch 20) Humana Press, Totowa, USA.
Ed. by Boulilata, J. I., Arnenti, V. T.and Malonem, M.
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